[Hub]/) : Traits : Ulcerative Colitis (UC) : ← →

chr7:106,847,492-108,340,749

Best TWAS P=5.96e-20 · Best GWAS P=4.1e-21 conditioned to 0.000362

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	ROSMAP	Brain Pre-frontal Cortex	DLD	0.12	0.12	lasso	8	0.15	2.1e-18	8.3	-9.1	6.0e-20	0.80	0.95	0.05	TRUE
4	GTEx	Brain Hypothalamus	DLD	0.31	0.04	enet	10	0.04	4.6e-02	8.3	-8.8	1.7e-18	0.61	0.13	0.54	FALSE
2	GTEx	Brain Cerebellar Hemisphere	DLD	0.24	0.06	enet	16	0.05	1.7e-02	7.2	-8.7	2.3e-18	0.78	0.03	0.91	FALSE
7	NTR	Blood	DLD	0.04	0.02	lasso	2	0.02	2.2e-08	-8.3	-8.3	9.7e-17	0.86	0.45	0.55	FALSE
6	GTEx	Testis	DLD	0.11	0.12	lasso	2	0.06	1.1e-03	-8.2	-8.2	2.7e-16	0.82	0.08	0.69	FALSE
3	GTEx	Brain Frontal Cortex BA9	DLD	0.21	0.13	lasso	4	0.13	2.8e-04	-7.2	-8.1	7.2e-16	0.76	0.04	0.80	FALSE
1	CommonMind	Brain Pre-frontal Cortex	DLD	0.17	0.14	bslmm	510	0.16	1.5e-18	-8.3	-7.9	3.0e-15	0.78	0.98	0.02	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	DLD	0.09	0.12	blup	64	0.11	2.5e-12	8.3	-7.7	9.8e-15	0.50	0.97	0.03	FALSE
10	YFS	Blood	DLD	0.02	0.01	bslmm	508	0.01	2.3e-04	-8.2	7.6	2.4e-14	-0.82	0.07	0.93	FALSE
11	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	DLD	0.05	0.04	blup	64	0.04	2.0e-04	8.7	-7.1	1.3e-12	0.42	0.28	0.21	FALSE
8	ROSMAP	Brain Pre-frontal Cortex	LAMB1	0.06	0.05	enet	14	0.05	3.3e-07	-8.1	7.0	3.1e-12	-0.77	0.72	0.27	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	LAMB1	0.03	0.01	blup	92	0.02	7.7e-03	1.8	-6.7	2.1e-11	0.50	0.04	0.28	FALSE
5	GTEx	Cells Transformed fibroblasts	CTB-13F3.1	0.10	0.04	enet	14	0.04	3.2e-04	-8.1	-6.3	3.2e-10	0.66	0.05	0.90	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	SLC26A3	0.09	0.03	lasso	4	0.06	2.4e-06	1.3	5.4	8.0e-08	-0.74	0.05	0.94	FALSE