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chr19:20,885,811-22,643,745

Best TWAS P=1.19e-12 · Best GWAS P=7.7e-09 conditioned to 0.00156

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	LOC641367	0.26	0.17	enet	16	0.19	4.6e-22	-5.4	-6.5	7.1e-11	0.68	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	ZNF100	0.74	0.50	lasso	14	0.67	2.0e-110	-5.4	-6.4	1.3e-10	0.61	0.01	0.99	FALSE
3	GTEx	Adipose Subcutaneous	ZNF100	0.68	0.34	lasso	12	0.53	1.4e-50	-5.4	-6.2	4.6e-10	0.55	0.01	0.99	FALSE
4	GTEx	Adipose Visceral Omentum	ZNF100	0.65	0.33	lasso	14	0.46	4.9e-26	-5.4	-6.2	4.1e-10	0.59	0.01	0.99	FALSE
5	GTEx	Adrenal Gland	ZNF100	0.48	0.03	lasso	12	0.22	1.4e-08	-3.7	-6.2	5.2e-10	0.64	0.02	0.96	FALSE
6	GTEx	Artery Aorta	ZNF100	0.65	0.20	lasso	11	0.52	3.7e-33	-5.4	-6.2	7.1e-10	0.59	0.01	0.99	FALSE
7	GTEx	Artery Coronary	ZNF100	0.75	0.27	lasso	11	0.50	1.9e-19	-5.4	-5.6	1.9e-08	0.54	0.01	0.99	FALSE
8	GTEx	Artery Tibial	ZNF100	0.64	0.28	lasso	11	0.49	1.1e-43	-5.4	-6.4	1.8e-10	0.59	0.01	0.99	FALSE
9	GTEx	Brain Cerebellar Hemisphere	ZNF493	0.26	0.04	lasso	6	0.15	1.2e-04	2.8	-5.3	9.1e-08	0.36	0.09	0.42	FALSE
10	GTEx	Breast Mammary Tissue	ZNF100	0.65	0.42	lasso	6	0.50	3.0e-29	-5.4	-6.0	1.8e-09	0.54	0.01	0.99	FALSE
11	GTEx	Breast Mammary Tissue (Female)	ZNF100	0.48	0.23	enet	31	0.38	2.0e-12	-4.0	-6.2	7.4e-10	0.68	0.03	0.97	FALSE
12	GTEx	Cells Transformed fibroblasts	ZNF100	0.38	0.16	enet	24	0.30	3.2e-23	-5.4	-5.7	1.3e-08	0.49	0.01	0.99	FALSE
13	GTEx	Colon Sigmoid	ZNF100	0.51	0.26	lasso	5	0.32	3.6e-12	-5.4	-5.3	1.1e-07	0.50	0.01	0.99	FALSE
14	GTEx	Colon Transverse	ZNF100	0.60	0.32	lasso	7	0.41	9.0e-21	-5.4	-6.3	2.6e-10	0.54	0.01	0.99	FALSE
15	GTEx	Esophagus Gastroesophageal Junction	ZNF100	0.69	0.28	enet	28	0.53	2.2e-22	-5.4	-5.7	1.4e-08	0.50	0.01	0.99	FALSE
16	GTEx	Esophagus Mucosa	ZNF100	0.62	0.23	lasso	15	0.43	1.0e-30	-5.4	-6.4	1.2e-10	0.54	0.01	0.99	FALSE
17	GTEx	Esophagus Muscularis	ZNF100	0.64	0.32	enet	31	0.48	8.2e-33	-5.4	-5.5	3.3e-08	0.45	0.01	0.99	FALSE
18	GTEx	Lung	ZNF100	0.70	0.34	lasso	11	0.50	4.6e-43	-5.4	-6.6	3.6e-11	0.64	0.01	0.99	FALSE
19	GTEx	Muscle Skeletal	ZNF100	0.47	0.14	lasso	11	0.36	1.7e-36	-4.0	-6.4	1.5e-10	0.60	0.13	0.86	FALSE
20	GTEx	Nerve Tibial	ZNF100	0.78	0.36	lasso	16	0.55	1.2e-45	-5.4	-6.4	2.0e-10	0.61	0.01	0.99	FALSE
21	GTEx	Ovary	ZNF100	0.63	0.18	lasso	11	0.41	2.7e-11	-5.4	-6.2	6.3e-10	0.60	0.01	0.96	FALSE
22	GTEx	Pancreas	ZNF100	0.62	0.31	lasso	15	0.39	1.2e-17	-5.4	-6.2	4.8e-10	0.56	0.01	0.99	FALSE
23	GTEx	Pituitary	ZNF100	0.71	0.24	enet	27	0.52	1.9e-15	-5.4	-6.5	8.6e-11	0.65	0.01	0.99	FALSE
24	GTEx	Prostate	ZNF100	0.64	0.25	lasso	10	0.48	8.6e-14	-5.4	-5.8	7.2e-09	0.48	0.01	0.99	FALSE
25	GTEx	Skin Not Sun Exposed Suprapubic	ZNF100	0.64	0.15	lasso	11	0.48	4.1e-29	-3.7	-6.5	9.1e-11	0.66	0.49	0.49	FALSE
26	GTEx	Skin Sun Exposed Lower leg	ZNF100	0.58	0.30	enet	32	0.42	8.5e-38	-5.4	-6.8	1.5e-11	0.63	0.01	0.99	FALSE
27	GTEx	Small Intestine Terminal Ileum	ZNF100	0.61	0.24	enet	53	0.39	8.5e-10	-5.4	-7.1	1.2e-12	0.41	0.02	0.95	TRUE
28	GTEx	Spleen	ZNF100	0.47	0.11	enet	26	0.20	8.7e-06	-3.7	-6.1	8.3e-10	0.47	0.06	0.64	FALSE
29	GTEx	Stomach	ZNF100	0.59	0.29	lasso	11	0.40	1.0e-20	-5.4	-6.2	6.9e-10	0.55	0.01	0.99	FALSE
30	GTEx	Thyroid	ZNF100	0.64	0.27	lasso	15	0.47	2.7e-40	-5.4	-6.7	2.6e-11	0.62	0.01	0.99	FALSE
31	GTEx	Whole Blood	ZNF100	0.25	0.12	lasso	5	0.19	2.6e-17	2.8	-5.9	3.5e-09	0.45	0.94	0.02	FALSE
32	METSIM	Adipose	ZNF100	0.30	0.14	enet	18	0.22	4.0e-33	-5.4	-6.6	5.4e-11	0.65	0.01	0.99	FALSE
33	NTR	Blood	ZNF100	0.12	0.05	lasso	8	0.06	2.3e-18	-5.4	-6.0	1.8e-09	0.55	0.01	0.99	FALSE
34	ROSMAP	Brain Pre-frontal Cortex	ZNF100	0.21	0.07	enet	20	0.10	2.8e-13	-4.0	-5.7	1.2e-08	0.62	0.04	0.69	FALSE
35	YFS	Blood	ZNF100	0.02	0.00	enet	22	0.01	3.3e-04	-5.4	-6.4	1.4e-10	0.45	0.02	0.88	FALSE