Best TWAS P=5.56e-14 · Best GWAS P=1.15e-12 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | NLRC5 | 0.38 | 0.24 | lasso | 4 | 0.30 | 5.0e-23 | -7.0 | 6.2 | 6.8e-10 | -0.92 | 0.00 | 1.00 | FALSE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | CETP | 0.11 | 0.03 | blup | 90 | 0.05 | 1.2e-03 | 2.8 | 5.5 | 3.2e-08 | -0.45 | 0.02 | 0.56 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CETP | 0.05 | 0.03 | enet | 10 | 0.03 | 2.7e-04 | -6.7 | 6.1 | 8.7e-10 | -0.79 | 0.00 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | CETP | 0.21 | 0.19 | lasso | 3 | 0.18 | 2.6e-10 | -7.2 | 7.5 | 5.6e-14 | -0.99 | 0.00 | 1.00 | TRUE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | CETP | 0.06 | 0.04 | lasso | 1 | 0.04 | 2.8e-05 | -6.9 | 6.9 | 5.2e-12 | -0.72 | 0.02 | 0.97 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CETP | 0.07 | 0.08 | lasso | 1 | 0.07 | 7.8e-08 | -6.9 | 6.9 | 5.2e-12 | -0.72 | 0.02 | 0.98 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | HERPUD1 | 0.06 | 0.02 | blup | 80 | 0.05 | 2.8e-05 | 3.4 | 5.7 | 1.5e-08 | -0.63 | 0.08 | 0.58 | FALSE |