TWAS
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chr16:3,608,256-5,479,168
Best TWAS P=9.39e-08 · Best GWAS P=5.44e-10 conditioned to 5.11e-09
3.5M
4M
4.5M
5M
5.5M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Thyroid Carcinoma
NUDT16L1
0.06
0.01
lasso
4
0.02
1.1e-02
-4.9
5.3
9.4e-08
-0.02
0.01
0.45
TRUE
2
GTEx
Thyroid
RP11-95P2.1
0.15
0.10
lasso
5
0.10
3.9e-08
-5.5
5.2
2.6e-07
0.09
0.07
0.93
TRUE
1
GTEx
Cells Transformed fibroblasts
ANKS3
0.09
0.05
enet
22
0.03
2.7e-03
-4.8
-5.3
1.4e-07
-0.31
0.42
0.21
FALSE