[Hub]/) : Traits : Ulcerative Colitis (UC) : ← →

chr5:12,225-1,390,349

Best TWAS P=4.83e-11 · Best GWAS P=3.14e-09 conditioned to 0.169

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Prostate	EXOC3	0.23	0.13	lasso	14	0.06	1.1e-02	-5.3	6.6	4.8e-11	-0.77	0.02	0.90	TRUE
1	GTEx	Artery Tibial	AC026740.1	0.08	0.06	lasso	3	0.05	1.0e-04	-5.5	5.9	3.7e-09	-0.79	0.02	0.96	FALSE
13	METSIM	Adipose	TPPP	0.04	0.00	blup	355	0.01	1.2e-02	-5.9	5.7	1.1e-08	-0.69	0.01	0.98	FALSE
2	GTEx	Brain Frontal Cortex BA9	AC026740.1	0.17	0.02	enet	13	0.06	9.5e-03	2.9	5.6	2.0e-08	-0.66	0.04	0.49	FALSE
5	GTEx	Esophagus Muscularis	AC026740.1	0.12	0.10	lasso	6	0.08	1.1e-05	-5.1	5.6	2.1e-08	-0.72	0.04	0.94	FALSE
12	GTEx	Whole Blood	EXOC3	0.08	0.10	enet	7	0.10	1.2e-09	-4.8	5.6	2.4e-08	-0.47	0.66	0.34	FALSE
4	GTEx	Esophagus Mucosa	AC026740.1	0.17	0.07	lasso	5	0.07	2.2e-05	-5.5	5.5	2.9e-08	-0.75	0.04	0.95	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	AC026740.1	0.15	0.10	lasso	5	0.20	1.9e-11	-5.5	5.5	4.2e-08	-0.71	0.04	0.96	FALSE
11	GTEx	Testis	AC026740.1	0.19	0.04	enet	8	0.06	1.3e-03	-5.5	5.5	4.4e-08	-0.67	0.02	0.96	FALSE
3	GTEx	Colon Sigmoid	AC026740.1	0.13	0.06	lasso	3	0.03	3.8e-02	-5.3	5.5	5.0e-08	-0.75	0.04	0.74	FALSE
10	GTEx	Stomach	AC026740.1	0.13	0.01	lasso	4	0.03	1.5e-02	-5.5	5.4	5.9e-08	-0.71	0.02	0.83	FALSE
6	GTEx	Ovary	CTD-2228K2.7	0.29	0.03	enet	26	0.08	4.8e-03	-5.3	-5.4	6.2e-08	0.75	0.03	0.83	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC9A3	0.04	0.02	blup	63	0.02	9.4e-04	-4.8	-5.4	6.6e-08	0.58	0.07	0.40	FALSE
7	GTEx	Pancreas	EXOC3	0.15	0.09	lasso	4	0.14	2.0e-06	-4.8	5.4	7.8e-08	-0.50	0.11	0.81	FALSE