Best TWAS P=4.73e-14 · Best GWAS P=1.2e-17 conditioned to 5.27e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Testis | CACNA2D4 | 0.19 | 0.04 | lasso | 5 | 0.01 | 9.2e-02 | 8.4 | -7.5 | 4.7e-14 | -0.87 | 0.03 | 0.66 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | DCP1B | 0.08 | 0.00 | blup | 553 | 0.04 | 1.8e-05 | 3.6 | -5.6 | 2.7e-08 | -0.30 | 0.08 | 0.20 | FALSE |