Best TWAS P=1.01e-39 · Best GWAS P=5.31e-115 conditioned to 7.05e-20
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C4orf22 | 0.09 | 0.08 | lasso | 5 | 0.07 | 4.5e-09 | 12.2 | 13.2 | 1.0e-39 | 0.59 | 1.00 | 0.00 | TRUE |
| 2 | CommonMind | Brain Pre-frontal Cortex | FGF5 | 0.07 | 0.06 | lasso | 2 | 0.05 | 5.4e-07 | 12.2 | 10.9 | 8.9e-28 | 0.53 | 0.76 | 0.14 | TRUE |
| 3 | GTEx | Adipose Visceral Omentum | PRDM8 | 0.29 | 0.01 | lasso | 3 | 0.01 | 1.2e-01 | -6.4 | -5.7 | 1.0e-08 | -0.18 | 0.09 | 0.06 | FALSE |
| 4 | GTEx | Breast Mammary Tissue | PRDM8 | 0.23 | 0.06 | lasso | 6 | 0.05 | 9.5e-04 | -5.6 | -5.2 | 2.1e-07 | -0.21 | 0.44 | 0.02 | TRUE |
| 5 | GTEx | Nerve Tibial | PRDM8 | 0.14 | 0.14 | lasso | 3 | 0.13 | 1.0e-09 | -6.4 | -6.4 | 1.3e-10 | -0.19 | 1.00 | 0.00 | FALSE |