Best TWAS P=7.19e-08 · Best GWAS P=9.69e-09 conditioned to 0.017
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Thyroid | ZNF839 | 0.10 | 0.08 | enet | 9 | 0.13 | 5.6e-10 | 3.6 | 5.4 | 7.2e-08 | 0.80 | 0.05 | 0.95 | TRUE |
2 | YFS | Blood | HSP90AA1 | 0.02 | 0.02 | lasso | 2 | 0.02 | 3.2e-07 | 5.3 | -5.2 | 1.8e-07 | -0.58 | 0.07 | 0.92 | FALSE |
3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HSP90AA1 | 0.03 | 0.00 | blup | 49 | 0.01 | 1.4e-02 | 4.7 | -5.1 | 3.1e-07 | -0.58 | 0.01 | 0.81 | FALSE |