Best TWAS P=1.74e-11 · Best GWAS P=3.34e-09 conditioned to 0.383
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | RABGAP1L | 0.12 | 0.04 | enet | 17 | 0.05 | 1.0e-03 | -5.0 | -5.5 | 3.2e-08 | 0.50 | 0.34 | 0.62 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | RABGAP1L | 0.23 | 0.03 | enet | 25 | 0.10 | 4.8e-09 | -4.8 | -6.3 | 2.8e-10 | 0.55 | 0.49 | 0.51 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | KIAA0040 | 0.10 | 0.06 | enet | 15 | 0.03 | 1.2e-03 | 5.2 | -6.7 | 1.7e-11 | 0.11 | 0.07 | 0.88 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ANKRD45 | 0.14 | 0.01 | lasso | 4 | 0.07 | 6.9e-08 | -5.1 | -5.9 | 3.0e-09 | 0.79 | 0.00 | 0.82 | TRUE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ANKRD45 | 0.09 | 0.08 | enet | 9 | 0.08 | 7.2e-09 | -5.1 | -5.5 | 2.9e-08 | 0.54 | 0.00 | 1.00 | FALSE |