Best TWAS P=9.39e-08 · Best GWAS P=5.44e-10 conditioned to 5.11e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | ANKS3 | 0.09 | 0.05 | enet | 22 | 0.03 | 2.7e-03 | -4.8 | -5.3 | 1.4e-07 | -0.31 | 0.42 | 0.21 | FALSE |
| 2 | GTEx | Thyroid | RP11-95P2.1 | 0.15 | 0.10 | lasso | 5 | 0.10 | 3.9e-08 | -5.5 | 5.2 | 2.6e-07 | 0.09 | 0.07 | 0.93 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | NUDT16L1 | 0.06 | 0.01 | lasso | 4 | 0.02 | 1.1e-02 | -4.9 | 5.3 | 9.4e-08 | -0.02 | 0.01 | 0.45 | TRUE |