Best TWAS P=5.47e-08 · Best GWAS P=6.97e-07 conditioned to 0.437
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | PABPC4 | 0.10 | 0.10 | lasso | 4 | 0.10 | 3.4e-08 | 5.0 | -5.1 | 2.9e-07 | -0.99 | 0.00 | 0.99 | FALSE |
| 2 | GTEx | Artery Tibial | RP11-69E11.8 | 0.05 | 0.02 | lasso | 2 | 0.02 | 6.3e-03 | 4.3 | -5.2 | 2.5e-07 | -0.48 | 0.06 | 0.72 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | PABPC4 | 0.11 | 0.09 | lasso | 7 | 0.08 | 2.7e-07 | 4.7 | -5.1 | 2.7e-07 | -0.96 | 0.01 | 0.99 | FALSE |
| 4 | YFS | Blood | PABPC4 | 0.04 | 0.03 | enet | 44 | 0.03 | 3.2e-11 | 4.7 | -5.4 | 5.5e-08 | -0.83 | 0.01 | 0.98 | TRUE |