Best TWAS P=6.41e-10 · Best GWAS P=3.43e-11 conditioned to 0.0126
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PARK7 | 0.05 | 0.00 | bslmm | 423 | 0.01 | 1.2e-02 | -5.9 | 5.3 | 1.2e-07 | -0.63 | 0.05 | 0.72 | FALSE |
| 2 | NTR | Blood | PARK7 | 0.02 | 0.01 | lasso | 3 | 0.01 | 1.4e-05 | -5.9 | -6.1 | 9.4e-10 | 0.87 | 0.04 | 0.96 | FALSE |
| 3 | YFS | Blood | PARK7 | 0.08 | 0.11 | lasso | 6 | 0.11 | 4.4e-34 | -5.9 | -5.9 | 3.9e-09 | 0.84 | 0.23 | 0.77 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ERRFI1 | 0.01 | 0.01 | blup | 27 | 0.00 | 4.3e-02 | -5.9 | 6.2 | 6.4e-10 | -0.88 | 0.01 | 0.83 | TRUE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PARK7 | 0.02 | 0.01 | blup | 36 | 0.02 | 2.1e-04 | -6.0 | -5.2 | 1.7e-07 | 0.74 | 0.01 | 0.92 | FALSE |
| 6 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | PARK7 | 0.03 | 0.03 | enet | 3 | 0.02 | 1.3e-03 | -5.8 | -5.6 | 1.9e-08 | 0.88 | 0.01 | 0.93 | FALSE |
| 7 | The Cancer Genome Atlas | Lung Adenocarcinoma | PARK7 | 0.03 | 0.03 | lasso | 1 | 0.02 | 5.0e-03 | -5.9 | -5.9 | 3.9e-09 | 0.84 | 0.00 | 0.85 | FALSE |
| 8 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | PARK7 | 0.22 | 0.00 | blup | 35 | 0.03 | 2.2e-02 | -6.0 | -5.3 | 1.3e-07 | 0.63 | 0.00 | 0.51 | FALSE |