Best TWAS P=1.25e-09 · Best GWAS P=5.07e-10 conditioned to 0.00911
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | ADCK1 | 0.60 | 0.19 | lasso | 15 | 0.23 | 2.4e-07 | 3.7 | -5.5 | 4.6e-08 | -0.73 | 0.01 | 0.98 | FALSE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ADCK1 | 0.04 | 0.07 | enet | 4 | 0.07 | 3.0e-06 | -4.8 | 5.2 | 2.5e-07 | 0.56 | 0.55 | 0.26 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | ADCK1 | 0.05 | 0.03 | blup | 147 | 0.05 | 1.3e-06 | 4.4 | 6.1 | 1.3e-09 | 0.73 | 0.14 | 0.85 | TRUE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | ADCK1 | 0.04 | 0.02 | blup | 147 | 0.01 | 5.0e-02 | -3.7 | 5.7 | 1.2e-08 | 0.67 | 0.14 | 0.52 | FALSE |