[Hub]/) : Traits : Ulcerative Colitis (UC) : ← →

chr7:106,847,492-108,340,749

Best TWAS P=5.96e-20 · Best GWAS P=4.1e-21 conditioned to 0.000362

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DLD 0.17 0.14 bslmm 510 0.16 1.5e-18 -8.3 -7.9 3.0e-15 0.78 0.98 0.02 FALSE
2 GTEx Brain Cerebellar Hemisphere DLD 0.24 0.06 enet 16 0.05 1.7e-02 7.2 -8.7 2.3e-18 0.78 0.03 0.91 FALSE
3 GTEx Brain Frontal Cortex BA9 DLD 0.21 0.13 lasso 4 0.13 2.8e-04 -7.2 -8.1 7.2e-16 0.76 0.04 0.80 FALSE
4 GTEx Brain Hypothalamus DLD 0.31 0.04 enet 10 0.04 4.6e-02 8.3 -8.8 1.7e-18 0.61 0.13 0.54 FALSE
5 GTEx Cells Transformed fibroblasts CTB-13F3.1 0.10 0.04 enet 14 0.04 3.2e-04 -8.1 -6.3 3.2e-10 0.66 0.05 0.90 FALSE
6 GTEx Testis DLD 0.11 0.12 lasso 2 0.06 1.1e-03 -8.2 -8.2 2.7e-16 0.82 0.08 0.69 FALSE
7 NTR Blood DLD 0.04 0.02 lasso 2 0.02 2.2e-08 -8.3 -8.3 9.7e-17 0.86 0.45 0.55 FALSE
8 ROSMAP Brain Pre-frontal Cortex LAMB1 0.06 0.05 enet 14 0.05 3.3e-07 -8.1 7.0 3.1e-12 -0.77 0.72 0.27 FALSE
9 ROSMAP Brain Pre-frontal Cortex DLD 0.12 0.12 lasso 8 0.15 2.1e-18 8.3 -9.1 6.0e-20 0.80 0.95 0.05 TRUE
10 YFS Blood DLD 0.02 0.01 bslmm 508 0.01 2.3e-04 -8.2 7.6 2.4e-14 -0.82 0.07 0.93 FALSE
11 The Cancer Genome Atlas Bladder Urothelial Carcinoma DLD 0.05 0.04 blup 64 0.04 2.0e-04 8.7 -7.1 1.3e-12 0.42 0.28 0.21 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma DLD 0.09 0.12 blup 64 0.11 2.5e-12 8.3 -7.7 9.8e-15 0.50 0.97 0.03 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma LAMB1 0.03 0.01 blup 92 0.02 7.7e-03 1.8 -6.7 2.1e-11 0.50 0.04 0.28 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma SLC26A3 0.09 0.03 lasso 4 0.06 2.4e-06 1.3 5.4 8.0e-08 -0.74 0.05 0.94 FALSE