Best TWAS P=4.2e-08 · Best GWAS P=5.88e-07 conditioned to 0.893
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | ENO3 | 0.08 | 0.06 | lasso | 5 | 0.05 | 4.3e-07 | -4.8 | -5.1 | 2.7e-07 | 0.86 | 0.02 | 0.97 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | INCA1 | 0.02 | 0.02 | blup | 54 | 0.02 | 3.7e-05 | -4.9 | -5.5 | 4.2e-08 | 0.90 | 0.01 | 0.98 | TRUE |