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chr15:71,418,503-74,291,976

Best TWAS P=6.06e-49 · Best GWAS P=3.89e-59 conditioned to 0

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
13	The Cancer Genome Atlas	Thyroid Carcinoma	HCN4	0.03	0.00	blup	52	0.02	2.0e-03	2.72	14.7	6.1e-49	-0.52	0.01	0.45	TRUE
11	NTR	Blood	NEO1	0.04	0.01	lasso	4	0.02	4.1e-06	9.86	-11.3	8.4e-30	0.33	0.92	0.02	TRUE
14	The Cancer Genome Atlas	Thyroid Carcinoma	NEO1	0.03	0.02	lasso	3	0.02	6.2e-03	12.18	-11.1	7.2e-29	0.29	0.05	0.50	TRUE
10	GTEx	Spleen	NEO1	0.39	0.00	lasso	9	0.01	2.0e-01	12.05	-10.7	1.3e-26	0.22	0.06	0.05	TRUE
5	GTEx	Heart Atrial Appendage	RP11-1006G14.4	0.12	0.06	lasso	11	0.05	2.3e-03	-5.36	-6.0	2.3e-09	0.18	0.10	0.25	TRUE
7	GTEx	Nerve Tibial	NEO1	0.07	0.09	lasso	2	0.09	3.9e-07	-5.96	-5.9	4.4e-09	0.11	0.95	0.00	TRUE
4	GTEx	Breast Mammary Tissue	MYO9A	0.19	0.02	lasso	8	0.03	9.4e-03	-5.36	5.8	6.5e-09	-0.03	0.03	0.91	TRUE
9	GTEx	Pituitary	HEXA	0.15	0.02	enet	30	0.03	4.7e-02	2.38	-5.6	2.0e-08	0.02	0.12	0.10	TRUE
12	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	NR2E3	0.07	0.02	blup	38	0.05	4.4e-03	-4.48	5.3	1.1e-07	-0.04	0.01	0.28	TRUE
3	GTEx	Artery Tibial	MYO9A	0.07	0.08	enet	11	0.09	2.5e-07	-5.45	5.2	2.1e-07	-0.07	0.03	0.97	TRUE
1	CommonMind	Brain Pre-frontal Cortex	NEO1	0.05	0.00	bslmm	373	0.02	1.5e-03	0.58	-9.2	4.4e-20	0.27	0.06	0.11	FALSE
8	GTEx	Pituitary	BBS4	0.27	0.02	enet	21	0.05	2.1e-02	-5.10	-7.5	8.3e-14	0.07	0.09	0.15	FALSE
6	GTEx	Nerve Tibial	MYO9A	0.13	0.13	lasso	3	0.11	2.1e-08	-5.44	5.6	1.8e-08	-0.02	0.00	1.00	FALSE
2	GTEx	Adipose Subcutaneous	MYO9A	0.06	0.03	lasso	2	0.01	4.7e-02	-5.36	5.2	2.1e-07	-0.06	0.04	0.88	FALSE