TWAS hub - CYP2D7P1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.099	0.0500	7.5e-03	0.004	NA	0.026	NA	0.001	1.5e-01	NA	3.2e-03	NA	2.8e-01
2	GTEx	Adipose Visceral Omentum	0.169	0.0650	2.0e-03	0.002	NA	0.009	NA	0.019	2.3e-01	NA	1.1e-01	NA	3.4e-02
3	GTEx	Brain Cerebellar Hemisphere	0.394	0.1000	2.0e-05	0.086	NA	0.201	NA	0.191	3.3e-03	NA	7.2e-06	NA	1.2e-05
4	GTEx	Brain Cerebellum	0.370	0.0910	6.4e-07	0.230	NA	0.159	NA	0.207	2.1e-07	NA	1.9e-05	NA	9.2e-07
5	GTEx	Breast Mammary Tissue	0.252	0.0700	5.0e-05	0.052	NA	0.022	NA	0.030	1.2e-03	NA	2.6e-02	NA	1.1e-02
6	GTEx	Breast Mammary Tissue (Male)	0.322	0.1090	7.5e-03	-0.005	NA	0.000	NA	0.023	4.3e-01	NA	3.2e-01	NA	9.7e-02
7	GTEx	Breast Mammary Tissue (Female)	0.208	0.0930	1.1e-02	0.004	NA	-0.006	NA	0.006	2.4e-01	NA	5.5e-01	NA	2.1e-01
8	GTEx	Colon Transverse	0.127	0.0500	2.5e-04	0.108	NA	0.072	NA	0.091	8.1e-06	NA	2.6e-04	NA	4.1e-05
9	GTEx	Esophagus Mucosa	0.231	0.0680	5.8e-06	0.092	NA	0.074	NA	0.092	1.0e-06	NA	1.2e-05	NA	9.5e-07
10	GTEx	Lung	0.197	0.0775	1.7e-03	-0.002	NA	-0.002	NA	-0.001	4.8e-01	NA	5.1e-01	NA	4.2e-01
11	GTEx	Pituitary	0.353	0.1010	2.0e-04	0.163	NA	0.145	NA	0.163	6.8e-05	NA	1.7e-04	NA	6.9e-05
12	GTEx	Prostate	0.254	0.1160	7.7e-03	-0.002	NA	0.067	NA	0.040	3.7e-01	NA	9.2e-03	NA	3.5e-02
13	GTEx	Skin Sun Exposed Lower leg	0.084	0.0350	3.5e-04	0.042	NA	0.070	NA	0.056	2.2e-04	NA	2.0e-06	NA	2.0e-05
14	GTEx	Spleen	0.169	0.0930	9.3e-03	0.003	NA	0.018	NA	0.034	2.6e-01	NA	1.1e-01	NA	4.8e-02
15	GTEx	Stomach	0.217	0.0790	1.2e-04	0.102	NA	0.065	NA	0.071	1.4e-05	NA	4.6e-04	NA	2.7e-04
16	GTEx	Thyroid	0.359	0.0690	6.2e-13	0.166	NA	0.206	NA	0.177	1.0e-12	NA	1.1e-15	NA	1.6e-13
17	GTEx	Whole Blood	0.103	0.0410	3.1e-04	0.021	NA	0.042	NA	0.026	4.4e-03	NA	8.4e-05	NA	1.9e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Schizophrenia (2018)	8.1	16.9	32.6	4.0	2.5	0.2	1.3	4.6	4.1	3.7	5.0	4.5	5.6	2.5	5.0	4.5	4.9	5.7	4.5	2.3
Schizophrenia (2014)	7.9	17.6	37.0	4.4	1.5	-0.7	0.7	4.5	4.8	3.2	4.9	4.2	6.1	2.0	5.4	4.3	5.4	5.9	4.1	3.3
Bipolar Disorder or Schizophrenia	6.2	15.0	31.1	3.7	1.3	-0.6	0.1	4.6	3.6	3.7	4.9	4.1	5.2	1.5	4.7	3.4	5.2	5.6	4.2	3.7
Friendships satisfaction	4.2	5.2	13.4	1.9	-0.5	1.0	0.8	1.4	1.9	1.5	2.9	2.9	3.1	1.7	3.1	3.7	2.3	3.3	1.7	2.3
Mouth/teeth dental problems: Loose teeth	3.9	4.6	9.9	-1.1	0.2	2.0	2.6	1.6	1.4	0.8	2.9	3.1	1.9	2.8	2.3	3.1	1.8	2.1	2.8	1.2
Alzheimer’s Disease (in mother)	3.2	3.7	15.5	-0.1	1.2	3.3	3.5	-0.3	0.9	-0.4	1.5	1.9	1.1	3.9	2.3	2.5	0.4	0.9	1.3	-0.6
Alzheimer’s Disease (in father)	3.0	3.2	9.0	3.0	1.7	1.5	2.3	1.4	3.0	-0.3	1.1	1.5	1.6	2.1	2.0	0.6	1.5	1.6	1.6	1.5
Happiness	3.0	3.6	7.3	0.9	-1.0	0.7	0.7	1.9	1.1	2.1	2.2	2.1	2.7	1.5	1.7	2.4	1.7	2.6	2.4	2.7
Nervous feelings	2.9	5.3	13.5	1.7	3.3	3.7	3.0	2.4	0.9	2.5	1.8	3.0	-0.1	2.5	1.3	3.6	1.2	1.1	2.4	-0.5
Alzheimer’s Disease (including proxy)	2.7	3.8	9.1	2.7	1.6	2.7	2.9	0.0	2.3	-1.0	1.2	1.7	2.0	3.0	2.7	1.6	1.1	1.6	1.5	0.6
Average weekly spirits intake	2.6	3.3	9.1	0.6	-0.8	-0.5	-0.1	-0.5	0.7	-1.1	-3.0	-2.7	-2.1	-1.1	-1.3	-2.0	-2.9	-3.0	-2.5	-1.0
Diabetes (mother)	2.6	3.3	7.3	0.9	0.4	1.3	1.6	1.5	1.5	1.0	2.3	2.0	1.9	2.2	2.7	2.3	2.1	2.3	2.1	0.6
Schizophrenia vs Biploar Disorder	2.5	3.3	9.6	1.4	2.3	-0.0	1.3	2.1	1.9	1.2	1.8	2.2	2.3	1.4	1.1	3.1	1.4	1.9	2.3	-0.3
Systolic Blood Pressure	2.5	12.3	41.6	4.7	3.2	1.1	1.4	3.0	2.7	1.9	2.9	3.2	4.5	2.2	3.6	3.3	6.4	5.3	3.5	1.9
Ever used hormone-replacement therapy (HRT)	2.5	3.1	13.9	-0.3	-2.7	-3.7	-3.0	0.1	-0.1	-0.5	-1.0	-2.0	0.3	-2.5	0.5	-2.0	-1.2	-0.6	-1.8	1.4
Eye problems/disorders: Cataract	2.4	2.7	8.4	0.1	-1.6	0.7	-0.0	-1.0	-2.3	-1.3	-2.4	-2.6	-2.1	0.3	-1.5	-2.9	-1.3	-1.9	-1.6	-0.4
Guilty feelings	2.4	3.5	10.9	1.1	0.7	0.6	0.4	2.2	-1.2	2.9	2.4	2.3	1.7	1.0	-0.2	2.2	2.4	2.6	3.3	-0.2
Depression (Nagel 2018)	2.3	3.4	7.3	2.4	-1.7	-0.6	-0.1	1.6	1.2	1.0	2.7	2.1	2.5	1.1	2.4	2.1	1.2	2.5	1.4	2.2
Worry too long after embarrassment	2.2	3.8	11.6	2.7	1.5	2.5	1.8	2.5	0.9	1.9	1.9	2.6	1.3	1.0	1.5	3.4	0.5	1.1	2.2	0.5
Number of full sisters	2.2	2.6	9.9	1.5	-0.0	0.6	0.7	0.5	3.1	-0.4	1.3	1.3	2.1	0.6	2.9	1.5	0.5	1.2	0.8	3.2
Chest pain or discomfort	2.2	3.1	11.1	3.3	-1.0	0.4	-0.3	2.0	0.1	1.6	2.1	1.7	1.6	0.3	1.8	1.8	2.4	2.2	2.0	1.7
Verbal and Numeric Reasoning (VNR)	2.1	5.1	16.6	-4.1	-1.5	2.7	1.8	-0.1	0.2	-0.1	-2.9	-2.5	-3.6	0.8	-2.2	-1.7	-1.6	-3.2	-1.6	-2.4
Breast cancer (self-reported)	2.1	2.5	8.6	-1.3	0.5	1.8	0.8	0.6	-1.0	0.4	-2.1	-1.3	-2.9	-0.7	-1.2	-1.6	-2.2	-2.6	-1.5	-1.3
Mother’s age at death	2.1	2.6	7.2	-2.1	-0.7	0.8	-0.4	0.1	0.0	0.6	-2.4	-2.3	-1.9	-1.2	-0.7	-1.5	-2.3	-2.5	-2.7	-0.5
Unable to work because of sickness or disability	2.1	2.7	6.4	1.8	-0.8	1.1	0.7	1.0	1.1	0.5	2.4	2.0	2.1	0.9	2.4	1.0	2.1	2.5	1.7	1.6
Severe depression (siblings)	2.0	2.2	5.9	1.7	-0.3	0.2	0.6	1.2	-0.2	0.8	2.2	1.9	1.6	1.2	0.2	1.9	2.1	2.2	2.4	0.8
Stomach or abdominal pain in last month	2.0	2.5	7.6	1.4	-0.8	-0.8	-0.0	1.2	1.6	0.8	2.8	2.1	1.8	0.8	1.1	1.4	1.5	2.0	2.3	2.2
Had menopause	2.0	2.5	7.8	-0.9	-0.6	-1.5	-0.6	-1.4	-0.2	-1.4	-2.6	-2.5	-1.2	-0.9	-0.2	-2.0	-1.8	-2.0	-2.8	-1.3
Chronic bronchitis/emphysema (mother)	2.0	2.4	5.2	-0.9	-2.1	-1.3	-2.1	-0.8	-1.0	-0.7	-1.3	-1.8	-1.5	-2.3	-1.1	-2.3	-1.6	-1.5	-1.4	1.2
Health satisfaction	2.0	2.6	5.4	1.5	-2.0	1.6	0.6	0.6	0.8	0.0	1.9	2.0	2.1	0.3	2.3	2.0	1.3	1.9	1.3	2.2
Qualifications: nursing, teaching	2.0	3.1	8.8	-0.1	0.2	-0.7	-0.5	-0.9	-1.2	-1.0	-2.6	-3.0	-2.4	-0.3	-2.9	-2.7	-0.8	-2.1	-1.2	-2.2
Wears glasses or contact lenses	2.0	2.3	5.4	-1.0	-1.5	-1.7	-1.5	0.2	-1.4	0.5	-1.3	-1.9	-1.4	-1.6	-2.1	-2.3	-2.1	-1.5	-1.1	-0.6
Bipolar Disorder (2011)	1.9	1.8	9.7	1.2	-1.4	-1.4	-1.7	0.5	0.9	0.8	0.4	-0.3	1.6	-1.0	2.3	-0.4	0.0	1.0	-1.0	3.1
Hand grip strength (left)	1.9	4.9	23.9	1.4	-1.9	-4.9	-4.0	1.1	1.2	0.7	1.4	-0.3	2.8	-2.7	-0.6	-1.5	1.3	2.0	0.7	3.0
Pain type(s) experienced in last month: Hip pain	1.9	2.4	5.6	1.6	-1.3	1.3	0.8	1.4	0.9	0.9	1.6	1.0	2.0	1.7	2.3	0.6	1.8	1.7	1.6	2.4
Myopia	1.9	2.7	8.3	-1.6	2.1	2.9	2.6	-0.4	2.4	-0.7	0.2	0.5	-1.2	1.4	-1.7	0.4	-2.0	-1.9	1.3	-1.1
Body Mass Index (BMI) (2010)	1.8	2.4	10.4	1.9	-1.4	-2.6	-3.2	-1.1	-1.4	-0.1	-0.3	-1.5	0.7	-1.9	-0.1	-2.1	1.0	0.7	-0.8	1.5
Had other major operations	1.8	2.1	7.0	-0.4	-1.1	2.1	1.3	-0.5	-1.2	-1.2	-1.6	-0.7	-2.4	-0.3	0.4	-0.3	-2.6	-2.7	-1.3	-1.1
Pulse wave reflection index	1.8	2.2	5.7	1.2	-1.3	-1.7	-2.2	-1.5	-1.1	-1.2	-1.6	-1.7	0.2	-2.4	-1.9	-1.1	-1.1	-1.0	-1.5	0.5
Blood clot in the leg (DVT)	1.8	2.3	10.0	0.6	-3.2	-0.8	-2.0	-1.7	-1.9	-1.5	-1.1	-1.7	0.4	-1.8	-1.2	-2.2	-0.2	-0.2	-1.6	0.5
Medication: Paracetamol	1.8	2.9	8.0	2.3	-2.8	-2.2	-1.4	0.8	0.2	-0.1	1.5	0.1	2.7	0.5	0.6	-1.1	1.8	2.5	0.7	2.8
Mean time to correctly identify matches	1.8	3.4	10.4	-2.4	3.1	3.1	3.2	0.7	2.2	0.9	-0.3	0.8	-1.9	1.6	-0.0	1.3	-1.5	-1.7	0.1	-1.5
Commuting to job workplace: Public transport	1.8	2.1	7.4	-1.0	0.0	1.7	2.1	2.7	1.3	2.2	1.1	1.2	-0.1	1.8	0.2	1.7	-0.7	-0.1	1.3	-1.5
Age started oral contraceptive pill	1.8	2.3	5.7	-2.4	0.3	0.8	1.5	-1.4	-2.0	-0.9	-1.9	-0.8	-1.3	1.1	-0.8	-0.2	-2.3	-1.6	-2.1	-1.8
Blood White Count	1.7	12.9	31.7	1.8	0.8	0.9	2.3	3.3	-0.3	2.7	5.3	5.6	4.4	3.5	3.3	5.3	3.8	5.3	4.2	0.6
Chronotype (morning person)	1.7	3.8	17.0	-0.4	1.6	-3.3	-4.1	-2.0	-1.9	0.0	-0.6	-0.9	0.8	-3.5	-2.1	-0.7	2.5	1.3	-0.4	0.2
Systolic blood pressure, automated reading	1.7	5.1	18.1	3.0	1.2	-0.5	-0.1	0.7	1.3	-0.2	1.9	1.8	3.9	0.9	2.6	1.9	4.2	3.8	2.2	1.7
Eye problems/disorders: Diabetes related eye disease	1.7	1.9	9.1	0.2	-3.0	-2.0	-2.1	-0.8	-1.8	-0.5	-0.8	-1.4	0.2	-1.2	-0.3	-1.6	0.1	0.2	-1.5	1.3
Hair/balding pattern: Pattern 2	1.7	2.1	6.4	0.7	0.3	-1.6	-0.3	0.6	1.2	0.2	2.1	1.8	2.5	0.7	1.1	1.3	1.9	2.5	1.6	1.0
Pulse wave Arterial Stiffness index	1.7	1.9	5.8	2.1	-2.4	-1.5	-2.1	-0.5	-0.3	-0.4	-1.2	-1.6	1.4	-1.9	-1.8	-0.7	0.5	0.3	-0.7	1.2
Eye problems/disorders: None of the above	1.7	1.9	7.0	0.0	1.5	-0.3	0.0	1.0	2.6	1.0	1.9	1.8	1.5	-0.2	1.7	2.3	0.8	1.1	1.3	0.6
Migraine (self-reported)	1.7	2.1	8.6	0.8	-2.9	-1.5	-1.0	2.3	-0.0	1.8	-0.0	-0.8	1.4	0.3	2.5	-0.6	0.3	0.6	-0.5	2.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.7	2.1	5.4	-0.2	2.3	0.1	1.3	0.3	1.3	0.1	1.6	2.2	1.4	1.2	0.8	2.3	2.2	1.6	1.6	0.1
Intelligence (Savage-Jansen 2018)	1.6	5.0	18.9	-4.3	-1.3	2.6	2.4	1.3	-0.5	1.2	-1.8	-1.9	-3.6	2.4	-1.4	-1.5	-1.6	-2.8	-1.3	-2.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.1	6.0	2.4	-1.3	0.1	0.0	1.6	-0.5	1.3	2.4	2.0	1.4	1.1	1.3	1.7	0.7	2.0	1.2	0.6
Chronic bronchitis/emphysema (father)	1.6	1.9	6.5	1.2	-1.7	-1.8	-2.3	-0.7	1.1	-1.3	-0.3	-0.7	0.8	-2.4	1.4	-0.8	-0.3	0.0	-0.5	2.5
Pulse wave peak to peak time	1.6	1.8	5.6	-1.8	2.4	1.4	2.1	0.7	0.4	0.6	1.2	1.7	-1.2	1.9	1.8	0.8	-0.3	-0.1	0.7	-1.1
Family relationship satisfaction	1.6	2.0	5.1	1.1	-1.6	0.7	-0.0	1.4	0.4	1.5	1.6	1.5	2.0	0.5	0.8	2.1	1.7	2.3	1.1	1.6
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	7.3	-2.0	0.2	0.2	0.3	0.1	-1.8	0.2	-0.0	0.3	-2.5	-0.2	-1.5	0.2	-2.7	-1.6	-0.3	-1.8
Medication: Paracetamol	1.6	2.4	5.7	1.4	-2.1	-2.2	-1.5	1.7	0.2	1.4	1.5	0.2	2.3	0.1	0.6	-0.4	1.9	2.3	0.6	2.4
Smoking Status	1.5	3.6	11.3	0.9	-1.7	2.3	3.2	2.5	1.9	0.4	0.3	0.8	-1.3	2.6	3.4	0.3	-2.6	-1.5	-1.2	1.3
Average weekly fortified wine intake	1.5	1.7	6.6	-0.2	2.1	1.7	2.2	-0.4	-0.2	0.1	-0.5	0.1	-1.0	1.7	-1.9	0.3	-0.7	-0.9	1.1	-2.6
Birth weight of first child	1.5	2.8	10.8	0.6	-2.1	-2.5	-3.3	0.7	-2.3	1.3	0.2	-0.8	0.8	-2.5	-1.3	-1.9	0.8	1.1	-0.7	1.8
Illnesses of father: None of the above (group 1)	1.5	1.9	4.5	-1.4	0.1	1.2	1.4	0.3	-1.7	-0.3	-1.4	-1.1	-2.1	1.5	-1.5	-1.3	-1.0	-1.7	-2.0	-1.2
Bipolar Disorder (2018)	1.4	2.2	8.9	1.1	-1.3	-1.3	-1.6	1.8	0.6	1.6	1.6	0.6	1.3	-0.6	1.1	-0.4	2.1	1.8	1.1	3.0
Reaction Time	1.4	2.6	8.4	-0.7	2.9	2.6	2.7	1.1	2.2	1.7	0.5	1.4	-0.6	1.6	0.2	2.1	-0.5	-0.4	0.9	-1.0
BMI	1.4	8.0	34.2	-1.5	-2.0	-5.1	-4.3	-4.5	-5.9	-2.7	-0.5	-1.6	0.7	-2.3	-0.9	-2.9	1.2	0.7	-1.7	-1.1
Hand grip strength (right)	1.4	3.7	15.4	1.6	-0.5	-3.9	-2.7	0.7	2.0	0.3	1.6	0.3	2.8	-1.4	0.1	-0.5	2.3	2.5	1.5	2.7
Qualifications: A levels/AS levels or equivalent	1.4	3.1	13.0	-3.6	1.9	3.1	2.8	0.2	1.0	1.0	-0.3	0.1	-1.7	2.0	-1.0	0.7	-0.4	-1.1	0.9	-2.4
Loud music exposure frequency	1.4	1.5	4.5	-1.3	0.5	1.8	1.4	-0.4	0.8	-0.2	1.4	1.8	-0.0	1.4	2.0	2.1	-0.5	0.3	0.5	0.7
Birth weight	1.4	3.1	12.4	-0.1	-3.2	-3.5	-3.2	0.5	-0.2	-0.1	0.1	-1.5	0.5	-2.1	0.3	-2.5	0.1	0.5	-1.0	2.1
Medication for pain relief, constipation, heartburn	1.4	2.4	12.0	-2.3	2.7	1.4	2.2	-0.4	-0.5	0.3	-1.0	0.1	-1.7	1.3	-0.4	1.1	0.0	-1.1	0.7	-3.5
Commuting to job workplace: Car/motor vehicle	1.4	1.6	5.8	2.4	0.6	-0.3	-0.9	-0.3	1.3	-0.5	0.8	0.5	1.4	-0.4	1.6	0.2	2.2	1.7	0.8	1.8
Average weekly red wine intake	1.4	2.1	4.8	0.2	-1.8	-1.6	-1.3	-0.5	-0.2	-0.9	-1.7	-2.2	-1.1	-1.5	-2.2	-2.1	-1.7	-1.7	-1.3	-0.3
Smoking status: Current	1.4	2.2	13.8	1.1	-1.0	0.4	1.6	2.4	1.8	1.0	0.7	0.5	-0.1	1.7	3.7	0.2	-1.4	-0.3	-1.7	0.8
Diastolic blood pressure, automated reading	1.4	4.3	19.6	1.7	-0.2	-1.7	-1.6	0.8	-1.1	1.2	2.2	1.3	3.3	0.5	1.7	0.9	4.4	4.0	2.0	0.6
Supplements: Glucosamine	1.3	1.7	6.5	-0.8	-0.0	1.1	0.9	-0.5	-1.1	-0.6	-1.7	-0.8	-2.4	-0.2	-0.6	-0.5	-2.5	-2.6	-1.3	-0.8
Medication: Levothyroxine sodium	1.3	2.2	10.7	1.0	0.7	2.3	1.6	-0.1	3.3	0.2	0.5	0.7	1.7	1.2	2.3	1.4	1.3	0.8	0.8	1.4
Number of incorrect matches in round	1.3	2.1	8.5	-0.1	-0.1	-2.5	-2.9	-2.1	-2.0	-1.3	-0.3	-0.7	0.5	-2.8	-1.1	-0.9	-0.2	-0.2	-0.3	-0.1
Hayfever/allergic rhinitis (self-reported)	1.3	1.7	9.8	3.1	0.1	1.8	0.3	1.7	-1.0	2.0	1.0	1.1	0.1	0.7	0.5	1.2	0.6	1.1	1.3	0.2
Headache pain in last month	1.3	2.2	12.2	2.4	-3.5	-1.1	-1.7	0.8	-0.8	-0.1	0.4	-0.4	1.3	-0.5	1.5	-0.9	0.8	1.3	-0.2	2.6
Arm fat-free mass (right)	1.3	6.6	28.5	1.0	-2.7	-5.3	-4.8	-2.4	-2.2	-1.6	0.3	-1.6	2.2	-2.7	-0.6	-2.8	2.7	2.3	-0.5	1.9
Shortness of breath walking on level ground	1.3	1.5	3.2	0.8	-0.7	1.2	0.8	-0.3	0.7	-0.5	1.5	1.5	1.8	1.2	1.1	1.7	1.4	1.5	1.7	1.1
Qualifications: College or University degree	1.3	4.1	14.6	-1.6	1.2	3.8	3.1	2.3	0.6	2.5	-1.3	-0.8	-3.0	2.3	-2.0	0.1	-1.1	-2.1	0.6	-1.8
Medication: Seretide 50 evohaler	1.3	1.5	5.4	-1.5	2.3	1.4	0.6	-1.3	-0.6	-0.8	1.4	2.0	0.1	-0.0	-0.4	1.8	0.7	0.9	1.0	-0.9
Overall health rating	1.3	2.7	7.7	1.2	-0.5	0.9	0.3	-0.3	-1.0	-0.1	2.3	2.6	2.0	0.3	1.9	2.1	2.8	2.7	1.6	1.1
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.5	4.7	2.2	-0.0	-1.0	-1.2	-0.5	0.9	-0.3	0.4	0.4	1.6	-1.5	1.9	-0.2	1.8	1.4	1.2	1.4
Osteoarthritis (self-reported)	1.3	1.7	9.0	0.1	-1.2	1.2	0.3	-2.8	-1.2	-3.0	-1.4	-0.9	-0.6	0.1	1.3	-0.7	0.2	-0.6	-1.4	-0.4
Pain experienced in last month	1.3	2.2	15.5	-1.8	3.9	0.3	1.5	-0.5	-0.5	0.4	-0.1	0.9	-0.2	1.1	-1.3	1.7	0.1	-0.2	0.8	-2.9
Worry (Nagel 2018)	1.2	2.4	6.7	1.4	2.3	0.9	0.3	1.6	-0.9	1.8	1.8	2.5	0.9	0.4	0.2	2.6	1.6	1.8	1.9	-0.1
Blood Eosinophil Count	1.2	9.2	20.9	-1.2	1.0	1.8	1.9	0.1	-1.9	1.3	4.1	4.0	3.1	3.6	0.8	4.6	3.9	4.2	4.4	-3.6
Pack years adult smoking proportion	1.2	1.8	6.0	0.7	-0.5	0.4	1.4	0.8	1.6	-0.3	1.4	1.0	1.1	2.3	2.4	0.3	1.3	1.6	0.6	2.3
Current tobacco smoking	1.2	2.0	12.0	0.6	-1.0	0.1	1.4	2.4	1.9	0.8	0.5	0.4	-0.2	1.3	3.5	0.1	-1.6	-0.5	-1.8	0.7
Age when periods started (menarche)	1.2	2.8	7.0	0.8	0.2	2.3	2.5	1.1	2.6	0.5	1.5	1.4	1.5	2.3	0.9	1.5	2.0	1.3	2.4	0.7
Past tobacco smoking	1.2	2.2	11.1	0.2	-0.8	-3.3	-3.1	-1.0	-0.5	-0.1	-0.0	-1.0	1.6	-1.8	-0.8	-1.3	1.4	1.4	-1.1	0.5
Alcohol usually taken with meals	1.2	2.0	10.3	-0.9	-0.6	-3.2	-2.5	-0.5	-0.0	-0.2	-0.8	-1.8	-0.3	-1.8	-1.9	-1.8	-0.6	-0.6	-0.8	0.7
Noisy workplace	1.2	1.5	7.0	0.9	-2.6	-0.6	-1.8	-1.0	-0.3	-1.1	0.6	0.1	1.1	-1.7	0.3	-0.6	-0.4	0.5	-0.6	2.5
Medication: Lansoprazole	1.2	1.3	5.1	0.8	-0.3	0.3	0.7	1.1	0.5	0.6	0.7	0.5	1.7	1.7	1.3	0.7	2.3	1.9	-0.1	1.4
Prospective memory result	1.2	1.5	11.5	-0.7	0.1	-0.4	-0.7	-3.4	-1.5	-2.7	-0.9	-0.8	-0.2	-0.2	-0.3	-0.8	-0.2	-0.4	-0.2	0.5
Exposure to tobacco smoke outside home	1.2	1.6	5.4	0.1	1.5	2.2	2.0	-0.7	1.2	-0.7	0.6	1.4	-0.0	1.5	2.3	1.8	-0.6	0.1	0.4	0.5
Arm predicted mass (right)	1.2	6.0	25.9	1.3	-2.5	-5.1	-4.6	-1.9	-1.8	-1.4	0.9	-1.0	2.5	-2.5	-0.3	-2.2	2.8	2.7	0.1	2.1
Hearing aid user	1.2	1.3	3.4	0.1	-0.2	-1.7	-1.7	0.2	-1.8	0.6	-1.2	-1.3	-0.7	-1.4	-0.1	-1.2	-1.2	-0.7	-1.9	-1.0
Ever smoked	1.2	2.2	8.7	-0.7	0.5	2.7	2.9	1.3	0.4	0.2	0.0	0.8	-2.0	1.8	0.9	1.0	-2.0	-1.9	0.4	-0.9
Average weekly beer plus cider intake	1.2	1.7	13.0	0.4	-0.9	2.2	1.0	1.3	1.5	0.9	0.8	0.7	0.9	1.1	3.6	1.0	0.2	0.7	-0.2	0.6
Fractured/broken bones in last 5 years	1.2	1.5	4.1	1.1	-1.3	-1.4	-2.0	-1.1	-0.6	-0.8	-1.4	-1.9	0.2	-1.9	-0.6	-1.8	-0.1	-0.6	-0.9	0.8
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	8.9	0.9	-3.0	-0.6	-1.7	-1.0	-1.3	-0.8	-0.6	-1.2	1.1	-1.4	-0.6	-1.6	0.1	0.4	-1.1	0.7
Frequency of depressed mood in last 2 weeks	1.1	1.6	6.1	1.4	-1.3	0.2	0.2	1.2	0.8	1.0	1.7	1.2	1.3	1.1	0.9	0.9	0.9	1.5	1.4	2.5
Maternal smoking around birth	1.1	1.6	5.2	1.5	-1.0	-1.4	-0.0	2.0	1.4	0.7	1.4	1.3	1.2	-0.2	1.8	0.7	-1.4	0.2	0.2	2.3
Comparative body size at age 10	1.1	3.0	15.8	-0.6	1.1	-4.0	-2.4	-0.3	-2.0	0.2	2.4	1.1	2.4	-0.9	-0.5	-0.8	1.8	2.3	0.9	-0.1
Neck or shoulder pain in last month	1.1	1.6	14.0	0.8	-3.7	-0.1	-0.7	0.6	0.8	-0.7	0.4	-0.3	0.1	-0.5	0.3	-1.0	-0.6	-0.1	0.5	2.9
Illness, injury, bereavement, stress in last 2 years	1.1	1.3	7.9	-1.1	1.5	0.1	0.9	0.2	-1.2	0.4	-1.0	-0.2	-1.3	-0.0	-2.8	-0.1	-0.8	-1.4	-0.3	-1.9
Osteoporosis (self-reported)	1.1	1.4	4.3	0.7	-0.2	-2.1	-2.1	0.7	-0.4	0.9	0.7	0.2	1.9	-1.5	-0.6	-0.4	1.6	1.6	0.7	1.0
Rheumatoid Arthritis	1.0	1.3	4.5	-2.1	1.4	1.4	2.0	-1.2	0.7	-1.4	-0.2	0.7	-0.3	1.6	1.4	0.8	-0.0	-0.3	-0.1	-0.6
Number of treatments/medications taken	1.0	1.8	5.7	2.3	-2.4	-1.0	-2.3	-0.2	-1.1	-0.3	-0.6	-1.2	0.8	-2.3	-0.3	-0.8	-0.3	-0.1	-1.5	0.4
Tinnitus: Yes, but not now, but have in the past	1.0	1.0	2.2	1.1	-0.7	0.7	0.3	1.1	-0.2	1.4	1.5	1.2	1.3	0.2	0.3	1.0	1.4	1.3	1.4	0.6
High blood pressure (mother)	1.0	1.4	4.8	0.4	-0.1	-0.8	-0.7	-0.3	-0.0	-0.3	1.4	0.9	2.1	0.2	1.8	0.4	2.2	2.2	1.1	0.8
Body mass index (BMI)	1.0	4.1	22.8	0.1	-2.5	-3.3	-3.1	-2.5	-4.8	-1.4	-0.3	-1.2	1.0	-1.4	-0.7	-2.1	0.9	0.8	-1.2	-0.5
Fluid intelligence score	1.0	2.1	10.2	-3.2	-0.9	0.9	1.2	0.2	0.9	0.2	-1.9	-1.8	-2.3	0.8	-0.9	-1.3	-1.0	-2.0	-1.0	-1.0
Neuroticism score	1.0	2.1	6.5	1.1	0.4	0.7	-0.0	1.9	-2.0	2.5	1.8	2.1	0.7	0.4	-0.6	1.9	1.1	1.5	2.1	0.2
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	7.4	0.8	-1.1	0.6	0.8	-0.3	2.7	-1.1	0.6	0.6	0.6	0.4	1.6	0.6	-0.2	0.3	0.1	2.1
Medication: Cholesterol lowering	1.0	1.5	6.9	-0.3	-0.7	-2.0	-2.3	-0.9	-1.2	-0.8	-0.4	-0.7	0.4	-2.6	-1.8	-1.2	0.7	0.1	-0.4	0.3
Arm fat mass (right)	1.0	4.0	25.5	-0.1	-2.7	-2.8	-3.0	-2.2	-5.1	-1.0	-0.7	-1.5	0.4	-1.5	-0.9	-1.9	0.5	0.4	-1.6	-0.8
Knee pain experienced in last month	1.0	1.5	6.6	-0.2	-2.6	-1.1	-1.7	-0.8	-2.1	-0.9	-0.5	-0.9	-0.3	-1.6	0.4	-1.1	-0.4	-0.4	-1.5	-0.9
Arm fat percentage (left)	1.0	3.9	30.0	-0.1	-2.4	-1.7	-2.1	-1.9	-5.5	-0.7	-1.4	-1.6	-0.6	-1.1	-1.3	-1.7	-0.5	-0.6	-2.0	-2.0
Loneliness, isolation	1.0	1.4	7.2	0.2	-1.6	-0.7	-1.4	-0.2	-2.7	0.5	-0.7	-0.9	-1.3	-1.1	-1.7	-0.5	-0.4	-0.5	-0.9	-1.5
Medication: Gliclazide	1.0	1.2	4.1	0.7	-2.0	-1.1	-1.3	-1.8	0.3	-1.8	0.1	-0.1	0.6	-1.2	1.6	-0.3	-0.3	0.2	-1.0	0.5
Arm fat mass (left)	1.0	4.0	24.1	0.4	-2.8	-2.8	-3.1	-2.1	-4.9	-1.0	-0.7	-1.6	0.5	-1.5	-0.8	-2.0	0.7	0.6	-1.5	-0.6
Illnesses of father: High blood pressure	1.0	1.2	4.0	-0.4	1.1	0.6	0.4	0.3	0.6	2.0	1.3	1.4	0.6	0.8	0.9	1.7	1.5	1.2	1.4	0.5
Arm fat-free mass (left)	1.0	5.2	20.6	0.7	-2.4	-4.5	-4.1	-1.9	-2.0	-1.5	1.0	-0.8	2.4	-2.1	-0.1	-1.9	2.7	2.6	0.2	2.3
Supplements: Calcium	1.0	1.1	3.3	-0.6	-0.9	-0.9	-1.8	-0.0	-1.8	0.3	-0.8	-1.0	-0.7	-1.7	-1.7	-1.1	0.3	-0.3	-0.9	0.1
Arm predicted mass (left)	1.0	4.9	17.2	1.0	-2.4	-4.2	-3.9	-1.8	-1.8	-1.2	1.0	-0.8	2.5	-1.8	0.1	-1.8	3.0	2.7	0.1	2.2
Ulcerative Colitis (UC)	0.9	1.7	3.5	1.4	1.6	0.5	0.4	0.6	1.6	0.9	1.6	1.7	1.7	0.4	1.9	1.8	1.4	1.3	1.1	0.9
Primary Biliary Cirrhosis	0.9	1.3	4.1	1.1	0.6	-0.8	-0.1	2.0	1.1	1.4	1.2	1.1	0.7	0.7	0.2	1.0	0.9	1.2	1.4	2.0
Heel T-Score	0.9	7.4	31.1	-2.6	3.5	5.6	4.5	-0.1	0.5	0.1	-0.3	1.4	-3.8	2.5	-0.5	2.2	-3.7	-3.0	0.1	-2.3
Lung FEV1/FVC ratio	0.9	4.5	18.8	1.9	2.2	-1.0	-0.6	1.0	-2.1	2.5	2.4	2.2	2.3	0.5	1.3	1.5	4.3	3.4	2.0	0.1
Relative age of first facial hair	0.9	1.9	8.8	-2.6	-2.2	-0.2	-0.6	-0.3	-2.8	0.2	-0.5	-0.8	-0.5	-0.4	-3.0	-1.0	0.3	-0.1	0.7	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.0	6.6	-0.0	2.1	2.6	2.1	0.7	0.4	0.8	-0.4	0.4	-2.3	1.1	-1.2	0.3	-1.9	-2.0	-0.3	-0.9
Financial difficulties in last 2 years	0.9	1.2	4.3	0.0	0.3	2.0	1.6	-0.6	-0.5	-0.5	0.7	1.0	-0.0	2.1	2.0	1.1	0.0	0.4	0.1	-1.0
Pain all over the body in last month	0.9	1.0	3.7	0.6	-0.7	-0.6	-0.9	0.3	0.9	-0.6	-0.6	-0.9	-0.7	-1.1	0.2	-1.0	-1.9	-1.2	-1.6	1.1
Impedance of arm (right)	0.9	4.3	26.8	-0.3	1.4	5.2	3.3	1.8	0.3	1.7	-1.0	0.5	-2.4	1.8	-0.5	2.1	-2.3	-2.0	-0.1	-1.9
Trunk fat-free mass	0.9	5.3	19.6	1.1	-2.3	-4.4	-4.1	-1.2	-1.2	-0.7	1.6	-0.3	2.8	-2.0	0.0	-1.4	3.0	3.2	0.8	2.8
Hip circumference	0.9	4.0	21.4	-0.5	-3.0	-2.6	-3.0	-2.1	-4.6	-0.9	-0.8	-1.8	-0.2	-1.4	-1.6	-2.3	0.1	0.1	-1.2	-0.9
Father’s age at death	0.9	1.2	4.8	-0.3	1.5	2.2	2.0	0.6	0.6	0.8	0.2	1.2	-1.0	0.6	0.1	1.8	-0.6	-0.7	0.6	-1.0
Mouth/teeth dental problems: Dentures	0.9	1.5	5.2	0.9	-1.4	-0.5	0.3	1.1	1.8	-0.4	1.3	0.9	1.5	0.8	2.3	0.7	0.8	1.1	0.4	2.2
Trunk predicted mass	0.9	5.4	19.8	1.2	-2.3	-4.4	-4.1	-1.3	-1.2	-0.8	1.7	-0.3	2.8	-2.0	-0.0	-1.4	3.0	3.2	0.8	2.7
Hair/balding pattern: Pattern 4	0.9	2.1	5.2	-1.9	2.0	1.6	1.2	-1.0	0.5	-0.6	-1.8	-1.1	-2.3	0.3	-0.9	0.1	-1.0	-2.2	-1.1	-2.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	5.4	2.3	0.4	1.2	0.4	1.4	0.7	1.1	0.9	1.0	0.6	0.3	1.1	1.0	0.0	0.6	1.3	1.6
Heart disease (mother)	0.9	1.1	4.0	-1.0	-0.9	-0.8	-1.8	0.7	-2.0	1.3	0.0	-0.2	-0.0	-2.0	-0.8	0.0	0.8	0.5	0.7	-0.2
Leg fat mass (right)	0.9	3.5	22.2	-0.1	-2.0	-2.6	-2.6	-2.2	-4.7	-0.8	-0.9	-1.5	0.1	-1.2	-1.1	-1.9	0.7	0.3	-1.5	-1.6
Suffer from ‘nerves’	0.9	1.4	6.9	1.2	0.6	0.4	0.0	2.6	0.2	2.5	1.1	1.3	0.0	0.2	1.1	1.5	0.9	1.0	1.1	-0.3
Smoking status: Previous	0.9	1.3	8.3	-0.2	0.5	2.9	1.9	0.1	-0.3	-0.2	-0.7	0.1	-1.8	0.6	-0.6	0.3	-1.2	-1.6	1.0	-0.4
Whole body fat-free mass	0.9	5.0	20.3	0.9	-2.7	-4.5	-4.3	-1.4	-2.3	-0.6	0.9	-1.0	2.0	-2.2	-0.6	-2.1	2.2	2.4	-0.0	2.0
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	4.7	0.2	2.1	1.6	1.9	-0.0	-1.1	0.1	1.2	1.5	-0.4	2.2	0.6	0.8	1.1	0.8	1.1	-0.5
Whole body water mass	0.9	5.0	20.2	0.9	-2.8	-4.5	-4.4	-1.4	-2.2	-0.7	0.8	-1.1	2.0	-2.2	-0.5	-2.1	2.2	2.3	-0.1	2.0
Financial situation satisfaction	0.9	1.1	2.7	0.7	-1.6	-0.2	-0.1	1.3	0.0	1.1	1.6	1.1	1.3	0.6	1.4	1.3	-0.1	1.2	0.8	1.0
Basal metabolic rate	0.9	4.8	18.0	0.9	-2.9	-4.2	-4.2	-1.4	-2.9	-0.6	0.7	-1.1	1.8	-2.0	-0.6	-2.1	2.1	2.2	-0.2	1.6
Commuting to job workplace: Cycle	0.9	1.1	7.4	-2.7	-0.1	-1.6	-1.3	-0.7	-1.0	-0.1	-0.1	-0.7	-0.7	-0.8	-1.1	-1.1	-0.9	-0.8	-0.4	-0.7
Heart attack/myocardial infarction (self-reported)	0.9	1.1	3.6	0.7	-1.0	-1.4	-1.9	-0.6	-0.3	-0.4	0.2	-0.3	0.8	-1.6	1.9	-0.7	0.2	0.3	-1.0	1.7
Heart disease (siblings)	0.9	1.1	4.3	1.7	-0.7	-0.9	-0.9	2.1	1.1	1.6	0.9	0.4	0.7	-0.3	0.7	0.6	0.8	0.9	0.4	1.5
Pack years of smoking	0.9	1.4	5.2	0.4	-0.5	0.6	1.6	0.5	1.3	-0.6	1.1	0.9	0.7	2.3	2.2	0.2	0.9	1.1	0.3	1.9
Neuroticism (Nagel 2018)	0.8	1.9	4.8	1.9	0.8	0.7	-0.1	1.0	-2.2	1.7	1.4	1.9	0.7	0.2	-0.8	2.1	1.5	1.8	1.7	-0.3
HbA1C	0.8	0.9	2.8	0.7	-0.4	-1.6	-1.7	-0.5	0.6	-1.1	-0.9	-1.3	-0.1	-1.1	-1.1	-0.8	0.9	0.4	-0.7	-0.5
Waist Hip Ratio (WHR)	0.8	3.8	14.7	0.3	1.9	3.0	2.9	1.8	2.2	1.3	0.8	2.0	0.3	2.1	3.8	2.9	0.9	0.9	0.2	0.4
Type 2 Diabetes (T2D) (2018)	0.8	1.6	4.1	0.4	-1.1	-1.5	-1.4	-2.0	-1.6	-1.9	-1.3	-0.8	0.1	-1.7	1.1	-0.8	0.3	0.0	-1.8	-0.1
Medication: Co-codamol	0.8	0.9	2.8	0.5	-0.6	1.1	1.5	0.4	0.2	-0.3	1.1	1.2	-0.2	1.5	1.7	1.0	-0.3	0.3	0.9	0.7
Diabetes (father)	0.8	0.9	3.0	-0.7	0.3	-1.7	-1.1	-0.1	-0.8	0.1	1.6	1.3	1.1	-0.5	1.0	0.8	0.7	1.4	0.7	0.2
Trunk fat percentage	0.8	3.2	24.7	0.5	-2.0	-0.8	-1.7	-1.7	-5.0	-0.5	-1.5	-1.7	-0.8	-0.7	-1.5	-1.5	-0.1	-0.6	-1.8	-1.9
Townsend deprivation index at recruitment	0.8	1.1	3.6	0.2	-1.1	1.1	1.5	1.9	0.4	1.7	0.2	0.2	-1.4	1.8	0.5	0.1	-0.7	-0.4	-0.8	-0.4
Leg predicted mass (left)	0.8	4.0	14.3	0.6	-2.9	-3.8	-3.8	-1.2	-3.6	-0.1	-0.1	-1.6	0.7	-1.8	-1.1	-2.5	0.7	1.0	-0.9	0.5
Trunk fat mass	0.8	3.5	24.4	0.7	-2.4	-1.9	-2.5	-1.8	-4.9	-0.5	-1.1	-1.8	-0.3	-1.1	-1.4	-1.8	0.5	0.0	-1.6	-1.3
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	3.7	1.0	0.7	1.9	1.6	0.2	0.6	0.2	1.1	1.4	0.1	1.8	0.5	1.3	0.1	0.3	1.7	-0.1
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	2.6	0.7	-1.5	1.1	0.2	1.5	0.7	1.1	0.9	0.4	1.5	0.4	1.6	0.4	0.5	1.0	1.0	1.0
Allergy	0.8	1.7	6.0	-2.2	1.0	-0.3	2.2	1.3	2.5	0.5	1.0	1.2	0.7	2.1	1.4	0.9	0.4	0.4	0.5	0.3
Weight	0.8	4.1	17.8	0.8	-2.7	-3.2	-3.6	-1.9	-4.2	-0.8	-0.2	-1.5	0.8	-1.7	-1.3	-2.2	1.2	1.1	-1.0	0.0
Arm fat percentage (right)	0.8	3.3	28.9	-0.2	-2.5	-1.4	-1.9	-1.9	-5.4	-0.8	-0.9	-1.2	-0.4	-0.8	-0.9	-1.3	-0.4	-0.3	-1.7	-1.7
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.2	4.0	1.4	-2.0	-0.4	-1.8	1.1	-2.0	1.2	0.9	0.2	0.9	-0.8	0.3	0.2	0.4	1.2	0.3	0.9
Impedance of arm (left)	0.8	3.8	16.3	-0.2	1.0	4.0	2.3	1.5	0.0	1.7	-2.0	-0.7	-2.9	0.9	-1.2	1.0	-2.6	-2.6	-1.0	-2.2
Breastfed as a baby	0.8	1.0	4.3	1.2	0.1	2.1	1.7	0.8	1.2	0.4	-0.8	-0.3	-0.8	1.5	0.6	0.6	-0.3	-0.3	0.6	0.7
Tense / ‘highly strung’	0.8	1.3	7.7	-0.3	-0.6	-0.6	-1.5	-0.1	-2.2	0.6	-0.9	-1.0	-1.1	-1.5	-2.8	-0.9	-0.3	-0.8	0.0	0.1
Body fat percentage	0.8	3.2	26.2	0.2	-1.8	-1.1	-1.7	-2.0	-5.1	-0.8	-1.3	-1.5	-0.5	-0.7	-1.2	-1.4	0.0	-0.3	-1.7	-2.2
Leg fat percentage (right)	0.8	3.0	22.7	-0.5	-1.2	-1.5	-1.4	-2.4	-4.8	-1.2	-1.1	-1.2	-0.4	-0.6	-1.2	-1.3	0.3	-0.2	-1.5	-2.5
Age at first live birth	0.8	1.4	7.4	-0.7	0.3	0.5	0.5	0.2	-1.2	0.7	-1.2	-0.9	-1.3	-0.1	-2.7	-0.7	-0.8	-1.4	0.4	-2.4
Angina (self-reported)	0.8	1.0	2.9	0.9	0.4	-0.7	-0.8	0.4	0.4	0.1	1.2	1.0	1.7	-0.1	1.6	0.9	1.7	1.7	0.3	1.1
Whole body fat mass	0.8	3.2	22.0	0.3	-2.4	-2.0	-2.4	-1.8	-4.7	-0.6	-0.8	-1.5	0.1	-1.0	-1.0	-1.7	0.7	0.3	-1.4	-1.2
Age at last live birth	0.8	1.1	3.3	0.7	-0.4	0.9	0.8	1.8	-0.6	1.8	-0.4	-0.4	-1.2	0.5	-1.4	-0.3	-0.9	-1.1	0.8	-1.7
Leg fat-free mass (right)	0.8	4.0	15.2	0.9	-3.0	-3.8	-3.9	-0.8	-3.2	0.1	0.2	-1.4	1.0	-1.9	-1.1	-2.4	0.9	1.3	-0.6	1.1
Back pain experienced in last month	0.8	1.2	9.6	1.2	-3.1	0.2	-1.1	0.7	0.1	0.2	0.6	-0.1	0.5	-0.9	0.6	-1.0	0.3	0.8	0.5	1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.7	10.4	0.4	-1.0	-0.7	-0.3	-0.0	-1.8	0.5	-1.3	-1.5	-1.1	-0.1	-1.6	-1.1	-1.0	-1.0	-1.5	-3.2
Leg predicted mass (right)	0.8	4.1	15.4	0.9	-3.0	-3.8	-3.9	-0.7	-3.1	0.2	0.2	-1.5	1.0	-1.9	-1.2	-2.4	1.0	1.3	-0.6	1.2
Number of self-reported non-cancer illnesses	0.8	1.3	3.6	1.5	-1.3	-0.1	-1.9	-1.7	-1.9	-1.4	-0.5	-0.8	1.0	-1.6	0.3	-0.9	1.1	0.5	-0.4	0.3
Supplements: Fish oil (including cod liver oil)	0.8	1.1	6.4	2.3	-0.5	0.1	-0.2	0.9	1.4	-0.4	0.4	0.3	0.9	-0.4	0.6	-0.1	0.6	1.0	0.5	2.5
Medication: Bendroflumethiazide	0.8	1.2	10.3	-1.5	0.4	-0.1	0.7	-0.6	-1.4	0.4	-1.1	-0.6	-0.7	0.8	-0.8	-0.2	0.2	-0.6	-0.5	-3.2
Medication: Lisinopril	0.8	1.1	4.4	0.9	-1.8	-1.1	-0.9	-0.7	-2.1	-0.0	-1.1	-1.3	0.0	-0.6	-0.1	-0.5	-0.1	-0.6	-1.6	-1.1
Irritability	0.8	1.3	5.1	0.8	-2.3	-1.5	-1.6	0.6	-1.6	0.7	0.5	-0.1	1.2	-0.3	-0.6	-0.5	1.0	1.1	0.3	1.7
Ever depressed for a whole week	0.8	1.0	2.7	-0.9	-1.1	-0.2	0.0	1.6	0.2	1.4	1.4	0.9	1.2	0.1	1.3	1.2	-0.0	0.8	1.5	0.2
Leg fat mass (left)	0.8	2.9	19.9	0.2	-2.0	-2.4	-2.4	-1.9	-4.5	-0.7	-0.5	-1.2	0.3	-1.0	-1.1	-1.7	1.0	0.6	-1.1	-1.1
Prostate Cancer	0.7	1.0	3.2	-0.5	1.6	0.9	1.2	1.6	1.0	1.8	0.2	0.6	-0.5	1.1	-0.9	0.3	-0.2	-0.2	1.4	0.2
Age at First Birth	0.7	1.0	5.0	-0.2	-0.5	2.2	0.7	0.4	-1.6	1.2	-0.9	-1.0	-0.7	0.7	-0.5	-0.1	0.1	-0.7	-0.4	-1.9
Crohns Disease (2012)	0.7	1.1	4.9	0.5	-0.6	-1.5	-2.2	0.5	-0.3	1.0	-0.3	-0.8	1.1	-1.7	0.0	-1.0	1.4	0.8	-0.4	1.0
Angina	0.7	0.9	2.6	1.1	-0.0	-0.5	-0.8	0.5	0.3	0.2	1.1	0.8	1.6	-0.1	1.5	0.7	1.6	1.6	0.1	1.1
Leg fat-free mass (left)	0.7	3.9	13.9	0.7	-2.8	-3.7	-3.7	-1.1	-3.6	-0.0	-0.1	-1.6	0.8	-1.7	-1.0	-2.4	0.7	1.1	-0.9	0.5
Fed-up feelings	0.7	1.3	11.7	0.4	-1.3	-0.7	-0.8	1.3	-3.4	2.0	0.2	0.0	-0.4	-0.0	-1.1	0.0	0.3	0.3	0.4	-0.5
Relative age voice broke	0.7	1.1	4.9	-1.2	-0.0	0.3	0.6	0.1	0.2	0.1	0.8	0.6	1.1	0.7	-1.8	0.3	2.2	1.5	1.8	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	4.6	0.1	1.9	2.1	1.6	0.9	1.0	0.9	0.4	0.9	-1.7	0.5	-1.5	0.7	-1.8	-1.6	0.8	-0.2
Heart attack	0.7	0.8	3.3	0.8	-0.8	-1.1	-1.4	-0.5	-0.3	-0.4	0.3	-0.1	0.7	-1.2	1.8	-0.6	0.4	0.4	-0.8	1.7
Diabetes (self-reported)	0.7	1.1	4.2	1.6	-0.9	-0.0	-0.5	-2.1	-1.1	-2.1	-1.4	-0.9	-0.1	-0.8	0.6	-0.8	0.4	-0.1	-0.8	-0.3
Medication: Simvastatin	0.7	1.1	3.8	-0.8	-1.1	-2.0	-1.5	-0.3	-0.3	-0.4	-0.5	-0.6	-0.5	-1.9	-0.5	-0.8	-0.9	-0.7	-1.7	0.2
Length of working week for main job	0.7	0.8	2.5	1.2	-1.2	-0.9	-1.1	-1.6	-0.2	-1.4	-0.1	-0.5	-0.0	-0.9	-1.0	-1.1	0.2	0.2	0.2	0.8
Exposure to tobacco smoke at home	0.7	0.8	1.9	0.2	1.3	-0.5	0.3	1.3	1.2	1.3	1.4	1.4	0.5	0.4	0.2	1.0	0.2	0.7	0.8	0.7
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	4.9	0.3	-0.2	1.7	1.7	1.1	2.2	0.4	0.5	0.7	-0.4	1.6	1.4	1.0	-0.4	0.1	0.6	1.0
Number of full brothers	0.7	0.9	4.7	-0.7	-0.0	2.2	1.3	0.5	-0.5	0.4	-0.3	0.4	-1.5	0.9	0.1	1.0	-1.3	-1.0	-0.8	-0.3
Pulse rate, automated reading	0.7	2.4	7.1	-0.9	-1.3	0.2	1.1	0.2	-2.2	0.6	2.5	1.8	0.9	2.7	2.0	1.0	1.3	2.0	1.5	-0.7
Had major operations	0.7	0.8	3.7	1.9	-0.0	1.6	0.6	0.9	1.4	0.6	0.2	-0.1	0.3	0.7	1.7	0.3	0.5	0.2	0.4	0.6
Mood swings	0.7	1.3	8.8	3.0	-0.9	-0.3	-0.8	1.2	-1.6	1.6	0.9	0.8	0.9	-0.0	-0.4	0.0	0.8	1.3	0.3	0.9
Commuting to job workplace: Walk	0.7	0.8	3.6	1.4	-0.3	0.5	0.8	0.8	0.1	0.5	-0.6	-0.4	-1.2	0.7	1.2	-0.6	-1.9	-1.0	-0.7	0.2
Mineral and other dietary supplements	0.7	0.9	6.6	-1.5	0.3	-1.3	-0.7	-1.0	-1.5	0.2	0.1	-0.2	0.2	-0.0	-0.8	0.2	-0.1	-0.0	-0.3	-2.6
Leg fat percentage (left)	0.7	2.6	20.2	-0.1	-1.3	-1.4	-1.5	-2.2	-4.5	-1.2	-0.9	-1.0	-0.2	-0.6	-1.4	-1.3	0.6	-0.0	-1.2	-1.9
Cholesterol lowering medication	0.7	1.0	6.1	2.5	0.1	0.2	0.5	1.5	0.6	0.4	0.8	1.3	0.6	-0.3	1.7	1.5	-0.2	0.5	0.2	0.1
Mean Putamen Volume	0.6	0.7	2.5	-1.1	1.3	0.0	1.0	-1.6	-0.1	-1.3	-0.7	-0.2	-0.2	0.8	0.6	-0.1	-0.4	-0.5	-0.7	-1.1
Respiratory disease	0.6	1.3	5.4	0.3	0.5	-0.2	-1.8	-1.3	-2.3	-0.7	-0.5	-0.5	-0.4	-1.6	-2.2	-0.0	0.4	0.0	0.3	-1.5
Neuroticism	0.6	1.5	4.8	1.4	0.4	0.4	0.0	1.3	-1.3	1.5	1.5	2.0	0.8	-0.1	-0.7	2.2	0.4	1.1	1.9	0.2
Hearing difficulty/problems: Yes	0.6	1.0	3.1	-0.0	-0.0	1.7	1.4	0.6	0.3	0.1	-1.0	-0.5	-1.7	0.4	0.4	-0.2	-1.7	-1.6	-0.2	-1.2
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	2.9	-1.6	-0.6	1.7	1.0	-0.1	-0.2	-0.1	1.1	1.2	0.1	0.7	0.7	1.3	-0.6	0.0	0.5	0.0
Medication: Metformin	0.6	0.8	3.4	1.0	-0.2	-0.5	-0.6	-1.8	-0.7	-1.6	-1.1	-0.7	-0.5	-1.2	-0.2	-0.6	-0.3	-0.7	-0.8	-0.7
Taking other prescription medications	0.6	0.9	2.3	1.1	-1.5	-0.0	-1.3	-0.5	-1.1	-0.2	-0.9	-1.3	-0.3	-1.4	-0.5	-0.9	-1.0	-0.7	-0.7	-0.8
Qualifications: CSEs or equivalent	0.6	0.8	2.4	0.1	-0.3	-1.5	-1.5	-0.5	-1.2	-0.2	0.0	-0.1	1.1	-1.4	-1.2	-0.1	0.8	0.7	-0.1	-0.9
High blood pressure	0.6	1.7	5.0	0.1	0.4	-0.8	-0.5	0.7	-0.4	0.9	1.7	1.5	2.2	0.2	2.1	1.3	2.1	2.1	0.9	-0.9
Impedance of leg (left)	0.6	2.8	11.4	0.7	2.3	3.4	2.4	1.0	2.9	0.6	0.4	1.3	0.1	1.5	0.9	2.4	1.3	0.4	1.2	0.5
Qualifications: None of the above	0.6	1.3	9.9	0.8	0.4	-0.0	-0.4	-2.4	0.4	-3.1	-0.2	0.2	0.8	-0.6	1.2	-0.2	0.2	0.3	-1.4	0.5
Worrier / anxious feelings	0.6	1.1	2.9	0.8	1.5	-0.3	-0.6	0.2	-0.8	0.6	1.2	1.5	1.0	-0.5	-0.7	1.5	1.0	1.4	1.7	-0.0
Lung cancer (father)	0.6	0.7	3.3	-0.2	0.2	0.7	1.3	0.6	0.5	0.5	0.0	0.2	-0.7	1.8	0.9	1.0	-1.4	-0.7	0.2	-0.4
Peak expiratory flow (PEF)	0.6	1.4	5.4	1.9	-0.2	-1.4	-1.4	0.7	-0.4	1.5	0.6	-0.0	1.7	-0.7	0.7	-0.1	2.3	1.8	0.6	-0.5
Glaucoma (self-reported)	0.6	0.7	1.7	-0.6	1.2	1.2	1.1	-1.3	0.3	-1.2	0.3	0.5	-0.2	1.2	-0.8	0.5	-0.4	-0.2	0.6	-0.9
High blood pressure (siblings)	0.6	0.8	3.0	0.6	-0.1	-1.7	-1.2	0.2	-0.4	0.5	1.3	1.0	1.0	-1.3	1.5	0.4	0.1	0.7	-0.0	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	1.8	-0.9	-0.4	-0.5	0.0	0.6	0.2	0.5	1.4	1.0	1.1	0.7	1.1	0.8	1.1	1.3	0.5	0.7
Emphysema/chronic bronchitis	0.6	0.7	3.1	1.8	0.5	0.1	-0.7	-1.4	-0.1	-1.7	-0.3	-0.2	-0.3	-1.0	0.5	-0.8	0.3	-0.2	-0.2	1.1
Medication: Omeprazole	0.6	0.7	2.8	1.7	0.7	0.6	0.7	0.6	0.8	0.3	0.8	1.2	-0.0	0.2	1.1	1.5	-0.8	0.1	0.2	0.7
Hypertension (Self-reported)	0.6	1.6	5.1	0.2	0.4	-0.8	-0.4	0.6	-0.4	0.8	1.5	1.3	2.3	0.3	2.1	1.4	2.1	1.9	0.8	-0.9
Diabetes diagnosed by doctor	0.6	1.0	3.9	0.9	-0.9	-0.2	-0.6	-2.0	-1.4	-1.9	-1.3	-0.7	-0.3	-1.2	0.6	-0.6	-0.2	-0.4	-1.2	-0.5
Eye problems/disorders: Glaucoma	0.6	0.7	2.4	0.3	1.1	1.5	1.1	-1.1	0.7	-1.4	0.4	0.7	-0.0	1.0	-0.4	0.7	-0.4	-0.1	0.7	-0.3
Alcohol drinker status: Never	0.6	0.7	2.4	-1.3	0.5	-1.3	-0.7	0.6	-1.4	1.6	0.4	0.2	-0.1	0.5	0.5	-0.1	0.3	0.5	-1.2	-1.1
Impedance of whole body	0.6	3.2	20.8	0.1	2.1	4.6	2.9	1.2	1.4	1.2	-1.2	0.2	-2.0	1.4	-0.1	1.9	-1.2	-1.6	-0.0	-1.4
Depressed Affect (Nagel 2018)	0.5	1.1	9.0	1.1	-1.6	-0.8	-1.3	-0.1	-3.0	0.6	0.1	0.0	0.0	-0.7	-1.5	0.0	0.2	0.5	-0.1	-0.6
Crohns Disease (2017)	0.5	1.0	4.1	0.4	-0.0	-0.6	-2.0	-1.0	-1.5	-0.1	-0.2	-0.5	0.7	-1.8	-0.2	-0.9	1.7	0.7	0.1	1.0
Irritable Bowel Disease (IBD)	0.5	1.3	5.1	1.3	1.0	-0.6	-1.2	-0.2	0.2	0.4	1.0	0.9	1.9	-0.9	1.2	0.6	2.3	1.6	0.8	1.2
Ovarian Cancer	0.5	0.6	2.6	0.4	-0.2	0.1	-0.1	0.1	-0.4	-0.3	-1.6	-1.2	-1.4	-0.7	0.0	-0.8	-0.4	-1.2	-1.0	-0.6
Neuroticism (2016)	0.5	0.8	4.0	2.0	0.7	0.9	-0.0	0.9	-1.3	0.6	0.2	0.7	-0.8	-0.7	-1.7	0.2	-0.4	-0.4	0.7	-0.0
Cardiovascular Disease	0.5	1.6	6.7	1.8	0.1	-0.5	-0.4	1.0	0.1	0.7	0.8	0.7	2.1	0.2	2.6	1.0	2.4	1.8	0.4	-0.0
Hypothyroidism (self reported)	0.5	1.1	9.1	0.4	-0.2	0.4	0.1	-1.1	3.0	-1.4	-0.1	-0.7	1.2	0.2	1.9	-0.4	0.4	0.0	-0.3	0.6
Medication for hormone replacement therapy	0.5	0.5	1.7	0.8	-0.7	-1.2	-1.0	0.5	0.4	-0.2	0.8	0.4	0.4	-1.1	0.6	-0.1	-0.7	0.0	0.2	1.3
Impedance of leg (right)	0.5	2.4	9.9	0.2	2.5	3.1	2.6	0.6	2.6	0.4	-0.2	0.8	-0.3	1.7	1.1	2.1	0.7	-0.1	0.8	-0.5
Hearing difficulty/problems with background noise	0.5	0.7	3.8	1.3	1.0	1.9	1.1	0.5	0.9	-0.5	-0.2	0.3	-0.5	-0.0	0.8	0.2	0.6	-0.4	1.3	-0.3
Mouth/teeth dental problems	0.5	0.7	2.8	1.0	0.7	-0.2	-0.1	-0.7	0.5	-0.5	-1.7	-0.9	-0.3	-1.1	-1.6	-0.5	-0.3	-0.8	-0.6	-0.9
Illnesses of siblings	0.5	0.7	1.9	-0.9	0.1	0.3	0.2	-1.3	0.2	-1.4	-1.4	-1.3	-0.4	0.1	-1.3	-0.8	-0.6	-1.0	-0.6	0.1
Time employed in main current job	0.5	0.5	2.7	0.0	0.8	0.7	0.2	-0.6	0.4	0.3	0.5	0.4	1.0	0.4	1.0	0.5	1.7	1.1	0.1	0.6
Pulse rate	0.5	0.9	2.7	-1.1	-0.8	-0.3	0.2	1.6	-0.8	1.6	1.5	1.1	0.5	0.8	1.0	0.4	0.4	0.9	0.9	0.2
Illnesses of mother	0.5	0.6	2.4	1.3	0.7	0.2	1.1	-0.7	1.5	-1.3	-0.1	0.1	-0.2	0.9	-0.5	0.0	-0.7	-0.7	-0.3	-0.4
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.1	0.6	-1.4	-0.3	-0.9	1.0	0.5	0.7	0.4	-0.3	0.3	-0.6	1.4	-0.2	-0.4	0.2	-0.3	1.2
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	3.3	-0.7	-1.3	-0.8	-1.8	-0.1	-1.3	0.6	0.6	-0.2	0.4	-1.2	0.4	-0.2	0.0	0.4	0.1	0.5
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	7.0	0.5	-0.9	0.4	-0.3	-0.9	2.6	-0.8	-0.7	-1.2	0.6	-0.3	1.7	-0.8	0.2	-0.3	-0.9	1.2
Medication: Ventolin 100micrograms inhaler	0.5	0.6	2.5	1.5	1.0	0.5	-0.0	0.3	-0.4	0.5	0.1	-0.1	-0.3	0.0	-1.2	-0.4	1.3	0.3	0.7	-1.6
Number of children fathered	0.5	0.6	2.4	0.7	0.7	-0.6	0.3	-0.9	0.3	-1.6	0.9	1.0	0.9	0.1	-0.1	0.1	0.8	0.9	0.7	0.6
Alcohol intake frequency.	0.5	1.2	4.5	-0.0	-0.2	-2.1	-2.0	-2.0	-1.5	-0.9	-0.5	-0.6	0.5	-1.3	-0.1	-0.2	-0.0	0.1	-1.4	-0.6
Leg pain on walking	0.5	0.6	2.1	1.3	-0.4	0.4	0.5	0.1	-0.3	-0.5	1.1	1.3	0.8	0.6	1.4	0.7	0.7	0.8	-0.3	0.4
Illnesses of father: Heart disease	0.5	0.7	1.7	-0.2	-0.7	-1.0	-1.3	-1.2	0.5	-1.1	0.2	-0.2	1.0	-1.1	-0.4	0.1	0.8	0.8	1.1	0.3
Asthma (self-reported)	0.5	1.1	5.6	-0.1	0.4	-0.3	-1.2	-0.1	-2.1	0.3	-0.1	-0.2	-1.1	-1.1	-1.8	0.1	-0.1	-0.3	0.5	-2.4
Average weekly champagne plus white wine intake	0.5	0.7	3.1	-0.9	-0.3	-1.4	-1.2	-1.4	0.0	-1.8	0.3	0.0	0.4	-0.9	-0.8	-0.5	0.2	0.3	-0.0	1.1
Number of operations (self-reported)	0.5	0.8	4.1	-0.0	-0.9	0.4	0.2	0.1	0.1	-0.8	-1.0	-0.7	-0.5	-0.7	0.8	0.1	-2.0	-1.7	-1.3	0.1
Vascular/heart problems diagnosed by doctor	0.5	1.4	5.1	-0.1	-0.4	1.1	0.9	-0.5	0.3	-0.7	-1.5	-1.2	-2.1	0.3	-2.3	-1.1	-1.6	-1.8	-0.2	0.6
Alcohol drinker status: Previous	0.5	0.6	1.7	1.0	-1.2	0.9	0.8	0.1	0.5	-0.1	0.8	0.9	0.6	0.5	1.2	1.3	-0.1	0.4	0.5	0.5
Breast Cancer	0.4	1.1	5.5	-0.6	-0.7	-2.4	-1.8	0.3	-2.0	0.4	0.6	-0.5	1.0	-0.7	-0.7	-0.7	0.5	0.8	-0.1	-0.7
Fasting Glucose	0.4	0.4	1.6	0.5	0.1	-0.2	-0.4	-1.0	0.3	-1.2	-1.1	-1.2	0.3	-0.1	0.1	0.0	-0.6	-0.4	-1.0	-0.2
Blood Platelet Count	0.4	4.9	15.0	0.3	-2.8	1.2	2.8	1.9	1.7	1.3	3.9	3.5	0.3	2.9	-1.2	1.9	0.4	1.6	3.4	1.8
Lung FVC	0.4	2.2	6.7	1.0	-2.0	1.8	2.6	2.0	1.0	1.2	-0.7	-0.6	-1.4	2.1	-0.8	-0.4	-1.8	-1.3	0.2	-1.7
Sensitivity / hurt feelings	0.4	0.7	2.0	-0.2	1.3	1.2	1.0	0.5	-0.3	1.0	0.3	1.1	-0.1	0.7	-0.7	1.4	0.6	0.3	1.3	-0.1
Vitamin and mineral supplements	0.4	0.5	1.6	-0.8	0.7	-0.1	0.5	0.4	-0.2	0.5	0.8	0.6	1.1	1.2	0.7	0.5	1.2	0.9	0.2	-0.5
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.9	1.4	0.3	-1.3	-0.8	0.9	-0.3	0.7	0.7	0.1	0.7	-0.2	-0.4	-0.4	0.4	0.5	-0.1	1.0
Serious illness, injury or assault to yourself	0.4	0.5	1.6	0.4	-0.5	1.0	-0.7	-0.4	-0.3	0.2	-0.8	-0.7	-0.5	-0.9	-0.1	-0.7	-0.9	-0.7	-0.2	1.3
Hayfever, allergic rhinitis or eczema	0.4	0.8	3.5	1.2	-0.1	0.6	-1.1	-0.4	-1.9	0.4	-0.9	-0.7	-0.9	-1.0	-1.5	-0.5	-0.4	-0.4	-0.3	-0.9
Waist circumference	0.4	1.5	13.5	0.2	-1.7	-0.9	-1.2	-1.6	-3.7	-0.8	-0.1	-0.4	0.5	-0.1	0.4	-0.3	0.7	0.8	-1.0	-1.1
Alcohol intake versus 10 years previously	0.4	0.5	1.4	-0.4	-0.8	-0.5	-0.8	0.8	-0.3	1.0	0.9	0.5	0.6	-0.1	0.9	0.6	1.1	1.2	0.3	0.4
Number of live births	0.4	0.6	1.8	-1.3	-0.6	-0.5	-0.4	1.1	0.9	0.4	-0.7	-0.8	-0.4	-0.5	1.0	-0.5	-0.6	-0.6	-0.9	0.7
Asthma	0.4	0.7	4.7	0.4	0.2	-0.0	-1.0	-0.1	-1.5	0.3	0.1	-0.1	-1.0	-0.8	-1.5	0.2	0.1	-0.2	0.7	-2.2
Depression (self-reported)	0.4	0.5	2.4	1.5	-0.1	-0.5	-0.8	0.0	-0.7	0.9	-0.5	-0.4	0.6	-0.8	0.1	-0.4	1.1	0.4	-0.4	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.1	4.8	2.2	-1.2	0.1	0.1	1.5	-0.1	1.7	0.5	-0.3	0.5	0.9	-0.2	-0.3	1.9	1.3	1.0	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	1.8	1.3	0.1	0.3	0.6	1.1	0.1	1.1	0.7	0.8	0.5	0.6	0.5	0.1	1.0	0.9	1.1	0.1
Handedness (chirality/laterality): Left-handed	0.4	0.4	2.2	-0.0	1.5	-0.7	0.6	0.3	1.2	0.2	0.3	0.3	0.1	1.2	0.5	0.0	0.6	0.6	0.3	0.0
Medication for cholesterol	0.4	0.7	4.1	-2.0	0.1	-0.5	-0.4	-0.8	-0.7	-0.2	0.0	-0.4	-0.3	0.5	-1.9	-1.0	0.2	0.2	0.5	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	3.1	-0.3	-0.4	-0.4	-0.4	-0.6	0.0	-0.8	1.1	0.6	1.0	0.2	0.2	0.2	0.2	0.9	0.0	1.8
Ever taken oral contraceptive pill	0.4	0.4	1.5	0.3	0.5	1.2	0.5	0.4	0.2	0.2	0.9	1.0	-0.4	0.0	0.7	0.9	-1.0	-0.0	0.8	0.2
Tinnitus: Yes, now most or all of the time	0.4	0.4	1.8	0.6	-0.3	0.5	0.8	1.3	1.3	0.6	0.3	0.2	-0.4	0.7	-0.1	0.2	-0.9	-0.4	-0.2	0.4
Medication: Blood pressure	0.4	0.7	2.6	0.6	0.2	0.4	0.3	0.5	0.4	0.5	0.6	0.6	1.4	0.3	1.6	1.2	1.4	1.0	0.2	-1.1
Ever had prostate specific antigen (PSA) test	0.4	0.5	2.5	0.3	0.7	-0.6	-0.8	0.1	0.7	-0.1	0.4	0.1	0.7	-0.8	-1.2	0.1	1.6	0.7	0.5	-0.0
Basal cell carcinoma (self-reported)	0.4	0.5	1.7	1.2	0.1	-0.4	-0.5	0.4	-1.3	0.5	0.1	-0.2	-0.9	0.2	-0.9	-0.5	-0.9	-0.4	-0.5	-1.1
Coronary Artery Disease (CAD)	0.3	0.3	1.6	0.2	0.1	0.6	0.5	1.2	0.3	1.0	-0.8	-0.6	0.4	0.0	0.4	0.1	-0.1	-0.4	-0.5	-0.9
LDL Cholesterol	0.3	0.5	1.3	0.6	-0.8	-1.1	-0.8	-0.8	0.6	-1.1	0.3	-0.0	0.9	-0.5	-0.1	-0.1	1.1	0.8	0.5	0.7
Triglycerides	0.3	0.5	1.7	-1.3	-0.0	-0.2	-0.5	-0.8	0.3	-0.7	-0.8	-0.6	-1.1	-0.5	0.4	-0.5	-0.6	-0.9	-0.6	-0.4
Type 2 Diabetes (T2D) (2012)	0.3	0.3	1.3	-0.3	0.8	0.6	1.1	-0.4	0.5	-0.2	0.3	0.7	0.1	0.7	0.7	0.5	0.4	0.2	0.4	-0.2
Ulcerative Colitis	0.3	0.4	1.9	0.2	0.6	0.1	-0.1	0.9	0.4	1.4	0.5	0.6	0.3	-0.3	0.8	0.9	0.5	0.1	0.4	-0.7
Allergy or Eczema	0.3	0.7	3.3	1.6	0.2	1.0	-0.5	-0.0	-1.8	0.9	-0.3	-0.1	-0.5	-0.1	-1.3	0.0	0.9	0.4	0.3	-1.1
Supplements: Zinc	0.3	0.3	2.8	0.6	0.0	0.2	-0.3	0.4	-1.7	0.4	-0.4	-0.5	-0.7	0.3	0.3	-0.4	-0.3	-0.4	-0.5	-0.3
Multivitamins +/- minerals	0.3	0.4	1.5	1.2	-0.3	-0.6	-0.7	-0.6	0.1	-0.7	-0.6	-0.5	-0.6	-1.1	0.1	-0.3	-0.5	-0.4	-0.2	0.4
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	0.9	-0.4	-0.5	-1.0	-0.7	-1.0	-0.4	-0.8	-0.5	-0.4	-0.1	-0.7	-0.2	-0.9	-0.2	-0.3	-0.8	0.4
Medication: Atenolol	0.3	0.3	1.9	-0.2	0.6	-0.8	-0.6	0.5	0.2	0.4	0.2	0.5	0.8	-1.4	0.8	0.5	0.2	0.1	-0.2	-0.5
Sitting height	0.3	2.0	6.1	1.0	-1.3	-2.4	-2.4	-0.1	-0.1	-0.2	-0.5	-1.8	-0.2	-1.3	-2.5	-2.4	0.7	0.3	-0.4	1.0
Hair/balding pattern: Pattern 3	0.3	0.5	3.4	0.2	0.1	1.0	0.5	0.2	-1.1	-0.2	-0.0	0.6	-0.5	-0.4	-0.8	0.4	-1.8	-0.8	-0.1	0.0
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	1.9	-0.5	-1.2	-0.4	-0.7	0.2	0.3	0.2	0.5	0.0	0.7	-0.0	0.1	-0.2	-0.1	0.6	-0.1	1.4
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	1.7	-0.4	-1.0	1.2	0.9	1.0	1.0	1.3	-0.4	-0.5	-0.2	0.5	-0.1	-0.3	-0.5	-0.5	0.3	0.6
Gout (self-reported)	0.3	0.4	2.0	-1.4	-0.5	-1.0	-0.5	1.0	-0.3	1.0	0.5	0.4	0.3	0.0	0.5	0.6	0.4	0.5	0.2	0.4
Forced vital capacity (FVC), Best measure	0.3	1.0	3.9	1.3	-1.6	0.6	0.7	2.0	0.7	1.7	0.1	-0.6	-0.3	1.3	-0.3	-0.2	0.5	0.4	0.7	-1.0
Wheeze or whistling in the chest in last year	0.3	0.5	3.3	1.8	-0.6	0.6	-0.1	1.0	-0.8	0.5	0.3	0.5	-0.1	-0.0	1.2	0.7	0.6	0.5	0.4	-0.3
Medication: Blood pressure	0.3	0.4	2.3	-0.3	0.7	-0.8	-0.7	-1.1	-1.5	-0.2	-0.1	-0.1	0.8	-0.6	-0.5	-0.2	0.4	0.1	-0.1	-1.0
Medication: Ibuprofen	0.3	0.4	2.7	-0.5	-1.7	-0.4	-1.0	0.0	0.3	0.3	0.3	-0.2	0.3	-0.6	0.0	-0.3	-0.4	0.1	-0.1	1.4
Medication: Aspirin	0.3	0.4	1.5	1.2	-0.8	-0.1	-0.3	-0.1	0.9	-0.9	-0.2	-0.0	0.1	-1.0	-0.4	-0.2	-0.8	-0.6	-0.7	0.6
Illnesses of siblings: Diabetes	0.3	0.3	1.2	0.2	-0.3	0.7	0.6	-0.2	-0.4	-0.1	0.4	0.8	0.3	0.5	1.1	0.7	0.7	0.7	-0.4	0.6
Long-standing illness, disability or infirmity	0.3	0.5	2.0	0.9	-1.1	0.0	-1.0	0.5	-0.7	0.5	0.5	0.5	0.9	-1.4	-0.0	0.6	0.2	0.7	-0.0	0.2
Ever had bowel cancer screening	0.3	0.4	2.6	0.1	0.3	0.1	-0.1	-1.3	-0.2	-1.6	0.2	0.4	0.6	-0.6	-0.3	0.1	-0.6	-0.3	0.4	0.7
Medication: Aspirin	0.3	0.4	1.2	1.1	-0.5	0.4	0.1	0.3	1.0	-0.5	0.5	0.7	0.6	-0.8	0.3	0.6	-0.5	-0.1	-0.3	1.0
Miserableness	0.3	0.5	5.2	-0.1	0.2	0.1	0.3	0.8	-2.3	0.9	0.7	0.9	0.3	0.6	0.1	0.4	-0.3	0.5	0.3	-0.0
Risk taking	0.3	0.4	2.0	-0.5	-0.9	1.0	0.7	0.3	-0.6	-0.0	-0.1	-0.3	-0.5	0.6	-0.1	-0.2	-1.4	-1.0	-0.4	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.1	1.0	0.4	0.6	0.5	0.4	0.6	0.2	0.3	0.7	-0.2	0.2	0.7	1.0	-0.8	0.0	-0.0	0.7
Major Depression (MDD)	0.2	0.2	0.7	0.3	0.2	-0.8	-0.3	0.5	-0.2	0.7	0.6	0.6	0.5	-0.4	-0.1	0.3	-0.1	0.6	0.3	0.1
HDL Cholesterol	0.2	0.4	1.7	1.0	-0.5	0.6	0.1	-1.2	-0.2	-1.3	0.1	0.2	0.9	-0.2	-0.6	0.2	0.6	0.4	0.5	-0.4
Lupus	0.2	0.3	1.6	1.3	0.3	-0.7	-0.4	-0.2	0.1	-0.6	0.1	0.0	-0.0	-0.9	0.2	-0.5	0.3	-0.2	0.2	-0.7
Height	0.2	3.1	10.4	2.3	-2.5	-1.6	-2.7	1.6	1.4	1.4	0.8	-1.3	1.0	-0.9	-0.7	-0.8	2.2	1.9	0.3	3.2
Ever had hysterectomy (womb removed)	0.2	0.2	1.5	0.0	0.1	-0.5	-0.5	0.2	-1.2	0.3	-0.1	-0.0	-0.2	-0.4	-0.4	0.3	-0.8	-0.6	-0.3	0.1
Medication: Ramipril	0.2	0.2	0.8	0.9	0.7	-0.1	-0.2	0.0	0.4	-0.4	0.2	0.3	0.7	0.2	0.7	0.3	0.5	0.9	-0.3	0.1
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	2.6	1.6	-0.9	-0.7	-0.5	0.7	-0.4	1.1	0.0	-0.5	0.5	0.1	-0.2	-0.3	1.3	0.9	0.5	-0.8
Medication: Amlodipine	0.2	0.3	1.8	0.8	0.1	0.2	0.1	0.8	-0.2	1.3	0.5	0.6	0.6	-0.3	0.3	0.2	-0.0	0.2	0.3	0.3
Medication: Allopurinol	0.2	0.3	1.1	-1.0	-0.3	-0.8	-0.8	-0.2	-0.7	0.2	-0.7	-0.7	-0.5	-0.4	-0.2	-0.5	-0.2	-0.4	-0.4	-0.1
Supplements: Vitamin C	0.2	0.3	1.2	-0.8	-0.4	0.5	0.5	-0.4	-0.0	-0.5	-0.3	0.0	-0.7	0.3	0.0	-0.0	-1.1	-0.8	-0.3	0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	1.1	0.3	-0.1	-0.4	-0.5	0.1	0.7	-0.2	-0.5	-0.4	0.1	-1.1	0.4	-0.1	-0.6	-0.2	-0.9	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	1.5	0.8	-0.5	-0.6	-0.8	0.3	-0.3	0.9	0.4	-0.2	0.3	0.1	-0.8	-0.3	1.2	1.0	0.9	1.0
High cholesterol (Self-reported)	0.2	0.3	1.1	0.9	0.1	-1.1	-0.3	0.5	0.6	-0.0	0.1	0.5	0.8	-0.8	0.5	0.8	0.5	0.4	0.3	-0.0
Medication: Atorvastatin	0.2	0.3	2.0	1.4	-0.3	0.1	-0.4	-0.1	-0.6	-0.8	-0.6	-0.6	0.0	-0.7	0.2	-0.5	0.4	-0.1	0.2	0.3
Blood Red Count	0.1	0.9	3.4	1.9	-0.2	-0.1	0.2	1.2	0.6	1.4	0.6	0.4	1.6	0.7	-0.0	0.7	1.3	1.5	0.4	-0.8
Tanning	0.1	1.1	5.0	-2.2	-1.5	-0.6	-0.5	1.4	1.1	0.9	1.1	0.0	-0.7	-0.4	-0.9	-0.4	-1.6	-0.9	0.4	0.8
Forced vital capacity (FVC)	0.1	0.5	2.3	0.6	-1.5	-0.4	-0.2	0.7	0.5	0.5	-0.7	-1.3	-0.5	0.2	-0.8	-0.9	-0.4	-0.3	-0.1	-1.1
Falls in the last year	0.1	0.2	0.4	-0.2	-0.1	0.7	-0.2	0.2	0.5	0.6	0.2	0.1	0.5	-0.6	0.5	0.4	0.0	0.2	0.4	-0.4
Standing height	0.1	1.3	3.9	1.7	-1.0	-0.6	-1.6	1.2	1.1	1.2	0.6	-0.7	0.5	-0.7	-0.9	-0.2	1.5	1.3	0.8	2.0
Comparative height size at age 10	0.1	0.7	2.1	0.9	-0.2	0.7	-0.5	-0.8	0.3	-1.1	-1.0	-1.1	-1.4	-0.6	-0.8	-1.0	-0.1	-0.8	-1.4	0.5
Hair Pigment	0.0	0.8	2.9	-0.5	0.1	0.8	1.7	0.2	1.7	-1.5	-0.1	0.4	-0.5	0.7	1.2	0.1	-1.3	-1.1	-0.2	-0.2

Hub : Genes

CYP2D7P1

Models

Trait associations