Best TWAS P=1.56e-08 · Best GWAS P=1.79e-07 conditioned to 0.0049
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CPNE7 | 0.09 | 0.02 | bslmm | 452 | 0.04 | 1.4e-05 | 4.0 | -5.7 | 1.6e-08 | 0.49 | 0.26 | 0.63 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SPG7 | 0.09 | 0.06 | lasso | 3 | 0.02 | 3.5e-02 | -5.2 | -5.2 | 2.4e-07 | 0.93 | 0.00 | 0.92 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SPG7 | 0.07 | 0.03 | enet | 11 | 0.04 | 3.7e-05 | -5.2 | -5.3 | 9.9e-08 | 0.84 | 0.00 | 0.99 | FALSE |