Hub : Genes

PRKCB

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.2440 0.0370 7.8e-16 0.170 0.159 0.191 0.183 0.182 3.7e-20 6.0e-19 8.8e-23 8.8e-22 1.3e-21
2 GTEx Adrenal Gland 0.2679 0.0991 2.5e-03 0.113 NA 0.004 NA 0.030 7.3e-05 NA 2.3e-01 NA 3.0e-02
3 GTEx Artery Aorta 0.1640 0.0530 5.1e-04 0.128 NA 0.066 NA 0.099 1.6e-07 NA 1.7e-04 NA 4.0e-06
4 GTEx Artery Tibial 0.2550 0.0447 1.2e-13 0.249 NA 0.245 NA 0.262 1.8e-19 NA 3.3e-19 NA 1.3e-20
5 GTEx Colon Sigmoid 0.3250 0.0900 2.4e-03 0.131 NA 0.063 NA 0.100 2.4e-05 NA 2.9e-03 NA 2.2e-04
6 GTEx Colon Transverse 0.1550 0.0590 4.4e-03 0.083 NA 0.039 NA 0.065 8.9e-05 NA 5.7e-03 NA 5.0e-04
7 GTEx Esophagus Muscularis 0.2920 0.0560 3.4e-09 0.263 NA 0.227 NA 0.254 3.7e-16 NA 6.1e-14 NA 1.4e-15
8 GTEx Testis 0.2110 0.0830 7.8e-03 0.000 NA 0.014 NA 0.005 3.3e-01 NA 7.3e-02 NA 1.8e-01
9 METSIM Adipose 0.0835 0.0272 2.2e-04 0.000 0.025 0.022 0.006 0.010 3.2e-01 8.7e-05 2.7e-04 3.3e-02 1.1e-02
10 NTR Blood 0.1257 0.0220 0.0e+00 0.039 0.080 0.092 0.094 0.103 1.2e-12 1.2e-24 3.9e-28 1.1e-28 2.5e-31
11 ROSMAP Brain Pre-frontal Cortex 0.1069 0.0391 5.9e-03 0.002 0.013 -0.002 0.015 -0.002 1.9e-01 7.2e-03 6.2e-01 3.7e-03 8.0e-01
12 YFS Blood 0.2643 0.0312 0.0e+00 0.194 0.222 0.240 0.231 0.238 2.6e-61 4.4e-71 2.9e-77 3.0e-74 9.7e-77
13 TCGA Breast Invasive Carcinoma 0.0839 0.0251 2.3e-06 0.010 0.032 0.032 NA 0.040 3.7e-03 2.8e-07 3.3e-07 NA 9.5e-09
14 TCGA Kidney Renal Clear Cell Carcinoma 0.1316 0.0439 8.8e-04 0.004 0.051 0.061 NA 0.037 9.3e-02 2.1e-06 1.9e-07 NA 4.3e-05
15 TCGA Prostate Adenocarcinoma 0.0963 0.0374 8.3e-05 0.068 0.032 0.064 NA 0.063 1.2e-07 2.4e-04 3.2e-07 NA 3.7e-07

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bipolar Disorder (2018) 2.2 3.5 7.8 -0.7 1.5 -1.8 -2.8 -0.9 -0.8 -1.3 2.3 2.5 1.7 1.8 2.1 2.4 2.3 -1.3
Bipolar Disorder or Schizophrenia 1.0 2.3 5.6 -0.4 0.8 -2.3 -2.4 -1.4 -1.3 -1.9 0.9 0.5 1.3 1.6 1.5 2.3 1.0 -1.6
Depressed Affect (Nagel 2018) 0.4 0.8 1.7 1.2 0.3 1.1 -0.3 0.9 1.1 1.3 -0.6 -1.2 0.6 0.5 0.4 -0.3 1.1 0.9
Depression (Nagel 2018) 0.5 0.7 4.2 -0.3 0.2 -0.0 0.2 -1.1 -0.7 -0.3 -1.4 -1.3 0.2 -2.1 0.0 -0.0 0.5 -0.6
Intelligence (Savage-Jansen 2018) 0.6 1.9 21.9 -4.7 -0.2 -0.3 0.0 -0.5 -0.3 -0.4 1.0 1.8 -0.5 -0.3 -0.7 -0.7 -0.6 -0.3
Neuroticism (Nagel 2018) 0.2 0.5 1.7 -0.2 -0.9 0.8 -0.2 0.6 0.7 0.9 -0.5 -1.3 -0.7 0.4 -0.5 -0.8 0.1 0.5
Schizophrenia (2018) 0.4 0.8 2.2 0.1 -0.2 -1.5 -0.8 -1.1 -1.1 -1.3 -0.7 -1.4 0.4 0.3 0.3 0.9 -0.3 -1.1
Schizophrenia vs Biploar Disorder 1.7 2.2 8.1 -0.6 -0.3 1.4 2.6 0.4 0.8 1.0 -2.3 -2.8 0.4 -1.6 0.2 -1.8 -1.6 0.3
Worry (Nagel 2018) 0.6 1.3 2.5 -0.6 -0.7 -1.2 -0.6 -1.5 -1.6 -1.1 -1.3 -1.6 -0.8 -1.5 -0.8 -0.6 -0.9 -1.2
Alzheimer’s Disease (in mother) 1.1 1.3 4.8 1.9 -0.7 -0.9 -1.6 -0.3 -0.5 -0.7 1.2 0.9 -0.0 2.2 0.2 -1.0 -1.8 -0.3
Alzheimer’s Disease (in father) 0.5 0.6 1.7 0.1 0.3 1.0 0.4 1.1 1.2 1.1 -0.9 -0.4 -0.7 0.5 -0.0 -0.2 -0.0 1.3
Alzheimer’s Disease (including proxy) 0.9 1.2 5.3 1.7 0.0 -0.2 -1.8 1.0 0.8 0.2 1.4 0.6 -0.5 2.3 0.4 -0.6 -1.2 0.8
Crohns Disease (2017) 1.3 2.9 9.4 -1.1 3.1 -2.2 -2.1 -2.0 -1.6 -1.9 -1.1 0.3 1.8 -0.2 2.2 1.1 0.7 -1.5
Irritable Bowel Disease (IBD) 4.9 11.8 25.6 -1.4 5.1 -5.0 -3.5 -4.5 -4.3 -4.8 -2.2 1.5 3.2 0.8 3.9 1.5 0.3 -3.9
Ulcerative Colitis (UC) 7.1 13.3 30.1 -1.2 5.3 -5.5 -3.0 -4.8 -4.7 -5.4 -2.2 1.9 3.2 1.1 3.9 1.5 -0.2 -4.3
Major Depression (MDD) 2.2 2.6 6.0 -0.4 1.1 -2.0 -2.5 -1.8 -2.2 -1.7 -1.2 1.5 1.7 0.3 1.4 1.1 1.2 -2.2
Reaction Time 1.9 3.7 15.1 0.2 -2.3 0.7 2.2 -0.6 -0.5 0.3 -2.2 -1.8 -1.8 -1.2 -2.0 -3.4 -3.9 -0.3
Verbal and Numeric Reasoning (VNR) 0.3 0.7 4.9 -2.2 -0.5 -0.2 0.5 -0.6 -0.5 -0.4 0.4 0.3 -1.1 -0.3 -1.2 -0.3 -0.5 -0.6
Breast Cancer 0.1 0.2 0.7 -0.7 0.4 0.2 -0.2 0.7 0.7 0.5 0.2 0.0 -0.6 -0.5 -0.2 0.1 0.3 0.9
Ovarian Cancer 3.4 4.6 10.2 0.5 2.4 -3.0 -2.3 -2.5 -3.2 -3.2 -0.4 2.1 1.9 0.4 2.2 1.4 0.9 -2.5
Prostate Cancer 0.9 1.3 3.5 -0.5 0.7 -1.4 -1.3 -1.2 -1.4 -1.3 -0.0 1.9 1.3 0.0 1.0 -0.7 -0.2 -1.8
Age at First Birth 2.7 4.0 12.7 -2.2 -2.8 1.5 3.6 -0.4 -0.1 0.9 -2.1 -2.2 -2.7 -1.6 -3.2 -0.6 -0.8 0.1
Bipolar Disorder (2011) 1.5 1.5 5.0 0.6 0.3 -2.0 -2.2 -1.7 -1.2 -1.7 -0.1 1.9 0.4 1.2 0.8 0.3 0.2 0.0
Body Mass Index (BMI) (2010) 0.7 1.0 2.6 0.5 -1.0 1.5 0.7 1.4 1.5 1.6 0.2 0.6 0.3 1.4 -0.3 -0.7 -0.1 1.0
Coronary Artery Disease (CAD) 0.9 1.0 3.8 -0.5 -0.8 1.5 1.9 0.9 1.3 1.2 0.3 -0.5 -0.3 -1.2 -1.2 0.0 -0.1 1.0
Crohns Disease (2012) 1.7 2.8 6.7 -1.1 2.6 -2.0 -2.2 -1.5 -1.0 -1.7 -0.2 0.6 2.3 -0.6 2.6 1.8 1.0 -1.2
Mean Putamen Volume 0.5 0.6 4.0 0.2 0.2 0.7 0.5 0.3 0.4 0.7 0.0 -0.3 -0.4 -0.7 -0.8 -2.0 -1.2 0.4
Fasting Glucose 0.9 1.1 10.6 0.8 -0.6 -0.1 0.4 -0.0 0.8 0.5 0.1 0.7 0.3 0.8 0.3 -3.2 -1.6 0.0
HbA1C 0.6 0.6 3.1 -0.8 0.9 0.1 -0.0 0.6 0.3 0.1 0.9 0.7 0.0 -0.4 0.4 -1.8 -1.8 -0.2
HDL Cholesterol 0.1 0.2 0.8 -0.7 0.9 0.1 0.5 0.0 0.2 0.1 -0.1 0.0 0.0 0.0 0.6 -0.3 -0.7 0.1
LDL Cholesterol 0.5 0.9 1.8 -0.9 1.1 -1.1 -0.4 -1.3 -1.1 -1.1 -0.3 0.4 1.1 0.8 1.1 0.3 -0.0 -1.3
Lupus 0.5 0.8 2.3 -0.7 -1.2 0.4 -0.5 0.4 0.4 0.7 -0.4 -0.5 -1.4 -1.5 -1.3 -0.0 -0.9 1.0
Neuroticism (2016) 0.5 0.8 2.6 0.2 0.1 0.2 -0.9 1.0 1.1 0.6 1.6 1.2 1.0 0.9 0.8 -0.8 -0.7 0.5
Primary Biliary Cirrhosis 0.6 0.9 3.8 0.3 -1.0 -0.4 -0.4 -0.4 -0.4 -0.3 -0.5 0.6 1.2 1.1 -0.2 1.5 2.0 -1.4
Rheumatoid Arthritis 0.6 0.8 4.2 -0.5 -2.0 0.4 0.3 0.3 -0.1 0.4 1.0 0.2 -0.5 -0.9 -1.1 -0.9 -1.3 0.9
Schizophrenia (2014) 0.7 1.5 3.4 -0.5 0.5 -1.8 -1.7 -1.2 -0.9 -1.5 -0.3 -0.2 1.4 1.6 1.5 1.8 0.6 -1.2
Triglycerides 0.2 0.4 1.7 0.8 -0.2 0.6 0.3 0.4 0.4 0.3 -0.4 -1.3 -0.6 -0.3 -0.7 -0.7 -0.6 0.7
Type 2 Diabetes (T2D) (2012) 0.6 0.7 2.1 0.8 1.5 -0.8 0.1 -0.8 -0.5 -0.8 -0.8 0.3 1.1 -0.0 0.8 -0.9 -1.2 -0.2
Ulcerative Colitis 6.0 8.6 17.7 -1.2 4.0 -4.1 -2.1 -3.8 -3.7 -4.2 -2.2 1.3 3.3 0.8 3.6 0.9 0.2 -3.7
Blood Eosinophil Count 0.4 3.2 15.8 -0.4 -0.6 1.3 2.0 0.0 0.2 0.8 -2.0 -3.1 -0.9 -2.5 0.2 -4.0 -2.1 0.7
Blood Platelet Count 0.1 1.0 3.4 0.2 1.4 -0.9 -1.6 0.2 0.4 -0.5 1.9 0.8 0.4 -0.6 0.9 1.5 0.9 -0.4
Blood Red Count 0.1 0.9 2.2 0.6 0.1 1.1 0.2 1.5 1.2 1.4 0.2 0.1 1.1 1.3 1.1 -0.5 0.1 1.1
Blood White Count 0.6 4.3 16.8 1.2 -2.0 2.0 1.9 1.2 1.6 1.8 0.1 -2.4 -4.1 -1.5 -2.2 -2.2 -2.5 1.9
Heel T-Score 0.2 1.3 10.3 -0.1 1.0 -0.8 -1.4 0.2 0.0 -0.5 3.2 1.1 0.4 1.2 1.2 0.9 0.4 -0.4
BMI 1.0 6.0 16.2 -1.7 -1.5 3.4 1.0 3.8 4.0 3.8 0.3 0.3 -0.7 3.0 -0.7 0.3 2.4 3.3
Height 0.1 1.0 4.5 0.3 0.2 0.4 -0.3 1.2 1.3 0.5 0.6 -1.5 -0.3 -2.1 -0.5 1.3 1.5 0.1
Waist Hip Ratio (WHR) 0.1 0.6 1.5 -0.1 0.3 -0.9 -0.8 -0.6 -0.7 -0.9 0.8 0.2 0.7 -0.1 0.6 1.2 1.2 -1.1
Systolic Blood Pressure 0.4 2.2 8.3 1.0 2.9 -1.6 -1.7 -0.9 -1.2 -1.4 2.2 1.2 1.6 0.5 2.2 0.0 -0.7 0.2
Smoking Status 0.3 0.7 1.8 0.3 0.6 -1.2 -1.0 -0.9 -1.3 -1.2 -0.5 -0.5 -0.1 0.3 0.5 -0.5 -1.0 -1.2
Allergy or Eczema 2.5 6.5 15.3 -0.5 -2.0 1.9 3.2 -0.5 -0.0 1.2 -3.3 -3.9 -3.1 -3.7 -2.4 -3.9 -2.8 0.2
Cardiovascular Disease 0.1 0.5 1.8 0.7 1.1 -0.0 0.1 -0.2 0.2 0.3 -0.3 1.0 1.2 0.8 1.3 -0.6 0.0 0.4
Hypothyroidism (self reported) 1.6 3.7 9.9 -0.0 -2.9 1.6 2.0 1.2 1.3 1.6 1.9 -2.3 -2.8 -2.1 -3.2 -0.6 -1.0 1.2
Respiratory disease 0.3 0.8 5.0 0.5 0.2 0.0 0.6 0.1 -0.1 -0.2 1.3 -0.7 -0.7 -0.8 -0.2 -2.2 -1.6 -0.1
Type 2 Diabetes (T2D) (2018) 0.3 0.5 1.5 0.5 1.0 0.6 -0.1 0.5 0.7 0.6 -1.2 -0.1 0.5 0.6 1.2 -0.6 0.5 0.5
Lung FEV1/FVC ratio 0.3 1.3 6.4 1.7 -0.6 0.1 -1.0 0.2 0.7 0.5 0.1 2.1 0.3 2.5 0.1 0.3 1.8 0.6
Lung FVC 0.1 0.3 2.1 0.3 0.6 0.4 -0.5 -0.1 0.2 0.4 -0.7 0.4 0.7 1.4 0.6 -0.3 0.1 0.0
Neuroticism 0.5 1.3 5.5 -0.3 -1.6 1.1 0.6 0.4 0.9 1.2 -1.8 -2.3 -1.2 -0.2 -1.0 -1.1 -0.4 0.4
Chronotype (morning person) 0.2 0.6 2.2 -1.5 0.6 0.7 0.9 0.3 0.4 0.5 -0.4 -1.0 -0.2 -1.4 -0.1 0.1 -0.7 0.8
Hair Pigment 0.1 1.8 4.2 1.4 -0.6 1.9 1.4 2.0 2.0 1.8 1.4 -0.2 -0.1 0.1 -0.6 0.6 1.3 1.8
Tanning 0.1 1.2 3.2 1.8 1.1 -1.4 -1.3 -0.8 -1.3 -1.4 -0.1 0.7 1.3 -0.5 1.1 0.2 0.3 -1.1
Hand grip strength (left) 0.4 1.0 6.3 2.5 -0.6 0.3 0.2 0.5 0.4 0.3 1.3 -1.1 -0.1 0.8 -0.1 0.9 1.7 0.4
Number of treatments/medications taken 0.5 0.9 2.2 0.8 0.2 -1.5 -1.4 -1.2 -1.2 -1.3 -0.6 1.1 0.2 0.2 0.1 -0.3 -0.2 -1.4
Average weekly spirits intake 1.3 1.6 6.5 0.5 1.8 -1.8 -2.6 -1.2 -1.3 -1.4 -0.5 1.5 -0.0 1.0 0.5 1.1 0.3 -1.0
Sensitivity / hurt feelings 0.7 1.2 4.3 0.5 0.2 1.0 -1.1 1.8 1.7 1.4 0.1 0.6 0.6 2.1 0.8 -0.3 0.7 1.0
Frequency of depressed mood in last 2 weeks 0.5 0.6 5.2 0.6 -0.0 0.3 0.6 -0.1 0.3 0.1 -0.2 -1.5 -0.8 -2.3 -0.2 0.8 0.2 -0.0
Hearing difficulty/problems: Yes 0.6 0.9 4.0 -2.0 0.1 0.3 0.3 0.9 0.8 0.5 1.8 0.9 -0.2 -0.6 -0.1 -1.1 -1.4 -0.1
Relative age of first facial hair 1.0 2.1 6.9 1.9 2.6 -1.7 -1.5 -1.1 -1.6 -1.8 1.3 0.0 1.4 0.4 1.5 -0.7 -1.2 -1.2
Other serious medical condition/disability diagnosed by doctor 0.7 0.9 2.5 0.6 1.3 -1.2 -1.6 -0.6 -0.7 -1.0 -0.3 0.1 1.4 -0.2 1.5 0.6 0.1 -0.6
Ever used hormone-replacement therapy (HRT) 0.3 0.4 2.1 -1.4 -0.7 -0.3 -1.4 0.3 0.4 -0.0 0.6 0.5 0.5 0.1 0.2 -0.2 0.2 -0.6
Ever had hysterectomy (womb removed) 0.9 1.1 4.3 0.3 -0.3 1.1 0.4 1.4 2.1 1.5 0.6 0.7 1.3 1.2 0.7 -0.1 0.6 1.0
Systolic blood pressure, automated reading 0.4 1.2 4.5 0.7 1.5 -1.2 -2.1 -0.7 -1.0 -0.9 1.4 0.5 1.2 1.4 1.3 -0.2 -0.2 -0.3
Eye problems/disorders: Diabetes related eye disease 0.4 0.4 1.7 0.6 -0.7 -0.3 0.1 -0.7 -0.7 -0.4 -0.6 -0.4 0.2 -1.3 -0.1 -0.0 0.6 -1.1
Angina 1.3 1.7 5.1 0.8 -0.3 -1.2 0.3 -1.4 -1.0 -1.4 -1.4 -1.5 -2.3 -1.3 -1.6 -0.4 -1.7 -1.2
Medication for hormone replacement therapy 0.4 0.5 1.8 0.2 0.5 -0.0 -0.3 0.0 0.2 0.2 -1.4 -1.1 1.3 0.6 1.1 -0.4 0.5 0.5
Vitamin and mineral supplements 0.9 1.2 4.6 -2.1 0.1 0.6 -0.2 1.1 1.3 0.7 0.5 0.7 0.8 1.0 0.6 -2.1 -1.5 0.8
Supplements: Zinc 2.0 2.2 5.6 -0.3 2.2 -1.2 -1.5 -0.7 -0.8 -1.1 0.7 1.8 2.0 0.9 2.4 2.2 1.7 -0.2
Medication: Co-codamol 2.4 2.7 6.2 -2.5 2.5 -1.7 -1.2 -1.5 -1.9 -1.8 -0.7 1.4 1.7 0.5 2.1 1.1 0.4 -2.0
Medication: Metformin 0.4 0.6 1.8 0.8 0.5 -0.0 -1.3 1.0 0.9 0.3 0.8 -0.1 -0.2 1.4 0.6 1.0 0.9 0.4
Diabetes (father) 1.7 2.1 5.2 -1.5 0.5 2.0 1.3 2.2 2.3 2.1 0.7 0.4 -0.6 1.5 -0.3 -0.8 -0.4 2.1
Diabetes (mother) 0.3 0.4 1.3 -0.1 -0.1 0.7 0.4 0.5 0.8 0.8 -1.2 -1.1 -0.4 0.1 -0.5 0.3 -0.2 0.7
Severe depression (siblings) 0.7 0.7 4.2 1.4 0.3 0.4 0.2 0.9 0.9 0.5 -0.5 -0.3 0.4 0.6 0.3 2.0 1.4 0.4
Pack years adult smoking proportion 0.8 1.2 4.1 -1.3 -0.6 1.4 2.0 1.3 0.7 1.1 1.0 -1.0 0.2 -1.3 -0.5 -0.6 -1.2 0.6
Impedance of leg (right) 0.7 3.3 8.2 1.6 1.7 -2.4 -1.4 -2.4 -2.9 -2.6 -0.6 -0.2 2.0 -1.6 1.5 0.0 -0.7 -2.5
Leg fat-free mass (left) 0.7 3.9 11.1 -1.2 -1.6 2.8 1.2 3.0 3.3 3.0 1.2 -0.0 -1.3 0.9 -1.3 0.4 1.7 2.8
Trunk fat percentage 0.3 1.0 4.1 -1.7 0.4 0.9 -0.4 1.3 1.2 1.0 -0.1 0.6 0.8 0.8 0.5 0.5 2.0 0.7
Hand grip strength (right) 0.5 1.4 7.3 2.7 -0.2 -0.2 -0.5 0.0 -0.0 -0.1 2.3 0.2 0.2 1.2 0.2 1.6 1.9 -0.3
Townsend deprivation index at recruitment 0.5 0.7 3.9 -1.8 0.8 -0.7 -0.7 0.1 -0.3 -0.5 0.1 -0.6 -0.8 -1.1 -0.1 2.0 0.2 -0.1
Current tobacco smoking 0.7 1.1 2.8 -1.5 1.3 -1.2 -1.7 -0.6 -1.4 -1.1 0.7 0.0 0.6 0.2 0.9 1.2 0.2 -1.2
Average weekly fortified wine intake 0.9 1.0 2.3 0.1 -0.4 1.2 1.2 1.2 1.3 1.2 0.3 0.5 -1.0 -0.9 -1.2 -1.1 -1.0 1.5
Maternal smoking around birth 0.8 1.1 6.0 -1.0 1.3 -1.0 -1.8 0.7 0.2 -0.7 2.5 -0.3 0.1 0.0 1.0 1.1 -0.1 0.3
Fed-up feelings 1.2 2.3 5.3 1.3 -0.3 2.3 1.2 2.1 2.2 2.3 -0.5 -2.1 -0.5 0.3 -0.3 -1.4 -0.4 1.9
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.1 7.2 -1.7 0.0 0.1 0.7 -0.8 -0.4 -0.1 -1.4 -1.5 -0.7 -2.7 -0.6 0.4 0.0 -0.5
Relative age voice broke 1.3 2.0 8.2 0.1 2.9 -1.3 -1.7 -0.5 -0.7 -1.1 1.9 1.4 2.0 0.0 2.0 1.0 0.4 -0.4
Taking other prescription medications 0.6 1.0 2.0 -0.3 -0.1 -1.1 -0.8 -1.1 -1.1 -1.2 -0.6 -1.0 -0.3 -1.2 -0.3 -1.3 -1.3 -1.4
Age when periods started (menarche) 1.6 3.9 10.6 1.7 1.0 -3.0 -1.6 -2.5 -2.7 -3.1 -0.8 0.4 1.1 -1.6 0.7 -1.2 -1.6 -3.2
Bilateral oophorectomy (both ovaries removed) 0.5 0.5 2.3 0.3 -0.3 0.9 -0.2 1.2 1.5 1.3 -0.2 0.1 0.5 0.0 0.2 -0.5 0.4 0.9
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.4 2.0 -0.1 -0.2 -0.5 -0.6 -0.3 -0.2 -0.4 0.9 -0.2 0.8 -0.4 0.8 0.7 0.9 -1.4
Tinnitus: Yes, but not now, but have in the past 0.9 1.0 4.2 -0.6 -1.8 -0.0 0.5 -0.0 -0.2 0.1 -0.4 -0.3 -0.9 -0.5 -0.9 -1.9 -2.0 -0.6
Qualifications: CSEs or equivalent 0.7 0.9 5.3 -0.6 0.6 -0.6 0.3 -1.4 -1.3 -0.6 -2.3 0.0 0.3 0.0 -0.1 -1.1 -0.3 -1.0
Serious illness, injury or assault to yourself 2.0 2.4 11.2 0.2 0.4 -1.6 -1.1 -1.6 -2.0 -1.7 -3.4 -1.5 0.3 -2.5 -0.5 -0.3 -0.5 -1.7
High blood pressure 0.2 0.5 1.6 0.1 -0.4 1.0 0.4 0.8 1.2 1.3 -0.7 -0.5 0.0 0.6 0.1 -0.3 0.7 1.1
Hayfever, allergic rhinitis or eczema 1.1 2.4 7.1 -0.8 -0.8 1.3 2.3 -0.4 -0.2 0.7 -1.9 -1.9 -1.3 -2.5 -1.1 -2.7 -1.7 0.3
Multivitamins +/- minerals 0.9 1.1 4.8 1.2 1.4 -1.0 -0.5 -0.9 -1.1 -1.1 -0.4 -0.1 -0.2 -0.9 0.2 2.2 1.4 -1.2
Stomach or abdominal pain in last month 0.4 0.6 5.0 0.2 0.8 -0.8 -2.2 0.3 -0.3 -0.3 0.9 0.3 0.2 0.1 0.6 0.5 0.4 0.2
Supplements: Glucosamine 1.0 1.3 3.9 -0.7 -0.5 -1.0 0.5 -1.9 -1.7 -1.4 -2.0 0.2 -0.4 -0.7 -0.9 0.8 0.9 -1.5
Diverticular disease/diverticulitis (self-reported) 0.8 1.0 7.4 -1.3 -0.2 -0.2 -0.7 0.5 0.7 0.0 2.7 1.8 0.7 0.2 0.6 -0.5 0.1 0.6
Medication: Atenolol 1.3 1.6 6.1 0.9 -0.8 0.7 1.8 0.6 0.5 0.5 0.4 -0.9 -2.0 -0.9 -1.9 -1.3 -2.5 0.8
Medication: Levothyroxine sodium 0.6 1.0 4.2 -0.5 -1.6 -0.3 0.1 0.0 0.0 -0.1 0.6 -0.5 -1.8 -1.7 -2.0 -0.7 -1.1 -0.3
Sitting height 0.3 2.3 5.9 1.6 -0.8 2.0 1.0 2.0 2.4 2.0 0.6 -1.9 -0.7 -0.9 -0.9 -0.3 0.7 2.4
Chronic bronchitis/emphysema (father) 0.4 0.5 1.4 0.7 0.4 -0.8 -1.2 -0.1 -0.5 -0.6 0.6 1.1 0.5 1.0 0.6 0.4 0.8 -0.7
High blood pressure (mother) 1.4 2.0 5.9 0.0 2.4 -1.8 -0.9 -1.9 -1.3 -1.7 -0.8 0.7 1.1 -0.1 1.6 -1.4 -2.0 -1.1
Body mass index (BMI) 0.7 3.1 7.4 -1.9 -1.1 2.1 0.3 2.6 2.7 2.4 0.4 0.7 -0.4 2.3 -0.5 0.6 2.2 2.2
Impedance of leg (left) 0.7 3.5 8.0 2.0 1.8 -2.4 -1.5 -2.3 -2.8 -2.6 -0.8 -0.4 1.8 -1.3 1.5 -0.3 -0.9 -2.7
Leg predicted mass (left) 0.7 4.0 11.2 -1.2 -1.6 2.8 1.3 3.0 3.3 3.0 1.2 0.0 -1.2 0.9 -1.3 0.4 1.6 2.9
Trunk fat mass 0.4 1.6 4.3 -1.6 -0.5 1.6 0.1 1.9 2.1 1.8 -0.0 0.2 -0.0 1.1 -0.3 0.4 2.0 1.5
Waist circumference 0.6 2.2 7.5 -1.8 -0.9 1.5 -0.2 2.0 2.1 1.8 0.7 0.9 -0.1 1.5 -0.4 1.1 2.7 1.6
Number of incorrect matches in round 0.4 0.7 3.7 1.9 0.6 -0.1 -0.0 -0.2 0.1 0.0 -0.3 0.5 1.9 0.7 1.1 -0.3 0.3 0.5
Past tobacco smoking 0.3 0.6 1.9 -0.2 1.4 0.4 0.3 0.6 0.5 0.4 0.7 1.0 1.0 -0.3 0.8 0.9 1.1 0.7
Alcohol usually taken with meals 1.0 1.6 4.6 0.5 -0.7 1.8 0.3 2.1 2.1 1.9 1.6 0.1 0.4 -0.7 0.5 -1.1 -0.3 1.5
Nervous feelings 0.7 1.3 6.3 -0.0 -1.0 -0.4 0.1 -0.7 -0.8 -0.2 -0.6 -1.4 -1.6 -1.1 -1.1 -1.8 -2.5 -0.2
Frequency of tenseness / restlessness in last 2 weeks 0.6 0.9 5.2 -0.5 -0.0 -0.7 -0.5 -0.8 -0.7 -0.6 -0.0 -1.4 -1.3 -2.3 -0.6 0.3 -0.8 -0.9
Hearing difficulty/problems with background noise 0.4 0.7 2.0 -1.4 -0.6 -0.4 -0.7 0.1 -0.3 -0.4 1.4 0.8 -1.4 -0.6 -0.9 -0.2 -1.0 -0.8
Hair/balding pattern: Pattern 2 0.9 1.1 3.9 1.9 0.7 0.3 -0.0 0.7 0.3 0.3 0.1 0.1 2.0 -1.0 1.6 0.7 1.8 0.9
Had menopause 1.1 1.4 5.3 -0.6 -2.3 1.3 0.5 1.0 1.2 1.4 -1.4 -1.3 -0.5 -0.3 -1.6 -0.8 -0.5 0.7
Had other major operations 0.8 0.9 4.5 0.0 -1.2 0.5 -0.3 0.6 0.8 0.6 -1.0 -0.5 -2.1 0.4 -2.1 0.1 0.1 0.7
Forced vital capacity (FVC) 0.1 0.4 1.2 0.3 0.5 1.0 0.5 0.7 0.8 0.8 -0.6 -0.5 0.8 0.2 0.5 -1.1 0.1 0.6
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.6 4.0 -0.2 -0.4 0.4 0.1 0.6 0.8 0.6 2.0 -1.0 0.3 -1.1 0.4 0.0 0.0 -0.3
Ever unenthusiastic/disinterested for a whole week 1.5 1.9 4.4 0.5 0.4 -1.9 -0.6 -2.0 -2.0 -2.0 -1.1 -0.8 0.7 -2.1 0.9 -0.5 -1.0 -1.9
Qualifications: None of the above 0.1 0.2 0.7 -0.7 -0.1 -0.2 -0.3 0.5 0.1 -0.1 0.1 -0.4 -0.7 0.3 -0.3 0.7 -0.8 -0.1
Financial difficulties in last 2 years 2.0 2.6 6.6 0.1 1.6 -2.6 -1.9 -2.0 -2.4 -2.4 -1.2 0.3 0.5 -2.0 0.9 0.5 -0.3 -2.2
Mouth/teeth dental problems 0.8 1.2 3.6 -0.4 0.9 -1.1 0.3 -1.9 -1.9 -1.5 -1.5 -0.2 1.1 -0.1 0.8 -0.9 -0.9 -0.5
Heart attack 0.8 1.0 4.9 2.2 -0.9 0.9 0.6 1.0 0.9 0.9 0.2 -0.9 -1.3 -0.1 -1.2 -0.4 -1.1 0.9
Allergy 0.8 1.8 6.6 -0.2 0.5 -0.1 -1.8 1.2 0.9 0.4 1.7 2.0 1.0 2.6 0.6 2.0 1.3 0.6
Pain all over the body in last month 1.9 2.0 5.1 -0.9 1.9 -1.9 -2.3 -1.0 -1.4 -1.8 0.4 1.0 1.7 -1.3 2.1 0.5 -0.4 -0.1
Diabetes (self-reported) 0.6 0.9 2.4 0.1 -0.3 1.5 0.7 1.6 1.5 1.5 -0.4 -1.1 -0.7 -0.6 -0.3 0.2 0.4 0.8
Hayfever/allergic rhinitis (self-reported) 0.4 0.6 3.0 0.0 -0.5 0.4 1.2 -0.3 -0.3 0.2 -0.6 -0.4 -0.2 -1.7 -0.1 -1.6 -0.7 0.2
Medication: Ramipril 0.8 1.0 4.3 2.0 -1.4 0.4 0.4 0.3 0.5 0.4 0.5 -0.1 -0.9 0.7 -0.5 -1.5 -2.1 -0.4
Medication: Simvastatin 0.5 0.8 3.8 1.9 -0.3 -0.9 -0.5 -0.3 0.0 -0.5 0.3 0.8 0.3 1.8 0.4 -1.1 -0.7 -0.4
Fluid intelligence score 0.8 1.7 10.6 -3.2 -1.4 0.9 1.8 0.4 0.6 0.7 1.5 0.3 -1.3 -0.7 -1.6 -0.8 -0.8 0.3
Illnesses of siblings 0.3 0.5 4.6 -0.6 0.1 -0.5 -0.2 -0.3 -0.7 -0.5 0.5 0.3 -0.0 -2.1 -0.1 0.1 -0.3 -0.6
Neuroticism score 0.4 0.8 1.9 0.7 -1.0 1.0 -0.5 1.4 1.4 1.3 0.1 -1.3 -0.7 -0.1 -0.4 -0.6 -0.3 0.9
Weight 0.8 4.1 11.6 -1.6 -1.4 2.8 0.8 3.1 3.4 3.1 0.5 -0.2 -0.8 1.4 -1.0 0.6 2.3 2.8
Impedance of arm (right) 0.7 3.0 7.5 -0.8 2.5 -1.8 -0.7 -2.2 -2.7 -2.2 -1.4 -0.2 1.7 -2.5 1.4 -0.0 -0.9 -2.0
Arm fat percentage (right) 0.4 1.7 4.7 -2.2 -0.3 1.5 -0.0 1.8 1.8 1.7 -0.3 0.8 0.3 1.4 0.1 0.1 1.8 1.5
Trunk fat-free mass 1.2 7.1 20.2 0.5 -3.1 3.5 1.8 3.9 4.5 4.0 1.2 -0.9 -2.4 1.7 -2.5 0.1 1.1 3.5
Hip circumference 0.4 1.9 4.6 -1.2 -1.1 1.8 0.3 2.0 2.1 1.9 0.1 0.7 -0.5 1.3 -0.7 0.3 2.1 1.7
Time employed in main current job 0.4 0.5 2.6 0.9 0.6 -0.4 -0.4 -0.7 -0.3 -0.4 -0.3 1.6 0.7 0.2 0.9 -0.2 -0.9 -0.7
Alcohol intake versus 10 years previously 0.8 1.2 3.5 0.2 -0.2 -1.4 0.1 -1.9 -1.5 -1.5 -1.6 -0.9 -0.4 -0.5 -0.2 -1.0 -1.5 -1.3
Father’s age at death 0.3 0.4 1.5 0.0 -1.1 0.5 0.4 0.4 0.5 0.6 0.1 0.4 0.1 0.5 -1.2 0.6 0.8 -0.4
Worrier / anxious feelings 0.3 0.6 2.2 -0.6 -1.5 0.3 -0.0 0.5 0.5 0.5 -0.2 -1.2 -1.1 -1.5 -1.1 0.1 0.4 0.3
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.6 2.7 -0.9 -0.8 0.3 0.6 -0.3 -0.2 0.2 -1.0 -1.3 -0.9 -1.6 -0.8 0.1 -0.1 0.3
Falls in the last year 0.8 1.1 2.9 0.7 -0.9 -1.2 -0.0 -1.6 -1.3 -1.2 -1.6 -0.6 -0.1 -0.7 -0.9 -0.4 -0.7 -1.7
Hair/balding pattern: Pattern 3 0.3 0.5 1.6 0.1 -0.1 0.6 0.5 0.9 1.0 0.6 0.2 -0.4 -0.9 0.6 -0.4 1.2 0.2 1.1
Number of live births 0.8 1.2 9.5 3.1 0.3 0.5 -0.3 0.7 1.1 0.6 -0.5 -1.4 -0.2 -0.5 0.3 0.8 0.8 1.2
Forced expiratory volume in 1-second (FEV1) 0.1 0.4 1.4 0.6 -0.0 0.9 0.3 0.6 0.7 0.8 -0.5 -0.2 0.1 0.7 -0.2 -1.2 -0.1 0.6
Pulse rate 0.3 0.5 2.3 0.9 1.5 0.4 -1.0 0.9 0.8 0.7 0.2 0.6 -0.1 0.7 0.6 -0.1 0.6 0.7
Happiness 0.7 0.8 3.2 -1.8 -0.6 0.9 0.0 0.9 0.9 1.1 0.4 0.8 -1.0 0.5 -0.6 -0.1 -0.4 1.4
Noisy workplace 0.7 0.8 4.0 -0.3 0.1 0.3 -0.7 0.5 0.2 0.3 -0.5 -1.1 -0.5 -1.3 -0.3 2.0 1.9 0.4
Qualifications: A levels/AS levels or equivalent 0.2 0.5 1.8 0.5 0.4 -0.4 -0.3 -0.7 -0.5 -0.5 0.6 0.2 -1.2 -0.5 -0.1 -1.3 -1.4 -0.3
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 5.0 -0.0 2.2 0.2 0.5 -0.1 0.1 0.0 -0.7 0.7 1.2 0.2 1.3 0.5 0.6 0.0
Mouth/teeth dental problems: Dentures 3.0 5.1 17.6 0.9 1.3 0.2 -2.3 2.8 2.4 0.9 4.2 1.5 1.5 1.2 2.0 3.5 3.7 1.4
Asthma 0.6 1.1 4.6 1.7 -0.3 0.0 1.0 0.2 -0.1 -0.1 0.5 -1.9 -0.6 -2.1 -0.3 -1.5 -1.3 0.2
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.8 3.4 1.3 -1.2 0.7 1.4 0.3 0.4 0.6 0.1 -0.7 -0.3 -1.9 -1.0 -0.0 0.4 0.1
Medication: Cholesterol lowering 0.6 1.0 5.3 0.8 0.2 -0.7 -0.3 -0.1 0.0 -0.5 1.0 2.0 -0.2 2.3 0.1 -1.0 -1.4 -0.1
Depression (self-reported) 1.9 2.2 6.7 0.1 1.1 -1.6 -1.9 -1.5 -1.3 -1.5 -0.4 0.0 1.7 -0.5 1.6 2.5 2.6 -0.9
Medication: Lansoprazole 1.8 2.0 5.8 -0.6 1.2 -2.0 -1.0 -1.9 -2.2 -2.1 -0.8 1.1 1.4 0.2 0.8 0.1 0.4 -2.4
Prospective memory result 0.6 0.8 2.2 1.5 -0.5 -0.1 -0.7 0.8 0.3 0.1 1.3 -1.1 0.4 -1.0 0.4 1.2 1.4 0.3
Lung cancer (father) 1.3 1.5 4.9 1.3 -0.9 1.2 1.0 1.1 1.2 1.2 -0.8 -2.2 -0.8 -0.1 -1.2 -1.5 -1.1 1.6
Illnesses of mother 0.3 0.4 1.6 0.6 -1.1 0.5 0.3 0.3 0.1 0.3 -0.7 -0.7 -0.0 -0.5 -0.3 0.2 1.3 -0.4
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.3 3.6 0.9 -0.6 1.9 0.8 1.5 1.6 1.7 0.1 -0.4 -0.1 1.4 -0.5 -1.3 0.2 1.5
Pulse wave Arterial Stiffness index 0.5 0.6 1.3 -0.0 -0.4 0.7 -1.0 1.1 0.9 1.0 -0.6 0.6 -0.3 1.0 -0.8 -0.1 0.4 1.1
Impedance of arm (left) 0.9 4.0 9.5 -1.6 2.8 -2.0 -0.4 -2.7 -3.1 -2.5 -1.0 0.1 1.9 -2.9 1.6 -0.1 -1.0 -2.3
Arm fat mass (right) 0.7 2.8 7.1 -2.2 -1.2 2.2 0.6 2.4 2.7 2.5 0.1 0.4 -0.4 1.6 -0.7 0.2 1.9 2.0
Trunk predicted mass 1.2 6.9 19.5 0.4 -3.1 3.4 1.7 3.8 4.4 3.9 1.3 -0.9 -2.4 1.7 -2.5 0.1 1.1 3.4
Standing height 0.2 2.0 4.9 0.6 -1.2 1.8 1.0 2.0 2.2 1.9 0.8 -1.7 -1.0 -1.4 -1.5 0.1 0.4 1.7
Length of working week for main job 0.6 0.6 4.9 -2.2 0.4 0.6 1.3 0.3 0.5 0.3 -0.1 0.3 -0.2 0.9 0.3 -0.7 -0.5 0.4
Exposure to tobacco smoke at home 0.6 0.7 2.4 -1.1 -0.1 1.2 1.4 0.7 0.7 0.9 0.1 -0.4 0.4 0.2 -0.2 -0.1 0.9 1.5
Breastfed as a baby 0.9 1.2 5.5 0.7 -0.7 1.6 2.3 0.4 0.9 1.2 -1.0 0.1 -0.3 0.5 -0.4 -1.2 -0.9 1.4
Tense / ‘highly strung’ 0.3 0.5 1.9 -0.4 0.1 0.0 -0.7 0.2 -0.0 0.0 -0.0 -1.0 -1.4 -1.4 -0.5 0.6 -0.4 0.7
Seen doctor (GP) for nerves, anxiety, tension or depression 1.0 1.5 6.1 -0.6 0.9 -1.1 -1.3 -0.4 -0.6 -0.8 0.7 0.5 1.2 0.1 1.4 2.5 2.5 -0.6
Hair/balding pattern: Pattern 4 0.5 1.2 3.3 -1.2 -0.2 -1.3 -0.6 -1.6 -1.3 -1.2 -1.1 0.6 -0.8 1.8 -1.0 0.9 0.4 -1.4
Birth weight of first child 0.4 0.8 2.4 -0.2 -0.9 0.7 -0.6 1.0 0.7 0.7 1.3 0.1 -1.6 0.9 -1.1 1.0 0.9 0.3
Peak expiratory flow (PEF) 0.1 0.2 0.9 0.5 1.0 -0.2 -0.1 -0.3 -0.3 -0.4 0.5 0.6 0.4 0.1 0.5 -0.2 -0.3 -0.3
Pulse wave reflection index 0.5 0.7 2.1 0.4 -0.4 -1.1 -1.3 -1.0 -1.4 -1.1 -0.2 0.5 -0.1 0.2 -0.3 0.8 0.1 -1.2
Ever highly irritable/argumentative for 2 days 1.0 1.2 2.6 1.2 0.9 -1.3 -1.0 -1.2 -1.6 -1.5 -0.7 -0.1 0.8 -1.3 0.6 -1.4 -1.3 -0.6
Loud music exposure frequency 0.8 0.9 2.5 -1.2 1.3 -1.2 -0.9 -0.6 -1.0 -1.2 0.7 0.8 0.5 -0.0 0.7 1.6 0.7 -0.8
Qualifications: O levels/GCSEs or equivalent 1.0 1.6 4.3 0.2 1.5 -2.1 -1.2 -1.9 -1.7 -2.0 0.6 1.2 0.3 -0.3 1.1 -0.3 -0.8 -1.3
Mouth/teeth dental problems: Bleeding gums 0.7 0.9 4.6 -0.4 -0.9 0.3 0.5 0.1 0.4 0.5 -0.3 -1.1 -2.1 -0.7 -1.7 -0.7 -1.5 -0.2
Blood clot in the leg (DVT) 0.8 1.1 3.0 -0.1 0.9 -1.7 -0.7 -1.0 -1.3 -1.7 -0.1 1.0 0.8 0.3 1.1 -0.7 -0.7 -1.4
Medication: Paracetamol 0.3 0.5 1.2 0.0 -0.5 0.9 0.2 0.7 0.9 1.0 -0.4 -0.2 -1.1 -0.9 -1.0 0.0 0.2 0.4
Headache pain in last month 0.1 0.3 1.0 0.1 0.1 0.6 -0.1 0.8 0.6 0.6 -0.1 -0.4 -0.3 -1.0 -0.5 -0.3 0.7 -0.1
Medication for cholesterol, blood pressure or diabetes 0.5 0.8 5.1 -0.8 -0.0 0.4 0.7 -0.3 -0.4 -0.0 -1.0 -1.3 0.7 -2.3 -0.0 0.5 1.2 -0.1
Glaucoma (self-reported) 0.3 0.3 1.2 0.5 -0.9 -0.3 -0.4 -0.2 0.1 -0.2 0.5 0.2 1.1 -0.4 0.2 0.4 0.9 -0.9
Gout (self-reported) 0.4 0.6 2.5 1.0 -0.2 -0.5 -1.1 -0.1 -0.3 -0.2 0.6 -0.7 -0.2 -0.9 0.1 1.6 1.3 0.2
Hypothyroidism/myxoedema (self-reported) 1.4 2.7 9.1 -1.1 -2.4 0.5 1.2 0.3 0.5 0.5 0.5 -2.4 -2.8 -2.6 -3.0 0.1 -0.9 0.3
Medication: Amlodipine 0.4 0.5 1.3 -0.3 -1.1 -0.7 -0.0 -0.8 -0.9 -0.7 0.5 0.2 -0.9 1.0 -0.9 0.4 0.4 -0.9
Medication: Ventolin 100micrograms inhaler 0.9 1.1 2.9 1.2 1.1 -1.7 -1.1 -1.0 -1.3 -1.7 0.1 -0.5 0.2 -1.1 0.8 0.5 -0.8 -1.0
Birth weight 0.4 1.0 3.4 -0.4 -1.5 0.7 -0.1 0.4 0.5 0.7 -1.0 -0.1 -1.8 -0.3 -1.8 1.1 1.1 0.5
Chronic bronchitis/emphysema (mother) 1.3 1.5 6.8 -0.6 2.6 -1.1 -0.9 -1.0 -1.5 -1.2 1.0 0.7 1.4 -1.1 1.8 -0.2 -0.9 -0.1
High blood pressure (siblings) 0.1 0.2 0.5 0.1 -0.4 0.4 -0.0 0.5 0.6 0.5 0.1 -0.6 -0.3 0.6 -0.0 0.7 0.2 0.7
Forced vital capacity (FVC), Best measure 0.3 1.1 3.6 0.2 -0.3 1.9 1.1 1.4 1.5 1.6 -0.1 -0.9 0.4 0.7 -0.2 -1.1 0.4 1.5
Body fat percentage 0.3 1.3 5.1 -1.7 0.3 1.0 -0.6 1.5 1.4 1.2 -0.1 0.7 0.8 1.3 0.5 0.5 2.3 0.9
Leg fat percentage (right) 0.3 1.3 6.0 -0.8 0.1 0.4 -1.2 1.1 1.1 0.9 -0.3 0.8 1.1 1.9 0.9 0.6 2.5 0.7
Arm fat-free mass (right) 1.0 5.1 15.7 -0.1 -2.7 3.0 1.1 3.5 4.0 3.4 1.2 -0.4 -1.4 1.6 -1.8 0.2 1.6 3.0
Exposure to tobacco smoke outside home 0.9 1.2 2.9 -1.0 1.2 -1.6 -1.0 -1.4 -1.7 -1.5 -0.1 0.5 1.1 0.1 1.1 0.7 0.3 -1.5
Comparative body size at age 10 0.3 0.7 3.1 0.5 -0.3 -0.9 -1.8 -0.3 -0.6 -0.6 -0.8 0.9 -0.2 0.2 -0.5 1.4 1.1 -1.0
Number of full brothers 0.2 0.3 0.9 0.8 0.1 0.3 0.6 0.1 0.4 0.2 0.2 0.3 -0.2 0.7 -0.1 1.0 0.9 0.2
Worry too long after embarrassment 1.4 2.4 7.0 -0.2 -1.0 2.5 0.9 2.3 2.4 2.6 0.1 -0.8 -0.9 0.9 -0.9 0.3 0.8 2.4
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.6 2.6 0.3 -0.8 0.0 -0.4 0.4 0.4 0.2 1.6 0.2 0.2 -0.0 0.0 1.6 1.6 -0.4
Wheeze or whistling in the chest in last year 0.8 1.5 5.9 0.7 2.3 -0.0 -0.8 1.0 0.3 -0.0 1.4 0.9 2.0 -0.8 2.4 0.6 1.1 0.1
Number of children fathered 0.7 0.8 5.4 2.3 1.2 -0.1 0.5 -0.0 0.5 -0.1 1.0 0.0 0.9 0.1 1.3 -1.1 0.3 -0.3
Reason for reducing amount of alcohol drunk: Health precaution 0.8 0.9 3.3 1.3 -1.6 0.2 -0.3 0.4 0.7 0.5 0.4 0.2 -1.8 -0.4 -1.5 1.7 -0.1 -0.2
Age at first live birth 0.5 1.0 2.8 0.7 -1.5 0.2 0.6 -0.4 -0.1 0.2 -0.4 -0.5 -1.7 -0.7 -1.5 -1.6 -1.6 0.6
Pulse wave peak to peak time 0.5 0.6 1.8 0.3 0.2 -0.7 1.0 -1.1 -0.9 -1.0 0.7 -0.7 0.4 -1.3 0.7 0.2 -0.3 -1.2
Health satisfaction 1.0 1.3 3.3 -1.8 1.2 -1.4 -1.5 -1.0 -1.3 -1.3 -1.0 0.2 0.9 -1.5 0.9 1.2 0.2 -0.4
Shortness of breath walking on level ground 0.3 0.4 2.3 -0.0 1.5 -0.4 -1.2 0.5 0.1 -0.1 -0.4 -0.2 -0.0 -0.2 0.5 -0.3 -0.2 0.9
Qualifications: College or University degree 0.3 0.8 2.1 -0.2 -0.6 0.9 1.4 0.3 0.4 0.6 -0.6 -0.4 -1.2 -0.5 -1.0 -1.4 -1.3 1.4
Eye problems/disorders: None of the above 0.6 0.7 2.0 -1.4 1.4 -0.6 0.4 -1.0 -1.0 -0.7 -0.3 0.1 0.6 -1.3 0.3 0.2 -0.9 -0.3
Mouth/teeth dental problems: Loose teeth 3.5 4.1 11.2 -3.0 1.6 -2.4 -1.1 -2.2 -2.5 -2.7 -0.2 1.2 1.4 -1.3 1.3 2.3 1.3 -3.3
Emphysema/chronic bronchitis 1.3 1.5 2.8 0.7 1.6 -1.2 -1.5 -0.4 -0.9 -1.2 1.2 1.6 1.4 0.7 1.7 1.2 1.5 -0.7
Medication for pain relief, constipation, heartburn 0.3 0.5 2.7 -1.6 0.2 0.0 0.8 -0.1 -0.2 -0.2 1.0 0.1 1.4 0.4 0.9 0.2 0.5 0.1
Neck or shoulder pain in last month 0.2 0.3 1.2 0.4 -0.0 -0.9 -0.5 -0.5 -0.8 -1.1 0.2 -0.0 -0.4 -0.8 -0.3 0.0 -0.7 -0.6
Medication: Blood pressure 0.4 0.8 3.8 -0.1 -0.3 0.1 -0.0 0.6 0.6 0.4 1.0 1.3 -0.4 1.9 0.1 -1.3 -1.3 0.6
Angina (self-reported) 1.2 1.6 4.3 1.2 -0.3 -1.1 0.3 -1.3 -0.9 -1.2 -1.5 -1.7 -2.1 -1.2 -1.4 -0.3 -1.7 -1.1
Migraine (self-reported) 0.4 0.5 1.7 -0.9 -0.3 0.5 0.5 -0.4 -0.1 0.5 -1.1 0.3 -0.8 1.0 -1.3 -0.0 1.0 0.3
Medication: Ibuprofen 0.6 0.7 3.9 2.0 -1.0 0.7 1.1 0.7 0.6 0.7 0.6 -0.5 -0.3 -1.0 -0.9 -0.1 0.3 0.5
Medication: Allopurinol 0.7 1.0 3.1 1.6 -0.0 -0.6 -1.4 -0.2 -0.2 -0.3 0.0 -0.9 0.7 -1.7 0.6 1.5 1.8 0.2
Medication: Omeprazole 0.4 0.5 1.2 1.1 0.3 -1.0 -1.1 -0.5 -0.6 -0.7 -0.5 -0.3 0.5 -1.0 0.5 0.3 0.2 -0.9
Medication: Seretide 50 evohaler 3.7 4.2 10.2 2.8 1.3 -2.6 -1.4 -2.8 -3.2 -2.8 -1.8 -1.0 1.6 -1.8 1.5 -0.4 -0.5 -2.5
Mean time to correctly identify matches 1.9 3.7 13.5 -0.4 -2.7 1.4 2.1 0.4 0.4 1.1 -1.4 -1.5 -1.9 -0.5 -2.1 -3.6 -3.7 0.6
Heart disease (mother) 0.8 1.0 4.0 -1.0 -1.7 0.8 1.6 0.1 0.2 0.6 -1.3 -0.4 -0.8 -0.3 -2.0 0.0 0.5 0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.8 2.1 12.5 -1.0 1.0 -0.1 0.3 0.3 0.4 -0.0 2.3 2.9 0.9 3.5 1.3 -0.5 -0.6 0.6
Whole body fat mass 0.4 1.9 5.1 -1.6 -0.5 1.6 -0.1 2.1 2.3 1.9 0.3 0.5 -0.2 1.4 -0.4 0.4 2.0 1.6
Leg fat mass (right) 0.5 1.9 5.2 -0.9 -0.6 1.3 -0.6 2.0 2.1 1.7 0.4 0.8 0.3 2.1 0.1 0.6 2.3 1.6
Arm predicted mass (right) 0.9 4.4 13.1 0.2 -2.5 2.7 1.0 3.1 3.6 3.1 1.0 -0.5 -1.6 1.5 -1.9 0.0 1.3 2.8
Pulse rate, automated reading 0.2 0.8 2.5 -0.2 1.2 -0.9 -0.9 -0.9 -1.0 -0.7 -1.6 -0.9 0.3 0.5 0.7 0.8 0.2 -1.0
Alcohol intake frequency. 0.5 1.1 2.3 -0.3 -0.9 1.5 1.4 0.7 1.0 1.5 -0.7 -0.8 -0.8 -0.3 -0.7 -1.5 -1.5 1.1
Comparative height size at age 10 0.2 1.0 3.7 0.5 -0.0 1.2 0.0 1.6 1.9 1.3 -0.0 -1.5 -0.1 -0.9 -0.1 0.4 1.1 1.0
Number of full sisters 0.5 0.6 2.0 0.1 -0.4 0.7 0.9 -0.3 -0.3 0.3 -0.8 -0.6 -1.4 -0.4 -1.0 -0.5 -0.9 1.1
Suffer from ‘nerves’ 0.8 1.3 5.1 0.4 -0.1 -1.2 -0.2 -1.1 -1.0 -1.1 0.3 -1.3 -1.1 -1.8 -0.5 -1.2 -2.3 -1.0
Overall health rating 0.5 1.0 3.0 -1.1 -0.6 -1.1 -0.9 -0.7 -1.2 -0.9 -1.0 -0.5 -0.5 -1.4 -0.4 -1.1 -1.7 -0.9
Chest pain or discomfort 1.3 1.9 4.4 1.5 2.0 -2.1 -1.4 -1.3 -1.9 -2.1 0.3 1.3 0.3 -0.5 1.4 0.4 -0.4 -1.1
Had major operations 0.6 0.7 2.6 0.9 0.5 0.2 0.8 0.0 0.0 0.0 -0.6 -1.0 -0.2 -1.2 -0.4 -1.5 -1.6 0.7
Age at last live birth 0.3 0.4 2.2 0.2 -1.5 -0.1 0.4 -0.7 -0.4 0.0 0.2 0.2 -0.8 -0.4 -0.9 -1.2 -0.5 0.1
Family relationship satisfaction 0.8 1.0 6.7 -2.6 -1.1 0.9 1.2 0.4 0.6 0.9 -0.8 0.1 -0.9 0.3 -1.3 0.3 -0.3 0.6
Leg pain on walking 2.3 2.9 8.8 0.0 2.4 -1.7 -3.0 -0.2 -0.5 -1.3 0.6 2.0 2.1 1.7 2.2 1.7 2.1 -0.2
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.5 2.7 -1.0 -0.4 0.6 0.5 0.2 -0.2 0.6 -0.7 -0.5 0.2 -1.1 -0.6 -1.6 -0.3 0.0
Commuting to job workplace: Car/motor vehicle 1.3 1.5 5.7 2.4 -0.1 -1.2 -1.1 -1.7 -1.7 -1.3 -0.9 -0.9 -0.2 -1.1 -0.1 1.3 0.9 -1.3
Illness, injury, bereavement, stress in last 2 years 1.7 2.1 5.8 -0.1 -1.3 2.2 0.8 1.9 2.4 2.3 1.7 -0.3 -0.9 0.7 -0.5 -0.7 0.2 1.9
Medication: Aspirin 1.9 2.4 4.7 0.5 1.9 -2.1 -1.9 -2.0 -1.8 -2.1 -1.0 1.3 1.4 -0.2 1.6 -0.5 -0.9 -2.2
Supplements: Vitamin C 0.9 1.0 3.2 1.6 -0.4 -0.8 0.0 -0.7 -0.9 -0.7 0.8 0.5 0.6 -1.3 0.4 1.8 1.6 -0.9
Knee pain experienced in last month 0.4 0.6 2.0 0.6 -1.0 -0.5 -1.4 -0.2 -0.2 -0.2 -0.9 -1.3 -0.6 -0.4 -0.4 0.0 1.4 -1.0
Hypertension (Self-reported) 0.2 0.6 1.8 -0.3 -0.4 1.1 0.4 1.0 1.3 1.4 -0.2 0.1 0.1 1.0 0.1 -0.6 0.6 1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.2 1.4 3.6 0.2 0.8 -1.7 -1.1 -1.8 -1.9 -1.7 -1.5 -0.1 0.6 -1.0 0.1 0.1 0.2 -1.8
Illnesses of father: Heart disease 2.3 3.1 8.8 -0.1 -2.1 1.7 2.6 0.4 1.1 1.5 -2.3 -2.0 -2.5 -1.0 -3.0 -1.1 -1.3 1.0
Illnesses of siblings: Diabetes 0.3 0.4 1.1 0.7 -0.3 0.5 0.8 0.5 0.8 0.4 0.7 0.5 0.1 -0.5 -0.3 -1.0 -0.7 0.8
Smoking status: Previous 0.4 0.7 1.8 0.7 -1.3 -0.5 0.0 -0.8 -0.6 -0.5 -0.7 -0.5 -1.1 0.6 -0.8 -1.1 -1.4 -0.6
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 1.8 -0.8 0.7 1.0 1.3 0.7 0.4 0.7 1.2 0.4 0.5 -0.6 0.0 0.5 0.3 0.9
Whole body fat-free mass 1.0 5.9 17.4 -0.2 -2.5 3.3 1.5 3.7 4.2 3.6 1.4 -0.5 -1.9 1.6 -2.0 0.3 1.4 3.3
Leg fat-free mass (right) 0.8 4.1 11.8 -0.9 -1.6 2.8 1.2 3.2 3.4 3.0 1.3 -0.0 -1.4 1.1 -1.3 0.3 1.5 2.8
Arm fat percentage (left) 0.4 1.5 6.6 -2.6 -0.3 1.4 0.2 1.5 1.6 1.6 -0.1 0.8 0.0 1.3 0.0 0.2 1.7 1.3
Average weekly red wine intake 2.6 3.9 7.9 0.4 -2.6 2.8 2.6 1.9 2.4 2.8 -1.1 -0.9 -1.9 -0.6 -2.1 -2.1 -1.3 1.8
Handedness (chirality/laterality): Left-handed 0.5 0.6 2.1 -1.4 0.1 -0.7 0.4 -1.0 -1.0 -0.9 -0.6 0.7 0.7 0.1 0.4 0.3 0.6 -1.2
Mood swings 0.7 1.3 5.9 2.4 -0.5 1.2 -0.3 1.5 1.5 1.4 0.8 -0.9 0.8 0.6 0.4 -0.2 0.9 1.6
Loneliness, isolation 0.4 0.5 1.2 -0.2 0.9 1.0 0.3 1.1 1.1 1.1 -0.1 -0.6 0.1 -0.2 0.9 -0.6 0.1 0.8
Long-standing illness, disability or infirmity 0.4 0.6 2.4 0.4 -0.1 0.2 -0.4 0.6 0.5 0.4 -0.6 -1.1 -0.0 -1.0 0.2 -1.6 -1.4 0.5
Ever had bowel cancer screening 1.0 1.2 3.2 -1.4 0.8 -1.3 -1.7 -1.1 -0.8 -0.9 -0.7 1.8 0.6 0.9 0.8 0.6 1.1 -0.9
Diabetes diagnosed by doctor 0.1 0.2 0.6 0.4 0.4 0.3 -0.4 0.6 0.8 0.5 -0.2 -0.5 0.2 0.0 0.6 0.6 0.8 0.1
Ever had stillbirth, spontaneous miscarriage or termination 0.7 0.7 2.6 -0.6 0.6 -0.1 -0.4 -0.2 0.1 0.2 -1.1 1.1 1.6 1.1 1.4 -1.0 0.4 0.4
Friendships satisfaction 1.8 2.2 4.8 -1.7 -0.9 1.6 0.3 2.0 2.0 1.9 1.5 -0.3 -2.2 -0.2 -1.8 -0.1 -1.0 2.1
Qualifications: nursing, teaching 0.3 0.4 1.4 0.2 0.7 -0.2 0.9 -1.2 -0.7 -0.5 -0.6 -0.3 0.3 -0.7 0.5 -0.9 -0.5 -0.3
Commuting to job workplace: Walk 1.1 1.2 2.9 -0.5 -1.1 0.9 1.1 1.2 1.2 0.9 1.7 0.9 -0.3 1.6 -0.8 -1.2 -1.4 0.7
Eye problems/disorders: Cataract 1.1 1.3 4.1 0.2 -1.0 1.8 2.0 1.2 1.2 1.7 -0.3 -1.0 -0.5 0.1 -0.8 -0.4 0.3 1.7
Mouth/teeth dental problems: Mouth ulcers 0.5 0.7 4.0 0.9 -0.5 0.2 1.1 -0.6 -0.1 0.1 -2.0 -1.1 -0.8 -0.3 -1.2 -0.8 -0.5 -0.3
Medication for cholesterol 1.0 1.4 3.2 0.4 -1.5 1.4 1.2 1.5 1.3 1.1 1.8 -0.4 -1.6 0.7 -1.8 -0.1 -0.7 0.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.3 1.5 4.8 0.2 0.2 -1.6 -2.2 -1.2 -1.1 -1.3 -1.1 1.1 -1.6 -0.3 -1.1 1.6 0.6 -1.0
Back pain experienced in last month 0.7 1.0 2.7 -0.1 0.4 0.5 -0.8 1.5 1.6 1.0 1.3 1.1 0.5 1.6 0.8 0.7 0.8 0.6
Mineral and other dietary supplements 1.1 1.5 3.4 -1.4 -0.8 1.1 0.2 1.4 1.4 1.3 0.7 -0.3 -1.1 0.1 -1.2 -1.8 -1.9 1.7
Breast cancer (self-reported) 1.7 2.0 6.0 1.9 -1.6 0.3 0.6 -0.6 -0.3 0.0 -2.2 -2.1 -2.1 -1.6 -2.5 0.5 0.3 -0.6
Asthma (self-reported) 0.6 1.2 5.1 1.5 -0.6 0.3 1.3 0.3 0.1 0.2 0.8 -1.9 -0.8 -2.3 -0.5 -1.3 -1.1 0.4
Osteoporosis (self-reported) 1.6 2.0 5.7 1.4 0.9 -1.6 -2.4 -1.0 -1.2 -1.4 -0.8 1.8 1.6 0.8 1.7 1.2 1.3 -1.2
Osteoarthritis (self-reported) 0.5 0.7 2.2 -0.5 0.7 -1.1 -1.5 -1.0 -0.2 -0.7 -0.8 0.2 -0.2 -0.4 0.3 1.4 1.2 -0.4
Medication: Aspirin 1.9 2.4 6.1 0.5 1.8 -2.1 -2.5 -1.9 -1.7 -2.0 -1.0 1.5 1.3 -0.1 1.5 -0.3 -0.7 -1.9
Medication: Gliclazide 0.3 0.4 2.8 -0.9 0.6 0.5 0.3 0.3 0.1 0.4 -1.7 -0.2 0.1 0.4 0.5 0.3 0.6 -0.1
Illnesses of father: None of the above (group 1) 1.0 1.2 3.6 0.3 0.8 -1.5 -1.9 -0.3 -0.8 -1.4 1.6 0.9 1.3 0.5 1.3 1.2 0.3 -0.7
Smoking status: Current 0.6 0.9 2.3 -1.3 1.1 -1.1 -1.5 -0.6 -1.3 -1.0 0.8 0.1 0.8 0.3 0.9 0.8 0.2 -1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.8 1.7 9.9 1.3 0.1 0.3 -1.3 1.2 1.1 0.6 2.3 1.4 0.3 3.1 0.5 0.1 0.3 0.9
Whole body water mass 1.0 5.8 16.9 -0.2 -2.4 3.2 1.4 3.7 4.1 3.6 1.3 -0.5 -1.9 1.6 -1.9 0.3 1.5 3.3
Leg predicted mass (right) 0.8 4.0 11.9 -0.9 -1.5 2.8 1.1 3.2 3.5 3.0 1.4 0.0 -1.4 1.1 -1.3 0.4 1.5 2.8
Arm fat mass (left) 0.6 2.6 6.5 -2.2 -1.1 2.0 0.4 2.3 2.5 2.3 0.1 0.5 -0.6 1.7 -0.7 0.4 2.0 1.9
Number of self-reported non-cancer illnesses 0.4 0.7 5.2 0.3 -0.7 -0.3 -0.2 -0.7 -0.4 -0.3 -1.1 -0.7 -0.0 -0.7 -0.3 -2.3 -1.3 -0.3
Average weekly champagne plus white wine intake 0.5 0.7 5.0 -0.5 0.0 -0.6 -1.0 -0.5 -0.6 -0.5 1.4 2.2 -0.1 -0.0 -0.2 0.5 0.8 0.2
Miserableness 0.4 0.7 3.6 1.1 0.1 0.6 -0.4 1.2 1.1 0.8 1.9 0.2 0.1 0.4 0.3 0.1 0.8 0.9
Guilty feelings 3.2 4.7 9.1 -1.1 -2.4 3.0 2.2 2.7 3.0 3.0 -0.2 -2.1 -1.8 -1.6 -1.9 -2.2 -1.4 2.3
Wears glasses or contact lenses 0.5 0.6 1.9 1.4 -0.5 -0.6 -0.3 -0.8 -0.5 -0.6 -0.9 -1.3 -0.9 0.0 -0.8 0.4 -0.0 -0.8
Ever taken oral contraceptive pill 0.5 0.5 2.4 1.0 -0.7 -0.2 -0.9 0.8 0.6 0.0 1.6 1.1 0.1 -0.6 0.2 0.1 -0.0 0.6
Hearing aid user 0.8 0.9 2.3 -1.1 1.3 -0.1 -1.1 1.0 0.8 0.3 1.5 0.4 1.2 0.5 1.4 1.0 0.7 0.7
Mother’s age at death 0.2 0.3 1.1 0.1 -0.5 -0.0 0.8 -0.5 -0.2 -0.0 -0.8 0.2 0.0 -1.1 -0.6 0.1 0.3 -0.8
Financial situation satisfaction 0.8 1.0 2.9 -1.1 1.6 -0.8 -1.3 0.0 -0.5 -0.7 0.9 0.7 0.9 -1.7 1.5 -0.1 -1.0 -0.3
Tinnitus: Yes, now most or all of the time 3.8 4.4 9.0 -1.3 2.6 -2.8 -2.3 -2.1 -2.4 -3.0 -1.1 1.9 2.0 0.1 2.0 1.9 1.8 -2.4
Commuting to job workplace: Public transport 2.4 2.9 6.3 -0.8 -1.0 2.2 1.8 2.1 2.4 2.4 1.4 0.6 -0.6 1.1 -0.5 -2.5 -1.8 2.0
Eye problems/disorders: Glaucoma 0.6 0.8 3.9 1.1 -0.4 -0.2 -1.2 0.8 0.5 0.0 2.0 1.0 1.0 0.5 0.6 0.7 0.8 -0.3
Medication: Blood pressure 0.1 0.3 1.3 -0.1 -0.1 -0.1 -0.5 -0.1 0.2 0.3 -1.1 0.4 0.6 -0.3 0.5 0.5 1.2 -0.0
Pain type(s) experienced in last month: Hip pain 0.5 0.6 4.1 -0.5 -0.8 -0.0 0.5 0.2 0.5 0.1 0.9 -0.0 -0.6 -0.2 -0.1 -1.5 -2.0 -0.8
Supplements: Fish oil (including cod liver oil) 0.9 1.2 5.9 2.4 0.5 -1.0 -0.5 -1.0 -1.0 -1.2 -0.2 0.6 0.5 0.6 0.8 1.7 1.2 -1.2
High cholesterol (Self-reported) 1.4 2.5 8.0 1.0 0.1 -2.3 -0.7 -2.8 -2.2 -2.3 -2.2 1.1 0.3 1.2 0.4 -0.6 -1.3 -1.9
Medication: Bendroflumethiazide 0.2 0.3 1.0 -0.6 0.4 0.2 -0.9 0.9 0.7 0.6 -0.1 0.3 -0.3 1.0 0.4 -0.6 -0.4 0.7
Medication: Paracetamol 0.4 0.6 2.6 0.4 -0.6 -0.0 -0.6 -0.3 -0.1 0.1 -1.6 -0.4 -1.5 -0.5 -1.4 0.1 0.6 -0.6
Medication: Lisinopril 0.3 0.4 2.0 -0.0 1.1 -0.1 -0.3 0.4 0.6 0.3 -0.5 0.2 0.5 0.8 0.6 1.0 1.4 0.3
Medication: Atorvastatin 0.6 0.8 2.6 -1.6 -1.0 -0.1 -0.1 0.2 0.4 -0.1 0.6 0.6 -1.6 -0.8 -1.2 0.0 -1.6 -0.1
Illnesses of father: High blood pressure 1.3 1.6 5.1 -0.3 -1.1 1.2 1.9 -0.2 0.7 1.2 -2.3 -1.5 -1.4 -0.1 -1.6 -1.9 -0.4 0.7
Alcohol drinker status: Never 1.8 2.2 8.1 -1.5 -2.9 1.0 1.8 -0.3 -0.1 0.7 -1.0 -0.6 -1.5 0.0 -2.0 -2.2 -2.1 -0.2
Ever smoked 0.3 0.5 1.9 -0.3 -1.2 -0.1 -0.3 -0.2 -0.0 0.1 -0.7 -1.1 -0.9 0.5 -0.7 -0.9 -1.4 -0.3
Basal metabolic rate 1.0 5.6 16.2 -0.5 -2.3 3.2 1.4 3.6 4.0 3.6 1.2 -0.5 -1.7 1.5 -1.8 0.3 1.7 3.2
Leg fat percentage (left) 0.3 1.2 5.0 -0.5 -0.1 0.6 -1.1 1.3 1.3 1.0 -0.3 0.7 0.9 2.1 0.8 0.2 2.2 0.6
Arm fat-free mass (left) 1.3 6.6 20.1 0.1 -2.9 3.4 1.4 4.0 4.5 3.9 1.0 -0.6 -1.7 1.7 -2.1 -0.0 1.7 3.4
Number of operations (self-reported) 0.6 0.9 4.5 1.6 0.7 -0.2 -0.2 -0.3 -0.2 -0.1 -2.1 -0.6 -0.7 -0.2 -0.6 -1.7 -1.0 0.2
Average weekly beer plus cider intake 5.2 7.5 19.3 -0.0 3.7 -3.7 -4.4 -2.0 -3.0 -3.4 0.2 2.3 1.9 2.0 3.5 2.4 1.4 -3.0
Irritability 0.9 1.6 5.3 -0.8 -1.7 -0.7 -0.2 -0.9 -1.0 -0.8 -0.0 -0.3 -2.3 1.5 -2.0 -0.6 -2.0 -1.1
Risk taking 2.4 3.5 8.0 0.7 0.7 1.7 -0.4 2.7 2.3 1.8 2.6 1.7 0.8 1.8 1.0 2.0 2.8 2.5
Ever had prostate specific antigen (PSA) test 0.6 0.7 2.7 1.6 -0.2 0.4 0.1 0.5 1.1 0.6 0.9 0.9 0.8 1.6 0.4 0.3 1.0 -0.0
Fractured/broken bones in last 5 years 0.2 0.3 1.0 -0.0 0.4 -0.1 -1.0 0.8 0.4 0.1 0.8 0.6 0.2 0.8 0.3 0.1 0.1 0.2
Age started oral contraceptive pill 0.5 0.6 1.7 0.3 -1.3 0.6 -0.5 0.8 1.3 0.8 0.3 0.6 -0.3 -0.2 -0.4 1.0 1.2 0.4
Diastolic blood pressure, automated reading 0.2 0.5 2.9 -1.2 1.7 -0.1 -0.7 -0.2 -0.5 -0.1 -0.6 -0.1 0.6 -0.0 1.0 -0.9 -0.7 0.1
Ever depressed for a whole week 4.0 4.9 12.0 0.6 1.4 -3.2 -1.8 -3.2 -3.2 -3.0 -1.3 1.3 2.2 0.0 2.0 -1.1 -1.4 -3.5
Unable to work because of sickness or disability 1.2 1.6 5.2 2.1 0.8 -1.7 -2.3 -0.6 -1.2 -1.6 -0.4 -1.1 0.9 -0.1 1.1 1.3 0.3 -1.0
Commuting to job workplace: Cycle 0.7 0.9 3.0 0.7 -1.4 0.4 -0.5 0.7 0.6 0.7 -0.8 -1.7 -1.1 -0.8 -1.0 -1.0 -0.9 1.0
Myopia 1.2 1.8 6.9 -2.1 -0.4 0.3 2.4 -1.0 -0.5 -0.0 -1.0 -0.9 -1.6 -2.6 -1.5 0.9 -1.0 0.2
Vascular/heart problems diagnosed by doctor 0.1 0.3 0.9 -0.2 -0.0 -0.6 -0.4 -0.4 -0.9 -0.9 0.9 0.9 0.3 0.3 0.1 0.3 -0.1 -0.6
Cholesterol lowering medication 1.7 2.5 6.6 1.2 -0.4 -2.2 -1.2 -2.6 -2.1 -2.1 -2.5 -0.9 -0.2 -1.3 -0.2 -0.1 -0.8 -2.0
Medication: Omeprazole (e.g. Zanprol) 0.6 0.8 1.8 0.9 0.8 -1.3 -1.4 -0.5 -0.8 -1.0 -0.9 0.1 1.0 -0.3 1.1 -0.3 -0.3 -1.1
Pain experienced in last month 0.3 0.5 4.1 -0.0 -0.0 0.9 2.0 -0.4 0.0 0.5 -0.5 -0.4 0.1 -0.4 -0.4 -0.2 -1.1 0.3
Supplements: Calcium 0.7 0.8 2.1 0.1 0.9 -0.7 -1.1 -0.9 -1.1 -0.8 -1.1 -0.1 0.8 -0.7 0.7 1.5 0.9 -0.7
Basal cell carcinoma (self-reported) 1.4 1.6 7.5 1.0 1.0 -0.8 -1.3 -0.8 -0.9 -0.9 0.9 1.9 2.7 0.4 2.2 -0.6 0.3 -0.5
Heart attack/myocardial infarction (self-reported) 0.7 0.9 5.0 2.2 -0.6 0.8 0.5 1.0 0.9 0.9 0.2 -0.8 -1.1 0.1 -0.8 -0.6 -1.1 0.9
Deep venous thrombosis (DVT) (self-reported) 1.3 1.6 4.0 0.0 1.2 -2.0 -1.0 -1.3 -1.6 -2.0 0.1 1.6 1.2 0.6 1.5 -0.4 -0.6 -1.6
Heart disease (siblings) 0.7 0.8 4.1 -1.2 0.5 -0.2 -0.8 0.3 0.3 -0.2 0.9 1.1 1.0 2.0 1.3 0.0 1.1 0.1
Alcohol drinker status: Previous 0.5 0.6 2.0 -1.4 -0.1 -1.1 -0.6 -0.8 -0.9 -1.1 0.1 0.2 0.1 -0.0 0.8 -0.1 -1.2 -0.6
Pack years of smoking 0.7 1.0 2.8 -1.2 -0.5 1.3 1.7 1.5 1.0 1.1 1.2 -0.7 0.2 -0.7 -0.3 -0.3 -1.0 0.6
Impedance of whole body 0.9 4.6 11.6 0.0 2.8 -2.5 -1.0 -2.9 -3.4 -2.9 -1.3 -0.2 2.3 -2.8 1.8 -0.3 -0.9 -2.7
Leg fat mass (left) 0.5 2.0 5.2 -0.9 -0.6 1.5 -0.5 2.2 2.3 1.8 0.3 0.6 0.1 2.2 -0.0 0.4 2.1 1.6
Arm predicted mass (left) 1.2 6.1 18.3 0.4 -2.6 3.3 1.3 3.9 4.3 3.7 1.1 -0.7 -1.6 1.7 -1.9 0.1 1.7 3.3