Best TWAS P=2.41e-10 · Best GWAS P=4.33e-08 conditioned to 0.951
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SGSM3 | 0.02 | 0.01 | lasso | 2 | 0.01 | 1.9e-03 | 5.2 | 5.6 | 1.6e-08 | 0.55 | 0.03 | 0.37 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SGSM3 | 0.07 | 0.02 | blup | 43 | 0.03 | 1.1e-02 | 5.2 | 6.3 | 2.4e-10 | 0.87 | 0.01 | 0.71 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TNRC6B | 0.05 | 0.03 | lasso | 8 | 0.04 | 6.9e-06 | 5.4 | 5.9 | 4.6e-09 | 0.94 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | ADSL | 0.06 | 0.01 | blup | 33 | 0.03 | 1.1e-02 | 5.4 | 5.5 | 3.1e-08 | 0.96 | 0.01 | 0.84 | FALSE |
| 5 | The Cancer Genome Atlas | Stomach Adenocarcinoma | ADSL | 0.04 | 0.00 | blup | 33 | 0.03 | 2.6e-03 | 5.4 | 5.5 | 3.4e-08 | 0.88 | 0.02 | 0.78 | FALSE |