[Hub]/) : Traits : Systolic Blood Pressure :

chr3:10,617,048-13,321,852

Best TWAS P=1.05e-18 · Best GWAS P=7.97e-20 conditioned to 0.00481

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ATG7 0.07 0.07 lasso 3 0.07 3.3e-09 -7.9 8.6 7.0e-18 -0.82 0.12 0.88 FALSE
2 CommonMind Brain Pre-frontal Cortex VGLL4 0.04 0.02 blup 511 0.02 7.8e-04 -9.1 -8.8 1.0e-18 0.83 0.02 0.96 TRUE
3 GTEx Adipose Subcutaneous ATG7 0.10 0.01 enet 24 0.03 2.0e-03 -8.1 5.5 4.8e-08 -0.50 0.15 0.51 FALSE
4 GTEx Adipose Visceral Omentum ATG7 0.18 0.06 lasso 4 0.06 2.9e-04 -8.2 8.3 1.2e-16 -0.81 0.22 0.72 FALSE
5 GTEx Cells EBV-transformed lymphocytes ATG7 0.39 0.12 lasso 6 0.17 3.4e-06 -3.3 6.2 7.0e-10 -0.62 0.51 0.35 FALSE
6 GTEx Cells Transformed fibroblasts ATG7 0.26 0.10 enet 13 0.17 6.8e-13 -4.0 6.8 1.4e-11 -0.63 0.96 0.04 FALSE
7 GTEx Muscle Skeletal ATG7 0.06 0.02 lasso 4 0.03 8.6e-04 -8.8 8.8 1.5e-18 -0.86 0.04 0.93 FALSE
8 GTEx Testis VGLL4 0.18 -0.01 lasso 3 -0.01 6.9e-01 -7.9 -7.5 4.3e-14 0.65 0.05 0.23 FALSE
9 ROSMAP Brain Pre-frontal Cortex MKRN2 0.16 0.05 lasso 10 0.08 1.8e-10 -5.3 -5.3 1.0e-07 0.04 0.00 0.99 TRUE
10 ROSMAP Brain Pre-frontal Cortex VGLL4 0.05 0.03 blup 422 0.04 3.7e-06 -6.4 -6.0 2.1e-09 0.68 0.55 0.42 FALSE
11 ROSMAP Brain Pre-frontal Cortex ATG7 0.06 0.05 lasso 3 0.04 2.4e-06 -7.9 8.0 1.3e-15 -0.66 0.26 0.73 FALSE
12 YFS Blood VGLL4 0.05 0.01 blup 507 0.02 4.0e-08 -3.3 -5.7 1.5e-08 0.46 0.34 0.65 FALSE
13 The Cancer Genome Atlas Bladder Urothelial Carcinoma ATG7 0.06 0.01 lasso 2 0.02 1.2e-02 -4.3 7.0 2.4e-12 -0.67 0.15 0.22 FALSE
14 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ATG7 0.05 0.05 lasso 4 0.03 3.2e-04 -8.0 7.9 3.8e-15 -0.70 0.07 0.86 FALSE
15 The Cancer Genome Atlas Brain Lower Grade Glioma ATG7 0.07 0.00 blup 137 0.03 1.9e-04 -8.9 6.6 5.3e-11 -0.51 0.02 0.80 FALSE