Hub : Genes

HERPUD1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Breast Mammary Tissue 0.1850 0.0670 7.3e-03 0.005 NA -0.006 NA 0.000 1.6e-01 NA 9.3e-01 NA 3.1e-01
2 GTEx Breast Mammary Tissue (Female) 0.1410 0.0942 1.1e-01 0.028 NA 0.001 NA -0.006 4.9e-02 NA 3.1e-01 NA 5.1e-01
3 METSIM Adipose 0.0586 0.0205 9.8e-04 0.047 0.029 0.029 0.029 0.038 1.4e-07 2.6e-05 2.7e-05 2.7e-05 1.9e-06
4 NTR Blood 0.0234 0.0085 1.2e-03 0.000 0.009 -0.001 0.007 -0.001 3.5e-01 4.7e-04 6.6e-01 1.5e-03 7.9e-01
5 YFS Blood 0.0973 0.0161 0.0e+00 0.064 0.086 0.079 0.083 0.071 4.7e-20 1.3e-26 1.8e-24 1.1e-25 2.9e-22
6 TCGA Head and Neck Squamous Cell Carcinoma 0.0310 0.0160 9.6e-03 0.017 0.016 0.004 NA 0.009 4.2e-03 5.2e-03 9.5e-02 NA 3.1e-02
7 TCGA Prostate Adenocarcinoma 0.1417 0.0509 7.3e-06 0.073 0.051 0.057 NA 0.061 4.5e-08 4.9e-06 1.3e-06 NA 6.0e-07
8 TCGA Thyroid Carcinoma 0.0630 0.0270 2.4e-04 0.019 0.046 0.013 NA 0.023 5.2e-03 2.8e-05 1.6e-02 NA 2.5e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.9 1.4 4.6 -1.2 0.0 -1.1 -0.2 -0.9 -1.7 2.1 -0.4
Bipolar Disorder or Schizophrenia 0.2 0.6 1.7 -1.0 0.0 0.0 -0.3 -1.3 -1.2 0.8 -0.1
Depressed Affect (Nagel 2018) 0.5 1.1 3.0 0.8 0.0 -0.8 -0.5 1.7 -1.2 1.6 0.0
Depression (Nagel 2018) 0.3 0.5 2.3 0.5 0.0 0.5 -1.5 0.8 -0.4 0.2 0.8
Intelligence (Savage-Jansen 2018) 0.2 0.7 2.8 0.9 0.0 -0.6 1.3 1.7 -0.1 0.6 -0.1
Neuroticism (Nagel 2018) 0.5 1.1 4.1 1.2 0.0 -0.6 0.2 2.0 -1.2 1.2 -0.3
Schizophrenia (2018) 0.1 0.3 0.9 -0.3 0.0 0.9 -0.2 -1.0 -0.1 -0.7 0.2
Schizophrenia vs Biploar Disorder 0.7 0.9 2.4 -1.3 0.0 1.2 0.3 -0.3 1.6 0.0 1.2
Worry (Nagel 2018) 0.3 0.7 5.3 0.1 0.0 0.3 0.4 2.3 0.2 -0.1 0.5
Alzheimer’s Disease (in mother) 0.1 0.1 0.3 0.2 0.0 0.3 -0.5 0.3 -0.4 -0.4 -0.4
Alzheimer’s Disease (in father) 0.6 0.7 1.9 1.4 0.0 1.3 0.1 0.5 -0.1 -1.2 -0.1
Alzheimer’s Disease (including proxy) 0.4 0.5 1.5 0.8 0.0 1.2 -0.5 0.6 -0.5 -1.2 -0.2
Crohns Disease (2017) 0.3 0.8 1.4 1.0 0.0 1.1 -0.3 1.2 1.1 -0.9 0.6
Irritable Bowel Disease (IBD) 0.8 2.0 4.0 -0.0 0.0 2.0 -0.5 1.8 1.9 -1.9 1.0
Ulcerative Colitis (UC) 1.2 2.2 5.9 -0.5 0.0 2.2 -1.0 1.0 2.1 -2.4 0.8
Major Depression (MDD) 0.4 0.5 3.0 -1.7 0.0 -0.0 -0.0 -0.7 -0.1 0.2 -0.8
Reaction Time 0.1 0.2 0.8 -0.1 0.0 0.1 0.9 0.3 -0.7 -0.7 -0.4
Verbal and Numeric Reasoning (VNR) 0.4 0.9 2.2 1.5 0.0 0.4 0.6 1.2 1.2 -0.1 1.3
Breast Cancer 0.6 1.5 3.3 -0.3 0.0 1.5 1.2 0.3 1.8 -1.4 1.6
Ovarian Cancer 1.9 2.5 5.0 0.9 0.0 1.5 1.8 2.0 2.2 -1.1 1.9
Prostate Cancer 2.7 3.8 8.0 0.6 0.0 2.8 0.3 2.2 2.1 -2.4 2.6
Age at First Birth 1.7 2.5 5.6 -0.4 0.0 -2.3 -0.6 0.6 -2.4 1.9 -2.2
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.2 0.3 0.8 -0.9 0.0 0.3 -0.3 -0.9 0.5 -0.6 -0.4
Coronary Artery Disease (CAD) 0.7 0.8 2.8 -0.6 0.0 0.6 1.1 0.3 1.2 0.0 1.7
Crohns Disease (2012) 0.5 0.8 4.0 1.3 0.0 0.0 0.9 2.0 -0.1 0.1 -0.0
Mean Putamen Volume 0.5 0.6 2.0 0.5 0.0 -1.0 -0.0 -1.2 -0.2 0.4 -1.4
Fasting Glucose 0.3 0.4 1.6 -1.3 0.0 0.2 0.2 -0.8 0.5 0.5 -0.1
HbA1C 0.5 0.6 2.1 -1.1 0.0 -0.9 0.3 -1.4 -0.3 -0.3 0.4
HDL Cholesterol 135.1 225.5 756.2 1.8 0.0 -13.9 -12.7 -12.2 -22.8 4.6 -27.5
LDL Cholesterol 4.4 7.0 20.0 -1.2 0.0 3.2 1.1 0.9 4.4 -1.7 4.5
Lupus 1.4 2.1 5.1 1.7 0.0 1.6 -0.2 0.8 2.3 -1.0 2.1
Neuroticism (2016) 0.2 0.3 1.3 1.1 0.0 -0.0 -0.0 0.7 -0.1 0.3 0.8
Primary Biliary Cirrhosis 0.6 0.9 6.6 0.1 0.0 -0.5 -2.6 -0.3 0.0 0.3 -0.4
Rheumatoid Arthritis 0.3 0.4 1.7 -0.4 0.0 -0.6 -0.2 0.5 -0.9 1.3 0.6
Schizophrenia (2014) 0.1 0.2 1.2 -1.1 0.0 0.5 0.3 0.0 0.3 0.0 0.0
Triglycerides 6.3 10.4 32.0 -0.1 0.0 3.2 2.4 3.2 4.7 -1.4 5.7
Type 2 Diabetes (T2D) (2012) 0.3 0.3 1.5 -0.3 0.0 0.7 -0.1 1.2 0.8 0.0 -0.1
Ulcerative Colitis 0.3 0.4 1.9 -0.6 0.0 1.0 -0.1 1.4 0.3 0.0 0.2
Blood Eosinophil Count 0.3 2.7 11.8 2.8 0.0 -0.2 -3.4 0.9 0.8 -0.2 -0.3
Blood Platelet Count 0.0 0.4 0.9 0.2 0.0 -0.5 -0.9 -0.3 -0.8 0.3 -0.9
Blood Red Count 0.3 2.5 6.1 0.5 0.0 -2.5 0.5 -0.4 -2.3 1.9 -2.1
Blood White Count 0.7 5.0 12.5 0.1 0.0 2.8 2.0 3.5 2.2 -2.0 2.5
Heel T-Score 0.7 5.2 11.7 -0.6 0.0 -3.4 0.1 -2.5 -3.3 3.0 -1.7
BMI 0.2 1.2 2.5 -0.8 0.0 1.6 -0.7 -0.9 1.4 -1.2 1.5
Height 0.3 6.3 21.4 -1.0 0.0 -3.3 3.1 1.4 -1.4 4.6 1.8
Waist Hip Ratio (WHR) 0.5 2.1 7.8 0.5 0.0 1.8 -0.7 0.2 1.9 -1.1 2.8
Systolic Blood Pressure 0.9 4.6 12.5 -0.1 0.0 2.9 0.7 -0.2 3.5 -2.3 3.2
Smoking Status 0.6 1.3 2.7 1.6 0.0 1.5 0.5 1.2 1.0 -1.1 1.3
Allergy or Eczema 0.3 0.7 2.3 0.6 0.0 0.0 -1.5 -1.0 0.1 -1.1 -0.6
Cardiovascular Disease 1.3 4.4 8.6 -1.9 0.0 2.9 -1.5 0.0 2.8 -2.4 2.7
Hypothyroidism (self reported) 0.2 0.5 1.1 1.1 0.0 -0.8 -1.1 -1.0 -0.3 0.6 0.1
Respiratory disease 2.8 6.1 12.2 -0.4 0.0 3.2 3.5 1.0 2.9 -2.5 3.4
Type 2 Diabetes (T2D) (2018) 0.2 0.4 1.0 0.9 0.0 0.6 0.2 0.6 0.8 -1.0 0.1
Lung FEV1/FVC ratio 0.2 0.9 5.2 -0.2 0.0 0.4 0.5 2.3 0.4 -1.1 -0.1
Lung FVC 0.2 0.9 2.0 0.5 0.0 -0.8 -1.0 -1.4 -1.4 0.8 -0.9
Neuroticism 0.3 0.8 5.4 0.9 0.0 0.2 0.5 2.3 0.1 0.3 0.1
Chronotype (morning person) 1.4 3.3 5.8 2.2 0.0 -2.4 -0.9 -0.8 -2.2 2.4 -2.0
Hair Pigment 0.0 0.6 2.2 -1.0 0.0 0.9 -0.1 0.4 1.0 -0.3 1.5
Tanning 0.3 3.6 8.0 1.0 0.0 -2.8 -1.4 -2.3 -2.0 2.8 -1.2
Hand grip strength (left) 0.8 2.2 4.2 -1.9 0.0 1.2 1.9 1.6 1.5 -0.7 2.0
Number of treatments/medications taken 0.7 1.3 3.1 0.1 0.0 1.8 0.3 0.5 1.7 -1.6 1.2
Average weekly spirits intake 0.1 0.1 0.2 0.2 0.0 0.4 0.3 0.2 0.5 -0.2 0.1
Sensitivity / hurt feelings 0.8 1.4 3.7 0.1 0.0 -1.2 1.6 0.7 -1.4 1.0 -1.9
Frequency of depressed mood in last 2 weeks 0.7 0.9 3.8 0.9 0.0 -0.3 -1.9 1.0 -0.8 1.0 0.5
Hearing difficulty/problems: Yes 0.4 0.5 2.0 1.4 0.0 -0.8 -0.2 -0.1 -0.5 1.2 -0.0
Relative age of first facial hair 0.5 1.1 5.6 -2.4 0.0 -0.3 1.4 -0.6 -0.7 0.4 -0.5
Other serious medical condition/disability diagnosed by doctor 0.0 0.0 0.1 -0.3 0.0 -0.2 -0.2 -0.2 0.1 0.2 -0.1
Ever used hormone-replacement therapy (HRT) 0.5 0.7 1.4 0.5 0.0 0.9 1.2 0.5 1.2 -0.8 0.8
Ever had hysterectomy (womb removed) 0.2 0.2 1.0 0.4 0.0 0.1 -0.0 -1.0 0.4 -0.1 -0.3
Systolic blood pressure, automated reading 0.6 1.8 4.4 0.5 0.0 1.7 0.8 -0.2 2.1 -1.4 2.0
Eye problems/disorders: Diabetes related eye disease 0.9 1.0 3.8 1.4 0.0 0.5 -1.9 0.1 1.0 -0.3 0.7
Angina 0.7 0.9 4.3 0.8 0.0 0.8 -0.0 0.2 1.3 -0.1 2.1
Medication for hormone replacement therapy 1.0 1.1 3.3 -0.2 0.0 1.6 -1.1 -0.6 1.0 -1.8 0.3
Vitamin and mineral supplements 0.9 1.3 4.2 0.9 0.0 0.7 -2.0 -2.0 0.4 -0.3 0.8
Supplements: Zinc 1.0 1.1 4.2 1.3 0.0 0.5 2.1 0.9 0.4 -1.0 -0.5
Medication: Co-codamol 2.2 2.5 7.3 0.1 0.0 2.7 0.6 1.0 1.7 -2.3 1.8
Medication: Metformin 0.4 0.6 2.5 0.7 0.0 -0.7 0.5 1.6 -0.5 0.7 -0.3
Diabetes (father) 0.5 0.6 1.5 -1.0 0.0 -1.0 0.2 0.2 -0.8 1.2 -0.9
Diabetes (mother) 0.3 0.4 2.5 1.6 0.0 0.1 -0.8 -0.3 0.0 -0.3 0.0
Severe depression (siblings) 0.4 0.4 1.1 -0.9 0.0 -0.3 -1.0 -0.7 0.6 0.5 0.5
Pack years adult smoking proportion 1.5 2.3 5.2 0.1 0.0 2.3 -1.1 0.7 1.9 -2.2 1.7
Impedance of leg (right) 0.1 0.7 1.9 0.4 0.0 -0.7 -1.3 -0.1 -1.0 -0.1 -1.4
Leg fat-free mass (left) 0.1 0.7 2.8 -0.2 0.0 -0.8 0.2 0.4 -0.0 1.7 1.3
Trunk fat percentage 0.4 1.6 4.0 0.6 0.0 -2.0 -0.7 -0.7 -1.6 1.8 -1.2
Hand grip strength (right) 0.8 2.1 4.4 -0.7 0.0 1.4 1.5 2.0 1.7 -0.8 2.1
Townsend deprivation index at recruitment 2.0 2.8 8.1 1.7 0.0 2.6 0.0 0.5 1.8 -2.9 1.1
Current tobacco smoking 0.5 0.8 1.8 1.4 0.0 0.8 -1.3 -0.6 0.9 -0.8 0.9
Average weekly fortified wine intake 3.1 3.6 7.5 0.2 0.0 -2.7 -1.9 -0.9 -2.5 2.5 -2.1
Maternal smoking around birth 0.7 1.0 4.1 0.3 0.0 -0.1 1.4 2.0 0.8 0.2 0.9
Fed-up feelings 0.6 1.0 2.4 0.7 0.0 -0.9 -1.2 1.3 -1.5 1.2 -0.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.8 2.2 1.5 0.0 -0.6 -0.8 0.8 -1.2 1.2 -0.0
Relative age voice broke 0.5 0.8 1.8 -0.8 0.0 -0.9 1.3 0.2 -0.9 0.7 -1.3
Taking other prescription medications 0.4 0.6 2.7 1.6 0.0 0.1 0.2 1.3 0.6 -0.4 -0.0
Age when periods started (menarche) 1.3 3.2 6.3 -1.2 0.0 2.3 -2.5 -2.0 1.4 -2.5 0.8
Bilateral oophorectomy (both ovaries removed) 0.2 0.3 0.9 -0.9 0.0 -0.4 -0.1 -0.3 0.1 -0.3 -1.0
Heel bone mineral density (BMD) T-score, automated (left) 0.8 1.7 3.9 -1.6 0.0 -1.6 1.6 0.1 -1.4 2.0 -0.2
Tinnitus: Yes, but not now, but have in the past 2.0 2.1 5.3 0.8 0.0 1.4 -2.3 -1.3 2.0 -1.3 1.3
Qualifications: CSEs or equivalent 0.8 1.1 2.8 0.3 0.0 1.7 -0.7 1.3 0.9 -1.6 0.2
Serious illness, injury or assault to yourself 0.5 0.6 2.5 0.9 0.0 -0.4 1.0 1.6 -0.4 0.5 0.4
High blood pressure 0.2 0.6 1.6 -0.9 0.0 0.9 -0.1 -0.3 1.3 -0.4 1.2
Hayfever, allergic rhinitis or eczema 0.7 1.5 6.5 0.7 0.0 -0.3 -2.5 -1.7 -0.5 -0.9 -1.1
Multivitamins +/- minerals 0.9 1.2 3.6 -1.1 0.0 0.4 1.9 1.8 0.2 -0.9 -0.4
Stomach or abdominal pain in last month 0.3 0.3 1.8 0.0 0.0 0.3 0.4 1.3 -0.2 0.4 0.8
Supplements: Glucosamine 0.7 0.9 1.7 -0.8 0.0 -1.2 1.0 0.6 -1.3 1.1 -0.8
Diverticular disease/diverticulitis (self-reported) 2.1 2.4 5.8 -1.1 0.0 -2.3 -0.4 -1.6 -1.4 1.7 -2.4
Medication: Atenolol 0.3 0.4 1.2 -0.3 0.0 -0.5 0.1 0.3 0.2 1.1 1.1
Medication: Levothyroxine sodium 0.1 0.1 0.5 -0.7 0.0 -0.3 -0.5 -0.3 -0.2 -0.1 0.0
Sitting height 0.3 2.4 6.2 -0.5 0.0 -1.0 1.5 2.5 -0.1 2.2 2.1
Chronic bronchitis/emphysema (father) 0.4 0.5 3.1 1.7 0.0 0.2 -0.2 -0.7 -0.1 -0.3 0.0
High blood pressure (mother) 1.3 1.9 4.4 0.1 0.0 1.9 -1.3 -0.5 2.1 -1.2 2.0
Body mass index (BMI) 0.1 0.4 1.5 -0.1 0.0 0.8 -0.0 -0.3 1.0 -0.4 1.2
Impedance of leg (left) 0.2 1.0 3.5 1.0 0.0 -1.0 -1.2 0.0 -1.2 -0.0 -1.9
Leg predicted mass (left) 0.1 0.6 2.5 -0.2 0.0 -0.7 0.1 0.4 -0.1 1.6 1.3
Trunk fat mass 0.2 0.7 2.5 0.5 0.0 -1.5 -0.4 -0.3 -0.9 1.6 -0.1
Waist circumference 0.1 0.2 0.6 -0.0 0.0 -0.4 -0.8 -0.4 -0.2 0.7 0.5
Number of incorrect matches in round 0.4 0.6 1.6 1.1 0.0 0.6 1.2 1.2 0.4 -0.3 0.4
Past tobacco smoking 1.4 2.5 8.2 -1.4 0.0 -1.5 -1.8 -2.9 -1.1 1.2 -1.4
Alcohol usually taken with meals 1.0 1.6 4.3 -0.4 0.0 -2.1 0.5 -1.4 -1.0 1.4 -1.8
Nervous feelings 0.8 1.5 4.1 2.0 0.0 -0.9 -0.1 1.0 -1.5 0.7 -1.7
Frequency of tenseness / restlessness in last 2 weeks 0.9 1.5 7.5 0.2 0.0 1.4 -2.7 0.7 0.6 -1.0 0.8
Hearing difficulty/problems with background noise 0.8 1.3 5.2 2.3 0.0 -0.7 -0.1 1.6 -0.7 1.0 -0.7
Hair/balding pattern: Pattern 2 0.4 0.5 1.4 0.8 0.0 -0.6 0.3 -0.8 -0.7 1.2 -0.6
Had menopause 0.7 0.9 2.4 0.9 0.0 -1.5 0.9 -0.4 -0.7 1.5 -0.6
Had other major operations 1.1 1.4 3.4 1.4 0.0 0.8 -1.7 -1.8 1.1 -1.0 0.3
Forced vital capacity (FVC) 0.4 1.4 3.4 -0.9 0.0 -1.5 -1.3 -0.2 -1.8 1.8 -0.0
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.7 2.9 -1.7 0.0 -0.5 1.3 -0.1 -0.2 0.6 0.7
Ever unenthusiastic/disinterested for a whole week 0.4 0.4 1.4 -0.3 0.0 -0.5 -0.7 1.2 -0.9 0.4 -0.4
Qualifications: None of the above 0.4 0.8 3.2 1.8 0.0 -0.7 -0.7 0.2 -0.7 0.4 -1.2
Financial difficulties in last 2 years 0.5 0.6 2.2 0.3 0.0 0.4 0.6 1.1 1.0 -0.1 1.5
Mouth/teeth dental problems 0.7 1.1 2.3 -0.6 0.0 -1.3 1.5 -1.5 -0.6 1.1 -0.6
Heart attack 1.8 2.3 5.0 -2.2 0.0 1.7 1.0 0.8 1.7 -1.2 2.2
Allergy 0.3 0.7 2.9 -0.8 0.0 -0.6 0.9 0.6 -0.6 1.7 -0.0
Pain all over the body in last month 0.2 0.2 1.2 -0.2 0.0 -0.2 -0.2 1.1 -0.3 0.1 -0.4
Diabetes (self-reported) 0.3 0.4 1.6 0.9 0.0 0.1 -0.1 1.3 0.7 -0.3 0.3
Hayfever/allergic rhinitis (self-reported) 1.1 1.4 3.1 0.9 0.0 -1.1 -1.5 -1.5 -1.1 0.7 -1.7
Medication: Ramipril 0.3 0.3 1.3 -1.1 0.0 0.1 1.0 -0.2 0.4 -0.2 0.4
Medication: Simvastatin 4.0 5.8 15.2 -0.4 0.0 3.1 1.2 1.6 3.5 -2.3 3.9
Fluid intelligence score 0.2 0.5 1.0 1.0 0.0 0.4 0.8 0.8 0.8 -0.7 0.6
Illnesses of siblings 0.3 0.4 2.0 -1.4 0.0 0.0 0.0 0.4 -0.7 -0.4 -0.8
Neuroticism score 0.6 1.2 4.2 1.2 0.0 -0.8 -0.1 2.1 -1.1 1.2 -0.8
Weight 0.1 0.4 2.0 -0.1 0.0 -0.3 0.3 0.3 0.3 1.0 1.4
Impedance of arm (right) 1.2 5.6 14.5 0.3 0.0 -3.8 -0.4 -0.0 -3.3 2.9 -3.3
Arm fat percentage (right) 0.2 0.7 1.5 0.3 0.0 -1.2 -0.8 -0.7 -1.0 1.1 -0.8
Trunk fat-free mass 0.2 1.4 7.7 -0.1 0.0 0.8 0.7 0.7 1.4 0.5 2.8
Hip circumference 0.5 2.1 6.0 -0.1 0.0 -2.3 -0.6 -0.7 -1.9 2.4 -1.1
Time employed in main current job 0.3 0.3 0.8 -0.8 0.0 -0.3 0.5 0.9 0.9 0.1 0.3
Alcohol intake versus 10 years previously 0.4 0.6 3.1 1.8 0.0 -0.2 0.0 1.3 0.3 0.4 0.0
Father’s age at death 0.4 0.6 2.0 0.6 0.0 0.2 1.1 1.4 0.7 -0.7 0.2
Worrier / anxious feelings 0.2 0.5 1.7 -1.1 0.0 -0.5 0.3 1.3 -0.3 0.5 -0.5
Frequency of tiredness / lethargy in last 2 weeks 0.8 1.3 2.1 -0.1 0.0 -1.3 -1.3 1.4 -1.5 1.4 -1.1
Falls in the last year 1.5 2.0 3.5 1.2 0.0 -1.9 -1.8 -1.4 -1.2 1.7 -1.4
Hair/balding pattern: Pattern 3 0.1 0.2 0.8 0.9 0.0 0.4 0.3 0.1 0.2 0.1 0.8
Number of live births 0.3 0.5 1.5 -0.2 0.0 -1.2 -0.8 -0.5 -0.7 0.9 -0.5
Forced expiratory volume in 1-second (FEV1) 0.3 1.1 2.9 -0.4 0.0 -1.4 -1.2 0.5 -1.7 1.4 -0.2
Pulse rate 0.9 1.6 3.6 1.9 0.0 -1.4 -1.6 -0.4 -1.3 1.2 -1.1
Happiness 2.6 3.1 6.3 1.6 0.0 -2.2 -2.5 -0.8 -2.0 1.9 -1.7
Noisy workplace 0.8 1.0 2.9 1.6 0.0 0.1 0.4 1.4 0.6 0.4 1.7
Qualifications: A levels/AS levels or equivalent 0.2 0.4 2.0 0.5 0.0 -0.1 -0.6 0.3 -1.4 -0.2 -0.9
Serious illness, injury or assault of a close relative in last 2 years 2.4 2.8 8.8 1.9 0.0 -1.8 -0.8 0.0 -1.9 1.5 -3.0
Mouth/teeth dental problems: Dentures 0.2 0.4 1.0 -0.3 0.0 1.0 0.5 0.9 0.6 -0.8 0.6
Asthma 0.8 1.6 4.4 0.1 0.0 1.4 2.1 0.5 1.4 -1.4 1.6
Medication: Ibuprofen (e.g. Nurofen) 1.4 1.7 4.9 -0.6 0.0 -1.5 -0.2 0.1 -2.2 1.6 -2.0
Medication: Cholesterol lowering 2.2 3.4 8.8 -1.4 0.0 1.7 1.7 2.1 2.3 -1.0 3.0
Depression (self-reported) 1.7 2.0 6.9 2.4 0.0 -0.6 -0.6 2.6 -0.9 1.3 0.2
Medication: Lansoprazole 0.6 0.7 1.6 -1.0 0.0 -1.0 0.9 1.0 0.4 1.3 0.1
Prospective memory result 0.3 0.4 1.5 0.1 0.0 0.8 -0.6 -0.1 0.7 -1.2 0.2
Lung cancer (father) 0.1 0.1 0.2 0.4 0.0 -0.4 0.2 0.4 -0.3 0.0 -0.1
Illnesses of mother 3.6 4.5 13.1 0.2 0.0 -2.9 -0.2 -1.5 -3.1 1.6 -3.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.3 1.3 -1.1 0.0 -0.1 -0.5 0.5 -0.7 0.1 0.5
Pulse wave Arterial Stiffness index 0.3 0.4 0.8 0.9 0.0 0.2 0.9 0.7 0.9 -0.4 0.3
Impedance of arm (left) 1.6 7.2 17.4 0.2 0.0 -4.2 -0.6 -1.0 -3.8 3.3 -3.7
Arm fat mass (right) 0.1 0.2 0.7 0.1 0.0 -0.6 -0.7 -0.3 -0.3 0.8 0.2
Trunk predicted mass 0.3 1.5 8.0 -0.2 0.0 0.8 0.8 0.8 1.4 0.4 2.8
Standing height 0.3 2.5 10.0 0.3 0.0 -2.5 0.5 1.2 -1.5 3.2 0.6
Length of working week for main job 1.4 1.6 5.6 0.6 0.0 1.7 -0.5 0.2 1.8 -2.4 0.6
Exposure to tobacco smoke at home 0.3 0.3 1.0 -0.7 0.0 -0.5 0.2 0.5 -0.8 1.0 -0.0
Breastfed as a baby 0.5 0.6 2.2 0.2 0.0 -0.7 -0.6 -0.6 -1.1 0.6 -1.5
Tense / ‘highly strung’ 0.3 0.6 1.5 0.8 0.0 -0.1 -1.0 1.2 -1.1 0.5 -0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.9 1.3 5.5 2.0 0.0 0.2 -0.5 2.4 0.7 0.2 0.6
Hair/balding pattern: Pattern 4 0.2 0.5 0.9 0.7 0.0 -0.9 -0.5 0.6 -0.7 0.9 -0.5
Birth weight of first child 0.5 0.9 2.6 1.5 0.0 -0.8 -1.6 0.1 -0.9 0.3 -1.1
Peak expiratory flow (PEF) 0.2 0.4 1.3 -0.2 0.0 -0.6 -1.1 0.4 -1.1 0.3 -0.3
Pulse wave reflection index 0.4 0.4 0.9 0.4 0.0 0.9 0.0 0.4 0.9 -0.9 0.8
Ever highly irritable/argumentative for 2 days 1.1 1.3 7.7 2.8 0.0 0.3 -1.0 0.7 0.5 -0.8 0.4
Loud music exposure frequency 0.9 1.0 3.5 1.4 0.0 1.0 -0.3 0.8 0.7 -0.4 1.9
Qualifications: O levels/GCSEs or equivalent 0.3 0.4 1.1 -0.4 0.0 0.4 0.6 1.1 0.7 -0.3 1.0
Mouth/teeth dental problems: Bleeding gums 1.1 1.4 6.0 1.6 0.0 -0.6 -2.5 0.4 -1.2 0.7 -0.3
Blood clot in the leg (DVT) 0.4 0.5 1.3 -0.5 0.0 1.1 0.5 0.3 1.1 -1.0 0.3
Medication: Paracetamol 0.2 0.3 0.8 0.1 0.0 -0.5 0.1 0.9 -0.7 0.2 -0.7
Headache pain in last month 0.3 0.6 1.3 0.4 0.0 1.1 -0.1 0.5 1.0 -1.1 0.8
Medication for cholesterol, blood pressure or diabetes 1.0 1.7 7.0 -0.1 0.0 -1.1 -0.7 -0.8 -2.1 0.4 -2.6
Glaucoma (self-reported) 0.8 0.9 5.3 0.4 0.0 0.6 2.3 1.1 0.4 -0.4 0.3
Gout (self-reported) 1.2 1.6 5.1 -0.9 0.0 1.4 1.4 0.7 1.7 -2.3 0.1
Hypothyroidism/myxoedema (self-reported) 0.3 0.7 2.1 0.2 0.0 -1.0 -1.0 -1.4 -0.5 0.8 -0.5
Medication: Amlodipine 0.4 0.6 1.4 0.4 0.0 -1.0 -0.5 -0.0 -1.1 1.2 -0.7
Medication: Ventolin 100micrograms inhaler 0.2 0.3 1.0 -1.0 0.0 0.2 0.9 -0.3 0.3 0.1 0.4
Birth weight 0.2 0.5 1.8 0.7 0.0 0.5 -0.9 0.3 0.6 -0.4 1.3
Chronic bronchitis/emphysema (mother) 2.7 3.1 11.2 -1.6 0.0 1.1 3.4 1.8 1.9 -0.8 1.6
High blood pressure (siblings) 0.3 0.4 1.9 0.8 0.0 0.5 0.2 -0.1 0.8 0.2 1.4
Forced vital capacity (FVC), Best measure 0.1 0.5 1.7 -1.3 0.0 -0.5 -0.4 -0.1 -1.0 0.8 0.3
Body fat percentage 0.2 0.9 2.2 0.7 0.0 -1.5 -0.7 -0.8 -1.2 1.3 -0.8
Leg fat percentage (right) 0.1 0.5 1.0 0.7 0.0 0.9 -0.5 -0.4 0.8 -0.8 1.0
Arm fat-free mass (right) 0.2 1.0 5.1 -0.0 0.0 0.8 0.3 0.6 1.2 0.1 2.2
Exposure to tobacco smoke outside home 0.3 0.4 1.4 -0.6 0.0 1.2 0.1 0.3 0.8 -0.8 0.5
Comparative body size at age 10 0.2 0.6 1.9 -0.6 0.0 1.2 0.1 0.2 1.1 -1.4 0.1
Number of full brothers 1.3 1.6 3.2 1.3 0.0 -1.8 -1.0 -0.9 -1.0 1.7 -1.5
Worry too long after embarrassment 1.1 1.9 4.0 -0.4 0.0 -1.5 2.0 1.3 -1.2 1.9 -1.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.6 0.8 2.0 0.6 0.0 -1.0 0.2 0.6 -1.4 1.4 -0.7
Wheeze or whistling in the chest in last year 0.4 0.7 1.7 1.3 0.0 0.7 0.8 0.8 1.2 -0.7 0.6
Number of children fathered 0.4 0.5 1.2 -0.9 0.0 -1.0 -0.3 0.3 -0.4 1.1 0.4
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.3 0.9 0.3 0.0 -0.7 0.6 -0.0 -0.8 0.3 -1.0
Age at first live birth 0.8 1.4 4.8 -0.1 0.0 -1.3 0.6 2.2 -1.4 1.2 -1.1
Pulse wave peak to peak time 0.7 0.8 1.8 -1.1 0.0 -0.7 -0.9 -0.8 -1.3 0.9 -0.5
Health satisfaction 1.1 1.5 3.6 0.9 0.0 -1.5 1.1 1.9 -1.0 1.5 -0.7
Shortness of breath walking on level ground 1.2 1.5 5.1 2.0 0.0 -0.4 1.1 2.3 -0.2 1.0 0.5
Qualifications: College or University degree 0.9 3.0 5.3 -0.3 0.0 -2.1 -1.4 -2.3 -2.0 1.7 -2.3
Eye problems/disorders: None of the above 0.2 0.3 0.7 -0.5 0.0 -0.3 0.8 0.5 -0.8 0.1 -0.5
Mouth/teeth dental problems: Loose teeth 1.1 1.3 2.7 0.2 0.0 1.3 1.1 1.2 1.6 -1.4 1.2
Emphysema/chronic bronchitis 3.7 4.1 13.8 1.4 0.0 2.9 0.3 2.0 1.9 -3.7 0.9
Medication for pain relief, constipation, heartburn 0.2 0.4 2.0 -0.5 0.0 -0.7 -0.1 -1.4 -0.3 0.6 -0.3
Neck or shoulder pain in last month 1.0 1.4 3.7 1.2 0.0 -1.0 -1.9 -1.7 -0.7 1.2 -0.7
Medication: Blood pressure 0.3 0.5 1.8 0.7 0.0 0.6 -0.5 0.1 1.3 0.0 1.2
Angina (self-reported) 0.4 0.5 2.9 0.6 0.0 0.4 -0.2 0.1 0.8 0.3 1.7
Migraine (self-reported) 0.2 0.3 1.3 -0.3 0.0 0.5 -1.1 -0.7 0.1 -0.0 0.3
Medication: Ibuprofen 1.7 2.1 6.7 -0.2 0.0 -1.6 -0.6 0.2 -2.6 1.8 -1.9
Medication: Allopurinol 2.2 2.9 7.7 -0.7 0.0 1.8 1.8 2.3 1.8 -2.8 0.7
Medication: Omeprazole 2.4 2.9 15.9 2.4 0.0 -0.0 -4.0 -0.4 0.0 -0.6 -0.9
Medication: Seretide 50 evohaler 0.6 0.7 2.4 -0.9 0.0 0.9 1.6 0.2 0.8 -0.8 0.6
Mean time to correctly identify matches 0.3 0.6 3.0 0.4 0.0 0.3 1.7 0.2 0.3 -1.0 0.1
Heart disease (mother) 2.2 2.7 8.2 -0.9 0.0 2.1 -1.2 1.0 2.2 -1.1 2.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.3 1.6 3.1 1.0 0.0 1.4 -0.6 1.2 1.4 -1.7 1.6
Whole body fat mass 0.1 0.4 1.3 0.4 0.0 -1.0 -0.5 -0.4 -0.6 1.1 0.0
Leg fat mass (right) 0.1 0.3 1.4 0.3 0.0 0.5 -0.7 0.1 0.7 -0.2 1.2
Arm predicted mass (right) 0.2 1.0 5.1 -0.0 0.0 0.8 0.7 0.7 1.1 0.2 2.3
Pulse rate, automated reading 0.2 0.7 3.0 1.7 0.0 -0.8 -0.7 -0.0 -0.3 1.1 0.0
Alcohol intake frequency. 1.2 2.7 6.1 0.8 0.0 2.0 1.3 2.5 1.9 -1.9 1.3
Comparative height size at age 10 0.4 2.3 8.2 -0.2 0.0 -2.5 1.0 0.2 -1.8 2.9 -0.2
Number of full sisters 0.9 1.2 4.8 -0.5 0.0 -1.0 2.2 -0.3 -0.7 1.0 -1.3
Suffer from ‘nerves’ 1.1 1.7 7.8 0.1 0.0 0.0 1.8 2.8 0.8 0.7 1.1
Overall health rating 0.2 0.5 2.4 1.1 0.0 0.2 -1.6 0.3 0.1 0.4 0.6
Chest pain or discomfort 0.8 1.1 2.8 0.6 0.0 0.9 -1.1 1.7 1.4 -0.2 1.3
Had major operations 2.0 2.3 4.9 1.6 0.0 -2.2 -0.9 -0.1 -2.0 2.1 -1.3
Age at last live birth 2.2 3.2 6.5 1.2 0.0 -2.5 -0.4 1.4 -2.3 2.2 -2.3
Family relationship satisfaction 0.3 0.4 1.4 -1.2 0.0 -0.1 0.1 0.6 -1.0 0.1 -0.8
Leg pain on walking 1.2 1.5 5.1 2.2 0.0 -1.1 -1.6 -0.6 -0.8 1.1 -0.6
Qualifications: NVQ or HND or HNC or equivalent 1.4 1.6 3.4 0.1 0.0 1.8 -0.1 1.2 1.7 -1.7 1.6
Commuting to job workplace: Car/motor vehicle 0.4 0.5 3.0 -0.1 0.0 0.7 -0.6 -0.2 0.3 -0.1 1.7
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 2.2 -0.8 0.0 0.6 0.1 -1.5 0.8 -0.2 1.0
Medication: Aspirin 3.0 4.0 9.1 0.4 0.0 2.7 0.2 1.6 3.0 -2.4 2.7
Supplements: Vitamin C 0.8 0.9 2.3 0.7 0.0 -1.2 0.4 0.1 -1.4 1.1 -1.5
Knee pain experienced in last month 0.8 1.2 3.4 -0.9 0.0 -1.2 -0.9 -1.9 -0.6 1.4 -0.7
Hypertension (Self-reported) 0.3 0.8 1.9 -1.0 0.0 1.0 0.1 -0.0 1.4 -0.6 1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.3 2.3 1.5 0.0 0.2 0.3 0.4 0.0 -0.1 0.4
Illnesses of father: Heart disease 0.6 0.8 4.0 -1.0 0.0 0.4 -0.3 0.1 0.9 0.3 2.0
Illnesses of siblings: Diabetes 0.5 0.6 2.1 0.5 0.0 -1.0 1.0 0.1 -0.4 1.4 -0.1
Smoking status: Previous 1.5 2.2 8.0 1.0 0.0 0.7 2.7 2.8 0.3 -0.5 0.3
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.5 1.7 0.4 0.0 -0.7 -0.6 0.0 -1.3 0.7 -0.9
Whole body fat-free mass 0.2 0.9 4.9 -0.1 0.0 0.2 0.6 0.7 0.9 0.9 2.2
Leg fat-free mass (right) 0.1 0.6 2.2 0.0 0.0 -0.7 0.3 0.6 0.1 1.5 1.3
Arm fat percentage (left) 0.3 1.0 1.8 0.3 0.0 -1.4 -0.9 -1.2 -1.2 1.3 -1.0
Average weekly red wine intake 0.6 0.9 2.1 1.2 0.0 -0.7 -1.5 0.4 -1.1 0.9 -0.9
Handedness (chirality/laterality): Left-handed 0.3 0.3 1.0 0.1 0.0 -1.0 -1.0 0.4 -0.1 0.5 -0.6
Mood swings 0.5 0.9 3.9 0.2 0.0 -0.8 -0.2 2.0 -0.9 1.2 -0.3
Loneliness, isolation 1.0 1.4 4.8 0.6 0.0 -1.6 0.0 1.0 -1.5 2.2 -0.6
Long-standing illness, disability or infirmity 0.1 0.2 0.6 0.6 0.0 0.3 -0.5 0.8 0.4 -0.2 0.4
Ever had bowel cancer screening 0.5 0.6 2.4 -1.3 0.0 0.2 1.6 0.3 0.5 -0.5 0.5
Diabetes diagnosed by doctor 0.2 0.3 1.0 0.7 0.0 0.3 0.2 1.0 0.5 -0.5 0.3
Ever had stillbirth, spontaneous miscarriage or termination 1.1 1.2 3.0 0.4 0.0 1.7 -1.0 -0.8 1.1 -1.4 1.2
Friendships satisfaction 0.4 0.5 3.1 -0.3 0.0 -0.2 -0.5 1.8 -0.8 -0.1 -0.1
Qualifications: nursing, teaching 0.2 0.3 2.1 0.3 0.0 -0.2 0.1 0.3 0.6 0.2 1.4
Commuting to job workplace: Walk 0.5 0.6 1.8 1.3 0.0 0.2 -0.2 0.7 -0.3 -0.7 -1.3
Eye problems/disorders: Cataract 0.1 0.2 0.7 -0.8 0.0 0.2 0.2 0.5 -0.1 0.2 0.4
Mouth/teeth dental problems: Mouth ulcers 0.5 0.7 3.3 1.8 0.0 0.4 -0.7 1.0 -0.9 -0.1 -0.1
Medication for cholesterol 3.6 5.4 12.0 2.1 0.0 -3.5 -0.1 0.5 -3.2 3.4 -2.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.8 1.0 2.3 -0.5 0.0 -1.5 -1.0 -0.5 -1.2 1.1 -1.0
Back pain experienced in last month 0.4 0.5 1.4 0.5 0.0 -0.9 -0.8 -0.2 -0.9 1.2 -0.1
Mineral and other dietary supplements 0.4 0.6 2.0 -0.0 0.0 -0.1 -1.4 -1.2 -0.5 -0.1 -0.9
Breast cancer (self-reported) 0.5 0.6 2.0 1.4 0.0 -0.0 -0.4 1.4 0.5 -0.0 -0.3
Asthma (self-reported) 0.6 1.1 3.6 0.2 0.0 1.1 1.9 0.3 1.1 -0.9 1.5
Osteoporosis (self-reported) 1.3 1.6 4.8 -2.2 0.0 1.3 0.9 1.0 1.1 -1.1 1.3
Osteoarthritis (self-reported) 1.4 1.9 7.1 -0.7 0.0 -1.4 -1.0 -2.7 -1.4 1.5 -0.6
Medication: Aspirin 3.1 4.1 9.0 0.5 0.0 2.7 0.2 1.9 3.0 -2.5 2.6
Medication: Gliclazide 1.2 1.3 2.8 -0.8 0.0 -1.7 -1.1 -1.0 -1.3 1.0 -1.4
Illnesses of father: None of the above (group 1) 1.5 1.8 3.7 -1.3 0.0 -1.8 0.7 -0.4 -1.9 1.1 -1.9
Smoking status: Current 0.4 0.6 1.7 1.0 0.0 0.7 -1.3 -0.6 0.7 -0.7 0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.2 0.4 0.5 0.0 0.6 0.5 0.5 -0.5 -0.5 0.6
Whole body water mass 0.1 0.8 4.5 -0.0 0.0 0.2 0.5 0.7 0.8 0.9 2.1
Leg predicted mass (right) 0.1 0.6 2.3 0.0 0.0 -0.7 0.4 0.6 0.0 1.5 1.2
Arm fat mass (left) 0.0 0.2 0.7 -0.0 0.0 -0.6 -0.3 -0.2 -0.4 0.8 0.2
Number of self-reported non-cancer illnesses 1.2 2.0 5.8 0.7 0.0 1.9 -0.1 -0.0 2.4 -1.7 1.8
Average weekly champagne plus white wine intake 0.2 0.3 0.6 -0.8 0.0 0.4 0.5 -0.8 0.6 -0.7 0.1
Miserableness 0.5 0.9 3.5 0.6 0.0 -0.9 -0.1 1.2 -0.9 1.9 0.6
Guilty feelings 0.8 1.2 4.5 1.1 0.0 -0.8 0.7 2.1 -0.9 1.4 -0.3
Wears glasses or contact lenses 0.2 0.2 0.7 -0.4 0.0 -0.0 -0.6 -0.8 0.4 0.3 0.6
Ever taken oral contraceptive pill 0.4 0.4 2.2 0.1 0.0 -0.0 -1.5 -0.7 -0.2 0.3 0.6
Hearing aid user 1.2 1.4 4.7 2.0 0.0 -0.7 -2.2 -0.5 -0.7 0.9 -0.6
Mother’s age at death 1.6 2.0 7.0 1.9 0.0 -1.1 -1.5 -0.8 -1.3 0.1 -2.7
Financial situation satisfaction 1.0 1.2 6.2 2.5 0.0 -0.3 -1.1 1.0 -0.2 1.0 0.4
Tinnitus: Yes, now most or all of the time 0.7 0.8 3.7 1.6 0.0 0.4 -1.9 -0.5 -0.0 -0.3 0.2
Commuting to job workplace: Public transport 0.8 1.0 3.6 -1.3 0.0 -0.6 1.9 1.1 -0.5 0.6 -0.6
Eye problems/disorders: Glaucoma 0.7 0.8 5.2 0.5 0.0 0.2 2.3 1.0 0.3 -0.0 -0.2
Medication: Blood pressure 1.2 2.3 5.1 -1.8 0.0 1.7 0.9 -0.9 2.2 -1.6 1.7
Pain type(s) experienced in last month: Hip pain 2.0 2.6 6.0 -0.3 0.0 -2.5 -1.2 -1.5 -1.9 2.4 -1.3
Supplements: Fish oil (including cod liver oil) 0.1 0.2 0.8 0.4 0.0 -0.0 0.9 0.4 0.3 0.2 0.2
High cholesterol (Self-reported) 1.8 3.1 6.4 -2.5 0.0 2.0 1.8 0.9 1.9 -1.7 2.0
Medication: Bendroflumethiazide 0.5 0.8 3.4 -0.5 0.0 0.2 -1.4 -1.9 0.7 -0.6 0.1
Medication: Paracetamol 0.2 0.2 1.1 -0.6 0.0 0.0 0.1 1.0 -0.4 -0.3 -0.4
Medication: Lisinopril 1.0 1.3 3.3 0.7 0.0 1.5 0.2 -0.8 1.7 -1.8 0.6
Medication: Atorvastatin 0.3 0.4 0.9 -0.8 0.0 -0.5 -0.9 -0.9 -0.4 0.2 -0.5
Illnesses of father: High blood pressure 0.9 1.1 2.4 0.6 0.0 1.5 -0.9 -1.1 1.5 -0.4 1.6
Alcohol drinker status: Never 0.4 0.4 2.2 0.9 0.0 0.4 0.5 1.5 -0.1 -0.4 -0.0
Ever smoked 1.1 1.9 3.5 1.8 0.0 1.5 0.8 1.9 1.2 -0.9 1.7
Basal metabolic rate 0.1 0.7 4.1 -0.0 0.0 0.1 0.4 0.6 0.8 0.9 2.0
Leg fat percentage (left) 0.1 0.4 1.1 1.0 0.0 0.6 -0.4 -0.5 0.6 -0.6 0.6
Arm fat-free mass (left) 0.2 1.1 4.8 -0.1 0.0 0.8 0.8 1.2 1.3 0.1 2.2
Number of operations (self-reported) 0.9 1.3 5.2 1.6 0.0 -0.7 -2.3 -0.9 -0.5 0.8 -0.5
Average weekly beer plus cider intake 0.2 0.4 1.1 0.3 0.0 0.6 1.1 -0.2 0.7 -0.4 0.7
Irritability 0.6 1.1 5.8 2.4 0.0 0.2 -0.7 1.2 -0.6 -0.4 0.4
Risk taking 0.3 0.4 1.7 1.3 0.0 0.4 -0.7 0.2 0.3 -0.7 0.0
Ever had prostate specific antigen (PSA) test 0.8 0.9 2.3 -0.7 0.0 -1.2 -1.5 -0.7 -0.6 0.7 -1.3
Fractured/broken bones in last 5 years 0.1 0.1 0.5 -0.4 0.0 0.1 -0.3 -0.2 0.0 -0.4 -0.7
Age started oral contraceptive pill 0.7 0.8 3.3 1.1 0.0 0.2 1.0 1.8 0.5 -0.6 0.7
Diastolic blood pressure, automated reading 0.2 0.6 2.1 -0.0 0.0 -0.7 -0.8 -1.5 -0.2 1.1 -0.1
Ever depressed for a whole week 0.4 0.5 1.0 0.3 0.0 0.9 -1.0 0.8 0.5 -0.9 0.2
Unable to work because of sickness or disability 0.5 0.6 1.7 -1.3 0.0 0.5 -1.1 -1.1 -0.2 -0.7 0.3
Commuting to job workplace: Cycle 0.3 0.3 1.8 -0.3 0.0 -0.4 -0.2 -1.3 -0.3 0.0 -0.7
Myopia 0.5 0.7 2.3 -0.3 0.0 -1.5 -0.4 0.2 -0.9 1.5 -0.4
Vascular/heart problems diagnosed by doctor 0.4 1.2 3.4 1.0 0.0 -1.3 0.1 0.2 -1.7 0.7 -1.8
Cholesterol lowering medication 2.7 4.0 9.5 -1.0 0.0 2.9 0.1 0.8 3.1 -2.6 2.5
Medication: Omeprazole (e.g. Zanprol) 1.5 1.9 8.8 2.0 0.0 0.5 -3.0 0.1 0.7 -1.0 -0.3
Pain experienced in last month 0.3 0.4 1.7 0.4 0.0 -0.0 1.3 1.0 -0.8 0.2 -0.0
Supplements: Calcium 0.5 0.5 1.3 -1.0 0.0 0.4 1.1 1.2 0.1 -0.5 0.0
Basal cell carcinoma (self-reported) 0.9 1.1 4.1 0.3 0.0 1.7 -0.5 -0.9 0.8 -2.0 0.0
Heart attack/myocardial infarction (self-reported) 2.0 2.5 5.7 -2.4 0.0 2.0 0.8 0.6 1.6 -1.6 2.1
Deep venous thrombosis (DVT) (self-reported) 0.7 0.8 2.0 -0.6 0.0 1.4 0.8 0.6 1.3 -1.2 0.6
Heart disease (siblings) 1.7 2.1 5.1 0.9 0.0 1.6 -1.9 -0.4 2.3 -1.5 1.7
Alcohol drinker status: Previous 0.5 0.6 1.9 -0.4 0.0 0.9 0.2 0.6 1.0 -1.4 0.4
Pack years of smoking 1.7 2.5 5.7 -0.1 0.0 2.3 -0.7 0.7 2.1 -2.4 1.8
Impedance of whole body 0.8 3.9 10.2 0.6 0.0 -3.0 -0.8 -0.5 -2.8 1.8 -3.2
Leg fat mass (left) 0.0 0.2 0.8 0.3 0.0 0.2 -0.5 -0.0 0.4 -0.1 0.9
Arm predicted mass (left) 0.3 1.3 5.2 -0.2 0.0 0.8 1.0 1.2 1.5 -0.0 2.3