TWAS
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Traits
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Traits
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Ulcerative Colitis (UC)
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chr1:67,357,596-67,972,435
Best TWAS P=1.38e-09 · Best GWAS P=2e-41 conditioned to 5.82e-38
67.4M
67.5M
67.6M
67.7M
67.8M
67.9M
68M
0
10
20
30
40
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Rectum Adenocarcinoma
IL23R
0.17
0.03
blup
108
0.15
0.00023
-0.73
6.1
1.4e-09
-0.11
0.08
0.05
TRUE
1
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
IL23R
0.06
0.03
blup
107
0.03
0.00700
3.63
5.7
1.2e-08
-0.13
0.15
0.10
FALSE