Best TWAS P=5.45e-50 · Best GWAS P=3.06e-50 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | FLRT2 | 0.11 | 0.01 | enet | 45 | 0.06 | 2.6e-05 | 5.9 | 9.2 | 3.1e-20 | -0.58 | 0.02 | 0.93 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Female) | FLRT2 | 0.06 | 0.02 | lasso | 3 | 0.03 | 4.9e-02 | -14.9 | 14.8 | 7.0e-50 | -0.99 | 0.01 | 0.88 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | FLRT2 | 0.22 | 0.13 | enet | 25 | 0.12 | 2.1e-09 | 4.1 | 6.2 | 5.7e-10 | -0.25 | 1.00 | 0.00 | FALSE |
| 4 | GTEx | Heart Atrial Appendage | FLRT2 | 0.21 | 0.06 | lasso | 3 | 0.05 | 2.3e-03 | -14.9 | 14.9 | 5.5e-50 | -1.00 | 0.01 | 0.98 | TRUE |
| 5 | GTEx | Nerve Tibial | FLRT2 | 0.21 | 0.14 | enet | 12 | 0.15 | 8.4e-11 | -14.9 | 13.6 | 4.9e-42 | -0.92 | 0.00 | 1.00 | FALSE |
| 6 | GTEx | Skin Not Sun Exposed Suprapubic | FLRT2 | 0.21 | 0.05 | lasso | 5 | 0.03 | 1.1e-02 | 5.0 | 9.0 | 1.8e-19 | -0.50 | 0.03 | 0.84 | FALSE |
| 7 | GTEx | Skin Sun Exposed Lower leg | FLRT2 | 0.08 | 0.02 | enet | 22 | 0.00 | 2.0e-01 | -9.5 | 7.4 | 1.5e-13 | -0.41 | 0.14 | 0.22 | FALSE |