Best TWAS P=8.47e-09 · Best GWAS P=1.59e-08 conditioned to 0.0885
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Nucleus accumbens basal ganglia | TPM1 | 0.37 | 0.22 | lasso | 8 | 0.01 | 0.1400 | -5.6 | -5.5 | 4.3e-08 | 0.95 | 0.00 | 0.98 | FALSE |
2 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | LACTB | 0.19 | 0.08 | blup | 52 | 0.07 | 0.0014 | -4.2 | 5.8 | 8.5e-09 | -0.81 | 0.01 | 0.68 | TRUE |