Best TWAS P=5.34e-17 · Best GWAS P=1.13e-18 conditioned to 0.0029
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Lung Adenocarcinoma | IL12B | 0.07 | 0.00 | blup | 48 | 0.04 | 8.0e-06 | -5.8 | 8.4 | 5.3e-17 | -0.89 | 0.01 | 0.66 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | IL12B | 0.15 | 0.04 | blup | 48 | 0.08 | 8.9e-10 | -5.8 | 7.0 | 2.0e-12 | -0.51 | 0.02 | 0.98 | FALSE |