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chr2:60,466,491-62,460,013

Best TWAS P=2.42e-18 · Best GWAS P=4.33e-23 conditioned to 0.000159

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	KIAA1841	0.05	0.05	enet	15	0.06	1.2e-07	-4.2	-5.2	2.3e-07	-0.38	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	XPO1	0.06	0.03	bslmm	313	0.03	1.4e-04	-4.9	5.5	5.1e-08	0.36	0.86	0.07	FALSE
3	GTEx	Adrenal Gland	KIAA1841	0.13	0.01	enet	15	0.02	4.6e-02	4.6	-5.1	3.0e-07	-0.35	0.07	0.21	FALSE
4	GTEx	Adrenal Gland	AC016747.3	0.26	0.23	enet	14	0.13	1.9e-05	4.1	-5.5	4.4e-08	-0.45	0.93	0.01	FALSE
5	GTEx	Brain Cerebellar Hemisphere	KIAA1841	0.16	0.08	enet	10	0.09	2.7e-03	-4.2	-6.2	7.9e-10	-0.41	0.28	0.12	FALSE
6	GTEx	Brain Cerebellar Hemisphere	AHSA2	0.35	0.22	enet	12	0.38	7.8e-11	-4.6	-5.3	9.7e-08	-0.45	0.90	0.04	FALSE
7	GTEx	Brain Cerebellum	RP11-493E12.2	0.30	0.01	enet	27	0.10	6.5e-04	-5.4	5.2	2.4e-07	0.08	0.09	0.05	FALSE
8	GTEx	Brain Hippocampus	RP11-493E12.2	0.14	0.08	lasso	7	0.09	3.9e-03	-4.7	5.9	4.0e-09	0.44	0.14	0.07	FALSE
9	GTEx	Brain Nucleus accumbens basal ganglia	KIAA1841	0.17	0.16	lasso	3	0.18	1.7e-05	-5.7	-6.4	1.5e-10	-0.59	0.27	0.33	FALSE
10	GTEx	Breast Mammary Tissue (Male)	AHSA2	0.27	0.12	lasso	6	0.08	6.3e-03	-5.8	-7.5	7.6e-14	-0.76	0.02	0.86	FALSE
11	GTEx	Breast Mammary Tissue (Female)	AHSA2	0.24	0.13	lasso	7	0.15	3.2e-05	4.7	-5.3	1.3e-07	-0.46	0.34	0.04	FALSE
12	GTEx	Cells EBV-transformed lymphocytes	AHSA2	0.33	0.13	lasso	3	0.25	1.4e-08	4.1	-5.5	5.1e-08	-0.34	0.20	0.04	FALSE
13	GTEx	Cells Transformed fibroblasts	AHSA2	0.32	0.33	enet	16	0.36	1.2e-27	4.1	-5.3	1.2e-07	-0.48	1.00	0.00	FALSE
14	GTEx	Colon Sigmoid	AHSA2	0.42	0.29	enet	17	0.43	1.1e-16	4.2	-5.2	1.8e-07	-0.43	1.00	0.00	FALSE
15	GTEx	Colon Transverse	AC010733.5	0.12	0.00	lasso	6	0.00	4.5e-01	3.8	-7.5	4.8e-14	-0.77	0.02	0.77	FALSE
16	GTEx	Esophagus Mucosa	AHSA2	0.23	0.12	enet	28	0.18	4.5e-12	4.2	-6.5	1.0e-10	-0.39	1.00	0.00	FALSE
17	GTEx	Esophagus Muscularis	AHSA2	0.44	0.39	enet	24	0.46	7.4e-31	4.1	-5.5	3.8e-08	-0.45	1.00	0.00	FALSE
18	GTEx	Heart Atrial Appendage	AHSA2	0.24	0.19	enet	19	0.18	1.3e-08	4.1	-6.6	4.1e-11	-0.51	0.98	0.02	FALSE
19	GTEx	Heart Left Ventricle	AHSA2	0.13	0.08	lasso	8	0.07	1.2e-04	4.1	-5.6	2.2e-08	-0.46	0.87	0.05	FALSE
20	GTEx	Nerve Tibial	KIAA1841	0.06	0.01	lasso	4	0.02	1.5e-02	-4.7	-7.6	4.0e-14	-0.54	0.26	0.50	FALSE
21	GTEx	Skin Not Sun Exposed Suprapubic	AHSA2	0.25	0.23	enet	13	0.28	2.1e-15	-5.4	-5.9	3.1e-09	-0.36	1.00	0.00	FALSE
22	GTEx	Skin Sun Exposed Lower leg	AHSA2	0.16	0.14	lasso	8	0.23	1.4e-18	-4.4	-5.8	7.2e-09	-0.39	1.00	0.00	FALSE
23	GTEx	Stomach	AHSA2	0.22	0.17	enet	21	0.24	1.0e-11	4.3	-5.8	9.0e-09	-0.50	1.00	0.00	FALSE
24	GTEx	Thyroid	KIAA1841	0.06	0.01	enet	18	0.02	1.0e-02	-4.3	-6.8	8.1e-12	-0.38	0.38	0.03	FALSE
25	GTEx	Uterus	RP11-493E12.2	0.16	0.02	lasso	5	0.05	3.6e-02	-6.1	6.5	9.7e-11	0.43	0.07	0.12	FALSE
26	GTEx	Whole Blood	RP11-493E12.2	0.04	0.02	lasso	6	0.01	1.8e-02	-5.2	5.4	5.4e-08	0.22	0.58	0.04	FALSE
27	YFS	Blood	AHSA2	0.50	0.46	enet	32	0.62	3.1e-265	4.1	-6.1	8.3e-10	-0.42	1.00	0.00	FALSE
28	YFS	Blood	PEX13	0.01	0.00	blup	334	0.01	6.7e-03	-5.2	5.8	8.0e-09	0.49	0.13	0.18	FALSE
29	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	KIAA1841	0.05	0.02	blup	61	0.02	4.5e-03	-5.4	-5.8	6.6e-09	-0.22	0.01	0.83	FALSE
30	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	PEX13	0.06	0.03	lasso	3	0.04	1.3e-02	7.8	8.7	2.4e-18	0.90	0.00	0.91	TRUE
31	The Cancer Genome Atlas	Rectum Adenocarcinoma	AHSA2	0.12	0.13	lasso	2	0.07	1.1e-02	-5.4	-5.8	8.0e-09	-0.31	0.00	0.72	FALSE
32	The Cancer Genome Atlas	Stomach Adenocarcinoma	AHSA2	0.15	0.04	blup	39	0.09	8.4e-07	3.6	-5.2	1.6e-07	-0.36	0.09	0.90	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	PUS10	0.04	0.00	blup	64	0.01	2.4e-02	-7.5	5.2	1.6e-07	0.08	0.05	0.04	TRUE