[Hub]/) : Traits : Schizophrenia (2014) :

chr14:103,161,201-105,211,221

Best TWAS P=3.79e-12 · Best GWAS P=4.93e-12 conditioned to 0.234

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PPP1R13B 0.04 0.02 lasso 2 0.01 4.1e-02 5.2 -5.3 1.1e-07 -0.63 0.20 0.30 FALSE
2 GTEx Adipose Subcutaneous KLC1 0.05 0.03 lasso 3 0.03 1.8e-03 6.9 6.0 2.3e-09 0.86 0.02 0.94 FALSE
3 GTEx Adipose Subcutaneous XRCC3 0.09 0.08 lasso 5 0.07 3.8e-06 6.5 6.5 7.5e-11 0.95 0.01 0.99 FALSE
4 GTEx Adipose Subcutaneous APOPT1 0.06 0.02 lasso 5 0.02 8.2e-03 5.5 -6.5 8.9e-11 -0.91 0.03 0.93 FALSE
5 GTEx Adipose Subcutaneous RP11-73M18.8 0.14 0.19 lasso 4 0.20 6.4e-16 5.5 5.7 1.5e-08 0.86 0.06 0.94 FALSE
6 GTEx Adrenal Gland KLC1 0.15 0.03 lasso 3 0.06 4.6e-03 6.0 5.7 9.7e-09 0.80 0.06 0.66 FALSE
7 GTEx Artery Aorta ZFYVE21 0.10 0.09 lasso 4 0.08 2.9e-05 5.6 5.2 1.8e-07 0.64 0.26 0.15 FALSE
8 GTEx Artery Tibial XRCC3 0.06 0.08 lasso 3 0.03 1.4e-03 5.3 5.7 1.2e-08 0.74 0.70 0.23 FALSE
9 GTEx Artery Tibial RP11-73M18.8 0.09 0.06 lasso 4 0.09 7.4e-08 5.5 5.7 9.3e-09 0.82 0.04 0.96 FALSE
10 GTEx Artery Tibial RP11-73M18.6 0.05 0.03 lasso 2 0.02 4.7e-03 5.5 5.4 8.6e-08 0.83 0.03 0.88 FALSE
11 GTEx Brain Cortex XRCC3 0.12 0.02 lasso 4 0.01 1.7e-01 5.2 5.6 2.9e-08 0.74 0.11 0.42 FALSE
12 GTEx Brain Cortex RP11-73M18.8 0.35 0.13 enet 34 0.25 1.2e-07 6.5 5.8 7.9e-09 0.66 0.02 0.98 FALSE
13 GTEx Brain Nucleus accumbens basal ganglia TDRD9 0.23 0.02 lasso 3 0.05 1.5e-02 5.4 -5.2 2.0e-07 -0.62 0.08 0.24 FALSE
14 GTEx Breast Mammary Tissue KLC1 0.12 0.02 enet 26 0.07 2.9e-04 5.4 6.2 4.1e-10 0.82 0.06 0.93 FALSE
15 GTEx Breast Mammary Tissue XRCC3 0.15 0.01 enet 37 0.01 1.0e-01 6.0 5.3 1.5e-07 0.66 0.16 0.81 FALSE
16 GTEx Breast Mammary Tissue RP11-73M18.8 0.19 0.14 enet 21 0.26 2.0e-13 6.9 6.0 1.6e-09 0.85 0.00 1.00 FALSE
17 GTEx Breast Mammary Tissue (Male) RP11-73M18.8 0.22 0.12 lasso 4 0.08 7.3e-03 6.0 5.8 5.3e-09 0.74 0.07 0.79 FALSE
18 GTEx Breast Mammary Tissue (Female) KLC1 0.09 0.00 lasso 2 0.00 2.4e-01 6.9 6.9 3.8e-12 0.93 0.03 0.72 TRUE
19 GTEx Breast Mammary Tissue (Female) RP11-73M18.8 0.21 0.09 enet 12 0.16 1.3e-05 -3.2 5.1 3.0e-07 0.73 0.03 0.96 FALSE
20 GTEx Cells EBV-transformed lymphocytes PPP1R13B 0.15 0.08 lasso 4 0.07 2.2e-03 5.4 -6.5 8.7e-11 -0.71 0.18 0.60 FALSE
21 GTEx Cells Transformed fibroblasts APOPT1 0.14 0.12 lasso 3 0.10 6.4e-08 -4.1 -5.2 1.5e-07 -0.60 0.96 0.04 FALSE
22 GTEx Colon Transverse KLC1 0.16 0.01 lasso 7 0.00 1.9e-01 6.9 6.7 2.6e-11 0.95 0.01 0.91 FALSE
23 GTEx Colon Transverse XRCC3 0.13 0.14 lasso 4 0.11 1.0e-05 6.1 6.0 1.5e-09 0.81 0.15 0.84 FALSE
24 GTEx Colon Transverse BAG5 0.14 0.05 lasso 10 0.02 4.8e-02 6.5 5.5 3.1e-08 0.88 0.01 0.95 FALSE
25 GTEx Esophagus Gastroesophageal Junction PPP1R13B 0.09 0.08 lasso 2 0.05 7.9e-03 5.6 -5.5 3.0e-08 -0.67 0.13 0.56 FALSE
26 GTEx Esophagus Gastroesophageal Junction RP11-73M18.8 0.14 0.07 enet 10 0.10 2.4e-04 5.5 5.7 9.5e-09 0.79 0.11 0.82 FALSE
27 GTEx Esophagus Mucosa KLC1 0.17 0.09 lasso 5 0.12 1.6e-08 6.0 5.9 4.9e-09 0.75 0.56 0.42 FALSE
28 GTEx Esophagus Mucosa XRCC3 0.12 0.15 lasso 2 0.13 4.4e-09 6.0 6.1 1.2e-09 0.82 0.49 0.51 FALSE
29 GTEx Esophagus Muscularis PPP1R13B 0.12 0.07 lasso 5 0.07 3.9e-05 5.2 -5.6 2.8e-08 -0.67 0.94 0.05 FALSE
30 GTEx Esophagus Muscularis KLC1 0.07 0.01 enet 10 0.02 2.6e-02 -3.9 6.4 1.6e-10 0.68 0.13 0.39 FALSE
31 GTEx Esophagus Muscularis XRCC3 0.11 0.05 enet 23 0.03 5.2e-03 5.5 5.7 1.3e-08 0.66 0.02 0.92 FALSE
32 GTEx Esophagus Muscularis RP11-73M18.8 0.11 0.04 enet 11 0.10 1.9e-06 6.0 5.5 4.5e-08 0.69 0.15 0.77 FALSE
33 GTEx Muscle Skeletal KLC1 0.11 0.07 lasso 7 0.08 3.3e-08 -3.9 5.7 1.1e-08 0.73 0.42 0.58 FALSE
34 GTEx Muscle Skeletal RP11-73M18.8 0.11 0.14 lasso 7 0.13 8.4e-13 4.4 5.5 4.6e-08 0.71 0.70 0.30 FALSE
35 GTEx Nerve Tibial KLC1 0.07 0.00 enet 22 0.01 8.5e-02 5.0 6.1 8.2e-10 0.73 0.08 0.74 FALSE
36 GTEx Nerve Tibial XRCC3 0.08 0.06 lasso 3 0.05 3.5e-04 5.5 5.8 6.4e-09 0.85 0.05 0.95 FALSE
37 GTEx Nerve Tibial APOPT1 0.10 0.08 lasso 5 0.06 7.8e-05 6.8 -6.7 1.8e-11 -0.98 0.00 0.99 FALSE
38 GTEx Nerve Tibial RP11-73M18.8 0.08 0.13 lasso 4 0.10 7.4e-08 5.5 5.5 4.8e-08 0.84 0.14 0.86 FALSE
39 GTEx Ovary RP11-73M18.8 0.19 0.20 lasso 5 0.14 2.4e-04 5.5 5.6 1.7e-08 0.80 0.08 0.68 FALSE
40 GTEx Pituitary RP11-73M18.8 0.23 0.17 lasso 2 0.13 3.6e-04 5.5 5.5 3.4e-08 0.85 0.06 0.64 FALSE
41 GTEx Prostate RP11-73M18.8 0.15 0.29 lasso 1 0.25 5.2e-07 6.0 6.0 1.6e-09 0.82 0.09 0.80 FALSE
42 GTEx Skin Not Sun Exposed Suprapubic KLC1 0.11 0.09 lasso 4 0.10 4.1e-06 5.4 6.1 9.8e-10 0.64 0.40 0.46 FALSE
43 GTEx Skin Not Sun Exposed Suprapubic XRCC3 0.14 0.03 lasso 14 0.03 1.3e-02 6.0 6.6 4.9e-11 0.80 0.07 0.92 FALSE
44 GTEx Skin Sun Exposed Lower leg KLC1 0.06 0.09 enet 19 0.08 2.2e-07 5.5 5.3 1.1e-07 0.79 0.14 0.85 FALSE
45 GTEx Skin Sun Exposed Lower leg XRCC3 0.09 0.10 enet 16 0.09 6.3e-08 5.9 5.4 5.4e-08 0.76 0.45 0.55 FALSE
46 GTEx Spleen KLC1 0.15 0.05 lasso 3 0.03 6.4e-02 4.0 5.5 4.6e-08 0.81 0.03 0.68 FALSE
47 GTEx Spleen XRCC3 0.28 0.19 lasso 3 0.24 8.7e-07 6.0 5.6 2.8e-08 0.77 0.03 0.96 FALSE
48 GTEx Testis KLC1 0.17 0.17 lasso 2 0.15 4.4e-07 6.0 6.3 4.1e-10 0.82 0.37 0.58 FALSE
49 GTEx Testis RP11-73M18.8 0.16 0.12 lasso 4 0.12 4.0e-06 6.0 6.1 1.1e-09 0.82 0.30 0.65 FALSE
50 GTEx Thyroid KLC1 0.12 0.03 enet 22 0.03 3.6e-03 4.9 5.7 1.3e-08 0.61 0.18 0.61 FALSE
51 GTEx Thyroid APOPT1 0.11 0.12 lasso 1 0.10 1.9e-08 6.5 -6.5 7.0e-11 -0.97 0.01 0.99 FALSE
52 GTEx Whole Blood KLC1 0.16 0.13 lasso 3 0.11 3.6e-10 6.0 6.1 1.1e-09 0.83 0.30 0.70 FALSE
53 GTEx Whole Blood XRCC3 0.08 0.12 lasso 3 0.10 1.3e-09 6.0 6.1 9.9e-10 0.82 0.44 0.56 FALSE
54 METSIM Adipose MARK3 0.03 0.02 lasso 6 0.03 6.3e-05 6.5 -5.8 5.2e-09 -0.87 0.08 0.92 FALSE
55 METSIM Adipose TDRD9 0.08 0.04 lasso 10 0.06 1.9e-09 6.8 -6.0 2.0e-09 -0.81 0.00 1.00 FALSE
56 METSIM Adipose XRCC3 0.13 0.20 lasso 7 0.22 6.2e-33 6.1 5.5 4.0e-08 0.76 0.48 0.52 FALSE
57 YFS Blood BAG5 0.01 0.01 bslmm 350 0.00 1.9e-02 6.9 6.0 1.7e-09 0.73 0.01 0.96 FALSE
58 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma XRCC3 0.03 0.04 enet 3 0.04 6.1e-05 6.0 6.1 9.0e-10 0.82 0.01 0.99 FALSE
59 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma XRCC3 0.06 0.07 lasso 4 0.05 4.6e-04 6.1 5.8 5.3e-09 0.80 0.01 0.92 FALSE
60 The Cancer Genome Atlas Brain Lower Grade Glioma C14orf153 0.04 0.01 blup 38 0.03 6.2e-04 6.9 -6.1 1.4e-09 -0.84 0.00 0.95 FALSE
61 The Cancer Genome Atlas Lung Adenocarcinoma C14orf153 0.06 0.02 blup 38 0.04 2.4e-05 -3.5 -5.6 2.5e-08 -0.79 0.02 0.94 FALSE
62 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CKB 0.03 0.00 blup 34 0.02 1.4e-03 6.5 -5.3 1.4e-07 -0.80 0.01 0.88 FALSE
63 The Cancer Genome Atlas Pancreatic Adenocarcinoma C14orf153 0.15 0.03 blup 37 0.03 1.6e-02 5.5 -6.2 7.1e-10 -0.91 0.01 0.78 FALSE
64 The Cancer Genome Atlas Prostate Adenocarcinoma CKB 0.07 0.09 blup 32 0.10 1.1e-10 4.0 -5.5 4.1e-08 -0.83 0.14 0.86 FALSE
65 The Cancer Genome Atlas Prostate Adenocarcinoma XRCC3 0.02 0.01 blup 46 0.01 3.0e-02 4.2 5.2 1.8e-07 0.67 0.03 0.42 FALSE
66 The Cancer Genome Atlas Thyroid Carcinoma KLC1 0.04 0.01 blup 82 0.03 5.4e-04 6.8 6.3 3.3e-10 0.86 0.02 0.89 FALSE
67 The Cancer Genome Atlas Thyroid Carcinoma PPP1R13B 0.04 0.04 lasso 2 0.03 7.9e-04 6.0 6.1 1.4e-09 0.73 0.02 0.96 FALSE
68 The Cancer Genome Atlas Thyroid Carcinoma XRCC3 0.08 0.07 lasso 4 0.08 1.8e-08 6.1 5.6 2.3e-08 0.76 0.01 0.99 FALSE