Best TWAS P=1.13e-10 · Best GWAS P=1.07e-08 conditioned to 0.175
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Spleen | CYP2D7P1 | 0.17 | 0.0 | lasso | 3 | 0.03 | 0.04780 | 5.7 | 6.4 | 1.1e-10 | 0.75 | 0.01 | 0.86 | TRUE |
2 | GTEx | Stomach | CYP2D7P1 | 0.22 | 0.1 | lasso | 14 | 0.07 | 0.00027 | -3.0 | 5.3 | 1.4e-07 | 0.35 | 0.20 | 0.60 | FALSE |