[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr3:10,617,048-13,321,852

Best TWAS P=1.05e-18 · Best GWAS P=7.97e-20 conditioned to 0.00481

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ATG7	0.07	0.07	lasso	3	0.07	3.3e-09	-7.9	8.6	7.0e-18	-0.82	0.12	0.88	FALSE
2	CommonMind	Brain Pre-frontal Cortex	VGLL4	0.04	0.02	blup	511	0.02	7.8e-04	-9.1	-8.8	1.0e-18	0.83	0.02	0.96	TRUE
3	GTEx	Adipose Subcutaneous	ATG7	0.10	0.01	enet	24	0.03	2.0e-03	-8.1	5.5	4.8e-08	-0.50	0.15	0.51	FALSE
4	GTEx	Adipose Visceral Omentum	ATG7	0.18	0.06	lasso	4	0.06	2.9e-04	-8.2	8.3	1.2e-16	-0.81	0.22	0.72	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	ATG7	0.39	0.12	lasso	6	0.17	3.4e-06	-3.3	6.2	7.0e-10	-0.62	0.51	0.35	FALSE
6	GTEx	Cells Transformed fibroblasts	ATG7	0.26	0.10	enet	13	0.17	6.8e-13	-4.0	6.8	1.4e-11	-0.63	0.96	0.04	FALSE
7	GTEx	Muscle Skeletal	ATG7	0.06	0.02	lasso	4	0.03	8.6e-04	-8.8	8.8	1.5e-18	-0.86	0.04	0.93	FALSE
8	GTEx	Testis	VGLL4	0.18	-0.01	lasso	3	-0.01	6.9e-01	-7.9	-7.5	4.3e-14	0.65	0.05	0.23	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	MKRN2	0.16	0.05	lasso	10	0.08	1.8e-10	-5.3	-5.3	1.0e-07	0.04	0.00	0.99	TRUE
10	ROSMAP	Brain Pre-frontal Cortex	VGLL4	0.05	0.03	blup	422	0.04	3.7e-06	-6.4	-6.0	2.1e-09	0.68	0.55	0.42	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	ATG7	0.06	0.05	lasso	3	0.04	2.4e-06	-7.9	8.0	1.3e-15	-0.66	0.26	0.73	FALSE
12	YFS	Blood	VGLL4	0.05	0.01	blup	507	0.02	4.0e-08	-3.3	-5.7	1.5e-08	0.46	0.34	0.65	FALSE
13	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ATG7	0.06	0.01	lasso	2	0.02	1.2e-02	-4.3	7.0	2.4e-12	-0.67	0.15	0.22	FALSE
14	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ATG7	0.05	0.05	lasso	4	0.03	3.2e-04	-8.0	7.9	3.8e-15	-0.70	0.07	0.86	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	ATG7	0.07	0.00	blup	137	0.03	1.9e-04	-8.9	6.6	5.3e-11	-0.51	0.02	0.80	FALSE