Best TWAS P=7.95e-08 · Best GWAS P=7.6e-11 conditioned to 4.44e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CCDC158 | 0.26 | 0.15 | lasso | 6 | 0.20 | 1.8e-24 | 5.1 | 5.3 | 9.7e-08 | 0.62 | 0.95 | 0.05 | FALSE |
2 | ROSMAP | Brain Pre-frontal Cortex | CCDC158 | 0.13 | 0.10 | lasso | 4 | 0.13 | 2.1e-16 | 5.1 | 5.4 | 8.0e-08 | 0.61 | 0.94 | 0.06 | TRUE |