Best TWAS P=1.45e-08 · Best GWAS P=3.76e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Hypothalamus | ZFP90 | 0.17 | 0.13 | lasso | 7 | 0.09 | 5.0e-03 | -5.5 | -5.3 | 1.2e-07 | 0.98 | 0.02 | 0.92 | FALSE |
| 2 | GTEx | Muscle Skeletal | ZFP90 | 0.07 | 0.06 | lasso | 10 | 0.04 | 4.6e-05 | -5.4 | 5.4 | 8.6e-08 | -0.99 | 0.01 | 0.98 | FALSE |
| 3 | GTEx | Spleen | ZFP90 | 0.31 | 0.25 | lasso | 9 | 0.22 | 3.0e-06 | -5.4 | 5.3 | 9.2e-08 | -0.94 | 0.01 | 0.98 | FALSE |
| 4 | GTEx | Testis | ZFP90 | 0.14 | 0.14 | lasso | 5 | 0.11 | 1.0e-05 | -5.2 | -5.5 | 3.4e-08 | 0.98 | 0.02 | 0.98 | FALSE |
| 5 | GTEx | Whole Blood | ZFP90 | 0.13 | 0.09 | lasso | 5 | 0.14 | 5.6e-13 | -5.5 | 5.3 | 1.1e-07 | -0.90 | 0.01 | 0.99 | FALSE |
| 6 | METSIM | Adipose | ZFP90 | 0.09 | 0.06 | lasso | 7 | 0.07 | 3.0e-11 | -5.4 | 5.4 | 5.6e-08 | -0.98 | 0.01 | 0.99 | FALSE |
| 7 | NTR | Blood | ZFP90 | 0.07 | 0.07 | enet | 14 | 0.07 | 9.4e-22 | -5.5 | 5.7 | 1.5e-08 | -0.98 | 0.01 | 0.99 | TRUE |
| 8 | YFS | Blood | ZFP90 | 0.43 | 0.46 | enet | 35 | 0.48 | 2.1e-184 | -5.4 | 5.5 | 3.7e-08 | -0.96 | 0.01 | 0.99 | FALSE |