[Hub]/) : Traits : Ulcerative Colitis (UC) :

chr16:27,691,641-29,595,483

Best TWAS P=6.49e-08 · Best GWAS P=4.24e-07 conditioned to 0.854

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CCDC101 0.09 0.00 enet 7 0.01 1.1e-01 5.1 -5.1 2.8e-07 -0.93 0.01 0.95 FALSE
2 GTEx Artery Coronary SH2B1 0.10 0.09 lasso 6 0.03 4.5e-02 5.1 -5.3 1.5e-07 -0.98 0.02 0.59 FALSE
3 GTEx Artery Coronary RP11-1348G14.4 0.12 0.11 lasso 2 0.09 7.6e-04 5.1 -5.2 1.6e-07 -0.97 0.02 0.94 FALSE
4 GTEx Artery Tibial EIF3CL 0.05 0.03 lasso 2 0.04 8.3e-04 4.6 5.2 1.8e-07 0.77 0.08 0.86 FALSE
5 GTEx Cells Transformed fibroblasts SULT1A1 0.05 0.05 enet 9 0.04 4.5e-04 4.5 -5.3 9.9e-08 -0.79 0.06 0.92 FALSE
6 GTEx Colon Transverse NFATC2IP 0.07 0.08 lasso 6 0.09 3.5e-05 4.5 5.3 1.5e-07 0.73 0.07 0.89 FALSE
7 GTEx Esophagus Muscularis CCDC101 0.07 0.07 enet 5 0.04 2.2e-03 5.0 -5.3 1.0e-07 -0.97 0.01 0.93 FALSE
8 GTEx Esophagus Muscularis SULT1A1 0.10 0.09 enet 16 0.08 1.0e-05 5.1 -5.4 8.6e-08 -0.94 0.02 0.98 FALSE
9 GTEx Heart Atrial Appendage SULT1A1 0.14 0.08 enet 13 0.09 5.5e-05 5.1 -5.4 6.5e-08 -0.92 0.02 0.97 TRUE
10 GTEx Lung SULT1A1 0.07 0.09 lasso 3 0.07 8.6e-06 5.0 -5.1 3.0e-07 -0.97 0.01 0.99 FALSE
11 GTEx Muscle Skeletal CCDC101 0.12 0.08 enet 7 0.10 9.9e-10 5.1 -5.2 1.9e-07 -0.93 0.01 0.99 FALSE
12 GTEx Muscle Skeletal SULT1A1 0.10 0.04 enet 20 0.05 7.5e-06 4.6 -5.4 6.8e-08 -0.80 0.03 0.96 FALSE
13 GTEx Pancreas SULT1A1 0.12 0.13 enet 13 0.11 2.1e-05 4.9 -5.4 6.8e-08 -0.86 0.02 0.97 FALSE
14 GTEx Stomach EIF3C 0.11 0.07 enet 12 0.06 8.6e-04 3.1 5.2 2.4e-07 0.71 0.13 0.70 FALSE
15 GTEx Stomach EIF3CL 0.09 0.06 lasso 3 0.12 2.5e-06 -4.4 5.1 3.0e-07 0.74 0.10 0.83 FALSE
16 ROSMAP Brain Pre-frontal Cortex RP11-1348G14.1 0.03 0.01 blup 175 0.02 3.6e-03 -4.2 -5.1 2.8e-07 -0.86 0.04 0.89 FALSE
17 The Cancer Genome Atlas Colon Adenocarcinoma EIF3C 0.09 0.03 blup 10 0.03 8.6e-03 -4.0 5.2 2.1e-07 0.70 0.01 0.71 FALSE
18 The Cancer Genome Atlas Brain Lower Grade Glioma NUPR1 0.03 0.03 lasso 4 0.04 4.8e-05 5.1 5.2 1.8e-07 0.96 0.01 0.98 FALSE
19 The Cancer Genome Atlas Prostate Adenocarcinoma CCDC101 0.06 0.08 lasso 4 0.07 6.4e-08 5.1 -5.1 2.9e-07 -0.98 0.00 1.00 FALSE