Best TWAS P=7.56e-09 · Best GWAS P=3.74e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | PSMA4 | 0.08 | 0.08 | lasso | 10 | 0.11 | 8.3e-35 | 3.5 | 5.3 | 1.4e-07 | -0.72 | 0.83 | 0.16 | FALSE |
| 2 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | CHRNA5 | 0.15 | 0.07 | blup | 50 | 0.09 | 2.5e-04 | -5.6 | -5.8 | 7.6e-09 | 0.95 | 0.01 | 0.97 | TRUE |