Best TWAS P=2.04e-08 · Best GWAS P=1.78e-09 conditioned to 0.0276
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | PAFAH2 | 0.06 | 0.04 | enet | 12 | 0.04 | 1.7e-14 | -5.7 | 5.1 | 2.9e-07 | -0.67 | 0.01 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | TRIM63 | 0.03 | 0.02 | blup | 33 | 0.02 | 4.6e-03 | -4.0 | -5.3 | 9.6e-08 | 0.91 | 0.02 | 0.76 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SLC30A2 | 0.03 | 0.02 | lasso | 3 | 0.01 | 1.1e-02 | -5.4 | 5.6 | 2.0e-08 | -0.91 | 0.01 | 0.94 | TRUE |
| 4 | The Cancer Genome Atlas | Rectum Adenocarcinoma | TRIM63 | 0.28 | 0.22 | lasso | 3 | 0.20 | 1.7e-05 | -5.4 | -5.5 | 3.8e-08 | 0.90 | 0.01 | 0.96 | FALSE |