Hub : Genes

PRKCB

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2440	0.0370	7.8e-16	0.170	0.159	0.191	0.183	0.182	3.7e-20	6.0e-19	8.8e-23	8.8e-22	1.3e-21
2	GTEx	Adrenal Gland	0.2679	0.0991	2.5e-03	0.113	NA	0.004	NA	0.030	7.3e-05	NA	2.3e-01	NA	3.0e-02
3	GTEx	Artery Aorta	0.1640	0.0530	5.1e-04	0.128	NA	0.066	NA	0.099	1.6e-07	NA	1.7e-04	NA	4.0e-06
4	GTEx	Artery Tibial	0.2550	0.0447	1.2e-13	0.249	NA	0.245	NA	0.262	1.8e-19	NA	3.3e-19	NA	1.3e-20
5	GTEx	Colon Sigmoid	0.3250	0.0900	2.4e-03	0.131	NA	0.063	NA	0.100	2.4e-05	NA	2.9e-03	NA	2.2e-04
6	GTEx	Colon Transverse	0.1550	0.0590	4.4e-03	0.083	NA	0.039	NA	0.065	8.9e-05	NA	5.7e-03	NA	5.0e-04
7	GTEx	Esophagus Muscularis	0.2920	0.0560	3.4e-09	0.263	NA	0.227	NA	0.254	3.7e-16	NA	6.1e-14	NA	1.4e-15
8	GTEx	Testis	0.2110	0.0830	7.8e-03	0.000	NA	0.014	NA	0.005	3.3e-01	NA	7.3e-02	NA	1.8e-01
9	METSIM	Adipose	0.0835	0.0272	2.2e-04	0.000	0.025	0.022	0.006	0.010	3.2e-01	8.7e-05	2.7e-04	3.3e-02	1.1e-02
10	NTR	Blood	0.1257	0.0220	0.0e+00	0.039	0.080	0.092	0.094	0.103	1.2e-12	1.2e-24	3.9e-28	1.1e-28	2.5e-31
11	ROSMAP	Brain Pre-frontal Cortex	0.1069	0.0391	5.9e-03	0.002	0.013	-0.002	0.015	-0.002	1.9e-01	7.2e-03	6.2e-01	3.7e-03	8.0e-01
12	YFS	Blood	0.2643	0.0312	0.0e+00	0.194	0.222	0.240	0.231	0.238	2.6e-61	4.4e-71	2.9e-77	3.0e-74	9.7e-77
13	TCGA	Breast Invasive Carcinoma	0.0839	0.0251	2.3e-06	0.010	0.032	0.032	NA	0.040	3.7e-03	2.8e-07	3.3e-07	NA	9.5e-09
14	TCGA	Kidney Renal Clear Cell Carcinoma	0.1316	0.0439	8.8e-04	0.004	0.051	0.061	NA	0.037	9.3e-02	2.1e-06	1.9e-07	NA	4.3e-05
15	TCGA	Prostate Adenocarcinoma	0.0963	0.0374	8.3e-05	0.068	0.032	0.064	NA	0.063	1.2e-07	2.4e-04	3.2e-07	NA	3.7e-07

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Bipolar Disorder (2018)	2.2	3.5	7.8	-0.7	1.5	-1.8	-2.8	-0.9	-0.8	-1.3	2.3	2.5	1.7	1.8	2.1	2.4	2.3	-1.3
Bipolar Disorder or Schizophrenia	1.0	2.3	5.6	-0.4	0.8	-2.3	-2.4	-1.4	-1.3	-1.9	0.9	0.5	1.3	1.6	1.5	2.3	1.0	-1.6
Depressed Affect (Nagel 2018)	0.4	0.8	1.7	1.2	0.3	1.1	-0.3	0.9	1.1	1.3	-0.6	-1.2	0.6	0.5	0.4	-0.3	1.1	0.9
Depression (Nagel 2018)	0.5	0.7	4.2	-0.3	0.2	-0.0	0.2	-1.1	-0.7	-0.3	-1.4	-1.3	0.2	-2.1	0.0	-0.0	0.5	-0.6
Intelligence (Savage-Jansen 2018)	0.6	1.9	21.9	-4.7	-0.2	-0.3	0.0	-0.5	-0.3	-0.4	1.0	1.8	-0.5	-0.3	-0.7	-0.7	-0.6	-0.3
Neuroticism (Nagel 2018)	0.2	0.5	1.7	-0.2	-0.9	0.8	-0.2	0.6	0.7	0.9	-0.5	-1.3	-0.7	0.4	-0.5	-0.8	0.1	0.5
Schizophrenia (2018)	0.4	0.8	2.2	0.1	-0.2	-1.5	-0.8	-1.1	-1.1	-1.3	-0.7	-1.4	0.4	0.3	0.3	0.9	-0.3	-1.1
Schizophrenia vs Biploar Disorder	1.7	2.2	8.1	-0.6	-0.3	1.4	2.6	0.4	0.8	1.0	-2.3	-2.8	0.4	-1.6	0.2	-1.8	-1.6	0.3
Worry (Nagel 2018)	0.6	1.3	2.5	-0.6	-0.7	-1.2	-0.6	-1.5	-1.6	-1.1	-1.3	-1.6	-0.8	-1.5	-0.8	-0.6	-0.9	-1.2
Alzheimer’s Disease (in mother)	1.1	1.3	4.8	1.9	-0.7	-0.9	-1.6	-0.3	-0.5	-0.7	1.2	0.9	-0.0	2.2	0.2	-1.0	-1.8	-0.3
Alzheimer’s Disease (in father)	0.5	0.6	1.7	0.1	0.3	1.0	0.4	1.1	1.2	1.1	-0.9	-0.4	-0.7	0.5	-0.0	-0.2	-0.0	1.3
Alzheimer’s Disease (including proxy)	0.9	1.2	5.3	1.7	0.0	-0.2	-1.8	1.0	0.8	0.2	1.4	0.6	-0.5	2.3	0.4	-0.6	-1.2	0.8
Crohns Disease (2017)	1.3	2.9	9.4	-1.1	3.1	-2.2	-2.1	-2.0	-1.6	-1.9	-1.1	0.3	1.8	-0.2	2.2	1.1	0.7	-1.5
Irritable Bowel Disease (IBD)	4.9	11.8	25.6	-1.4	5.1	-5.0	-3.5	-4.5	-4.3	-4.8	-2.2	1.5	3.2	0.8	3.9	1.5	0.3	-3.9
Ulcerative Colitis (UC)	7.1	13.3	30.1	-1.2	5.3	-5.5	-3.0	-4.8	-4.7	-5.4	-2.2	1.9	3.2	1.1	3.9	1.5	-0.2	-4.3
Major Depression (MDD)	2.2	2.6	6.0	-0.4	1.1	-2.0	-2.5	-1.8	-2.2	-1.7	-1.2	1.5	1.7	0.3	1.4	1.1	1.2	-2.2
Reaction Time	1.9	3.7	15.1	0.2	-2.3	0.7	2.2	-0.6	-0.5	0.3	-2.2	-1.8	-1.8	-1.2	-2.0	-3.4	-3.9	-0.3
Verbal and Numeric Reasoning (VNR)	0.3	0.7	4.9	-2.2	-0.5	-0.2	0.5	-0.6	-0.5	-0.4	0.4	0.3	-1.1	-0.3	-1.2	-0.3	-0.5	-0.6
Breast Cancer	0.1	0.2	0.7	-0.7	0.4	0.2	-0.2	0.7	0.7	0.5	0.2	0.0	-0.6	-0.5	-0.2	0.1	0.3	0.9
Ovarian Cancer	3.4	4.6	10.2	0.5	2.4	-3.0	-2.3	-2.5	-3.2	-3.2	-0.4	2.1	1.9	0.4	2.2	1.4	0.9	-2.5
Prostate Cancer	0.9	1.3	3.5	-0.5	0.7	-1.4	-1.3	-1.2	-1.4	-1.3	-0.0	1.9	1.3	0.0	1.0	-0.7	-0.2	-1.8
Age at First Birth	2.7	4.0	12.7	-2.2	-2.8	1.5	3.6	-0.4	-0.1	0.9	-2.1	-2.2	-2.7	-1.6	-3.2	-0.6	-0.8	0.1
Bipolar Disorder (2011)	1.5	1.5	5.0	0.6	0.3	-2.0	-2.2	-1.7	-1.2	-1.7	-0.1	1.9	0.4	1.2	0.8	0.3	0.2	0.0
Body Mass Index (BMI) (2010)	0.7	1.0	2.6	0.5	-1.0	1.5	0.7	1.4	1.5	1.6	0.2	0.6	0.3	1.4	-0.3	-0.7	-0.1	1.0
Coronary Artery Disease (CAD)	0.9	1.0	3.8	-0.5	-0.8	1.5	1.9	0.9	1.3	1.2	0.3	-0.5	-0.3	-1.2	-1.2	0.0	-0.1	1.0
Crohns Disease (2012)	1.7	2.8	6.7	-1.1	2.6	-2.0	-2.2	-1.5	-1.0	-1.7	-0.2	0.6	2.3	-0.6	2.6	1.8	1.0	-1.2
Mean Putamen Volume	0.5	0.6	4.0	0.2	0.2	0.7	0.5	0.3	0.4	0.7	0.0	-0.3	-0.4	-0.7	-0.8	-2.0	-1.2	0.4
Fasting Glucose	0.9	1.1	10.6	0.8	-0.6	-0.1	0.4	-0.0	0.8	0.5	0.1	0.7	0.3	0.8	0.3	-3.2	-1.6	0.0
HbA1C	0.6	0.6	3.1	-0.8	0.9	0.1	-0.0	0.6	0.3	0.1	0.9	0.7	0.0	-0.4	0.4	-1.8	-1.8	-0.2
HDL Cholesterol	0.1	0.2	0.8	-0.7	0.9	0.1	0.5	0.0	0.2	0.1	-0.1	0.0	0.0	0.0	0.6	-0.3	-0.7	0.1
LDL Cholesterol	0.5	0.9	1.8	-0.9	1.1	-1.1	-0.4	-1.3	-1.1	-1.1	-0.3	0.4	1.1	0.8	1.1	0.3	-0.0	-1.3
Lupus	0.5	0.8	2.3	-0.7	-1.2	0.4	-0.5	0.4	0.4	0.7	-0.4	-0.5	-1.4	-1.5	-1.3	-0.0	-0.9	1.0
Neuroticism (2016)	0.5	0.8	2.6	0.2	0.1	0.2	-0.9	1.0	1.1	0.6	1.6	1.2	1.0	0.9	0.8	-0.8	-0.7	0.5
Primary Biliary Cirrhosis	0.6	0.9	3.8	0.3	-1.0	-0.4	-0.4	-0.4	-0.4	-0.3	-0.5	0.6	1.2	1.1	-0.2	1.5	2.0	-1.4
Rheumatoid Arthritis	0.6	0.8	4.2	-0.5	-2.0	0.4	0.3	0.3	-0.1	0.4	1.0	0.2	-0.5	-0.9	-1.1	-0.9	-1.3	0.9
Schizophrenia (2014)	0.7	1.5	3.4	-0.5	0.5	-1.8	-1.7	-1.2	-0.9	-1.5	-0.3	-0.2	1.4	1.6	1.5	1.8	0.6	-1.2
Triglycerides	0.2	0.4	1.7	0.8	-0.2	0.6	0.3	0.4	0.4	0.3	-0.4	-1.3	-0.6	-0.3	-0.7	-0.7	-0.6	0.7
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.1	0.8	1.5	-0.8	0.1	-0.8	-0.5	-0.8	-0.8	0.3	1.1	-0.0	0.8	-0.9	-1.2	-0.2
Ulcerative Colitis	6.0	8.6	17.7	-1.2	4.0	-4.1	-2.1	-3.8	-3.7	-4.2	-2.2	1.3	3.3	0.8	3.6	0.9	0.2	-3.7
Blood Eosinophil Count	0.4	3.2	15.8	-0.4	-0.6	1.3	2.0	0.0	0.2	0.8	-2.0	-3.1	-0.9	-2.5	0.2	-4.0	-2.1	0.7
Blood Platelet Count	0.1	1.0	3.4	0.2	1.4	-0.9	-1.6	0.2	0.4	-0.5	1.9	0.8	0.4	-0.6	0.9	1.5	0.9	-0.4
Blood Red Count	0.1	0.9	2.2	0.6	0.1	1.1	0.2	1.5	1.2	1.4	0.2	0.1	1.1	1.3	1.1	-0.5	0.1	1.1
Blood White Count	0.6	4.3	16.8	1.2	-2.0	2.0	1.9	1.2	1.6	1.8	0.1	-2.4	-4.1	-1.5	-2.2	-2.2	-2.5	1.9
Heel T-Score	0.2	1.3	10.3	-0.1	1.0	-0.8	-1.4	0.2	0.0	-0.5	3.2	1.1	0.4	1.2	1.2	0.9	0.4	-0.4
BMI	1.0	6.0	16.2	-1.7	-1.5	3.4	1.0	3.8	4.0	3.8	0.3	0.3	-0.7	3.0	-0.7	0.3	2.4	3.3
Height	0.1	1.0	4.5	0.3	0.2	0.4	-0.3	1.2	1.3	0.5	0.6	-1.5	-0.3	-2.1	-0.5	1.3	1.5	0.1
Waist Hip Ratio (WHR)	0.1	0.6	1.5	-0.1	0.3	-0.9	-0.8	-0.6	-0.7	-0.9	0.8	0.2	0.7	-0.1	0.6	1.2	1.2	-1.1
Systolic Blood Pressure	0.4	2.2	8.3	1.0	2.9	-1.6	-1.7	-0.9	-1.2	-1.4	2.2	1.2	1.6	0.5	2.2	0.0	-0.7	0.2
Smoking Status	0.3	0.7	1.8	0.3	0.6	-1.2	-1.0	-0.9	-1.3	-1.2	-0.5	-0.5	-0.1	0.3	0.5	-0.5	-1.0	-1.2
Allergy or Eczema	2.5	6.5	15.3	-0.5	-2.0	1.9	3.2	-0.5	-0.0	1.2	-3.3	-3.9	-3.1	-3.7	-2.4	-3.9	-2.8	0.2
Cardiovascular Disease	0.1	0.5	1.8	0.7	1.1	-0.0	0.1	-0.2	0.2	0.3	-0.3	1.0	1.2	0.8	1.3	-0.6	0.0	0.4
Hypothyroidism (self reported)	1.6	3.7	9.9	-0.0	-2.9	1.6	2.0	1.2	1.3	1.6	1.9	-2.3	-2.8	-2.1	-3.2	-0.6	-1.0	1.2
Respiratory disease	0.3	0.8	5.0	0.5	0.2	0.0	0.6	0.1	-0.1	-0.2	1.3	-0.7	-0.7	-0.8	-0.2	-2.2	-1.6	-0.1
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.5	0.5	1.0	0.6	-0.1	0.5	0.7	0.6	-1.2	-0.1	0.5	0.6	1.2	-0.6	0.5	0.5
Lung FEV1/FVC ratio	0.3	1.3	6.4	1.7	-0.6	0.1	-1.0	0.2	0.7	0.5	0.1	2.1	0.3	2.5	0.1	0.3	1.8	0.6
Lung FVC	0.1	0.3	2.1	0.3	0.6	0.4	-0.5	-0.1	0.2	0.4	-0.7	0.4	0.7	1.4	0.6	-0.3	0.1	0.0
Neuroticism	0.5	1.3	5.5	-0.3	-1.6	1.1	0.6	0.4	0.9	1.2	-1.8	-2.3	-1.2	-0.2	-1.0	-1.1	-0.4	0.4
Chronotype (morning person)	0.2	0.6	2.2	-1.5	0.6	0.7	0.9	0.3	0.4	0.5	-0.4	-1.0	-0.2	-1.4	-0.1	0.1	-0.7	0.8
Hair Pigment	0.1	1.8	4.2	1.4	-0.6	1.9	1.4	2.0	2.0	1.8	1.4	-0.2	-0.1	0.1	-0.6	0.6	1.3	1.8
Tanning	0.1	1.2	3.2	1.8	1.1	-1.4	-1.3	-0.8	-1.3	-1.4	-0.1	0.7	1.3	-0.5	1.1	0.2	0.3	-1.1
Hand grip strength (left)	0.4	1.0	6.3	2.5	-0.6	0.3	0.2	0.5	0.4	0.3	1.3	-1.1	-0.1	0.8	-0.1	0.9	1.7	0.4
Number of treatments/medications taken	0.5	0.9	2.2	0.8	0.2	-1.5	-1.4	-1.2	-1.2	-1.3	-0.6	1.1	0.2	0.2	0.1	-0.3	-0.2	-1.4
Average weekly spirits intake	1.3	1.6	6.5	0.5	1.8	-1.8	-2.6	-1.2	-1.3	-1.4	-0.5	1.5	-0.0	1.0	0.5	1.1	0.3	-1.0
Sensitivity / hurt feelings	0.7	1.2	4.3	0.5	0.2	1.0	-1.1	1.8	1.7	1.4	0.1	0.6	0.6	2.1	0.8	-0.3	0.7	1.0
Frequency of depressed mood in last 2 weeks	0.5	0.6	5.2	0.6	-0.0	0.3	0.6	-0.1	0.3	0.1	-0.2	-1.5	-0.8	-2.3	-0.2	0.8	0.2	-0.0
Hearing difficulty/problems: Yes	0.6	0.9	4.0	-2.0	0.1	0.3	0.3	0.9	0.8	0.5	1.8	0.9	-0.2	-0.6	-0.1	-1.1	-1.4	-0.1
Relative age of first facial hair	1.0	2.1	6.9	1.9	2.6	-1.7	-1.5	-1.1	-1.6	-1.8	1.3	0.0	1.4	0.4	1.5	-0.7	-1.2	-1.2
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.5	0.6	1.3	-1.2	-1.6	-0.6	-0.7	-1.0	-0.3	0.1	1.4	-0.2	1.5	0.6	0.1	-0.6
Ever used hormone-replacement therapy (HRT)	0.3	0.4	2.1	-1.4	-0.7	-0.3	-1.4	0.3	0.4	-0.0	0.6	0.5	0.5	0.1	0.2	-0.2	0.2	-0.6
Ever had hysterectomy (womb removed)	0.9	1.1	4.3	0.3	-0.3	1.1	0.4	1.4	2.1	1.5	0.6	0.7	1.3	1.2	0.7	-0.1	0.6	1.0
Systolic blood pressure, automated reading	0.4	1.2	4.5	0.7	1.5	-1.2	-2.1	-0.7	-1.0	-0.9	1.4	0.5	1.2	1.4	1.3	-0.2	-0.2	-0.3
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.7	0.6	-0.7	-0.3	0.1	-0.7	-0.7	-0.4	-0.6	-0.4	0.2	-1.3	-0.1	-0.0	0.6	-1.1
Angina	1.3	1.7	5.1	0.8	-0.3	-1.2	0.3	-1.4	-1.0	-1.4	-1.4	-1.5	-2.3	-1.3	-1.6	-0.4	-1.7	-1.2
Medication for hormone replacement therapy	0.4	0.5	1.8	0.2	0.5	-0.0	-0.3	0.0	0.2	0.2	-1.4	-1.1	1.3	0.6	1.1	-0.4	0.5	0.5
Vitamin and mineral supplements	0.9	1.2	4.6	-2.1	0.1	0.6	-0.2	1.1	1.3	0.7	0.5	0.7	0.8	1.0	0.6	-2.1	-1.5	0.8
Supplements: Zinc	2.0	2.2	5.6	-0.3	2.2	-1.2	-1.5	-0.7	-0.8	-1.1	0.7	1.8	2.0	0.9	2.4	2.2	1.7	-0.2
Medication: Co-codamol	2.4	2.7	6.2	-2.5	2.5	-1.7	-1.2	-1.5	-1.9	-1.8	-0.7	1.4	1.7	0.5	2.1	1.1	0.4	-2.0
Medication: Metformin	0.4	0.6	1.8	0.8	0.5	-0.0	-1.3	1.0	0.9	0.3	0.8	-0.1	-0.2	1.4	0.6	1.0	0.9	0.4
Diabetes (father)	1.7	2.1	5.2	-1.5	0.5	2.0	1.3	2.2	2.3	2.1	0.7	0.4	-0.6	1.5	-0.3	-0.8	-0.4	2.1
Diabetes (mother)	0.3	0.4	1.3	-0.1	-0.1	0.7	0.4	0.5	0.8	0.8	-1.2	-1.1	-0.4	0.1	-0.5	0.3	-0.2	0.7
Severe depression (siblings)	0.7	0.7	4.2	1.4	0.3	0.4	0.2	0.9	0.9	0.5	-0.5	-0.3	0.4	0.6	0.3	2.0	1.4	0.4
Pack years adult smoking proportion	0.8	1.2	4.1	-1.3	-0.6	1.4	2.0	1.3	0.7	1.1	1.0	-1.0	0.2	-1.3	-0.5	-0.6	-1.2	0.6
Impedance of leg (right)	0.7	3.3	8.2	1.6	1.7	-2.4	-1.4	-2.4	-2.9	-2.6	-0.6	-0.2	2.0	-1.6	1.5	0.0	-0.7	-2.5
Leg fat-free mass (left)	0.7	3.9	11.1	-1.2	-1.6	2.8	1.2	3.0	3.3	3.0	1.2	-0.0	-1.3	0.9	-1.3	0.4	1.7	2.8
Trunk fat percentage	0.3	1.0	4.1	-1.7	0.4	0.9	-0.4	1.3	1.2	1.0	-0.1	0.6	0.8	0.8	0.5	0.5	2.0	0.7
Hand grip strength (right)	0.5	1.4	7.3	2.7	-0.2	-0.2	-0.5	0.0	-0.0	-0.1	2.3	0.2	0.2	1.2	0.2	1.6	1.9	-0.3
Townsend deprivation index at recruitment	0.5	0.7	3.9	-1.8	0.8	-0.7	-0.7	0.1	-0.3	-0.5	0.1	-0.6	-0.8	-1.1	-0.1	2.0	0.2	-0.1
Current tobacco smoking	0.7	1.1	2.8	-1.5	1.3	-1.2	-1.7	-0.6	-1.4	-1.1	0.7	0.0	0.6	0.2	0.9	1.2	0.2	-1.2
Average weekly fortified wine intake	0.9	1.0	2.3	0.1	-0.4	1.2	1.2	1.2	1.3	1.2	0.3	0.5	-1.0	-0.9	-1.2	-1.1	-1.0	1.5
Maternal smoking around birth	0.8	1.1	6.0	-1.0	1.3	-1.0	-1.8	0.7	0.2	-0.7	2.5	-0.3	0.1	0.0	1.0	1.1	-0.1	0.3
Fed-up feelings	1.2	2.3	5.3	1.3	-0.3	2.3	1.2	2.1	2.2	2.3	-0.5	-2.1	-0.5	0.3	-0.3	-1.4	-0.4	1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	7.2	-1.7	0.0	0.1	0.7	-0.8	-0.4	-0.1	-1.4	-1.5	-0.7	-2.7	-0.6	0.4	0.0	-0.5
Relative age voice broke	1.3	2.0	8.2	0.1	2.9	-1.3	-1.7	-0.5	-0.7	-1.1	1.9	1.4	2.0	0.0	2.0	1.0	0.4	-0.4
Taking other prescription medications	0.6	1.0	2.0	-0.3	-0.1	-1.1	-0.8	-1.1	-1.1	-1.2	-0.6	-1.0	-0.3	-1.2	-0.3	-1.3	-1.3	-1.4
Age when periods started (menarche)	1.6	3.9	10.6	1.7	1.0	-3.0	-1.6	-2.5	-2.7	-3.1	-0.8	0.4	1.1	-1.6	0.7	-1.2	-1.6	-3.2
Bilateral oophorectomy (both ovaries removed)	0.5	0.5	2.3	0.3	-0.3	0.9	-0.2	1.2	1.5	1.3	-0.2	0.1	0.5	0.0	0.2	-0.5	0.4	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	2.0	-0.1	-0.2	-0.5	-0.6	-0.3	-0.2	-0.4	0.9	-0.2	0.8	-0.4	0.8	0.7	0.9	-1.4
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	4.2	-0.6	-1.8	-0.0	0.5	-0.0	-0.2	0.1	-0.4	-0.3	-0.9	-0.5	-0.9	-1.9	-2.0	-0.6
Qualifications: CSEs or equivalent	0.7	0.9	5.3	-0.6	0.6	-0.6	0.3	-1.4	-1.3	-0.6	-2.3	0.0	0.3	0.0	-0.1	-1.1	-0.3	-1.0
Serious illness, injury or assault to yourself	2.0	2.4	11.2	0.2	0.4	-1.6	-1.1	-1.6	-2.0	-1.7	-3.4	-1.5	0.3	-2.5	-0.5	-0.3	-0.5	-1.7
High blood pressure	0.2	0.5	1.6	0.1	-0.4	1.0	0.4	0.8	1.2	1.3	-0.7	-0.5	0.0	0.6	0.1	-0.3	0.7	1.1
Hayfever, allergic rhinitis or eczema	1.1	2.4	7.1	-0.8	-0.8	1.3	2.3	-0.4	-0.2	0.7	-1.9	-1.9	-1.3	-2.5	-1.1	-2.7	-1.7	0.3
Multivitamins +/- minerals	0.9	1.1	4.8	1.2	1.4	-1.0	-0.5	-0.9	-1.1	-1.1	-0.4	-0.1	-0.2	-0.9	0.2	2.2	1.4	-1.2
Stomach or abdominal pain in last month	0.4	0.6	5.0	0.2	0.8	-0.8	-2.2	0.3	-0.3	-0.3	0.9	0.3	0.2	0.1	0.6	0.5	0.4	0.2
Supplements: Glucosamine	1.0	1.3	3.9	-0.7	-0.5	-1.0	0.5	-1.9	-1.7	-1.4	-2.0	0.2	-0.4	-0.7	-0.9	0.8	0.9	-1.5
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	7.4	-1.3	-0.2	-0.2	-0.7	0.5	0.7	0.0	2.7	1.8	0.7	0.2	0.6	-0.5	0.1	0.6
Medication: Atenolol	1.3	1.6	6.1	0.9	-0.8	0.7	1.8	0.6	0.5	0.5	0.4	-0.9	-2.0	-0.9	-1.9	-1.3	-2.5	0.8
Medication: Levothyroxine sodium	0.6	1.0	4.2	-0.5	-1.6	-0.3	0.1	0.0	0.0	-0.1	0.6	-0.5	-1.8	-1.7	-2.0	-0.7	-1.1	-0.3
Sitting height	0.3	2.3	5.9	1.6	-0.8	2.0	1.0	2.0	2.4	2.0	0.6	-1.9	-0.7	-0.9	-0.9	-0.3	0.7	2.4
Chronic bronchitis/emphysema (father)	0.4	0.5	1.4	0.7	0.4	-0.8	-1.2	-0.1	-0.5	-0.6	0.6	1.1	0.5	1.0	0.6	0.4	0.8	-0.7
High blood pressure (mother)	1.4	2.0	5.9	0.0	2.4	-1.8	-0.9	-1.9	-1.3	-1.7	-0.8	0.7	1.1	-0.1	1.6	-1.4	-2.0	-1.1
Body mass index (BMI)	0.7	3.1	7.4	-1.9	-1.1	2.1	0.3	2.6	2.7	2.4	0.4	0.7	-0.4	2.3	-0.5	0.6	2.2	2.2
Impedance of leg (left)	0.7	3.5	8.0	2.0	1.8	-2.4	-1.5	-2.3	-2.8	-2.6	-0.8	-0.4	1.8	-1.3	1.5	-0.3	-0.9	-2.7
Leg predicted mass (left)	0.7	4.0	11.2	-1.2	-1.6	2.8	1.3	3.0	3.3	3.0	1.2	0.0	-1.2	0.9	-1.3	0.4	1.6	2.9
Trunk fat mass	0.4	1.6	4.3	-1.6	-0.5	1.6	0.1	1.9	2.1	1.8	-0.0	0.2	-0.0	1.1	-0.3	0.4	2.0	1.5
Waist circumference	0.6	2.2	7.5	-1.8	-0.9	1.5	-0.2	2.0	2.1	1.8	0.7	0.9	-0.1	1.5	-0.4	1.1	2.7	1.6
Number of incorrect matches in round	0.4	0.7	3.7	1.9	0.6	-0.1	-0.0	-0.2	0.1	0.0	-0.3	0.5	1.9	0.7	1.1	-0.3	0.3	0.5
Past tobacco smoking	0.3	0.6	1.9	-0.2	1.4	0.4	0.3	0.6	0.5	0.4	0.7	1.0	1.0	-0.3	0.8	0.9	1.1	0.7
Alcohol usually taken with meals	1.0	1.6	4.6	0.5	-0.7	1.8	0.3	2.1	2.1	1.9	1.6	0.1	0.4	-0.7	0.5	-1.1	-0.3	1.5
Nervous feelings	0.7	1.3	6.3	-0.0	-1.0	-0.4	0.1	-0.7	-0.8	-0.2	-0.6	-1.4	-1.6	-1.1	-1.1	-1.8	-2.5	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	5.2	-0.5	-0.0	-0.7	-0.5	-0.8	-0.7	-0.6	-0.0	-1.4	-1.3	-2.3	-0.6	0.3	-0.8	-0.9
Hearing difficulty/problems with background noise	0.4	0.7	2.0	-1.4	-0.6	-0.4	-0.7	0.1	-0.3	-0.4	1.4	0.8	-1.4	-0.6	-0.9	-0.2	-1.0	-0.8
Hair/balding pattern: Pattern 2	0.9	1.1	3.9	1.9	0.7	0.3	-0.0	0.7	0.3	0.3	0.1	0.1	2.0	-1.0	1.6	0.7	1.8	0.9
Had menopause	1.1	1.4	5.3	-0.6	-2.3	1.3	0.5	1.0	1.2	1.4	-1.4	-1.3	-0.5	-0.3	-1.6	-0.8	-0.5	0.7
Had other major operations	0.8	0.9	4.5	0.0	-1.2	0.5	-0.3	0.6	0.8	0.6	-1.0	-0.5	-2.1	0.4	-2.1	0.1	0.1	0.7
Forced vital capacity (FVC)	0.1	0.4	1.2	0.3	0.5	1.0	0.5	0.7	0.8	0.8	-0.6	-0.5	0.8	0.2	0.5	-1.1	0.1	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.6	4.0	-0.2	-0.4	0.4	0.1	0.6	0.8	0.6	2.0	-1.0	0.3	-1.1	0.4	0.0	0.0	-0.3
Ever unenthusiastic/disinterested for a whole week	1.5	1.9	4.4	0.5	0.4	-1.9	-0.6	-2.0	-2.0	-2.0	-1.1	-0.8	0.7	-2.1	0.9	-0.5	-1.0	-1.9
Qualifications: None of the above	0.1	0.2	0.7	-0.7	-0.1	-0.2	-0.3	0.5	0.1	-0.1	0.1	-0.4	-0.7	0.3	-0.3	0.7	-0.8	-0.1
Financial difficulties in last 2 years	2.0	2.6	6.6	0.1	1.6	-2.6	-1.9	-2.0	-2.4	-2.4	-1.2	0.3	0.5	-2.0	0.9	0.5	-0.3	-2.2
Mouth/teeth dental problems	0.8	1.2	3.6	-0.4	0.9	-1.1	0.3	-1.9	-1.9	-1.5	-1.5	-0.2	1.1	-0.1	0.8	-0.9	-0.9	-0.5
Heart attack	0.8	1.0	4.9	2.2	-0.9	0.9	0.6	1.0	0.9	0.9	0.2	-0.9	-1.3	-0.1	-1.2	-0.4	-1.1	0.9
Allergy	0.8	1.8	6.6	-0.2	0.5	-0.1	-1.8	1.2	0.9	0.4	1.7	2.0	1.0	2.6	0.6	2.0	1.3	0.6
Pain all over the body in last month	1.9	2.0	5.1	-0.9	1.9	-1.9	-2.3	-1.0	-1.4	-1.8	0.4	1.0	1.7	-1.3	2.1	0.5	-0.4	-0.1
Diabetes (self-reported)	0.6	0.9	2.4	0.1	-0.3	1.5	0.7	1.6	1.5	1.5	-0.4	-1.1	-0.7	-0.6	-0.3	0.2	0.4	0.8
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	3.0	0.0	-0.5	0.4	1.2	-0.3	-0.3	0.2	-0.6	-0.4	-0.2	-1.7	-0.1	-1.6	-0.7	0.2
Medication: Ramipril	0.8	1.0	4.3	2.0	-1.4	0.4	0.4	0.3	0.5	0.4	0.5	-0.1	-0.9	0.7	-0.5	-1.5	-2.1	-0.4
Medication: Simvastatin	0.5	0.8	3.8	1.9	-0.3	-0.9	-0.5	-0.3	0.0	-0.5	0.3	0.8	0.3	1.8	0.4	-1.1	-0.7	-0.4
Fluid intelligence score	0.8	1.7	10.6	-3.2	-1.4	0.9	1.8	0.4	0.6	0.7	1.5	0.3	-1.3	-0.7	-1.6	-0.8	-0.8	0.3
Illnesses of siblings	0.3	0.5	4.6	-0.6	0.1	-0.5	-0.2	-0.3	-0.7	-0.5	0.5	0.3	-0.0	-2.1	-0.1	0.1	-0.3	-0.6
Neuroticism score	0.4	0.8	1.9	0.7	-1.0	1.0	-0.5	1.4	1.4	1.3	0.1	-1.3	-0.7	-0.1	-0.4	-0.6	-0.3	0.9
Weight	0.8	4.1	11.6	-1.6	-1.4	2.8	0.8	3.1	3.4	3.1	0.5	-0.2	-0.8	1.4	-1.0	0.6	2.3	2.8
Impedance of arm (right)	0.7	3.0	7.5	-0.8	2.5	-1.8	-0.7	-2.2	-2.7	-2.2	-1.4	-0.2	1.7	-2.5	1.4	-0.0	-0.9	-2.0
Arm fat percentage (right)	0.4	1.7	4.7	-2.2	-0.3	1.5	-0.0	1.8	1.8	1.7	-0.3	0.8	0.3	1.4	0.1	0.1	1.8	1.5
Trunk fat-free mass	1.2	7.1	20.2	0.5	-3.1	3.5	1.8	3.9	4.5	4.0	1.2	-0.9	-2.4	1.7	-2.5	0.1	1.1	3.5
Hip circumference	0.4	1.9	4.6	-1.2	-1.1	1.8	0.3	2.0	2.1	1.9	0.1	0.7	-0.5	1.3	-0.7	0.3	2.1	1.7
Time employed in main current job	0.4	0.5	2.6	0.9	0.6	-0.4	-0.4	-0.7	-0.3	-0.4	-0.3	1.6	0.7	0.2	0.9	-0.2	-0.9	-0.7
Alcohol intake versus 10 years previously	0.8	1.2	3.5	0.2	-0.2	-1.4	0.1	-1.9	-1.5	-1.5	-1.6	-0.9	-0.4	-0.5	-0.2	-1.0	-1.5	-1.3
Father’s age at death	0.3	0.4	1.5	0.0	-1.1	0.5	0.4	0.4	0.5	0.6	0.1	0.4	0.1	0.5	-1.2	0.6	0.8	-0.4
Worrier / anxious feelings	0.3	0.6	2.2	-0.6	-1.5	0.3	-0.0	0.5	0.5	0.5	-0.2	-1.2	-1.1	-1.5	-1.1	0.1	0.4	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	2.7	-0.9	-0.8	0.3	0.6	-0.3	-0.2	0.2	-1.0	-1.3	-0.9	-1.6	-0.8	0.1	-0.1	0.3
Falls in the last year	0.8	1.1	2.9	0.7	-0.9	-1.2	-0.0	-1.6	-1.3	-1.2	-1.6	-0.6	-0.1	-0.7	-0.9	-0.4	-0.7	-1.7
Hair/balding pattern: Pattern 3	0.3	0.5	1.6	0.1	-0.1	0.6	0.5	0.9	1.0	0.6	0.2	-0.4	-0.9	0.6	-0.4	1.2	0.2	1.1
Number of live births	0.8	1.2	9.5	3.1	0.3	0.5	-0.3	0.7	1.1	0.6	-0.5	-1.4	-0.2	-0.5	0.3	0.8	0.8	1.2
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.4	0.6	-0.0	0.9	0.3	0.6	0.7	0.8	-0.5	-0.2	0.1	0.7	-0.2	-1.2	-0.1	0.6
Pulse rate	0.3	0.5	2.3	0.9	1.5	0.4	-1.0	0.9	0.8	0.7	0.2	0.6	-0.1	0.7	0.6	-0.1	0.6	0.7
Happiness	0.7	0.8	3.2	-1.8	-0.6	0.9	0.0	0.9	0.9	1.1	0.4	0.8	-1.0	0.5	-0.6	-0.1	-0.4	1.4
Noisy workplace	0.7	0.8	4.0	-0.3	0.1	0.3	-0.7	0.5	0.2	0.3	-0.5	-1.1	-0.5	-1.3	-0.3	2.0	1.9	0.4
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.8	0.5	0.4	-0.4	-0.3	-0.7	-0.5	-0.5	0.6	0.2	-1.2	-0.5	-0.1	-1.3	-1.4	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	5.0	-0.0	2.2	0.2	0.5	-0.1	0.1	0.0	-0.7	0.7	1.2	0.2	1.3	0.5	0.6	0.0
Mouth/teeth dental problems: Dentures	3.0	5.1	17.6	0.9	1.3	0.2	-2.3	2.8	2.4	0.9	4.2	1.5	1.5	1.2	2.0	3.5	3.7	1.4
Asthma	0.6	1.1	4.6	1.7	-0.3	0.0	1.0	0.2	-0.1	-0.1	0.5	-1.9	-0.6	-2.1	-0.3	-1.5	-1.3	0.2
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	3.4	1.3	-1.2	0.7	1.4	0.3	0.4	0.6	0.1	-0.7	-0.3	-1.9	-1.0	-0.0	0.4	0.1
Medication: Cholesterol lowering	0.6	1.0	5.3	0.8	0.2	-0.7	-0.3	-0.1	0.0	-0.5	1.0	2.0	-0.2	2.3	0.1	-1.0	-1.4	-0.1
Depression (self-reported)	1.9	2.2	6.7	0.1	1.1	-1.6	-1.9	-1.5	-1.3	-1.5	-0.4	0.0	1.7	-0.5	1.6	2.5	2.6	-0.9
Medication: Lansoprazole	1.8	2.0	5.8	-0.6	1.2	-2.0	-1.0	-1.9	-2.2	-2.1	-0.8	1.1	1.4	0.2	0.8	0.1	0.4	-2.4
Prospective memory result	0.6	0.8	2.2	1.5	-0.5	-0.1	-0.7	0.8	0.3	0.1	1.3	-1.1	0.4	-1.0	0.4	1.2	1.4	0.3
Lung cancer (father)	1.3	1.5	4.9	1.3	-0.9	1.2	1.0	1.1	1.2	1.2	-0.8	-2.2	-0.8	-0.1	-1.2	-1.5	-1.1	1.6
Illnesses of mother	0.3	0.4	1.6	0.6	-1.1	0.5	0.3	0.3	0.1	0.3	-0.7	-0.7	-0.0	-0.5	-0.3	0.2	1.3	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	3.6	0.9	-0.6	1.9	0.8	1.5	1.6	1.7	0.1	-0.4	-0.1	1.4	-0.5	-1.3	0.2	1.5
Pulse wave Arterial Stiffness index	0.5	0.6	1.3	-0.0	-0.4	0.7	-1.0	1.1	0.9	1.0	-0.6	0.6	-0.3	1.0	-0.8	-0.1	0.4	1.1
Impedance of arm (left)	0.9	4.0	9.5	-1.6	2.8	-2.0	-0.4	-2.7	-3.1	-2.5	-1.0	0.1	1.9	-2.9	1.6	-0.1	-1.0	-2.3
Arm fat mass (right)	0.7	2.8	7.1	-2.2	-1.2	2.2	0.6	2.4	2.7	2.5	0.1	0.4	-0.4	1.6	-0.7	0.2	1.9	2.0
Trunk predicted mass	1.2	6.9	19.5	0.4	-3.1	3.4	1.7	3.8	4.4	3.9	1.3	-0.9	-2.4	1.7	-2.5	0.1	1.1	3.4
Standing height	0.2	2.0	4.9	0.6	-1.2	1.8	1.0	2.0	2.2	1.9	0.8	-1.7	-1.0	-1.4	-1.5	0.1	0.4	1.7
Length of working week for main job	0.6	0.6	4.9	-2.2	0.4	0.6	1.3	0.3	0.5	0.3	-0.1	0.3	-0.2	0.9	0.3	-0.7	-0.5	0.4
Exposure to tobacco smoke at home	0.6	0.7	2.4	-1.1	-0.1	1.2	1.4	0.7	0.7	0.9	0.1	-0.4	0.4	0.2	-0.2	-0.1	0.9	1.5
Breastfed as a baby	0.9	1.2	5.5	0.7	-0.7	1.6	2.3	0.4	0.9	1.2	-1.0	0.1	-0.3	0.5	-0.4	-1.2	-0.9	1.4
Tense / ‘highly strung’	0.3	0.5	1.9	-0.4	0.1	0.0	-0.7	0.2	-0.0	0.0	-0.0	-1.0	-1.4	-1.4	-0.5	0.6	-0.4	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	6.1	-0.6	0.9	-1.1	-1.3	-0.4	-0.6	-0.8	0.7	0.5	1.2	0.1	1.4	2.5	2.5	-0.6
Hair/balding pattern: Pattern 4	0.5	1.2	3.3	-1.2	-0.2	-1.3	-0.6	-1.6	-1.3	-1.2	-1.1	0.6	-0.8	1.8	-1.0	0.9	0.4	-1.4
Birth weight of first child	0.4	0.8	2.4	-0.2	-0.9	0.7	-0.6	1.0	0.7	0.7	1.3	0.1	-1.6	0.9	-1.1	1.0	0.9	0.3
Peak expiratory flow (PEF)	0.1	0.2	0.9	0.5	1.0	-0.2	-0.1	-0.3	-0.3	-0.4	0.5	0.6	0.4	0.1	0.5	-0.2	-0.3	-0.3
Pulse wave reflection index	0.5	0.7	2.1	0.4	-0.4	-1.1	-1.3	-1.0	-1.4	-1.1	-0.2	0.5	-0.1	0.2	-0.3	0.8	0.1	-1.2
Ever highly irritable/argumentative for 2 days	1.0	1.2	2.6	1.2	0.9	-1.3	-1.0	-1.2	-1.6	-1.5	-0.7	-0.1	0.8	-1.3	0.6	-1.4	-1.3	-0.6
Loud music exposure frequency	0.8	0.9	2.5	-1.2	1.3	-1.2	-0.9	-0.6	-1.0	-1.2	0.7	0.8	0.5	-0.0	0.7	1.6	0.7	-0.8
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	4.3	0.2	1.5	-2.1	-1.2	-1.9	-1.7	-2.0	0.6	1.2	0.3	-0.3	1.1	-0.3	-0.8	-1.3
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	4.6	-0.4	-0.9	0.3	0.5	0.1	0.4	0.5	-0.3	-1.1	-2.1	-0.7	-1.7	-0.7	-1.5	-0.2
Blood clot in the leg (DVT)	0.8	1.1	3.0	-0.1	0.9	-1.7	-0.7	-1.0	-1.3	-1.7	-0.1	1.0	0.8	0.3	1.1	-0.7	-0.7	-1.4
Medication: Paracetamol	0.3	0.5	1.2	0.0	-0.5	0.9	0.2	0.7	0.9	1.0	-0.4	-0.2	-1.1	-0.9	-1.0	0.0	0.2	0.4
Headache pain in last month	0.1	0.3	1.0	0.1	0.1	0.6	-0.1	0.8	0.6	0.6	-0.1	-0.4	-0.3	-1.0	-0.5	-0.3	0.7	-0.1
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	5.1	-0.8	-0.0	0.4	0.7	-0.3	-0.4	-0.0	-1.0	-1.3	0.7	-2.3	-0.0	0.5	1.2	-0.1
Glaucoma (self-reported)	0.3	0.3	1.2	0.5	-0.9	-0.3	-0.4	-0.2	0.1	-0.2	0.5	0.2	1.1	-0.4	0.2	0.4	0.9	-0.9
Gout (self-reported)	0.4	0.6	2.5	1.0	-0.2	-0.5	-1.1	-0.1	-0.3	-0.2	0.6	-0.7	-0.2	-0.9	0.1	1.6	1.3	0.2
Hypothyroidism/myxoedema (self-reported)	1.4	2.7	9.1	-1.1	-2.4	0.5	1.2	0.3	0.5	0.5	0.5	-2.4	-2.8	-2.6	-3.0	0.1	-0.9	0.3
Medication: Amlodipine	0.4	0.5	1.3	-0.3	-1.1	-0.7	-0.0	-0.8	-0.9	-0.7	0.5	0.2	-0.9	1.0	-0.9	0.4	0.4	-0.9
Medication: Ventolin 100micrograms inhaler	0.9	1.1	2.9	1.2	1.1	-1.7	-1.1	-1.0	-1.3	-1.7	0.1	-0.5	0.2	-1.1	0.8	0.5	-0.8	-1.0
Birth weight	0.4	1.0	3.4	-0.4	-1.5	0.7	-0.1	0.4	0.5	0.7	-1.0	-0.1	-1.8	-0.3	-1.8	1.1	1.1	0.5
Chronic bronchitis/emphysema (mother)	1.3	1.5	6.8	-0.6	2.6	-1.1	-0.9	-1.0	-1.5	-1.2	1.0	0.7	1.4	-1.1	1.8	-0.2	-0.9	-0.1
High blood pressure (siblings)	0.1	0.2	0.5	0.1	-0.4	0.4	-0.0	0.5	0.6	0.5	0.1	-0.6	-0.3	0.6	-0.0	0.7	0.2	0.7
Forced vital capacity (FVC), Best measure	0.3	1.1	3.6	0.2	-0.3	1.9	1.1	1.4	1.5	1.6	-0.1	-0.9	0.4	0.7	-0.2	-1.1	0.4	1.5
Body fat percentage	0.3	1.3	5.1	-1.7	0.3	1.0	-0.6	1.5	1.4	1.2	-0.1	0.7	0.8	1.3	0.5	0.5	2.3	0.9
Leg fat percentage (right)	0.3	1.3	6.0	-0.8	0.1	0.4	-1.2	1.1	1.1	0.9	-0.3	0.8	1.1	1.9	0.9	0.6	2.5	0.7
Arm fat-free mass (right)	1.0	5.1	15.7	-0.1	-2.7	3.0	1.1	3.5	4.0	3.4	1.2	-0.4	-1.4	1.6	-1.8	0.2	1.6	3.0
Exposure to tobacco smoke outside home	0.9	1.2	2.9	-1.0	1.2	-1.6	-1.0	-1.4	-1.7	-1.5	-0.1	0.5	1.1	0.1	1.1	0.7	0.3	-1.5
Comparative body size at age 10	0.3	0.7	3.1	0.5	-0.3	-0.9	-1.8	-0.3	-0.6	-0.6	-0.8	0.9	-0.2	0.2	-0.5	1.4	1.1	-1.0
Number of full brothers	0.2	0.3	0.9	0.8	0.1	0.3	0.6	0.1	0.4	0.2	0.2	0.3	-0.2	0.7	-0.1	1.0	0.9	0.2
Worry too long after embarrassment	1.4	2.4	7.0	-0.2	-1.0	2.5	0.9	2.3	2.4	2.6	0.1	-0.8	-0.9	0.9	-0.9	0.3	0.8	2.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	2.6	0.3	-0.8	0.0	-0.4	0.4	0.4	0.2	1.6	0.2	0.2	-0.0	0.0	1.6	1.6	-0.4
Wheeze or whistling in the chest in last year	0.8	1.5	5.9	0.7	2.3	-0.0	-0.8	1.0	0.3	-0.0	1.4	0.9	2.0	-0.8	2.4	0.6	1.1	0.1
Number of children fathered	0.7	0.8	5.4	2.3	1.2	-0.1	0.5	-0.0	0.5	-0.1	1.0	0.0	0.9	0.1	1.3	-1.1	0.3	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	3.3	1.3	-1.6	0.2	-0.3	0.4	0.7	0.5	0.4	0.2	-1.8	-0.4	-1.5	1.7	-0.1	-0.2
Age at first live birth	0.5	1.0	2.8	0.7	-1.5	0.2	0.6	-0.4	-0.1	0.2	-0.4	-0.5	-1.7	-0.7	-1.5	-1.6	-1.6	0.6
Pulse wave peak to peak time	0.5	0.6	1.8	0.3	0.2	-0.7	1.0	-1.1	-0.9	-1.0	0.7	-0.7	0.4	-1.3	0.7	0.2	-0.3	-1.2
Health satisfaction	1.0	1.3	3.3	-1.8	1.2	-1.4	-1.5	-1.0	-1.3	-1.3	-1.0	0.2	0.9	-1.5	0.9	1.2	0.2	-0.4
Shortness of breath walking on level ground	0.3	0.4	2.3	-0.0	1.5	-0.4	-1.2	0.5	0.1	-0.1	-0.4	-0.2	-0.0	-0.2	0.5	-0.3	-0.2	0.9
Qualifications: College or University degree	0.3	0.8	2.1	-0.2	-0.6	0.9	1.4	0.3	0.4	0.6	-0.6	-0.4	-1.2	-0.5	-1.0	-1.4	-1.3	1.4
Eye problems/disorders: None of the above	0.6	0.7	2.0	-1.4	1.4	-0.6	0.4	-1.0	-1.0	-0.7	-0.3	0.1	0.6	-1.3	0.3	0.2	-0.9	-0.3
Mouth/teeth dental problems: Loose teeth	3.5	4.1	11.2	-3.0	1.6	-2.4	-1.1	-2.2	-2.5	-2.7	-0.2	1.2	1.4	-1.3	1.3	2.3	1.3	-3.3
Emphysema/chronic bronchitis	1.3	1.5	2.8	0.7	1.6	-1.2	-1.5	-0.4	-0.9	-1.2	1.2	1.6	1.4	0.7	1.7	1.2	1.5	-0.7
Medication for pain relief, constipation, heartburn	0.3	0.5	2.7	-1.6	0.2	0.0	0.8	-0.1	-0.2	-0.2	1.0	0.1	1.4	0.4	0.9	0.2	0.5	0.1
Neck or shoulder pain in last month	0.2	0.3	1.2	0.4	-0.0	-0.9	-0.5	-0.5	-0.8	-1.1	0.2	-0.0	-0.4	-0.8	-0.3	0.0	-0.7	-0.6
Medication: Blood pressure	0.4	0.8	3.8	-0.1	-0.3	0.1	-0.0	0.6	0.6	0.4	1.0	1.3	-0.4	1.9	0.1	-1.3	-1.3	0.6
Angina (self-reported)	1.2	1.6	4.3	1.2	-0.3	-1.1	0.3	-1.3	-0.9	-1.2	-1.5	-1.7	-2.1	-1.2	-1.4	-0.3	-1.7	-1.1
Migraine (self-reported)	0.4	0.5	1.7	-0.9	-0.3	0.5	0.5	-0.4	-0.1	0.5	-1.1	0.3	-0.8	1.0	-1.3	-0.0	1.0	0.3
Medication: Ibuprofen	0.6	0.7	3.9	2.0	-1.0	0.7	1.1	0.7	0.6	0.7	0.6	-0.5	-0.3	-1.0	-0.9	-0.1	0.3	0.5
Medication: Allopurinol	0.7	1.0	3.1	1.6	-0.0	-0.6	-1.4	-0.2	-0.2	-0.3	0.0	-0.9	0.7	-1.7	0.6	1.5	1.8	0.2
Medication: Omeprazole	0.4	0.5	1.2	1.1	0.3	-1.0	-1.1	-0.5	-0.6	-0.7	-0.5	-0.3	0.5	-1.0	0.5	0.3	0.2	-0.9
Medication: Seretide 50 evohaler	3.7	4.2	10.2	2.8	1.3	-2.6	-1.4	-2.8	-3.2	-2.8	-1.8	-1.0	1.6	-1.8	1.5	-0.4	-0.5	-2.5
Mean time to correctly identify matches	1.9	3.7	13.5	-0.4	-2.7	1.4	2.1	0.4	0.4	1.1	-1.4	-1.5	-1.9	-0.5	-2.1	-3.6	-3.7	0.6
Heart disease (mother)	0.8	1.0	4.0	-1.0	-1.7	0.8	1.6	0.1	0.2	0.6	-1.3	-0.4	-0.8	-0.3	-2.0	0.0	0.5	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.8	2.1	12.5	-1.0	1.0	-0.1	0.3	0.3	0.4	-0.0	2.3	2.9	0.9	3.5	1.3	-0.5	-0.6	0.6
Whole body fat mass	0.4	1.9	5.1	-1.6	-0.5	1.6	-0.1	2.1	2.3	1.9	0.3	0.5	-0.2	1.4	-0.4	0.4	2.0	1.6
Leg fat mass (right)	0.5	1.9	5.2	-0.9	-0.6	1.3	-0.6	2.0	2.1	1.7	0.4	0.8	0.3	2.1	0.1	0.6	2.3	1.6
Arm predicted mass (right)	0.9	4.4	13.1	0.2	-2.5	2.7	1.0	3.1	3.6	3.1	1.0	-0.5	-1.6	1.5	-1.9	0.0	1.3	2.8
Pulse rate, automated reading	0.2	0.8	2.5	-0.2	1.2	-0.9	-0.9	-0.9	-1.0	-0.7	-1.6	-0.9	0.3	0.5	0.7	0.8	0.2	-1.0
Alcohol intake frequency.	0.5	1.1	2.3	-0.3	-0.9	1.5	1.4	0.7	1.0	1.5	-0.7	-0.8	-0.8	-0.3	-0.7	-1.5	-1.5	1.1
Comparative height size at age 10	0.2	1.0	3.7	0.5	-0.0	1.2	0.0	1.6	1.9	1.3	-0.0	-1.5	-0.1	-0.9	-0.1	0.4	1.1	1.0
Number of full sisters	0.5	0.6	2.0	0.1	-0.4	0.7	0.9	-0.3	-0.3	0.3	-0.8	-0.6	-1.4	-0.4	-1.0	-0.5	-0.9	1.1
Suffer from ‘nerves’	0.8	1.3	5.1	0.4	-0.1	-1.2	-0.2	-1.1	-1.0	-1.1	0.3	-1.3	-1.1	-1.8	-0.5	-1.2	-2.3	-1.0
Overall health rating	0.5	1.0	3.0	-1.1	-0.6	-1.1	-0.9	-0.7	-1.2	-0.9	-1.0	-0.5	-0.5	-1.4	-0.4	-1.1	-1.7	-0.9
Chest pain or discomfort	1.3	1.9	4.4	1.5	2.0	-2.1	-1.4	-1.3	-1.9	-2.1	0.3	1.3	0.3	-0.5	1.4	0.4	-0.4	-1.1
Had major operations	0.6	0.7	2.6	0.9	0.5	0.2	0.8	0.0	0.0	0.0	-0.6	-1.0	-0.2	-1.2	-0.4	-1.5	-1.6	0.7
Age at last live birth	0.3	0.4	2.2	0.2	-1.5	-0.1	0.4	-0.7	-0.4	0.0	0.2	0.2	-0.8	-0.4	-0.9	-1.2	-0.5	0.1
Family relationship satisfaction	0.8	1.0	6.7	-2.6	-1.1	0.9	1.2	0.4	0.6	0.9	-0.8	0.1	-0.9	0.3	-1.3	0.3	-0.3	0.6
Leg pain on walking	2.3	2.9	8.8	0.0	2.4	-1.7	-3.0	-0.2	-0.5	-1.3	0.6	2.0	2.1	1.7	2.2	1.7	2.1	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	2.7	-1.0	-0.4	0.6	0.5	0.2	-0.2	0.6	-0.7	-0.5	0.2	-1.1	-0.6	-1.6	-0.3	0.0
Commuting to job workplace: Car/motor vehicle	1.3	1.5	5.7	2.4	-0.1	-1.2	-1.1	-1.7	-1.7	-1.3	-0.9	-0.9	-0.2	-1.1	-0.1	1.3	0.9	-1.3
Illness, injury, bereavement, stress in last 2 years	1.7	2.1	5.8	-0.1	-1.3	2.2	0.8	1.9	2.4	2.3	1.7	-0.3	-0.9	0.7	-0.5	-0.7	0.2	1.9
Medication: Aspirin	1.9	2.4	4.7	0.5	1.9	-2.1	-1.9	-2.0	-1.8	-2.1	-1.0	1.3	1.4	-0.2	1.6	-0.5	-0.9	-2.2
Supplements: Vitamin C	0.9	1.0	3.2	1.6	-0.4	-0.8	0.0	-0.7	-0.9	-0.7	0.8	0.5	0.6	-1.3	0.4	1.8	1.6	-0.9
Knee pain experienced in last month	0.4	0.6	2.0	0.6	-1.0	-0.5	-1.4	-0.2	-0.2	-0.2	-0.9	-1.3	-0.6	-0.4	-0.4	0.0	1.4	-1.0
Hypertension (Self-reported)	0.2	0.6	1.8	-0.3	-0.4	1.1	0.4	1.0	1.3	1.4	-0.2	0.1	0.1	1.0	0.1	-0.6	0.6	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	3.6	0.2	0.8	-1.7	-1.1	-1.8	-1.9	-1.7	-1.5	-0.1	0.6	-1.0	0.1	0.1	0.2	-1.8
Illnesses of father: Heart disease	2.3	3.1	8.8	-0.1	-2.1	1.7	2.6	0.4	1.1	1.5	-2.3	-2.0	-2.5	-1.0	-3.0	-1.1	-1.3	1.0
Illnesses of siblings: Diabetes	0.3	0.4	1.1	0.7	-0.3	0.5	0.8	0.5	0.8	0.4	0.7	0.5	0.1	-0.5	-0.3	-1.0	-0.7	0.8
Smoking status: Previous	0.4	0.7	1.8	0.7	-1.3	-0.5	0.0	-0.8	-0.6	-0.5	-0.7	-0.5	-1.1	0.6	-0.8	-1.1	-1.4	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.8	-0.8	0.7	1.0	1.3	0.7	0.4	0.7	1.2	0.4	0.5	-0.6	0.0	0.5	0.3	0.9
Whole body fat-free mass	1.0	5.9	17.4	-0.2	-2.5	3.3	1.5	3.7	4.2	3.6	1.4	-0.5	-1.9	1.6	-2.0	0.3	1.4	3.3
Leg fat-free mass (right)	0.8	4.1	11.8	-0.9	-1.6	2.8	1.2	3.2	3.4	3.0	1.3	-0.0	-1.4	1.1	-1.3	0.3	1.5	2.8
Arm fat percentage (left)	0.4	1.5	6.6	-2.6	-0.3	1.4	0.2	1.5	1.6	1.6	-0.1	0.8	0.0	1.3	0.0	0.2	1.7	1.3
Average weekly red wine intake	2.6	3.9	7.9	0.4	-2.6	2.8	2.6	1.9	2.4	2.8	-1.1	-0.9	-1.9	-0.6	-2.1	-2.1	-1.3	1.8
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.1	-1.4	0.1	-0.7	0.4	-1.0	-1.0	-0.9	-0.6	0.7	0.7	0.1	0.4	0.3	0.6	-1.2
Mood swings	0.7	1.3	5.9	2.4	-0.5	1.2	-0.3	1.5	1.5	1.4	0.8	-0.9	0.8	0.6	0.4	-0.2	0.9	1.6
Loneliness, isolation	0.4	0.5	1.2	-0.2	0.9	1.0	0.3	1.1	1.1	1.1	-0.1	-0.6	0.1	-0.2	0.9	-0.6	0.1	0.8
Long-standing illness, disability or infirmity	0.4	0.6	2.4	0.4	-0.1	0.2	-0.4	0.6	0.5	0.4	-0.6	-1.1	-0.0	-1.0	0.2	-1.6	-1.4	0.5
Ever had bowel cancer screening	1.0	1.2	3.2	-1.4	0.8	-1.3	-1.7	-1.1	-0.8	-0.9	-0.7	1.8	0.6	0.9	0.8	0.6	1.1	-0.9
Diabetes diagnosed by doctor	0.1	0.2	0.6	0.4	0.4	0.3	-0.4	0.6	0.8	0.5	-0.2	-0.5	0.2	0.0	0.6	0.6	0.8	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	2.6	-0.6	0.6	-0.1	-0.4	-0.2	0.1	0.2	-1.1	1.1	1.6	1.1	1.4	-1.0	0.4	0.4
Friendships satisfaction	1.8	2.2	4.8	-1.7	-0.9	1.6	0.3	2.0	2.0	1.9	1.5	-0.3	-2.2	-0.2	-1.8	-0.1	-1.0	2.1
Qualifications: nursing, teaching	0.3	0.4	1.4	0.2	0.7	-0.2	0.9	-1.2	-0.7	-0.5	-0.6	-0.3	0.3	-0.7	0.5	-0.9	-0.5	-0.3
Commuting to job workplace: Walk	1.1	1.2	2.9	-0.5	-1.1	0.9	1.1	1.2	1.2	0.9	1.7	0.9	-0.3	1.6	-0.8	-1.2	-1.4	0.7
Eye problems/disorders: Cataract	1.1	1.3	4.1	0.2	-1.0	1.8	2.0	1.2	1.2	1.7	-0.3	-1.0	-0.5	0.1	-0.8	-0.4	0.3	1.7
Mouth/teeth dental problems: Mouth ulcers	0.5	0.7	4.0	0.9	-0.5	0.2	1.1	-0.6	-0.1	0.1	-2.0	-1.1	-0.8	-0.3	-1.2	-0.8	-0.5	-0.3
Medication for cholesterol	1.0	1.4	3.2	0.4	-1.5	1.4	1.2	1.5	1.3	1.1	1.8	-0.4	-1.6	0.7	-1.8	-0.1	-0.7	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.5	4.8	0.2	0.2	-1.6	-2.2	-1.2	-1.1	-1.3	-1.1	1.1	-1.6	-0.3	-1.1	1.6	0.6	-1.0
Back pain experienced in last month	0.7	1.0	2.7	-0.1	0.4	0.5	-0.8	1.5	1.6	1.0	1.3	1.1	0.5	1.6	0.8	0.7	0.8	0.6
Mineral and other dietary supplements	1.1	1.5	3.4	-1.4	-0.8	1.1	0.2	1.4	1.4	1.3	0.7	-0.3	-1.1	0.1	-1.2	-1.8	-1.9	1.7
Breast cancer (self-reported)	1.7	2.0	6.0	1.9	-1.6	0.3	0.6	-0.6	-0.3	0.0	-2.2	-2.1	-2.1	-1.6	-2.5	0.5	0.3	-0.6
Asthma (self-reported)	0.6	1.2	5.1	1.5	-0.6	0.3	1.3	0.3	0.1	0.2	0.8	-1.9	-0.8	-2.3	-0.5	-1.3	-1.1	0.4
Osteoporosis (self-reported)	1.6	2.0	5.7	1.4	0.9	-1.6	-2.4	-1.0	-1.2	-1.4	-0.8	1.8	1.6	0.8	1.7	1.2	1.3	-1.2
Osteoarthritis (self-reported)	0.5	0.7	2.2	-0.5	0.7	-1.1	-1.5	-1.0	-0.2	-0.7	-0.8	0.2	-0.2	-0.4	0.3	1.4	1.2	-0.4
Medication: Aspirin	1.9	2.4	6.1	0.5	1.8	-2.1	-2.5	-1.9	-1.7	-2.0	-1.0	1.5	1.3	-0.1	1.5	-0.3	-0.7	-1.9
Medication: Gliclazide	0.3	0.4	2.8	-0.9	0.6	0.5	0.3	0.3	0.1	0.4	-1.7	-0.2	0.1	0.4	0.5	0.3	0.6	-0.1
Illnesses of father: None of the above (group 1)	1.0	1.2	3.6	0.3	0.8	-1.5	-1.9	-0.3	-0.8	-1.4	1.6	0.9	1.3	0.5	1.3	1.2	0.3	-0.7
Smoking status: Current	0.6	0.9	2.3	-1.3	1.1	-1.1	-1.5	-0.6	-1.3	-1.0	0.8	0.1	0.8	0.3	0.9	0.8	0.2	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.7	9.9	1.3	0.1	0.3	-1.3	1.2	1.1	0.6	2.3	1.4	0.3	3.1	0.5	0.1	0.3	0.9
Whole body water mass	1.0	5.8	16.9	-0.2	-2.4	3.2	1.4	3.7	4.1	3.6	1.3	-0.5	-1.9	1.6	-1.9	0.3	1.5	3.3
Leg predicted mass (right)	0.8	4.0	11.9	-0.9	-1.5	2.8	1.1	3.2	3.5	3.0	1.4	0.0	-1.4	1.1	-1.3	0.4	1.5	2.8
Arm fat mass (left)	0.6	2.6	6.5	-2.2	-1.1	2.0	0.4	2.3	2.5	2.3	0.1	0.5	-0.6	1.7	-0.7	0.4	2.0	1.9
Number of self-reported non-cancer illnesses	0.4	0.7	5.2	0.3	-0.7	-0.3	-0.2	-0.7	-0.4	-0.3	-1.1	-0.7	-0.0	-0.7	-0.3	-2.3	-1.3	-0.3
Average weekly champagne plus white wine intake	0.5	0.7	5.0	-0.5	0.0	-0.6	-1.0	-0.5	-0.6	-0.5	1.4	2.2	-0.1	-0.0	-0.2	0.5	0.8	0.2
Miserableness	0.4	0.7	3.6	1.1	0.1	0.6	-0.4	1.2	1.1	0.8	1.9	0.2	0.1	0.4	0.3	0.1	0.8	0.9
Guilty feelings	3.2	4.7	9.1	-1.1	-2.4	3.0	2.2	2.7	3.0	3.0	-0.2	-2.1	-1.8	-1.6	-1.9	-2.2	-1.4	2.3
Wears glasses or contact lenses	0.5	0.6	1.9	1.4	-0.5	-0.6	-0.3	-0.8	-0.5	-0.6	-0.9	-1.3	-0.9	0.0	-0.8	0.4	-0.0	-0.8
Ever taken oral contraceptive pill	0.5	0.5	2.4	1.0	-0.7	-0.2	-0.9	0.8	0.6	0.0	1.6	1.1	0.1	-0.6	0.2	0.1	-0.0	0.6
Hearing aid user	0.8	0.9	2.3	-1.1	1.3	-0.1	-1.1	1.0	0.8	0.3	1.5	0.4	1.2	0.5	1.4	1.0	0.7	0.7
Mother’s age at death	0.2	0.3	1.1	0.1	-0.5	-0.0	0.8	-0.5	-0.2	-0.0	-0.8	0.2	0.0	-1.1	-0.6	0.1	0.3	-0.8
Financial situation satisfaction	0.8	1.0	2.9	-1.1	1.6	-0.8	-1.3	0.0	-0.5	-0.7	0.9	0.7	0.9	-1.7	1.5	-0.1	-1.0	-0.3
Tinnitus: Yes, now most or all of the time	3.8	4.4	9.0	-1.3	2.6	-2.8	-2.3	-2.1	-2.4	-3.0	-1.1	1.9	2.0	0.1	2.0	1.9	1.8	-2.4
Commuting to job workplace: Public transport	2.4	2.9	6.3	-0.8	-1.0	2.2	1.8	2.1	2.4	2.4	1.4	0.6	-0.6	1.1	-0.5	-2.5	-1.8	2.0
Eye problems/disorders: Glaucoma	0.6	0.8	3.9	1.1	-0.4	-0.2	-1.2	0.8	0.5	0.0	2.0	1.0	1.0	0.5	0.6	0.7	0.8	-0.3
Medication: Blood pressure	0.1	0.3	1.3	-0.1	-0.1	-0.1	-0.5	-0.1	0.2	0.3	-1.1	0.4	0.6	-0.3	0.5	0.5	1.2	-0.0
Pain type(s) experienced in last month: Hip pain	0.5	0.6	4.1	-0.5	-0.8	-0.0	0.5	0.2	0.5	0.1	0.9	-0.0	-0.6	-0.2	-0.1	-1.5	-2.0	-0.8
Supplements: Fish oil (including cod liver oil)	0.9	1.2	5.9	2.4	0.5	-1.0	-0.5	-1.0	-1.0	-1.2	-0.2	0.6	0.5	0.6	0.8	1.7	1.2	-1.2
High cholesterol (Self-reported)	1.4	2.5	8.0	1.0	0.1	-2.3	-0.7	-2.8	-2.2	-2.3	-2.2	1.1	0.3	1.2	0.4	-0.6	-1.3	-1.9
Medication: Bendroflumethiazide	0.2	0.3	1.0	-0.6	0.4	0.2	-0.9	0.9	0.7	0.6	-0.1	0.3	-0.3	1.0	0.4	-0.6	-0.4	0.7
Medication: Paracetamol	0.4	0.6	2.6	0.4	-0.6	-0.0	-0.6	-0.3	-0.1	0.1	-1.6	-0.4	-1.5	-0.5	-1.4	0.1	0.6	-0.6
Medication: Lisinopril	0.3	0.4	2.0	-0.0	1.1	-0.1	-0.3	0.4	0.6	0.3	-0.5	0.2	0.5	0.8	0.6	1.0	1.4	0.3
Medication: Atorvastatin	0.6	0.8	2.6	-1.6	-1.0	-0.1	-0.1	0.2	0.4	-0.1	0.6	0.6	-1.6	-0.8	-1.2	0.0	-1.6	-0.1
Illnesses of father: High blood pressure	1.3	1.6	5.1	-0.3	-1.1	1.2	1.9	-0.2	0.7	1.2	-2.3	-1.5	-1.4	-0.1	-1.6	-1.9	-0.4	0.7
Alcohol drinker status: Never	1.8	2.2	8.1	-1.5	-2.9	1.0	1.8	-0.3	-0.1	0.7	-1.0	-0.6	-1.5	0.0	-2.0	-2.2	-2.1	-0.2
Ever smoked	0.3	0.5	1.9	-0.3	-1.2	-0.1	-0.3	-0.2	-0.0	0.1	-0.7	-1.1	-0.9	0.5	-0.7	-0.9	-1.4	-0.3
Basal metabolic rate	1.0	5.6	16.2	-0.5	-2.3	3.2	1.4	3.6	4.0	3.6	1.2	-0.5	-1.7	1.5	-1.8	0.3	1.7	3.2
Leg fat percentage (left)	0.3	1.2	5.0	-0.5	-0.1	0.6	-1.1	1.3	1.3	1.0	-0.3	0.7	0.9	2.1	0.8	0.2	2.2	0.6
Arm fat-free mass (left)	1.3	6.6	20.1	0.1	-2.9	3.4	1.4	4.0	4.5	3.9	1.0	-0.6	-1.7	1.7	-2.1	-0.0	1.7	3.4
Number of operations (self-reported)	0.6	0.9	4.5	1.6	0.7	-0.2	-0.2	-0.3	-0.2	-0.1	-2.1	-0.6	-0.7	-0.2	-0.6	-1.7	-1.0	0.2
Average weekly beer plus cider intake	5.2	7.5	19.3	-0.0	3.7	-3.7	-4.4	-2.0	-3.0	-3.4	0.2	2.3	1.9	2.0	3.5	2.4	1.4	-3.0
Irritability	0.9	1.6	5.3	-0.8	-1.7	-0.7	-0.2	-0.9	-1.0	-0.8	-0.0	-0.3	-2.3	1.5	-2.0	-0.6	-2.0	-1.1
Risk taking	2.4	3.5	8.0	0.7	0.7	1.7	-0.4	2.7	2.3	1.8	2.6	1.7	0.8	1.8	1.0	2.0	2.8	2.5
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.7	1.6	-0.2	0.4	0.1	0.5	1.1	0.6	0.9	0.9	0.8	1.6	0.4	0.3	1.0	-0.0
Fractured/broken bones in last 5 years	0.2	0.3	1.0	-0.0	0.4	-0.1	-1.0	0.8	0.4	0.1	0.8	0.6	0.2	0.8	0.3	0.1	0.1	0.2
Age started oral contraceptive pill	0.5	0.6	1.7	0.3	-1.3	0.6	-0.5	0.8	1.3	0.8	0.3	0.6	-0.3	-0.2	-0.4	1.0	1.2	0.4
Diastolic blood pressure, automated reading	0.2	0.5	2.9	-1.2	1.7	-0.1	-0.7	-0.2	-0.5	-0.1	-0.6	-0.1	0.6	-0.0	1.0	-0.9	-0.7	0.1
Ever depressed for a whole week	4.0	4.9	12.0	0.6	1.4	-3.2	-1.8	-3.2	-3.2	-3.0	-1.3	1.3	2.2	0.0	2.0	-1.1	-1.4	-3.5
Unable to work because of sickness or disability	1.2	1.6	5.2	2.1	0.8	-1.7	-2.3	-0.6	-1.2	-1.6	-0.4	-1.1	0.9	-0.1	1.1	1.3	0.3	-1.0
Commuting to job workplace: Cycle	0.7	0.9	3.0	0.7	-1.4	0.4	-0.5	0.7	0.6	0.7	-0.8	-1.7	-1.1	-0.8	-1.0	-1.0	-0.9	1.0
Myopia	1.2	1.8	6.9	-2.1	-0.4	0.3	2.4	-1.0	-0.5	-0.0	-1.0	-0.9	-1.6	-2.6	-1.5	0.9	-1.0	0.2
Vascular/heart problems diagnosed by doctor	0.1	0.3	0.9	-0.2	-0.0	-0.6	-0.4	-0.4	-0.9	-0.9	0.9	0.9	0.3	0.3	0.1	0.3	-0.1	-0.6
Cholesterol lowering medication	1.7	2.5	6.6	1.2	-0.4	-2.2	-1.2	-2.6	-2.1	-2.1	-2.5	-0.9	-0.2	-1.3	-0.2	-0.1	-0.8	-2.0
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	1.8	0.9	0.8	-1.3	-1.4	-0.5	-0.8	-1.0	-0.9	0.1	1.0	-0.3	1.1	-0.3	-0.3	-1.1
Pain experienced in last month	0.3	0.5	4.1	-0.0	-0.0	0.9	2.0	-0.4	0.0	0.5	-0.5	-0.4	0.1	-0.4	-0.4	-0.2	-1.1	0.3
Supplements: Calcium	0.7	0.8	2.1	0.1	0.9	-0.7	-1.1	-0.9	-1.1	-0.8	-1.1	-0.1	0.8	-0.7	0.7	1.5	0.9	-0.7
Basal cell carcinoma (self-reported)	1.4	1.6	7.5	1.0	1.0	-0.8	-1.3	-0.8	-0.9	-0.9	0.9	1.9	2.7	0.4	2.2	-0.6	0.3	-0.5
Heart attack/myocardial infarction (self-reported)	0.7	0.9	5.0	2.2	-0.6	0.8	0.5	1.0	0.9	0.9	0.2	-0.8	-1.1	0.1	-0.8	-0.6	-1.1	0.9
Deep venous thrombosis (DVT) (self-reported)	1.3	1.6	4.0	0.0	1.2	-2.0	-1.0	-1.3	-1.6	-2.0	0.1	1.6	1.2	0.6	1.5	-0.4	-0.6	-1.6
Heart disease (siblings)	0.7	0.8	4.1	-1.2	0.5	-0.2	-0.8	0.3	0.3	-0.2	0.9	1.1	1.0	2.0	1.3	0.0	1.1	0.1
Alcohol drinker status: Previous	0.5	0.6	2.0	-1.4	-0.1	-1.1	-0.6	-0.8	-0.9	-1.1	0.1	0.2	0.1	-0.0	0.8	-0.1	-1.2	-0.6
Pack years of smoking	0.7	1.0	2.8	-1.2	-0.5	1.3	1.7	1.5	1.0	1.1	1.2	-0.7	0.2	-0.7	-0.3	-0.3	-1.0	0.6
Impedance of whole body	0.9	4.6	11.6	0.0	2.8	-2.5	-1.0	-2.9	-3.4	-2.9	-1.3	-0.2	2.3	-2.8	1.8	-0.3	-0.9	-2.7
Leg fat mass (left)	0.5	2.0	5.2	-0.9	-0.6	1.5	-0.5	2.2	2.3	1.8	0.3	0.6	0.1	2.2	-0.0	0.4	2.1	1.6
Arm predicted mass (left)	1.2	6.1	18.3	0.4	-2.6	3.3	1.3	3.9	4.3	3.7	1.1	-0.7	-1.6	1.7	-1.9	0.1	1.7	3.3