Best TWAS P=4.2e-08 · Best GWAS P=1.83e-08 conditioned to 0.0676
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | PRKCB | 0.27 | 0.11 | lasso | 4 | 0.03 | 2.9e-02 | -5.2 | 5.3 | 1.0e-07 | -0.52 | 0.02 | 0.84 | FALSE |
| 2 | GTEx | Artery Aorta | PRKCB | 0.16 | 0.13 | lasso | 4 | 0.10 | 4.0e-06 | -5.5 | -5.5 | 4.2e-08 | 0.85 | 0.01 | 0.99 | TRUE |
| 3 | GTEx | Esophagus Muscularis | PRKCB | 0.29 | 0.26 | lasso | 5 | 0.25 | 1.4e-15 | -5.5 | -5.4 | 6.1e-08 | 0.87 | 0.00 | 1.00 | FALSE |