Best TWAS P=2.13e-08 · Best GWAS P=1.5e-07 conditioned to 0.0173
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Esophageal Carcinoma | KIAA1109 | 0.32 | 0.02 | blup | 45 | 0.02 | 7.4e-02 | 5.0 | -5.6 | 2.1e-08 | -0.60 | 0 | 0.81 | TRUE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | KIAA1109 | 0.06 | 0.05 | lasso | 2 | 0.03 | 7.1e-05 | 5.1 | -5.2 | 1.8e-07 | -0.75 | 0 | 1.00 | FALSE |