Best TWAS P=4.9e-09 · Best GWAS P=6.55e-10 conditioned to 0.0471
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Not Sun Exposed Suprapubic | KIF5A | 0.13 | 0.00 | enet | 9 | 0.03 | 0.0067 | -6.2 | -5.1 | 2.8e-07 | 0.88 | 0.01 | 0.98 | FALSE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | INHBC | 0.03 | 0.03 | lasso | 3 | 0.02 | 0.0016 | -6.2 | 5.9 | 4.9e-09 | -0.94 | 0.00 | 0.98 | TRUE |