Hub : Genes

ZFP90

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0720	0.0260	9.8e-07	0.047	0.053	0.039	0.054	0.050	2.1e-06	4.8e-07	1.5e-05	3.3e-07	9.4e-07
2	GTEx	Brain Caudate basal ganglia	0.1060	0.0560	8.4e-03	0.059	NA	0.049	NA	0.024	8.7e-03	NA	1.5e-02	NA	6.6e-02
3	GTEx	Brain Cortex	0.1960	0.0830	4.0e-04	0.095	NA	0.073	NA	0.127	1.4e-03	NA	4.6e-03	NA	2.3e-04
4	GTEx	Brain Hypothalamus	0.1650	0.0730	1.7e-03	0.134	NA	0.024	NA	0.085	4.9e-04	NA	9.0e-02	NA	5.0e-03
5	GTEx	Cells Transformed fibroblasts	0.1210	0.0570	2.2e-03	0.047	NA	0.045	NA	0.043	2.0e-04	NA	2.7e-04	NA	3.6e-04
6	GTEx	Lung	0.1140	0.0463	1.6e-04	0.069	NA	0.060	NA	0.039	5.9e-06	NA	2.4e-05	NA	5.3e-04
7	GTEx	Muscle Skeletal	0.0665	0.0290	8.0e-04	0.058	NA	0.041	NA	0.043	2.4e-06	NA	6.7e-05	NA	4.6e-05
8	GTEx	Spleen	0.3080	0.1070	7.7e-05	0.250	NA	0.192	NA	0.216	4.2e-07	NA	1.1e-05	NA	3.0e-06
9	GTEx	Testis	0.1360	0.0530	4.6e-05	0.139	NA	0.108	NA	0.113	9.9e-07	NA	1.6e-05	NA	1.0e-05
10	GTEx	Whole Blood	0.1270	0.0400	1.3e-07	0.093	NA	0.138	NA	0.141	6.0e-09	NA	1.0e-12	NA	5.6e-13
11	METSIM	Adipose	0.0920	0.0292	6.4e-08	0.065	0.056	0.071	0.064	0.074	5.6e-10	7.1e-09	7.9e-11	7.8e-10	3.0e-11
12	NTR	Blood	0.0748	0.0230	5.0e-16	0.069	0.056	0.071	0.068	0.069	3.1e-21	1.5e-17	9.4e-22	5.0e-21	3.1e-21
13	YFS	Blood	0.4313	0.0437	0.0e+00	0.464	0.477	0.485	0.484	0.483	2.1e-173	5.6e-180	2.1e-184	1.2e-183	3.5e-183
14	TCGA	Glioblastoma Multiforme	0.0970	0.0520	1.2e-03	0.081	0.095	0.090	NA	0.077	1.9e-03	8.3e-04	1.1e-03	NA	2.4e-03
15	TCGA	Brain Lower Grade Glioma	0.0972	0.0366	3.3e-14	0.160	0.140	0.141	NA	0.158	8.5e-18	1.3e-15	8.9e-16	NA	1.5e-17

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Bipolar Disorder (2018)	0.7	1.1	2.3	-1.1	-0.5	-1.5	-1.2	-1.0	0.3	1.1	0.9	-1.0	1.5	0.8	1.1	0.8	-1.2	-1.4
Bipolar Disorder or Schizophrenia	1.1	2.8	6.7	-2.6	-1.2	-1.4	-1.3	-1.3	-0.4	1.5	1.7	-1.5	2.2	1.4	1.4	1.3	-2.1	-2.5
Depressed Affect (Nagel 2018)	0.6	1.3	3.5	0.0	0.7	1.9	1.7	1.5	-0.8	-1.5	-1.0	1.3	-1.0	-1.3	-1.3	-0.9	0.6	0.1
Depression (Nagel 2018)	0.6	1.0	2.2	-0.5	0.8	1.4	1.5	1.1	-1.0	-1.2	-0.7	1.1	-0.7	-1.3	-1.0	-0.8	0.4	0.0
Intelligence (Savage-Jansen 2018)	0.7	2.1	8.5	2.9	2.1	0.5	0.8	0.7	0.2	-1.4	-2.5	1.3	-0.8	-1.5	-1.2	-1.5	1.1	0.2
Neuroticism (Nagel 2018)	0.3	0.7	2.6	-0.5	0.7	1.6	1.2	1.3	-0.6	-0.9	-0.2	0.7	-0.7	-1.0	-0.7	-0.3	0.3	0.2
Schizophrenia (2018)	0.9	1.8	6.1	-2.5	-1.2	-0.6	-0.7	-0.9	-0.7	1.0	1.5	-1.1	1.6	1.2	0.9	1.0	-1.8	-2.1
Schizophrenia vs Biploar Disorder	3.8	5.0	11.9	1.3	1.1	3.5	2.8	2.7	-1.9	-2.4	-1.7	2.3	-2.3	-2.2	-2.3	-2.3	1.9	1.4
Worry (Nagel 2018)	0.2	0.4	2.8	0.0	1.7	1.1	0.7	0.8	0.0	-0.5	0.1	0.3	-0.4	-0.6	-0.2	0.1	0.2	0.2
Alzheimer’s Disease (in mother)	0.9	1.1	2.2	-1.5	-1.2	-0.5	-0.8	-0.6	1.2	0.9	1.1	-0.7	1.2	0.7	0.9	1.0	-1.1	-1.3
Alzheimer’s Disease (in father)	0.8	0.8	2.0	0.7	0.8	0.9	0.9	1.2	-0.3	-0.8	-0.6	0.7	-1.3	-0.8	-0.7	-0.7	1.2	1.4
Alzheimer’s Disease (including proxy)	0.3	0.4	1.3	-1.2	-0.7	-0.3	-0.3	-0.4	0.9	0.6	0.9	-0.5	0.5	0.4	0.7	0.8	-0.5	-0.4
Crohns Disease (2017)	0.4	0.8	1.7	0.3	-0.4	-1.3	-1.1	-1.2	0.8	1.1	0.6	-1.0	0.6	1.2	0.8	1.0	-0.5	-0.1
Irritable Bowel Disease (IBD)	6.3	15.0	20.6	-2.9	-2.7	-4.0	-4.3	-3.7	3.2	4.3	4.0	-4.3	4.1	4.4	4.3	4.5	-3.8	-2.9
Ulcerative Colitis (UC)	13.1	24.5	32.1	-4.5	-3.3	-5.0	-5.3	-4.5	3.8	5.4	5.3	-5.5	5.3	5.4	5.7	5.5	-5.0	-3.9
Major Depression (MDD)	1.0	1.2	2.1	0.5	1.3	0.9	1.2	1.1	-1.4	-1.3	-1.4	1.3	-0.6	-1.4	-1.2	-1.2	0.5	-0.2
Reaction Time	1.8	3.4	5.3	1.6	2.1	1.1	1.9	1.7	-1.5	-1.8	-2.3	1.9	-2.0	-1.8	-1.8	-1.9	2.0	1.7
Verbal and Numeric Reasoning (VNR)	0.6	1.5	4.3	2.1	0.4	0.8	1.0	0.9	-0.1	-1.6	-2.1	1.5	-0.6	-1.4	-1.4	-1.5	0.6	-0.5
Breast Cancer	1.1	2.7	4.8	2.1	0.9	2.2	1.5	2.1	-0.3	-1.8	-1.5	1.8	-1.6	-1.9	-1.7	-1.3	1.6	1.1
Ovarian Cancer	1.0	1.3	2.5	-0.7	-1.6	-1.2	-1.2	-0.9	1.4	0.9	1.0	-1.0	1.1	0.9	1.1	1.4	-1.0	-1.0
Prostate Cancer	4.1	5.8	11.0	-1.9	-2.0	-2.0	-2.4	-2.6	1.9	2.1	1.8	-2.2	3.1	2.3	2.1	2.4	-3.1	-3.3
Age at First Birth	0.3	0.4	0.7	0.8	0.3	-0.6	0.2	-0.4	-0.8	-0.4	-0.8	0.5	-0.7	-0.4	-0.3	-0.8	0.8	0.8
Bipolar Disorder (2011)	0.3	0.3	2.0	-0.2	0.5	-1.4	-0.6	-0.9	-0.9	0.5	-0.0	-0.5	0.2	0.4	0.3	-0.1	-0.1	0.2
Body Mass Index (BMI) (2010)	2.1	2.9	4.7	1.2	1.3	1.4	1.7	1.3	-2.2	-1.5	-2.1	1.5	-2.0	-1.5	-1.8	-1.7	1.9	1.9
Coronary Artery Disease (CAD)	0.1	0.1	0.6	0.8	0.2	-0.1	-0.2	0.1	-0.5	-0.1	-0.5	0.1	0.4	-0.2	-0.1	0.0	-0.2	-0.7
Crohns Disease (2012)	2.8	4.4	6.1	-1.6	-2.3	-2.5	-2.3	-2.1	1.4	2.3	1.9	-2.2	2.2	2.4	2.1	2.1	-2.1	-1.7
Mean Putamen Volume	2.2	2.5	4.1	-1.4	-0.2	-1.2	-1.4	-1.5	1.0	1.5	1.6	-1.7	1.8	2.0	1.7	2.0	-2.0	-1.9
Fasting Glucose	0.6	0.7	1.5	1.2	-1.2	-0.1	0.4	0.3	1.0	-0.7	-0.5	0.4	-1.1	-0.4	-0.9	-0.8	0.8	1.2
HbA1C	2.9	3.2	8.0	2.2	1.7	1.1	1.3	1.4	-1.5	-1.3	-1.8	1.4	-2.3	-1.6	-1.3	-1.9	2.5	2.8
HDL Cholesterol	0.9	1.4	12.2	-3.5	0.8	0.0	0.2	-0.5	-1.0	0.9	1.0	-0.9	1.0	0.8	1.0	0.7	-0.9	-0.8
LDL Cholesterol	0.3	0.5	1.0	0.5	1.0	0.7	0.7	0.5	-0.3	-0.7	-0.4	0.7	-0.9	-0.7	-0.5	-0.4	0.9	0.9
Lupus	3.6	5.4	8.9	1.1	2.1	2.4	3.0	2.1	-2.3	-2.7	-2.2	2.7	-2.4	-2.6	-2.5	-2.5	2.1	1.4
Neuroticism (2016)	0.3	0.4	2.2	-1.5	-0.5	-0.6	-0.1	-0.2	0.1	0.4	0.7	-0.4	0.5	0.4	0.5	0.6	-0.7	-0.6
Primary Biliary Cirrhosis	1.0	1.5	7.3	-2.7	-0.8	-0.7	-0.4	-0.7	-0.4	0.8	1.1	-0.9	1.5	0.8	0.8	0.9	-1.6	-1.9
Rheumatoid Arthritis	0.7	1.0	2.0	0.8	0.4	0.6	0.9	0.9	-1.4	-1.2	-1.1	1.1	-1.0	-1.2	-1.0	-1.0	0.9	0.7
Schizophrenia (2014)	1.1	2.5	6.7	-2.6	-1.6	-0.9	-0.9	-1.1	-0.4	1.2	1.8	-1.5	1.9	1.4	1.2	1.2	-2.1	-2.3
Triglycerides	0.3	0.6	1.6	0.8	0.9	0.4	0.4	0.2	-1.2	-0.5	-0.7	0.5	-1.0	-0.5	-0.4	-0.6	0.9	1.3
Type 2 Diabetes (T2D) (2012)	3.0	3.4	8.9	-0.5	0.2	-0.8	-2.0	-0.4	2.4	1.9	1.5	-1.7	2.7	1.5	1.7	2.3	-2.3	-3.0
Ulcerative Colitis	11.9	17.3	22.7	-3.7	-3.1	-4.0	-4.4	-3.5	3.5	4.4	4.2	-4.5	4.6	4.6	4.8	4.7	-4.4	-3.7
Blood Eosinophil Count	14.0	107.7	132.2	-10.8	-9.2	-9.0	-10.1	-9.3	7.9	10.5	11.3	-10.8	11.3	10.9	11.5	11.4	-11.4	-9.4
Blood Platelet Count	3.3	38.1	45.6	4.3	3.8	6.4	6.7	6.5	-6.0	-6.4	-6.2	6.8	-6.8	-6.7	-6.7	-6.3	6.5	5.6
Blood Red Count	1.6	15.2	44.6	1.6	6.7	4.1	4.2	3.7	-4.7	-3.2	-4.5	3.4	-3.2	-3.8	-3.5	-3.8	3.4	2.3
Blood White Count	1.0	7.3	11.0	-2.9	-2.4	-1.9	-2.6	-2.6	2.1	2.6	2.5	-2.8	3.0	2.6	3.3	3.0	-3.2	-2.6
Heel T-Score	0.4	2.8	21.6	-0.5	-0.4	-0.5	1.5	0.6	-4.7	-1.6	-1.2	1.4	-1.4	-1.3	-0.9	-2.1	1.3	0.9
BMI	0.1	0.9	5.2	0.9	1.0	0.3	0.7	0.3	-0.7	-0.9	-2.3	0.8	-0.3	-0.7	-0.8	-1.2	0.6	-0.2
Height	0.4	8.3	12.7	2.1	2.3	2.2	3.0	3.6	-1.9	-2.7	-3.5	3.0	-3.1	-2.8	-3.1	-3.0	3.4	3.0
Waist Hip Ratio (WHR)	3.2	14.2	22.7	-4.1	-4.8	-2.8	-3.3	-2.8	3.6	3.4	4.0	-3.5	4.0	3.5	3.6	4.4	-4.4	-3.7
Systolic Blood Pressure	0.1	0.4	2.7	0.9	1.6	-0.6	-0.6	-0.8	-0.3	0.3	-0.6	-0.3	0.2	0.2	0.4	0.2	-0.0	0.2
Smoking Status	2.0	4.7	10.4	-3.2	-2.7	-2.3	-2.0	-1.2	1.8	2.1	2.3	-2.2	2.0	2.5	2.0	2.0	-2.0	-1.4
Allergy or Eczema	6.5	17.2	24.1	-2.7	-3.6	-4.6	-4.9	-4.4	3.5	4.5	4.5	-4.7	4.0	4.6	4.8	4.3	-3.8	-2.4
Cardiovascular Disease	0.3	0.8	2.4	-0.9	-0.2	-1.1	-0.9	-1.5	0.6	1.0	0.4	-1.2	0.7	1.1	1.2	0.9	-0.8	-0.4
Hypothyroidism (self reported)	4.7	10.9	18.5	-4.3	-2.3	-3.1	-3.2	-3.6	1.2	3.5	3.5	-3.4	3.7	3.4	3.2	3.3	-3.7	-3.1
Respiratory disease	2.1	4.7	7.1	-1.1	-1.9	-2.0	-2.6	-2.5	2.7	2.2	2.6	-2.3	1.9	2.2	2.6	2.2	-1.9	-1.0
Type 2 Diabetes (T2D) (2018)	0.5	1.0	1.7	-0.7	0.3	-0.6	-1.0	-0.8	1.2	1.0	0.7	-1.0	1.3	1.0	1.1	1.3	-1.2	-1.3
Lung FEV1/FVC ratio	2.0	10.4	24.3	0.6	3.2	3.1	3.9	3.2	-4.9	-3.4	-3.0	3.2	-2.9	-3.2	-3.7	-3.6	2.7	1.6
Lung FVC	0.9	4.8	11.0	-0.7	-1.4	-3.2	-2.8	-3.3	2.1	2.4	1.7	-2.5	1.7	2.5	2.4	1.9	-1.5	-0.5
Neuroticism	0.9	2.3	4.7	0.5	1.6	2.2	2.0	1.7	-1.6	-1.7	-1.3	1.6	-1.4	-1.8	-1.4	-1.1	1.0	0.6
Chronotype (morning person)	0.7	1.5	6.0	1.9	0.9	-0.2	0.5	0.2	-0.9	-0.7	-1.4	0.8	-1.7	-0.6	-0.7	-1.4	1.8	2.5
Hair Pigment	0.0	0.4	1.1	0.3	0.4	0.9	0.8	-0.1	-0.6	-0.3	-1.1	0.3	-0.7	-0.4	-0.7	-0.5	0.5	0.7
Tanning	0.1	1.8	4.6	-1.7	-1.7	-2.1	-1.3	-0.7	0.9	1.4	1.6	-1.5	1.0	1.8	1.4	0.6	-0.5	-0.3
Hand grip strength (left)	0.4	1.0	2.6	0.8	-1.0	1.3	1.1	1.6	-0.6	-1.1	-0.7	1.3	-0.7	-1.1	-1.3	-0.7	0.6	0.2
Number of treatments/medications taken	1.8	3.3	7.7	-2.8	-0.7	-2.1	-1.6	-2.5	-0.0	1.8	1.6	-2.0	1.6	2.2	2.1	1.7	-1.7	-1.0
Average weekly spirits intake	1.7	2.1	10.8	-0.6	-1.8	-0.7	-1.2	-1.0	3.3	1.1	1.4	-1.2	1.3	1.2	1.1	1.3	-1.4	-1.4
Sensitivity / hurt feelings	0.7	1.2	3.5	0.8	0.8	1.9	1.3	1.7	-0.2	-0.9	-1.0	1.1	-1.0	-1.2	-1.2	-0.7	0.9	0.8
Frequency of depressed mood in last 2 weeks	0.4	0.5	2.2	-0.4	0.6	0.6	0.8	0.3	-1.5	-0.7	-0.5	0.6	-0.8	-0.6	-0.4	-0.8	0.6	0.8
Hearing difficulty/problems: Yes	0.3	0.5	1.2	1.1	0.2	1.1	0.7	0.8	0.3	-0.9	-0.6	1.0	-0.3	-0.8	-0.7	-0.2	0.2	-0.5
Relative age of first facial hair	0.2	0.4	1.1	0.6	0.4	1.0	0.6	0.4	-0.4	-0.6	-0.9	0.7	-0.7	-0.7	-0.6	-0.5	0.7	0.6
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.8	-0.3	0.4	-0.8	-0.8	-0.5	0.4	0.8	0.5	-0.8	0.2	0.5	0.9	0.5	-0.0	0.6
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.5	-0.3	-0.4	0.0	0.7	0.5	-0.7	-0.4	0.0	0.2	-0.7	-0.1	-0.5	-0.3	0.4	0.6
Ever had hysterectomy (womb removed)	0.6	0.6	1.8	-1.2	-1.4	-0.8	-0.5	-0.4	0.4	0.8	0.9	-0.8	0.8	0.7	0.5	0.6	-0.8	-0.8
Systolic blood pressure, automated reading	0.3	0.8	1.6	0.4	1.3	-1.3	-1.2	-1.2	1.0	1.1	0.1	-1.2	0.5	1.0	1.0	0.6	-0.1	0.4
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	1.8	-0.4	-0.4	-1.0	-1.3	-1.0	0.6	1.3	0.8	-1.3	0.7	1.3	1.1	1.0	-0.5	0.1
Angina	0.2	0.3	1.3	-1.1	-1.1	-0.8	-0.1	-0.0	-0.4	0.2	0.7	-0.3	0.3	0.2	0.0	0.2	-0.3	-0.4
Medication for hormone replacement therapy	0.6	0.7	1.4	-0.9	-1.0	-0.2	-0.8	-0.6	1.2	0.8	1.0	-0.8	0.7	0.9	0.7	0.9	-0.8	-0.4
Vitamin and mineral supplements	0.6	0.8	4.0	0.3	0.5	-0.1	-0.6	-0.2	2.0	0.4	-0.4	-0.5	1.2	0.3	0.7	1.1	-1.0	-1.7
Supplements: Zinc	0.2	0.2	1.2	-0.3	0.7	-0.2	0.3	0.0	-1.1	-0.2	0.1	0.2	-0.5	-0.1	-0.2	-0.3	0.5	0.8
Medication: Co-codamol	0.9	1.0	2.1	0.1	0.8	1.1	1.5	1.4	-0.5	-1.3	-1.1	1.0	-0.9	-1.1	-1.0	-1.2	0.8	0.2
Medication: Metformin	1.4	1.9	3.3	-1.2	1.0	-1.5	-1.4	-1.8	1.3	1.4	1.0	-1.4	1.5	1.4	1.5	1.4	-1.4	-1.3
Diabetes (father)	0.1	0.1	0.6	0.2	0.8	0.2	0.1	0.2	0.2	0.1	-0.2	-0.2	0.1	0.0	0.2	-0.3	-0.1	-0.1
Diabetes (mother)	0.9	1.1	2.5	0.1	1.5	1.1	1.3	1.6	-1.0	-1.1	-0.6	1.1	-1.1	-0.8	-1.1	-1.0	1.0	0.8
Severe depression (siblings)	0.4	0.4	3.2	0.3	-0.3	1.8	0.8	0.8	-0.2	-0.7	-0.2	0.6	-0.2	-0.8	-0.3	-0.1	-0.2	-0.5
Pack years adult smoking proportion	0.2	0.3	1.1	0.5	0.8	1.0	0.6	0.0	0.6	-0.6	-0.6	0.6	0.1	-0.4	-0.3	0.0	-0.3	-0.9
Impedance of leg (right)	1.2	5.9	13.6	-3.7	-1.5	-1.9	-2.4	-2.2	0.6	2.8	3.4	-2.6	2.1	2.4	2.5	3.1	-2.1	-0.9
Leg fat-free mass (left)	0.4	2.2	7.1	1.7	0.6	0.7	1.5	1.3	-0.5	-1.7	-2.7	1.8	-1.1	-1.4	-1.7	-2.1	1.3	0.2
Trunk fat percentage	0.2	0.7	2.8	-1.7	0.4	-0.6	-0.5	-1.0	-0.3	0.8	-0.0	-0.7	1.0	0.8	0.7	0.7	-0.8	-0.9
Hand grip strength (right)	0.2	0.4	1.6	0.6	0.1	1.1	0.6	1.3	0.2	-0.7	-0.6	0.9	-0.1	-0.6	-0.9	-0.2	0.1	-0.5
Townsend deprivation index at recruitment	1.5	2.1	3.8	-1.0	-0.7	-1.4	-1.6	-1.9	1.1	1.4	1.5	-1.4	1.8	1.3	1.5	1.4	-1.7	-1.7
Current tobacco smoking	0.3	0.5	1.9	-1.4	-1.4	-0.5	-0.2	-0.0	0.7	0.3	0.2	-0.4	0.7	0.6	0.2	0.4	-0.9	-1.0
Average weekly fortified wine intake	0.3	0.3	1.1	0.4	-0.2	-0.4	-0.6	-0.3	0.7	0.7	1.0	-0.6	0.2	0.6	0.4	0.7	-0.4	0.1
Maternal smoking around birth	1.9	2.8	4.8	-1.6	-1.9	-1.8	-1.5	-2.2	1.3	1.6	1.4	-1.7	1.7	1.8	1.6	1.6	-1.8	-1.6
Fed-up feelings	0.3	0.5	1.7	-0.1	0.3	1.2	1.0	1.3	-0.2	-0.8	-0.5	0.7	-0.5	-0.6	-0.9	-0.3	0.2	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.7	-1.3	-0.1	0.6	0.7	0.6	-0.1	-0.4	0.1	0.2	0.1	-0.4	-0.2	0.1	-0.4	-0.6
Relative age voice broke	0.9	1.3	2.3	1.5	1.3	1.4	0.9	1.2	-0.3	-0.9	-1.5	1.1	-1.2	-0.9	-1.0	-1.1	1.3	1.1
Taking other prescription medications	2.7	4.2	8.3	-2.9	-1.8	-2.0	-1.7	-1.9	1.1	1.9	2.4	-2.0	2.1	2.0	2.1	2.2	-2.3	-2.0
Age when periods started (menarche)	0.4	1.1	2.3	1.5	1.1	1.5	0.9	1.2	0.2	-0.8	-0.8	1.0	-1.0	-1.0	-1.1	-1.0	0.9	0.9
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.4	0.2	-0.2	0.8	0.8	0.5	-0.7	-0.6	-0.9	0.8	-0.9	-0.5	-1.0	-1.2	0.9	1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.8	5.4	0.2	-0.3	-0.2	0.7	0.5	-2.3	-0.8	-1.0	0.8	-0.7	-0.6	-0.5	-1.2	0.7	0.4
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	1.5	-0.3	-0.5	-0.3	-0.9	-0.5	-0.1	1.0	1.1	-0.9	0.1	0.6	1.2	0.8	0.0	1.1
Qualifications: CSEs or equivalent	0.3	0.4	0.7	-0.8	-0.6	-0.7	-0.7	-0.7	0.1	0.7	0.8	-0.7	0.6	0.8	0.5	0.6	-0.6	-0.4
Serious illness, injury or assault to yourself	0.1	0.2	1.0	-0.2	-1.0	-0.1	0.1	0.7	0.7	-0.1	-0.0	0.0	-0.2	-0.1	0.1	-0.2	0.2	0.2
High blood pressure	0.1	0.4	1.3	0.4	0.4	-0.7	-0.5	-0.8	1.2	0.7	0.2	-0.9	0.2	0.9	0.7	0.5	-0.2	0.3
Hayfever, allergic rhinitis or eczema	5.7	12.3	15.6	-2.7	-3.2	-3.9	-4.0	-3.7	2.9	3.6	3.5	-3.8	3.6	3.8	3.9	3.6	-3.5	-2.7
Multivitamins +/- minerals	1.0	1.3	6.4	-0.2	-0.1	0.2	0.9	0.2	-2.5	-0.7	-0.1	0.8	-1.4	-0.7	-0.9	-1.5	1.4	1.9
Stomach or abdominal pain in last month	1.8	2.3	5.8	0.1	1.3	0.8	1.4	1.4	-2.0	-1.1	-1.2	1.4	-2.0	-1.2	-1.3	-1.4	2.1	2.4
Supplements: Glucosamine	0.6	0.8	3.2	-0.3	-0.7	-1.6	-0.9	-1.8	0.1	0.9	0.6	-1.0	0.5	1.1	0.9	0.5	-0.4	0.0
Diverticular disease/diverticulitis (self-reported)	1.2	1.5	2.5	1.5	0.8	1.6	1.2	1.4	0.0	-1.4	-0.9	1.4	-1.2	-1.5	-1.3	-1.2	1.0	0.9
Medication: Atenolol	0.4	0.5	3.3	0.3	1.8	-0.1	0.3	0.2	-0.4	-0.1	-0.8	-0.0	-0.7	0.3	-0.2	-0.7	0.9	1.2
Medication: Levothyroxine sodium	0.9	1.5	2.8	-1.7	-1.2	-1.3	-1.1	-1.2	-0.1	1.1	1.6	-1.1	1.4	1.0	1.0	1.0	-1.4	-1.3
Sitting height	0.0	0.3	1.4	-0.1	0.4	-1.2	-0.4	-0.7	-0.9	0.5	-0.4	-0.2	-0.2	0.3	0.2	-0.3	0.5	1.0
Chronic bronchitis/emphysema (father)	2.3	2.7	4.5	-1.5	-2.1	-1.9	-1.6	-2.0	0.4	1.8	1.5	-1.8	1.4	1.8	2.1	1.5	-1.4	-0.8
High blood pressure (mother)	0.1	0.2	0.5	0.2	0.4	0.7	0.6	0.4	-0.6	-0.5	-0.3	0.5	-0.3	-0.5	-0.3	-0.3	0.2	0.0
Body mass index (BMI)	0.2	1.0	4.3	1.0	1.0	0.7	1.0	0.5	-0.5	-1.1	-2.1	1.0	-0.6	-0.9	-1.0	-1.3	0.8	0.0
Impedance of leg (left)	0.7	3.4	9.5	-3.1	-0.6	-1.0	-1.7	-1.6	0.1	2.3	2.8	-2.0	1.4	1.8	2.0	2.6	-1.4	-0.1
Leg predicted mass (left)	0.4	2.1	6.9	1.6	0.5	0.7	1.5	1.2	-0.5	-1.7	-2.6	1.7	-1.0	-1.4	-1.7	-2.0	1.2	0.2
Trunk fat mass	0.0	0.2	1.3	-0.6	0.7	-0.0	0.3	-0.2	-0.7	-0.1	-1.1	0.2	0.2	-0.1	-0.2	-0.3	0.0	-0.5
Waist circumference	0.1	0.2	1.4	-0.0	0.3	-0.1	0.1	-0.3	0.5	-0.1	-1.1	0.1	0.6	0.0	-0.1	-0.0	-0.4	-1.2
Number of incorrect matches in round	0.4	0.6	3.4	0.5	0.8	0.7	0.6	0.7	-0.6	-0.3	0.2	0.5	-1.2	-0.6	-0.3	-0.5	1.1	1.9
Past tobacco smoking	1.1	2.1	4.2	2.1	2.0	1.2	1.3	1.0	-1.1	-1.3	-2.0	1.2	-1.4	-1.5	-1.3	-1.3	1.4	1.1
Alcohol usually taken with meals	0.2	0.4	3.1	-0.6	0.6	-0.6	0.2	-0.1	-1.8	-0.1	-0.4	0.1	-0.4	-0.0	0.1	-0.5	0.4	0.6
Nervous feelings	0.2	0.3	1.3	0.1	1.1	0.3	-0.2	0.8	0.9	0.3	0.9	-0.5	-0.1	0.3	0.4	0.7	-0.1	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	2.6	-1.5	-0.2	0.6	1.0	0.8	-1.6	-0.7	-0.2	0.5	-0.3	-0.7	-0.4	-0.2	0.0	-0.1
Hearing difficulty/problems with background noise	0.4	0.6	1.7	0.8	1.2	1.3	0.8	0.8	-0.1	-0.9	-0.7	0.9	-0.3	-1.1	-0.6	-0.3	0.3	-0.3
Hair/balding pattern: Pattern 2	0.8	1.1	2.4	0.5	0.8	1.3	1.0	0.8	-1.6	-1.0	-1.2	1.2	-0.7	-1.2	-1.2	-1.1	0.7	0.4
Had menopause	0.2	0.3	1.0	-0.6	0.6	-0.9	-0.0	-0.4	0.2	0.1	0.4	-0.5	0.5	0.4	0.1	0.4	-0.7	-1.0
Had other major operations	0.3	0.4	1.1	-1.1	-0.8	-0.7	-0.6	-0.4	-0.2	0.7	0.9	-0.6	0.2	0.7	0.4	0.3	-0.2	0.4
Forced vital capacity (FVC)	0.4	1.6	5.3	0.1	-0.9	-2.3	-1.8	-1.7	1.4	1.6	0.7	-1.4	0.5	1.3	1.3	0.9	-0.0	1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	7.2	0.2	-0.5	-0.3	0.9	0.2	-2.7	-1.0	-1.0	0.8	-0.8	-0.7	-0.6	-1.2	0.6	0.3
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.7	-0.3	0.7	0.5	0.4	0.4	-0.3	-0.2	-0.0	0.2	-0.5	-0.4	-0.0	-0.3	0.5	0.9
Qualifications: None of the above	0.7	1.4	4.0	-0.8	-1.0	-0.8	-1.1	-0.5	1.8	1.2	2.0	-1.3	0.8	1.4	1.1	1.6	-1.0	-0.2
Financial difficulties in last 2 years	0.1	0.2	0.4	-0.3	-0.2	0.2	0.6	-0.5	-0.5	-0.6	-0.4	0.4	-0.4	-0.4	-0.3	-0.6	0.1	0.1
Mouth/teeth dental problems	0.7	1.1	2.0	-0.6	-0.8	-1.4	-1.3	-1.3	0.7	1.4	0.8	-1.3	1.1	1.0	1.3	1.1	-1.0	-0.5
Heart attack	0.1	0.2	0.9	-0.6	0.5	-0.0	0.6	0.7	-0.9	-0.3	-0.3	0.3	-0.2	-0.3	-0.2	-0.0	0.1	-0.1
Allergy	6.8	15.7	19.1	3.3	3.6	4.1	4.4	4.0	-3.5	-4.1	-4.3	4.2	-4.1	-4.2	-4.3	-4.0	4.0	3.0
Pain all over the body in last month	0.2	0.2	0.7	-0.8	-0.1	-0.1	-0.2	-0.1	-0.1	0.3	0.4	-0.2	0.5	0.0	0.2	0.6	-0.5	-0.7
Diabetes (self-reported)	1.0	1.5	4.2	-0.7	0.5	-1.0	-1.2	-1.0	2.1	1.3	0.9	-1.3	1.3	1.4	1.3	1.3	-1.2	-1.0
Hayfever/allergic rhinitis (self-reported)	1.6	2.1	5.6	-1.5	-2.4	-0.9	-1.1	-0.8	1.4	1.0	1.9	-1.1	1.5	0.9	1.4	1.5	-1.7	-1.7
Medication: Ramipril	0.0	0.1	0.2	-0.4	0.3	0.2	0.2	0.2	-0.1	-0.1	-0.1	-0.1	0.1	0.2	-0.2	0.2	-0.3	-0.4
Medication: Simvastatin	1.7	2.5	5.1	-2.3	-1.1	-1.8	-1.2	-1.9	0.5	1.4	1.3	-1.6	1.8	1.7	1.6	1.2	-1.8	-1.8
Fluid intelligence score	0.7	1.4	4.3	2.1	0.4	0.7	1.0	0.6	-0.2	-1.4	-2.1	1.3	-0.7	-1.4	-1.2	-1.4	0.8	-0.1
Illnesses of siblings	0.2	0.3	1.1	-0.1	-0.3	-0.3	0.2	1.0	-0.8	-0.1	-0.1	0.3	-0.6	-0.0	-0.6	-0.2	0.7	1.0
Neuroticism score	0.4	0.8	2.0	0.2	0.9	1.4	1.3	1.3	-0.5	-1.1	-0.5	0.9	-0.9	-1.0	-0.9	-0.4	0.5	0.4
Weight	0.3	1.7	6.5	1.2	1.0	0.7	1.3	1.0	-0.7	-1.3	-2.5	1.4	-1.0	-1.1	-1.4	-1.7	1.3	0.5
Impedance of arm (right)	1.9	9.0	15.1	-3.9	-1.6	-2.4	-3.0	-2.7	1.1	3.6	3.8	-3.4	2.9	3.2	3.3	3.8	-2.8	-1.6
Arm fat percentage (right)	0.0	0.1	1.1	-0.2	0.6	0.1	0.1	-0.2	-0.5	0.0	-1.0	0.0	0.3	0.0	-0.1	-0.2	-0.1	-0.6
Trunk fat-free mass	0.8	4.7	10.9	2.6	1.0	1.3	2.2	2.1	-0.9	-2.4	-3.3	2.4	-2.0	-2.0	-2.5	-2.9	2.2	1.1
Hip circumference	0.1	0.4	2.3	0.6	1.1	-0.1	0.4	0.1	-0.1	-0.5	-1.5	0.5	-0.1	-0.4	-0.5	-0.7	0.4	-0.3
Time employed in main current job	0.2	0.2	1.0	-0.3	0.5	-0.9	0.2	-0.4	-0.2	0.1	0.4	-0.1	-0.6	0.1	-0.2	-0.2	0.7	1.0
Alcohol intake versus 10 years previously	0.2	0.2	0.8	-0.5	-0.0	-0.5	0.6	-0.2	-0.9	-0.5	-0.7	0.5	-0.3	-0.4	-0.4	-0.8	0.3	-0.0
Father’s age at death	0.2	0.2	1.3	-0.4	-0.0	-0.1	-0.2	-0.1	0.2	0.4	0.1	-0.4	0.8	0.2	0.1	0.4	-0.8	-1.2
Worrier / anxious feelings	0.8	1.6	2.9	1.2	1.7	1.7	1.6	1.4	-0.9	-1.4	-0.8	1.2	-1.3	-1.4	-1.2	-0.8	0.9	0.7
Frequency of tiredness / lethargy in last 2 weeks	2.5	4.1	11.4	-3.0	-3.4	-1.8	-1.3	-1.4	0.8	1.4	2.0	-1.7	2.1	1.4	1.8	1.7	-2.5	-2.4
Falls in the last year	0.4	0.5	2.3	0.2	-1.5	-0.6	-0.6	-0.9	1.5	0.5	0.4	-0.5	0.4	0.3	0.5	0.5	-0.4	-0.3
Hair/balding pattern: Pattern 3	0.2	0.3	1.0	0.8	0.1	-0.5	0.0	0.4	-0.0	-0.2	-0.5	0.2	-0.7	-0.1	-0.3	-0.6	0.9	1.0
Number of live births	0.6	0.8	2.0	0.4	-0.2	1.3	1.3	1.0	-0.3	-1.0	-0.6	0.9	-0.0	-0.9	-1.3	-0.6	-0.4	-1.4
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	2.0	0.4	-0.0	-1.0	-0.3	-0.5	-0.3	0.2	-0.3	-0.1	-0.6	0.1	-0.1	-0.4	0.8	1.4
Pulse rate	0.1	0.1	0.5	-0.7	0.1	-0.1	-0.3	-0.7	-0.5	0.3	-0.0	-0.3	0.2	0.2	0.3	0.2	-0.1	0.2
Happiness	4.7	5.7	9.7	1.9	1.8	3.1	2.8	2.7	-1.6	-2.7	-2.5	2.7	-2.2	-2.7	-2.8	-2.4	2.0	0.9
Noisy workplace	1.2	1.5	3.1	1.1	0.6	1.3	1.2	1.4	-1.4	-1.0	-0.5	1.3	-1.5	-1.2	-0.9	-1.0	1.6	1.8
Qualifications: A levels/AS levels or equivalent	0.1	0.1	0.6	0.8	0.6	0.3	0.1	-0.1	0.4	-0.2	-0.4	0.2	0.2	-0.3	-0.1	-0.1	-0.2	-0.7
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	2.2	-0.3	-1.0	-1.1	-1.3	-0.8	1.2	1.2	1.2	-1.1	1.1	0.9	1.5	1.1	-0.9	-0.6
Mouth/teeth dental problems: Dentures	1.0	1.7	2.6	-1.3	0.1	-0.6	-1.1	-1.4	1.3	1.2	1.5	-1.4	1.4	1.5	1.1	1.6	-1.6	-1.4
Asthma	0.8	1.5	2.4	-0.5	-1.5	-1.4	-1.4	-1.5	1.5	1.0	1.5	-1.1	1.1	1.1	1.2	1.0	-1.2	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	3.1	-1.6	-0.0	-1.0	-0.7	-1.8	-1.0	0.7	0.6	-0.8	0.7	0.9	0.9	0.8	-0.8	-0.4
Medication: Cholesterol lowering	1.7	2.7	4.8	-2.2	-0.8	-2.2	-1.4	-1.4	0.4	1.6	1.3	-1.8	1.8	1.8	1.9	1.6	-1.7	-1.6
Depression (self-reported)	2.2	2.6	3.7	-1.7	-1.5	-1.6	-1.5	-1.3	1.5	1.5	1.5	-1.7	1.8	1.5	1.8	1.7	-1.9	-1.7
Medication: Lansoprazole	0.4	0.5	1.2	-0.9	-0.0	-0.7	-0.5	-0.3	0.3	0.5	0.4	-0.6	0.9	0.4	0.6	0.6	-1.1	-1.1
Prospective memory result	0.9	1.1	2.1	0.2	0.9	0.7	1.3	1.2	-1.5	-1.1	-1.3	1.0	-1.0	-0.9	-1.2	-1.1	1.0	0.6
Lung cancer (father)	1.4	1.6	2.8	1.2	1.5	1.7	1.4	1.5	-1.1	-1.3	-1.3	1.3	-1.0	-1.4	-1.6	-1.2	1.0	0.4
Illnesses of mother	0.4	0.5	2.1	1.4	0.2	0.7	0.4	0.6	0.0	-0.6	-0.6	0.6	-0.7	-0.5	-0.8	-0.6	0.6	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	2.0	0.5	0.2	-0.8	-0.0	-0.4	-0.5	-0.0	-0.7	0.2	-0.8	-0.3	-0.5	-0.6	1.1	1.4
Pulse wave Arterial Stiffness index	0.2	0.2	1.5	-1.2	0.6	0.5	0.5	0.5	-0.5	-0.1	-0.1	0.1	0.1	0.0	-0.3	0.0	-0.2	-0.5
Impedance of arm (left)	1.9	8.9	15.3	-3.9	-1.0	-2.6	-3.1	-2.8	1.1	3.6	3.8	-3.4	2.9	3.1	3.3	3.8	-2.8	-1.5
Arm fat mass (right)	0.1	0.6	3.5	0.3	0.8	0.4	0.8	0.2	-0.7	-0.7	-1.9	0.7	-0.3	-0.6	-0.7	-1.0	0.5	-0.3
Trunk predicted mass	0.8	4.5	10.6	2.6	0.9	1.2	2.2	2.0	-0.9	-2.3	-3.2	2.4	-1.9	-2.0	-2.5	-2.8	2.1	1.0
Standing height	0.1	0.5	1.4	0.4	0.2	0.0	0.7	0.9	-0.5	-0.5	-1.2	0.8	-0.7	-0.6	-0.9	-0.9	1.0	0.9
Length of working week for main job	0.3	0.3	1.5	0.3	-0.2	1.2	0.5	0.7	-0.4	-0.5	-0.3	0.6	-0.6	-0.4	-0.6	-0.4	0.5	0.6
Exposure to tobacco smoke at home	0.9	1.0	2.1	0.3	-0.1	0.9	1.2	1.3	-1.4	-1.4	-0.3	1.4	-0.9	-1.5	-1.1	-0.8	0.4	0.1
Breastfed as a baby	0.9	1.1	2.0	-1.1	-1.3	-1.1	-1.0	-1.2	0.3	0.9	1.0	-0.9	1.2	0.9	0.8	0.8	-1.3	-1.4
Tense / ‘highly strung’	0.3	0.5	1.6	-1.2	-0.5	-0.3	-0.3	-0.4	0.5	0.5	0.8	-0.7	0.7	0.6	0.7	0.8	-0.8	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.4	-0.7	-0.1	0.3	-0.3	-0.3	-0.0	0.5	0.5	-0.5	0.9	0.4	0.5	0.9	-1.0	-1.2
Hair/balding pattern: Pattern 4	0.1	0.4	3.0	0.4	-0.1	-0.0	-0.2	0.2	1.7	0.3	0.4	-0.5	0.5	0.5	0.4	0.5	-0.6	-0.6
Birth weight of first child	0.2	0.4	2.5	-0.8	-1.1	-0.4	-0.1	-0.3	0.1	-0.1	0.5	-0.1	0.8	0.2	0.0	0.2	-1.0	-1.6
Peak expiratory flow (PEF)	0.4	0.9	1.5	1.2	0.4	0.7	0.8	0.8	-0.6	-0.8	-0.8	1.0	-1.1	-1.0	-1.2	-1.2	1.2	1.1
Pulse wave reflection index	0.1	0.2	1.2	-1.1	-0.5	-0.5	-0.1	-0.1	0.4	0.3	0.5	-0.4	0.0	0.5	0.2	0.2	-0.1	0.2
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.6	-0.3	-0.6	0.5	0.3	0.8	-0.1	0.0	0.3	-0.1	-0.4	-0.0	0.2	-0.1	0.5	0.8
Loud music exposure frequency	0.4	0.4	1.5	0.7	1.2	0.2	0.2	0.4	-0.5	-0.2	-0.8	0.4	-0.6	-0.4	-0.3	-0.2	0.9	1.0
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	1.3	-0.2	-0.5	0.1	-0.2	-0.6	-0.3	0.0	-0.1	-0.1	0.7	-0.2	0.4	0.2	-0.7	-1.1
Mouth/teeth dental problems: Bleeding gums	4.0	5.1	8.3	1.4	1.6	2.5	2.4	2.9	-1.7	-2.3	-2.4	2.5	-2.3	-2.4	-2.4	-2.3	2.4	1.8
Blood clot in the leg (DVT)	1.2	1.5	3.6	-0.2	0.7	1.5	1.5	1.7	-1.9	-1.3	-0.5	1.4	-1.1	-1.4	-1.2	-1.1	1.0	0.6
Medication: Paracetamol	0.1	0.2	0.8	-0.7	-0.1	0.8	0.1	0.4	-0.3	-0.1	-0.2	0.3	0.5	-0.3	-0.0	0.3	-0.6	-0.9
Headache pain in last month	0.3	0.5	1.8	-0.7	0.3	0.2	0.7	0.3	-1.3	-0.6	-0.7	1.0	-0.4	-0.9	-0.7	-0.6	0.3	0.1
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.4	0.5	-0.2	1.2	0.5	0.7	-0.1	-0.4	-0.1	0.7	-0.5	-0.8	-0.7	-0.4	0.5	0.5
Glaucoma (self-reported)	0.2	0.2	0.8	-0.6	-0.3	-0.4	-0.5	-0.2	0.5	0.5	0.9	-0.4	-0.1	0.5	0.5	0.2	0.1	0.8
Gout (self-reported)	2.0	2.8	6.0	-1.4	-1.9	-1.1	-1.6	-1.0	1.8	1.6	2.4	-1.5	1.7	1.5	1.6	2.0	-1.9	-1.5
Hypothyroidism/myxoedema (self-reported)	3.6	7.1	11.9	-3.5	-2.3	-2.5	-2.6	-2.7	1.3	2.8	3.2	-2.8	2.8	2.8	2.5	2.6	-2.9	-2.3
Medication: Amlodipine	0.3	0.4	0.8	0.1	-0.3	-0.6	-0.5	-0.9	0.8	0.4	0.5	-0.6	0.6	0.5	0.5	0.5	-0.9	-0.9
Medication: Ventolin 100micrograms inhaler	1.9	2.5	3.9	-0.6	-1.4	-1.9	-1.7	-2.0	1.5	1.4	1.8	-1.5	1.7	1.5	1.6	1.4	-1.7	-1.6
Birth weight	0.0	0.1	0.4	0.1	-0.6	-0.5	-0.1	0.0	0.3	-0.1	0.4	0.2	-0.3	-0.1	-0.0	0.3	0.3	0.4
Chronic bronchitis/emphysema (mother)	2.3	2.6	5.1	1.1	0.8	2.3	2.0	1.7	-1.3	-2.3	-1.2	2.1	-1.1	-2.2	-1.7	-1.7	0.7	-0.3
High blood pressure (siblings)	0.3	0.5	2.1	1.4	1.2	1.0	0.5	-0.1	0.5	-0.6	-1.0	0.3	-0.0	-0.7	-0.2	-0.6	-0.0	-0.5
Forced vital capacity (FVC), Best measure	0.2	0.9	3.5	0.2	-0.6	-1.9	-1.4	-1.3	1.0	1.2	0.2	-0.9	0.4	0.9	0.8	0.7	0.1	0.7
Body fat percentage	0.1	0.3	1.6	-1.3	0.4	-0.3	-0.2	-0.7	-0.5	0.5	-0.4	-0.4	0.7	0.4	0.4	0.4	-0.5	-0.7
Leg fat percentage (right)	0.0	0.1	0.5	-0.7	0.4	-0.2	-0.1	-0.2	-0.1	0.2	-0.6	-0.1	0.4	0.2	0.1	0.1	-0.2	-0.6
Arm fat-free mass (right)	0.8	4.2	9.7	2.1	1.2	1.3	2.2	1.8	-1.0	-2.3	-3.1	2.4	-1.9	-2.0	-2.4	-2.7	2.0	0.9
Exposure to tobacco smoke outside home	0.5	0.7	1.7	0.3	0.3	1.0	1.2	0.9	0.6	-1.3	-0.5	1.2	-0.6	-1.2	-1.0	-0.7	0.3	-0.2
Comparative body size at age 10	2.9	8.1	13.5	1.5	1.3	2.3	3.1	2.8	-3.0	-3.0	-3.7	3.0	-3.1	-2.7	-2.8	-3.5	3.2	2.6
Number of full brothers	0.2	0.2	0.8	0.7	0.4	0.9	0.3	0.5	0.9	-0.5	-0.1	0.5	-0.1	-0.4	-0.4	-0.2	-0.1	-0.4
Worry too long after embarrassment	0.1	0.2	1.2	-1.1	-0.5	-0.2	0.4	0.3	-0.5	-0.0	0.9	0.2	-0.1	-0.4	-0.1	0.2	-0.3	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.6	0.3	0.6	0.6	0.3	0.3	-0.8	-0.3	-0.3	0.4	-0.2	-0.4	-0.1	-0.2	0.2	0.2
Wheeze or whistling in the chest in last year	3.4	6.0	7.3	-1.9	-1.8	-2.7	-2.4	-2.6	2.5	2.2	2.6	-2.4	2.6	2.6	2.5	2.6	-2.7	-2.4
Number of children fathered	0.0	0.0	0.1	0.3	-0.4	-0.4	-0.2	-0.2	0.1	0.1	0.2	-0.1	0.1	0.3	0.2	-0.0	-0.2	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.7	0.9	0.1	0.2	-0.2	0.2	-0.4	0.0	-0.3	0.0	-0.3	-0.1	0.3	-0.2	0.4	0.7
Age at first live birth	0.1	0.2	0.4	0.5	-0.1	-0.7	0.1	-0.5	-0.6	-0.1	-0.6	0.1	-0.4	-0.1	-0.2	-0.6	0.6	0.6
Pulse wave peak to peak time	0.2	0.2	1.3	1.1	-0.7	-0.6	-0.5	-0.5	0.6	0.2	0.1	-0.2	-0.0	0.0	0.4	0.0	0.1	0.4
Health satisfaction	0.9	1.1	2.6	0.3	-0.4	1.3	1.3	1.6	-0.6	-1.1	-0.3	1.2	-1.2	-1.2	-1.3	-1.1	1.0	0.8
Shortness of breath walking on level ground	0.6	0.7	2.4	0.6	0.0	1.4	0.9	1.6	0.7	-0.9	-0.2	0.9	-0.0	-0.9	-0.9	-0.1	-0.4	-1.1
Qualifications: College or University degree	0.1	0.3	1.3	0.2	-0.8	-0.5	-0.0	-0.6	-0.5	-0.3	-1.1	0.1	0.3	-0.2	0.0	-0.6	-0.1	-0.7
Eye problems/disorders: None of the above	1.0	1.2	4.1	2.0	0.7	1.0	1.0	0.9	-0.1	-1.2	-1.4	1.2	-0.8	-1.3	-1.1	-1.0	0.8	0.3
Mouth/teeth dental problems: Loose teeth	0.6	0.7	2.6	-1.6	-1.2	-1.1	-0.5	-0.8	-0.1	0.4	1.0	-0.5	0.6	0.9	0.5	0.4	-0.8	-0.6
Emphysema/chronic bronchitis	5.5	6.2	12.0	-1.2	-1.2	-1.9	-2.8	-2.1	3.5	2.6	2.9	-2.6	2.7	2.5	2.6	2.9	-2.6	-2.2
Medication for pain relief, constipation, heartburn	0.5	0.8	4.0	2.0	0.1	0.0	0.2	1.0	1.3	-0.3	-0.4	0.3	-0.8	-0.4	-0.5	-0.8	1.1	1.2
Neck or shoulder pain in last month	0.5	0.7	3.7	-0.6	-0.4	0.6	1.1	0.2	-1.9	-0.8	-0.6	0.8	-0.5	-0.8	-0.9	-1.0	0.3	-0.1
Medication: Blood pressure	0.1	0.2	0.6	0.8	0.7	-0.3	0.2	0.1	0.1	-0.4	-0.8	0.1	-0.5	-0.1	-0.2	-0.5	0.6	0.4
Angina (self-reported)	0.1	0.2	1.0	-0.9	-1.0	-0.5	-0.0	0.0	-0.3	0.1	0.6	-0.2	0.1	0.1	-0.1	0.1	-0.1	-0.2
Migraine (self-reported)	2.5	3.1	4.9	1.6	1.9	1.8	1.4	1.5	-1.4	-1.6	-2.2	1.5	-1.8	-1.7	-1.6	-2.1	2.0	1.9
Medication: Ibuprofen	1.2	1.4	4.7	-1.7	-0.1	-1.2	-1.1	-2.2	-0.6	1.1	0.7	-1.1	1.1	1.2	1.3	1.1	-1.2	-0.7
Medication: Allopurinol	0.3	0.4	1.3	-0.5	-1.1	-0.3	-0.5	-0.1	0.9	0.3	1.0	-0.4	0.6	0.3	0.5	0.8	-0.8	-0.7
Medication: Omeprazole	0.5	0.6	2.5	-0.8	0.3	-0.3	-0.2	-0.8	0.9	0.4	0.3	-0.6	1.0	0.6	0.5	0.5	-1.2	-1.6
Medication: Seretide 50 evohaler	2.2	2.6	7.6	0.0	-0.8	-1.4	-1.5	-1.6	2.1	0.9	1.2	-1.2	2.1	1.2	1.4	1.6	-2.1	-2.8
Mean time to correctly identify matches	3.2	6.0	7.8	2.1	2.6	2.0	2.8	2.5	-2.0	-2.7	-2.5	2.8	-2.6	-2.6	-2.7	-2.6	2.3	1.7
Heart disease (mother)	0.1	0.1	0.6	-0.5	-0.1	-0.1	0.3	0.7	-0.8	-0.1	-0.2	-0.0	-0.0	0.0	-0.0	-0.1	-0.0	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.1	2.5	3.2	1.2	1.4	1.7	1.6	1.6	-1.4	-1.7	-1.2	1.7	-1.7	-1.5	-1.8	-1.7	1.6	1.4
Whole body fat mass	0.1	0.5	2.7	-0.2	0.8	0.4	0.8	0.2	-1.1	-0.6	-1.6	0.7	-0.2	-0.6	-0.7	-0.8	0.4	-0.2
Leg fat mass (right)	0.1	0.2	1.8	-0.2	0.5	0.1	0.4	0.0	-0.4	-0.3	-1.4	0.4	0.1	-0.3	-0.4	-0.6	0.2	-0.4
Arm predicted mass (right)	0.9	4.7	10.8	2.2	1.3	1.5	2.3	2.0	-1.2	-2.4	-3.3	2.5	-1.9	-2.1	-2.5	-2.8	2.1	1.0
Pulse rate, automated reading	0.9	2.9	5.4	-2.3	-0.7	-1.8	-1.7	-2.0	1.2	1.8	1.5	-1.8	1.7	1.6	1.7	2.0	-1.7	-1.3
Alcohol intake frequency.	0.0	0.1	0.5	-0.7	0.0	-0.1	0.3	0.4	-0.2	-0.1	0.1	-0.0	0.1	0.0	0.1	-0.2	-0.2	-0.4
Comparative height size at age 10	0.3	1.4	5.9	-2.4	-2.0	-1.7	-0.8	-0.6	-0.1	1.3	0.5	-1.1	0.5	1.4	0.9	0.8	-0.1	0.5
Number of full sisters	0.2	0.2	1.1	0.3	-0.6	0.3	0.2	-0.3	-0.1	-0.3	-0.2	0.2	0.5	-0.5	-0.2	0.2	-0.7	-1.1
Suffer from ‘nerves’	0.8	1.2	8.1	0.4	2.8	1.1	1.1	1.1	-0.8	-0.9	-0.9	0.9	-0.9	-1.0	-0.7	-0.4	0.8	0.8
Overall health rating	0.2	0.4	0.9	-0.8	0.6	0.4	0.9	0.4	-0.9	-0.7	-0.1	0.8	-0.2	-0.7	-0.7	-0.3	-0.0	-0.4
Chest pain or discomfort	5.8	8.3	11.6	-2.5	-3.3	-2.8	-2.8	-2.6	2.5	2.5	3.2	-2.7	3.2	2.7	2.7	2.9	-3.4	-3.2
Had major operations	2.0	2.3	6.3	-1.2	-1.9	-2.5	-1.7	-2.2	0.8	1.7	1.4	-1.9	0.9	1.6	1.5	1.0	-0.7	0.1
Age at last live birth	0.1	0.1	0.7	0.1	0.1	-0.2	0.3	-0.3	-0.8	-0.2	-0.6	0.1	-0.2	-0.0	-0.2	-0.4	0.3	0.1
Family relationship satisfaction	0.2	0.2	0.8	-0.7	-0.9	0.2	0.5	0.4	-0.9	-0.4	-0.4	0.4	-0.1	-0.3	-0.2	-0.3	0.0	-0.3
Leg pain on walking	0.1	0.1	0.4	-0.3	0.3	0.2	0.1	-0.4	0.2	-0.2	-0.2	0.1	0.3	-0.1	0.0	0.0	-0.3	-0.6
Qualifications: NVQ or HND or HNC or equivalent	8.5	10.3	16.3	3.2	1.4	4.0	3.5	3.8	-2.0	-3.7	-3.4	3.8	-3.0	-3.7	-3.7	-3.3	2.6	1.5
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.9	-0.1	-1.4	0.1	-0.4	-0.3	0.0	0.1	-0.0	-0.0	0.6	-0.1	0.4	0.1	-0.5	-0.8
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	0.7	0.3	0.1	-0.8	-0.8	-0.6	-0.0	0.7	0.2	-0.7	0.1	0.7	0.4	0.6	0.1	0.7
Medication: Aspirin	1.9	2.6	4.8	-2.2	-1.0	-1.3	-1.1	-1.7	0.8	1.4	1.6	-1.7	1.7	1.7	1.7	1.8	-1.9	-1.8
Supplements: Vitamin C	0.2	0.2	0.8	0.0	0.3	-0.2	0.5	0.8	-0.5	-0.2	-0.0	0.2	-0.7	0.1	-0.5	-0.5	0.7	0.9
Knee pain experienced in last month	1.2	1.9	3.6	-1.9	-1.9	-1.8	-1.3	-1.6	0.5	1.4	1.3	-1.4	1.2	1.4	1.4	1.0	-1.2	-0.6
Hypertension (Self-reported)	0.2	0.6	1.8	0.3	0.3	-0.9	-0.7	-1.0	1.4	0.9	0.4	-1.1	0.2	1.1	0.9	0.6	-0.3	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.1	1.9	-0.4	-0.1	-0.7	-1.2	-1.4	0.9	1.1	0.7	-1.2	1.2	0.9	1.2	1.2	-1.3	-1.1
Illnesses of father: Heart disease	0.3	0.4	0.8	-0.4	-0.8	-0.0	0.7	0.7	-0.8	-0.8	-0.7	0.6	-0.5	-0.8	-0.6	-0.9	0.5	0.2
Illnesses of siblings: Diabetes	1.6	1.9	3.8	0.8	1.2	0.7	1.5	0.5	-2.0	-1.7	-1.4	1.5	-1.6	-1.5	-1.3	-1.7	1.5	1.2
Smoking status: Previous	2.0	3.0	5.9	-2.1	-1.9	-1.9	-1.8	-1.6	1.2	1.8	2.4	-1.9	1.4	2.0	1.7	1.5	-1.3	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	2.2	4.5	5.9	1.8	1.9	2.1	1.9	2.2	-1.9	-2.0	-2.3	2.4	-2.2	-2.3	-2.4	-2.0	2.3	2.1
Whole body fat-free mass	0.7	3.7	9.7	2.3	0.8	1.1	2.0	1.8	-0.8	-2.2	-3.1	2.2	-1.6	-1.8	-2.2	-2.6	1.8	0.7
Leg fat-free mass (right)	0.6	3.1	8.6	2.1	0.9	1.1	1.8	1.6	-0.6	-2.0	-2.9	2.1	-1.5	-1.7	-2.0	-2.3	1.6	0.6
Arm fat percentage (left)	0.0	0.2	1.0	-0.4	0.7	-0.0	0.0	-0.3	-0.5	0.1	-1.0	-0.0	0.3	0.0	0.0	-0.2	-0.1	-0.6
Average weekly red wine intake	2.0	2.9	4.0	-0.8	-1.2	-1.9	-1.9	-1.9	1.6	1.6	2.0	-1.6	1.8	1.8	1.8	1.9	-1.8	-1.5
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.3	1.2	0.4	0.9	0.6	0.7	-0.1	-0.7	-0.8	0.5	-1.2	-0.3	-0.7	-0.7	1.1	1.5
Mood swings	1.7	3.0	5.4	0.7	1.5	2.3	2.1	2.1	-1.5	-1.9	-1.5	1.7	-1.9	-1.6	-1.9	-1.7	1.5	1.4
Loneliness, isolation	0.2	0.3	1.7	-1.3	0.2	-0.1	-0.2	-0.6	0.8	0.3	0.4	-0.3	0.5	0.4	0.5	0.7	-0.7	-0.6
Long-standing illness, disability or infirmity	0.0	0.0	0.1	0.1	-0.1	-0.2	0.3	0.1	-0.1	-0.3	-0.0	0.1	-0.2	-0.3	-0.0	-0.3	0.0	0.1
Ever had bowel cancer screening	0.1	0.1	0.7	0.0	0.0	-0.4	-0.1	0.3	0.8	0.2	0.5	-0.1	-0.2	0.2	-0.0	0.2	0.1	0.3
Diabetes diagnosed by doctor	0.9	1.4	2.3	-1.1	0.5	-0.9	-1.1	-1.0	1.5	1.2	1.0	-1.2	1.4	1.3	1.2	1.4	-1.3	-1.3
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	1.4	-1.0	-1.2	-0.3	-0.8	-0.8	0.6	0.9	0.9	-0.9	1.0	0.9	0.9	1.0	-1.0	-0.8
Friendships satisfaction	0.9	1.1	2.9	0.4	-1.1	1.7	1.3	1.4	-0.5	-1.3	-0.8	1.2	-0.9	-1.3	-1.1	-1.0	0.7	0.3
Qualifications: nursing, teaching	0.6	1.0	2.9	-1.1	-0.8	-1.3	-0.7	-1.7	0.0	0.6	0.4	-0.7	1.1	0.7	1.0	0.4	-1.2	-1.4
Commuting to job workplace: Walk	0.1	0.1	0.5	-0.1	-0.5	-0.6	-0.3	-0.7	0.2	0.3	0.3	-0.4	0.1	0.4	0.3	-0.0	-0.1	0.1
Eye problems/disorders: Cataract	0.3	0.4	1.3	-1.1	-1.1	-0.7	-0.3	-0.7	-0.4	0.5	0.5	-0.6	0.4	0.7	0.4	0.1	-0.4	-0.2
Mouth/teeth dental problems: Mouth ulcers	4.6	7.3	10.6	2.3	1.7	2.2	2.9	2.8	-2.7	-2.9	-2.8	2.8	-3.0	-2.8	-2.7	-3.3	3.0	2.4
Medication for cholesterol	1.3	2.0	3.3	1.8	1.4	1.2	1.2	1.6	-1.4	-1.4	-1.4	1.6	-1.2	-1.8	-1.4	-1.2	1.4	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	3.7	-1.4	-1.9	-0.5	-0.5	-0.9	0.3	0.5	1.1	-0.6	1.1	0.5	0.5	0.7	-1.3	-1.4
Back pain experienced in last month	0.9	1.3	3.2	-0.3	0.3	0.9	1.5	1.1	-1.8	-1.2	-1.0	1.2	-1.1	-1.0	-1.4	-1.3	1.0	0.7
Mineral and other dietary supplements	0.2	0.2	0.8	-0.6	0.1	0.4	-0.3	0.3	0.6	0.3	0.3	-0.1	0.6	0.0	0.3	0.9	-0.6	-0.7
Breast cancer (self-reported)	0.6	0.7	2.1	-0.9	-0.5	-1.2	-0.8	-0.6	0.4	0.9	1.5	-0.9	0.6	1.0	0.9	0.8	-0.7	-0.2
Asthma (self-reported)	1.1	2.2	3.9	-0.6	-1.9	-1.7	-1.7	-1.7	2.0	1.3	1.8	-1.4	1.3	1.4	1.5	1.3	-1.3	-1.0
Osteoporosis (self-reported)	3.7	4.5	7.3	-1.3	-1.2	-1.8	-2.3	-1.9	2.6	2.3	2.5	-2.2	2.3	1.9	1.9	2.7	-2.4	-2.0
Osteoarthritis (self-reported)	0.1	0.2	0.6	-0.7	0.3	-0.8	-0.1	-0.4	-0.1	0.3	-0.3	-0.6	0.1	0.6	0.3	0.0	-0.1	0.1
Medication: Aspirin	3.4	4.4	7.0	-2.6	-1.4	-2.0	-1.7	-2.3	1.3	2.0	2.2	-2.3	2.1	2.3	2.2	2.3	-2.3	-1.9
Medication: Gliclazide	0.7	0.7	4.1	-0.3	2.0	-0.8	-0.9	-0.5	0.2	1.0	0.2	-1.0	0.3	0.9	0.9	0.9	0.0	0.7
Illnesses of father: None of the above (group 1)	1.1	1.3	2.3	1.4	1.5	1.3	1.1	1.2	-0.6	-1.2	-1.1	1.3	-1.1	-0.9	-1.5	-0.9	1.0	0.7
Smoking status: Current	0.3	0.5	2.8	-1.3	-1.7	-0.2	-0.1	0.2	0.7	0.2	0.3	-0.2	0.7	0.4	0.1	0.4	-0.8	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.7	-0.0	0.4	-0.8	0.0	-0.4	-0.4	0.0	-0.3	-0.1	-0.3	0.1	-0.2	-0.4	0.5	0.6
Whole body water mass	0.7	3.9	10.0	2.2	0.8	1.1	2.0	1.8	-0.9	-2.2	-3.2	2.3	-1.7	-1.9	-2.3	-2.7	1.9	0.8
Leg predicted mass (right)	0.6	3.0	8.4	2.1	0.9	1.1	1.7	1.6	-0.5	-1.9	-2.9	2.0	-1.4	-1.6	-1.9	-2.3	1.6	0.6
Arm fat mass (left)	0.2	0.8	4.0	0.3	0.9	0.4	0.9	0.3	-0.9	-0.8	-2.0	0.9	-0.5	-0.7	-0.9	-1.2	0.7	-0.0
Number of self-reported non-cancer illnesses	2.7	4.7	7.5	-1.9	-1.0	-2.1	-2.3	-2.7	2.3	2.3	1.9	-2.4	2.3	2.2	2.6	2.2	-2.2	-1.6
Average weekly champagne plus white wine intake	0.8	1.2	2.1	-0.1	0.5	1.3	1.2	1.4	-1.5	-1.1	-1.2	1.0	-1.0	-1.2	-1.1	-1.1	1.0	0.7
Miserableness	0.5	0.9	1.9	0.4	0.8	1.3	1.4	1.0	-0.3	-1.3	-0.9	1.0	-0.8	-1.1	-1.1	-0.8	0.4	-0.0
Guilty feelings	0.0	0.0	0.1	-0.1	-0.2	0.0	0.3	0.1	-0.3	-0.3	0.0	0.2	-0.2	-0.2	-0.0	0.0	-0.1	-0.0
Wears glasses or contact lenses	0.4	0.5	1.2	0.4	1.1	0.2	0.8	0.1	-0.6	-0.7	-1.1	0.5	-0.7	-0.5	-0.6	-1.0	0.7	0.4
Ever taken oral contraceptive pill	0.9	1.0	3.1	-1.1	0.0	-1.6	-0.9	-1.8	-0.5	1.0	0.9	-1.0	0.6	1.0	1.2	0.9	-0.7	-0.2
Hearing aid user	0.6	0.7	1.9	0.9	-1.2	1.4	0.6	1.3	0.3	-0.7	-0.2	0.8	-0.7	-0.9	-0.6	-0.4	0.6	0.6
Mother’s age at death	0.2	0.2	0.8	0.1	0.8	0.5	-0.0	0.9	0.9	0.3	0.5	-0.2	0.1	0.1	0.1	0.2	0.0	0.2
Financial situation satisfaction	0.1	0.1	0.4	-0.2	-0.5	0.6	0.4	0.1	0.1	-0.3	0.4	0.1	-0.1	-0.3	-0.2	0.0	-0.3	-0.3
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.7	-0.4	-1.3	0.2	-0.1	-0.1	0.7	-0.1	0.5	0.1	0.6	0.2	0.1	0.4	-0.8	-1.1
Commuting to job workplace: Public transport	0.6	0.7	2.7	0.6	1.7	0.5	0.5	0.7	-0.3	-0.5	-0.7	0.4	-1.0	-0.4	-0.6	-0.6	1.0	1.3
Eye problems/disorders: Glaucoma	0.4	0.5	1.1	-1.0	0.0	-1.0	-1.0	-0.9	0.0	0.9	0.6	-0.7	0.3	0.8	0.8	0.4	-0.0	0.7
Medication: Blood pressure	1.0	1.8	3.5	-1.4	-0.0	-1.8	-1.3	-1.9	1.1	1.6	1.1	-1.8	1.0	1.8	1.6	1.2	-1.0	-0.2
Pain type(s) experienced in last month: Hip pain	1.2	1.5	8.5	-2.1	-2.9	-1.1	-0.5	-0.6	-0.3	0.6	1.2	-0.8	1.0	0.6	0.7	0.5	-1.2	-1.2
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.8	0.3	-0.9	-0.5	0.1	-0.4	-0.5	-0.2	0.1	-0.1	-0.4	0.2	-0.0	-0.6	0.3	0.4
High cholesterol (Self-reported)	4.1	7.2	10.8	-3.3	-1.8	-2.2	-2.5	-2.7	1.4	2.6	2.3	-2.8	3.3	2.7	2.9	2.8	-3.3	-3.2
Medication: Bendroflumethiazide	0.5	0.7	2.1	-0.8	0.3	-1.5	-0.8	-1.1	0.5	0.9	0.4	-1.1	0.7	1.2	1.0	0.7	-0.6	-0.4
Medication: Paracetamol	0.2	0.2	0.8	-0.2	0.1	0.8	0.3	0.5	-0.9	-0.4	-0.6	0.7	0.1	-0.6	-0.3	-0.2	-0.2	-0.5
Medication: Lisinopril	0.4	0.5	2.2	-0.6	-0.8	-1.5	-0.7	-0.5	0.8	0.7	0.6	-0.9	0.3	1.0	0.8	0.3	-0.1	0.0
Medication: Atorvastatin	0.2	0.2	0.7	-0.7	-0.8	-0.1	-0.3	0.6	0.1	0.4	0.6	-0.4	0.3	0.3	0.3	0.5	-0.4	-0.2
Illnesses of father: High blood pressure	0.7	0.9	2.1	-0.5	0.3	-0.5	-0.9	-1.4	1.5	1.0	0.9	-1.1	0.9	0.9	1.2	0.9	-1.0	-0.6
Alcohol drinker status: Never	3.0	3.6	6.5	-1.7	-2.2	-1.6	-1.9	-1.3	1.9	1.9	2.5	-2.1	1.7	1.8	2.1	2.1	-1.9	-1.1
Ever smoked	0.1	0.2	1.1	-1.1	-0.6	-0.0	-0.1	0.1	-0.1	0.2	0.7	-0.2	0.3	0.4	0.1	0.2	-0.4	-0.2
Basal metabolic rate	0.6	3.4	9.7	2.1	0.9	1.1	1.9	1.7	-0.8	-2.0	-3.1	2.1	-1.6	-1.7	-2.1	-2.5	1.8	0.8
Leg fat percentage (left)	0.1	0.3	1.3	-0.2	1.1	0.5	0.4	0.2	-0.5	-0.2	-1.1	0.4	-0.1	-0.3	-0.4	-0.3	0.3	-0.1
Arm fat-free mass (left)	0.9	4.6	10.8	2.2	0.9	1.4	2.3	1.9	-1.2	-2.4	-3.3	2.4	-2.0	-2.0	-2.5	-2.8	2.1	1.1
Number of operations (self-reported)	0.9	1.4	3.8	-2.0	-1.3	-1.6	-1.2	-1.4	-0.8	1.4	1.2	-1.3	0.6	1.1	1.0	0.6	-0.4	0.5
Average weekly beer plus cider intake	0.1	0.2	0.6	-0.1	-0.4	-0.1	-0.4	-0.5	0.7	0.4	0.6	-0.2	0.3	0.4	0.4	0.8	-0.3	-0.1
Irritability	0.4	0.6	4.9	-2.2	-1.2	-0.7	-0.3	-0.2	-0.6	0.4	0.5	-0.6	0.5	0.5	0.5	0.2	-0.5	-0.2
Risk taking	3.9	5.7	12.1	-2.6	-3.5	-2.2	-2.3	-2.2	2.4	2.5	2.8	-2.5	1.9	2.5	2.3	2.2	-1.9	-0.8
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.5	-1.0	-0.3	-1.2	-0.9	-1.1	0.6	0.8	1.0	-0.9	0.9	0.7	0.8	0.7	-0.8	-0.7
Fractured/broken bones in last 5 years	0.6	0.7	2.6	0.6	-0.1	0.2	0.8	0.5	-0.9	-0.6	-0.7	0.6	-1.3	-0.5	-0.8	-1.1	1.3	1.6
Age started oral contraceptive pill	0.7	0.8	4.2	1.5	2.0	0.7	0.5	1.1	-0.1	-0.5	-0.7	0.6	-0.7	-0.7	-0.7	-0.3	0.8	0.7
Diastolic blood pressure, automated reading	0.2	0.7	3.3	0.4	1.8	-0.4	-0.5	-0.7	0.5	0.7	-0.7	-0.5	-0.5	0.3	0.1	-0.1	1.0	1.7
Ever depressed for a whole week	0.3	0.4	0.8	-0.8	0.2	-0.3	-0.6	-0.4	0.6	0.9	0.6	-0.9	0.6	0.7	0.9	0.8	-0.5	0.0
Unable to work because of sickness or disability	2.3	3.0	5.8	2.4	1.8	2.2	1.7	1.8	-0.6	-2.0	-2.0	1.9	-1.4	-2.0	-1.7	-1.6	1.2	0.5
Commuting to job workplace: Cycle	0.1	0.1	0.8	0.1	0.3	-0.0	0.1	0.2	0.2	0.1	0.0	-0.1	-0.5	0.2	-0.0	0.0	0.7	0.9
Myopia	0.5	0.7	2.3	1.0	1.5	0.2	0.1	-0.4	-1.1	-0.1	-1.0	0.1	-0.8	-0.3	-0.3	-0.6	1.0	1.4
Vascular/heart problems diagnosed by doctor	0.2	0.7	1.6	0.5	-0.3	1.3	0.7	1.1	-0.8	-0.9	-0.6	1.2	-0.4	-1.1	-0.9	-0.7	0.4	-0.1
Cholesterol lowering medication	1.8	2.7	5.2	-2.3	-1.6	-1.6	-1.5	-1.7	0.5	1.6	1.7	-1.7	1.7	1.7	1.7	1.4	-1.8	-1.4
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.9	-0.4	0.5	0.2	0.4	-0.1	-0.3	-0.3	-0.4	0.1	0.3	-0.2	-0.2	-0.3	-0.5	-0.9
Pain experienced in last month	0.8	1.4	4.1	0.4	0.1	-0.7	-1.5	-1.1	2.0	1.2	1.0	-1.4	1.1	1.3	1.4	1.3	-1.0	-0.6
Supplements: Calcium	3.3	3.7	5.7	-1.7	-1.3	-2.1	-1.7	-1.8	2.2	1.9	2.4	-2.0	2.0	2.2	1.6	1.9	-2.1	-1.9
Basal cell carcinoma (self-reported)	0.4	0.5	1.7	1.1	0.1	1.1	0.5	0.1	0.2	-0.7	-0.5	0.9	-0.1	-1.3	-0.9	-0.5	0.1	-0.5
Heart attack/myocardial infarction (self-reported)	0.2	0.2	1.1	-0.8	0.5	-0.0	0.6	0.7	-1.1	-0.3	-0.2	0.3	-0.1	-0.2	-0.2	-0.0	0.0	-0.3
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	3.9	-0.4	0.7	1.4	1.5	1.5	-2.0	-1.3	-0.5	1.3	-1.0	-1.3	-1.2	-1.0	1.0	0.6
Heart disease (siblings)	0.2	0.2	1.4	-0.6	0.1	0.1	0.0	-0.2	-0.5	-0.1	0.2	0.1	0.6	-0.1	0.2	0.3	-0.7	-1.2
Alcohol drinker status: Previous	0.1	0.1	0.7	-0.2	0.8	0.3	0.5	0.3	-0.0	-0.2	-0.2	0.1	-0.0	-0.1	-0.1	-0.1	-0.0	-0.3
Pack years of smoking	0.2	0.3	1.0	0.6	1.0	0.9	0.5	-0.0	0.9	-0.5	-0.5	0.4	0.1	-0.3	-0.2	0.1	-0.3	-0.8
Impedance of whole body	1.7	8.5	16.6	-4.1	-1.2	-2.1	-2.9	-2.7	1.1	3.5	3.9	-3.3	2.7	3.0	3.2	3.9	-2.6	-1.2
Leg fat mass (left)	0.2	0.7	3.4	0.2	1.0	0.5	0.9	0.4	-0.8	-0.7	-1.8	0.8	-0.4	-0.7	-0.8	-1.0	0.6	-0.1
Arm predicted mass (left)	0.9	4.4	10.3	2.2	0.9	1.4	2.2	1.9	-1.1	-2.4	-3.2	2.4	-2.0	-2.0	-2.5	-2.8	2.1	1.1