Best TWAS P=1.4e-08 · Best GWAS P=7.18e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | PCCB | 0.07 | 0.05 | enet | 4 | 0.02 | 0.0066 | -5.8 | 5.6 | 2.8e-08 | -0.98 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Brain Frontal Cortex BA9 | PCCB | 0.11 | 0.01 | enet | 9 | 0.01 | 0.1650 | -5.8 | 5.2 | 2.0e-07 | -0.96 | 0.02 | 0.88 | FALSE |
| 3 | GTEx | Breast Mammary Tissue | PCCB | 0.08 | 0.05 | lasso | 3 | 0.03 | 0.0131 | -5.8 | 5.7 | 1.4e-08 | -0.99 | 0.01 | 0.97 | TRUE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | MSL2 | 0.04 | 0.02 | blup | 35 | 0.01 | 0.0187 | 4.3 | 5.3 | 1.1e-07 | -0.92 | 0.01 | 0.87 | FALSE |