Best TWAS P=6.07e-31 · Best GWAS P=1.66e-29 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | AGT | 0.67 | 0.50 | enet | 12 | 0.40 | 3.4e-11 | 11.01 | -11.1 | 9.7e-29 | -0.98 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Brain Cerebellum | AGT | 0.60 | 0.40 | lasso | 6 | 0.36 | 1.4e-11 | 11.28 | 11.6 | 6.1e-31 | 0.96 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | COG2 | 0.05 | 0.02 | blup | 137 | 0.02 | 7.8e-05 | 4.12 | 5.2 | 2.6e-07 | 0.22 | 0.87 | 0.01 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | AGT | 0.07 | 0.05 | lasso | 3 | 0.04 | 3.6e-03 | 5.91 | 7.3 | 2.8e-13 | 0.89 | 0.01 | 0.96 | TRUE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | AGT | 0.07 | 0.02 | enet | 12 | 0.04 | 1.8e-05 | 8.97 | 11.5 | 1.0e-30 | 0.76 | 0.01 | 0.98 | FALSE |
| 6 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | AGT | 0.11 | 0.05 | blup | 125 | 0.04 | 1.4e-03 | 9.66 | 9.3 | 1.2e-20 | 0.70 | 0.02 | 0.85 | FALSE |
| 7 | The Cancer Genome Atlas | Stomach Adenocarcinoma | CAPN9 | 0.08 | 0.00 | blup | 158 | 0.04 | 7.1e-04 | -0.41 | 5.5 | 4.8e-08 | 0.41 | 0.06 | 0.18 | FALSE |