[Hub]/) : Traits : Ulcerative Colitis (UC) :

chr5:12,225-1,390,349

Best TWAS P=4.83e-11 · Best GWAS P=3.14e-09 conditioned to 0.169

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial AC026740.1 0.08 0.06 lasso 3 0.05 1.0e-04 -5.5 5.9 3.7e-09 -0.79 0.02 0.96 FALSE
2 GTEx Brain Frontal Cortex BA9 AC026740.1 0.17 0.02 enet 13 0.06 9.5e-03 2.9 5.6 2.0e-08 -0.66 0.04 0.49 FALSE
3 GTEx Colon Sigmoid AC026740.1 0.13 0.06 lasso 3 0.03 3.8e-02 -5.3 5.5 5.0e-08 -0.75 0.04 0.74 FALSE
4 GTEx Esophagus Mucosa AC026740.1 0.17 0.07 lasso 5 0.07 2.2e-05 -5.5 5.5 2.9e-08 -0.75 0.04 0.95 FALSE
5 GTEx Esophagus Muscularis AC026740.1 0.12 0.10 lasso 6 0.08 1.1e-05 -5.1 5.6 2.1e-08 -0.72 0.04 0.94 FALSE
6 GTEx Ovary CTD-2228K2.7 0.29 0.03 enet 26 0.08 4.8e-03 -5.3 -5.4 6.2e-08 0.75 0.03 0.83 FALSE
7 GTEx Pancreas EXOC3 0.15 0.09 lasso 4 0.14 2.0e-06 -4.8 5.4 7.8e-08 -0.50 0.11 0.81 FALSE
8 GTEx Prostate EXOC3 0.23 0.13 lasso 14 0.06 1.1e-02 -5.3 6.6 4.8e-11 -0.77 0.02 0.90 TRUE
9 GTEx Skin Not Sun Exposed Suprapubic AC026740.1 0.15 0.10 lasso 5 0.20 1.9e-11 -5.5 5.5 4.2e-08 -0.71 0.04 0.96 FALSE
10 GTEx Stomach AC026740.1 0.13 0.01 lasso 4 0.03 1.5e-02 -5.5 5.4 5.9e-08 -0.71 0.02 0.83 FALSE
11 GTEx Testis AC026740.1 0.19 0.04 enet 8 0.06 1.3e-03 -5.5 5.5 4.4e-08 -0.67 0.02 0.96 FALSE
12 GTEx Whole Blood EXOC3 0.08 0.10 enet 7 0.10 1.2e-09 -4.8 5.6 2.4e-08 -0.47 0.66 0.34 FALSE
13 METSIM Adipose TPPP 0.04 0.00 blup 355 0.01 1.2e-02 -5.9 5.7 1.1e-08 -0.69 0.01 0.98 FALSE
14 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SLC9A3 0.04 0.02 blup 63 0.02 9.4e-04 -4.8 -5.4 6.6e-08 0.58 0.07 0.40 FALSE