Best TWAS P=4.06e-13 · Best GWAS P=1.59e-15 conditioned to 4.04e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | RPS6KA5 | 0.08 | 0.07 | lasso | 2 | 0.06 | 5.3e-05 | -5.2 | 5.4 | 8.2e-08 | -0.61 | 0.66 | 0.11 | FALSE |
| 2 | GTEx | Heart Atrial Appendage | C14orf159 | 0.18 | 0.10 | lasso | 4 | 0.06 | 1.6e-03 | -6.8 | -7.2 | 4.1e-13 | 0.33 | 0.02 | 0.93 | TRUE |
| 3 | GTEx | Spleen | C14orf159 | 0.30 | 0.21 | lasso | 5 | 0.21 | 3.6e-06 | -5.9 | 6.1 | 1.1e-09 | -0.55 | 0.09 | 0.34 | FALSE |
| 4 | METSIM | Adipose | C14orf159 | 0.04 | 0.00 | blup | 464 | 0.01 | 4.0e-03 | -8.0 | 5.3 | 1.1e-07 | -0.63 | 0.01 | 0.97 | FALSE |