Best TWAS P=5.23e-08 · Best GWAS P=3.9e-07 conditioned to 0.87
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | WBSCR26 | 0.12 | 0.15 | lasso | 3 | 0.18 | 1.9e-19 | 5.3 | -5.4 | 5.2e-08 | -0.92 | 0.00 | 1.00 | TRUE |
| 6 | The Cancer Genome Atlas | Soft Tissue Sarcoma | WBSCR26 | 0.05 | 0.03 | blup | 5 | 0.05 | 8.2e-04 | 5.3 | -5.4 | 5.9e-08 | -0.88 | 0.00 | 0.94 | FALSE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | WBSCR26 | 0.06 | 0.07 | lasso | 3 | 0.06 | 1.4e-05 | 5.3 | -5.4 | 8.5e-08 | -0.86 | 0.00 | 1.00 | FALSE |
| 5 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | WBSCR26 | 0.15 | 0.20 | lasso | 2 | 0.20 | 3.1e-08 | 5.0 | -5.3 | 9.2e-08 | -0.93 | 0.00 | 1.00 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | ABHD11 | 0.03 | 0.03 | lasso | 3 | 0.03 | 1.0e-03 | 5.3 | -5.3 | 9.8e-08 | -0.86 | 0.00 | 0.89 | FALSE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | WBSCR26 | 0.24 | 0.26 | enet | 3 | 0.28 | 6.5e-27 | 5.0 | -5.2 | 2.5e-07 | -0.94 | 0.00 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | WBSCR26 | 0.08 | 0.10 | lasso | 3 | 0.09 | 1.0e-10 | 5.0 | -5.1 | 2.8e-07 | -0.96 | 0.00 | 1.00 | FALSE |
| 1 | GTEx | Brain Caudate basal ganglia | WBSCR27 | 0.34 | 0.44 | lasso | 4 | 0.46 | 8.4e-15 | 4.8 | 5.1 | 2.9e-07 | 0.93 | 0.04 | 0.96 | FALSE |