[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr1:226,488,826-229,344,237

Best TWAS P=6.63e-15 · Best GWAS P=3.19e-20 conditioned to 6.42e-08

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	OBSCN	0.14	0.15	enet	15	0.18	7.2e-21	-6.7	5.7	1.6e-08	-0.57	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	RP5-1139B12.2	0.08	0.02	enet	17	0.03	2.2e-03	-2.8	-5.4	6.7e-08	0.66	0.18	0.19	FALSE
3	GTEx	Artery Tibial	RP5-1139B12.2	0.09	0.05	lasso	5	0.05	4.5e-05	-5.8	-5.5	3.7e-08	0.76	0.37	0.60	FALSE
4	GTEx	Brain Cortex	OBSCN	0.26	0.04	lasso	10	0.12	4.5e-04	2.5	5.3	1.1e-07	-0.24	0.09	0.05	FALSE
5	GTEx	Cells Transformed fibroblasts	OBSCN	0.28	0.35	lasso	9	0.37	2.0e-29	-6.8	6.9	4.9e-12	-0.71	1.00	0.00	FALSE
6	GTEx	Cells Transformed fibroblasts	RP5-1139B12.2	0.29	0.32	enet	25	0.35	2.3e-27	-6.8	7.7	1.1e-14	-0.77	1.00	0.00	FALSE
7	GTEx	Cells Transformed fibroblasts	RP5-1139B12.3	0.28	0.31	lasso	10	0.33	8.4e-26	-6.8	7.5	9.5e-14	-0.72	1.00	0.00	FALSE
8	GTEx	Colon Sigmoid	IBA57	0.17	0.20	lasso	1	0.19	2.4e-07	-6.1	-6.1	8.5e-10	0.67	0.90	0.02	FALSE
9	GTEx	Esophagus Mucosa	SNAP47	0.17	0.02	enet	43	0.08	5.2e-06	3.0	7.1	1.1e-12	-0.26	0.59	0.17	FALSE
10	GTEx	Esophagus Mucosa	OBSCN	0.30	0.37	lasso	5	0.37	5.1e-26	-6.8	-6.9	6.5e-12	0.71	1.00	0.00	FALSE
11	GTEx	Esophagus Mucosa	RP5-1139B12.2	0.08	0.04	lasso	3	0.03	2.6e-03	-6.1	-6.4	1.3e-10	0.69	0.20	0.60	FALSE
12	GTEx	Esophagus Muscularis	MRPL55	0.06	0.05	lasso	3	0.04	2.2e-03	-6.7	6.9	5.1e-12	-0.76	0.27	0.32	FALSE
13	GTEx	Lung	IBA57	0.06	0.08	lasso	1	0.06	2.0e-05	-6.2	-6.2	7.0e-10	0.67	0.94	0.01	FALSE
14	GTEx	Muscle Skeletal	CDC42BPA	0.12	0.06	enet	28	0.11	8.2e-11	-2.0	-5.3	1.2e-07	0.05	0.04	0.96	FALSE
15	GTEx	Muscle Skeletal	RP5-1087E8.3	0.06	0.05	lasso	4	0.06	1.4e-06	5.9	-5.6	1.9e-08	0.01	0.02	0.98	TRUE
16	GTEx	Nerve Tibial	SNAP47	0.06	0.01	enet	16	0.03	6.5e-03	-3.0	7.0	2.9e-12	-0.45	0.10	0.71	FALSE
17	GTEx	Nerve Tibial	MRPL55	0.08	0.06	enet	10	0.03	2.4e-03	-5.1	6.2	7.1e-10	-0.75	0.64	0.29	FALSE
18	GTEx	Skin Not Sun Exposed Suprapubic	OBSCN	0.41	0.31	lasso	8	0.28	5.9e-16	-6.9	-7.0	3.5e-12	0.72	1.00	0.00	FALSE
19	GTEx	Skin Not Sun Exposed Suprapubic	RP5-1139B12.2	0.18	0.12	lasso	4	0.12	2.3e-07	-6.9	-7.0	1.9e-12	0.74	0.99	0.00	FALSE
20	GTEx	Skin Sun Exposed Lower leg	OBSCN	0.38	0.21	lasso	6	0.25	1.8e-20	-6.1	-6.8	1.2e-11	0.73	1.00	0.00	FALSE
21	GTEx	Skin Sun Exposed Lower leg	HIST3H2A	0.05	0.03	lasso	4	0.03	2.4e-03	-6.7	-6.7	2.6e-11	0.69	0.09	0.82	FALSE
22	GTEx	Skin Sun Exposed Lower leg	RP5-1139B12.2	0.07	0.04	enet	8	0.04	3.9e-04	-6.1	-6.4	1.4e-10	0.64	0.88	0.02	FALSE
23	GTEx	Testis	SNAP47	0.23	0.21	enet	15	0.21	7.5e-10	-4.8	5.6	1.8e-08	-0.13	1.00	0.00	FALSE
24	GTEx	Thyroid	MRPL55	0.07	0.02	lasso	3	0.03	4.2e-03	-6.1	5.2	2.0e-07	-0.53	0.18	0.14	FALSE
25	GTEx	Whole Blood	IBA57	0.07	0.02	enet	12	0.03	3.8e-04	-6.9	-7.8	6.6e-15	0.64	0.19	0.71	TRUE
26	NTR	Blood	HIST3H3	0.01	0.00	bslmm	359	0.01	3.5e-03	1.6	5.4	6.8e-08	-0.45	0.18	0.12	FALSE
27	YFS	Blood	OBSCN	0.03	0.03	lasso	3	0.03	3.7e-10	-6.1	-6.2	5.3e-10	0.73	1.00	0.00	FALSE
28	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	OBSCN	0.07	0.09	blup	96	0.10	2.8e-11	-6.8	-6.7	2.7e-11	0.71	0.02	0.98	FALSE
29	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C1orf69	0.05	0.02	blup	30	0.03	7.3e-03	-6.9	7.4	1.5e-13	-0.74	0.01	0.77	FALSE
30	The Cancer Genome Atlas	Brain Lower Grade Glioma	MRPL55	0.04	0.06	lasso	1	0.06	2.4e-07	-5.2	5.2	2.2e-07	-0.65	0.14	0.84	FALSE
31	The Cancer Genome Atlas	Brain Lower Grade Glioma	SNAP47	0.08	0.06	blup	54	0.08	1.2e-09	-4.8	6.1	9.9e-10	-0.03	0.03	0.96	FALSE
32	The Cancer Genome Atlas	Lung Adenocarcinoma	ARF1	0.04	0.02	lasso	2	0.01	1.3e-02	-5.0	5.3	9.1e-08	-0.72	0.03	0.19	FALSE
33	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	OBSCN	0.08	0.06	lasso	3	0.06	2.7e-07	-6.7	-7.0	2.3e-12	0.70	0.03	0.97	FALSE