Best TWAS P=1.87e-11 · Best GWAS P=5.94e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | MRAS | 0.52 | 0.53 | lasso | 5 | 0.54 | 2.5e-34 | 6.4 | 6.4 | 1.6e-10 | 1.00 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Coronary | MRAS | 0.32 | 0.10 | lasso | 4 | 0.12 | 7.4e-05 | 6.3 | 5.8 | 7.0e-09 | 0.94 | 0.01 | 0.98 | FALSE |
| 3 | GTEx | Artery Tibial | MRAS | 0.24 | 0.20 | enet | 7 | 0.20 | 2.3e-15 | 6.4 | 6.7 | 1.9e-11 | 0.97 | 0.00 | 1.00 | TRUE |
| 4 | GTEx | Brain Frontal Cortex BA9 | DBR1 | 0.18 | 0.10 | lasso | 5 | 0.11 | 9.7e-04 | 6.3 | 6.4 | 1.9e-10 | 0.96 | 0.02 | 0.92 | FALSE |