[Hub]/) : Traits : Schizophrenia (2014) :

chr17:17,017,584-18,325,085

Best TWAS P=1.9e-08 · Best GWAS P=2.55e-08 conditioned to 0.36

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous TOM1L2 0.04 0.04 lasso 3 0.04 5.3e-04 5.1 -5.3 1.2e-07 -0.92 0.13 0.85 FALSE
2 GTEx Adipose Visceral Omentum TOM1L2 0.15 0.13 lasso 4 0.11 3.6e-06 5.2 -5.3 1.3e-07 -0.87 0.14 0.86 FALSE
3 GTEx Esophagus Muscularis TOM1L2 0.06 0.07 enet 12 0.05 4.3e-04 5.2 -5.4 5.8e-08 -0.92 0.09 0.90 FALSE
4 GTEx Muscle Skeletal TOM1L2 0.08 0.11 lasso 6 0.10 5.3e-10 5.1 -5.2 1.8e-07 -0.86 0.20 0.80 FALSE
5 GTEx Muscle Skeletal AC122129.1 0.13 0.14 lasso 4 0.13 7.3e-13 5.1 -5.3 9.7e-08 -0.89 0.11 0.89 FALSE
6 GTEx Whole Blood SREBF1 0.04 0.06 lasso 5 0.05 2.4e-05 5.3 -5.3 1.2e-07 -0.89 0.15 0.85 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma TOM1L2 0.01 0.01 blup 83 0.01 1.8e-03 4.8 -5.6 2.7e-08 -0.92 0.08 0.76 FALSE
8 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma LRRC48 0.07 0.05 enet 12 0.04 7.0e-03 5.3 5.6 1.9e-08 0.93 0.03 0.70 TRUE
9 The Cancer Genome Atlas Thyroid Carcinoma C17orf39 0.05 0.05 blup 49 0.05 5.8e-06 5.4 5.6 2.6e-08 0.98 0.02 0.97 FALSE