[Hub]/) : Traits : Pulse rate, automated reading :

chr15:71,418,503-74,291,976

Best TWAS P=6.06e-49 · Best GWAS P=3.89e-59 conditioned to 0

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NEO1 0.05 0.00 bslmm 373 0.02 1.5e-03 0.58 -9.2 4.4e-20 0.27 0.06 0.11 FALSE
2 GTEx Adipose Subcutaneous MYO9A 0.06 0.03 lasso 2 0.01 4.7e-02 -5.36 5.2 2.1e-07 -0.06 0.04 0.88 FALSE
3 GTEx Artery Tibial MYO9A 0.07 0.08 enet 11 0.09 2.5e-07 -5.45 5.2 2.1e-07 -0.07 0.03 0.97 TRUE
4 GTEx Breast Mammary Tissue MYO9A 0.19 0.02 lasso 8 0.03 9.4e-03 -5.36 5.8 6.5e-09 -0.03 0.03 0.91 TRUE
5 GTEx Heart Atrial Appendage RP11-1006G14.4 0.12 0.06 lasso 11 0.05 2.3e-03 -5.36 -6.0 2.3e-09 0.18 0.10 0.25 TRUE
6 GTEx Nerve Tibial MYO9A 0.13 0.13 lasso 3 0.11 2.1e-08 -5.44 5.6 1.8e-08 -0.02 0.00 1.00 FALSE
7 GTEx Nerve Tibial NEO1 0.07 0.09 lasso 2 0.09 3.9e-07 -5.96 -5.9 4.4e-09 0.11 0.95 0.00 TRUE
8 GTEx Pituitary BBS4 0.27 0.02 enet 21 0.05 2.1e-02 -5.10 -7.5 8.3e-14 0.07 0.09 0.15 FALSE
9 GTEx Pituitary HEXA 0.15 0.02 enet 30 0.03 4.7e-02 2.38 -5.6 2.0e-08 0.02 0.12 0.10 TRUE
10 GTEx Spleen NEO1 0.39 0.00 lasso 9 0.01 2.0e-01 12.05 -10.7 1.3e-26 0.22 0.06 0.05 TRUE
11 NTR Blood NEO1 0.04 0.01 lasso 4 0.02 4.1e-06 9.86 -11.3 8.4e-30 0.33 0.92 0.02 TRUE
12 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma NR2E3 0.07 0.02 blup 38 0.05 4.4e-03 -4.48 5.3 1.1e-07 -0.04 0.01 0.28 TRUE
13 The Cancer Genome Atlas Thyroid Carcinoma HCN4 0.03 0.00 blup 52 0.02 2.0e-03 2.72 14.7 6.1e-49 -0.52 0.01 0.45 TRUE
14 The Cancer Genome Atlas Thyroid Carcinoma NEO1 0.03 0.02 lasso 3 0.02 6.2e-03 12.18 -11.1 7.2e-29 0.29 0.05 0.50 TRUE