TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Pulse rate, automated reading
:
→
chr1:5,611,729-7,016,109
Best TWAS P=2.56e-11 · Best GWAS P=9e-18 conditioned to 6.18e-08
5.6M
5.8M
6M
6.2M
6.4M
6.6M
6.8M
7M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
ICMT
0.08
0.01
blup
44
0.05
8.9e-07
8.6
-6.7
2.6e-11
-0.76
0.00
1.00
TRUE
1
GTEx
Breast Mammary Tissue (Male)
GPR153
0.07
-0.01
lasso
3
0.00
3.2e-01
6.1
-5.8
5.0e-09
-0.78
0.04
0.12
FALSE
2
The Cancer Genome Atlas
Colon Adenocarcinoma
ICMT
0.09
0.00
blup
45
0.01
4.8e-02
4.9
-5.2
2.6e-07
-0.65
0.01
0.17
FALSE