Hub : Genes

ENO3

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0780 0.0250 4.9e-05 0.065 0.034 0.038 0.035 0.053 2.4e-08 4.8e-05 1.7e-05 3.7e-05 4.3e-07
2 GTEx Artery Aorta 0.2510 0.0520 2.6e-11 0.331 NA 0.313 NA 0.322 7.4e-19 NA 8.7e-18 NA 2.6e-18
3 GTEx Brain Caudate basal ganglia 0.2390 0.0800 7.7e-04 0.106 NA 0.111 NA 0.131 5.9e-04 NA 4.5e-04 NA 1.4e-04
4 GTEx Brain Cerebellum 0.2350 0.1000 8.6e-03 -0.005 NA -0.005 NA 0.008 4.9e-01 NA 5.0e-01 NA 1.8e-01
5 GTEx Cells Transformed fibroblasts 0.0690 0.0310 7.5e-03 0.056 NA 0.058 NA 0.061 5.2e-05 NA 3.5e-05 NA 2.2e-05
6 ROSMAP Brain Pre-frontal Cortex 0.1331 0.0314 1.3e-10 0.124 0.108 0.144 0.129 0.132 1.2e-15 9.5e-14 4.8e-18 3.0e-16 1.4e-16
7 YFS Blood 0.0258 0.0099 1.2e-03 0.002 0.009 0.003 0.009 0.003 8.1e-02 4.5e-04 3.1e-02 4.9e-04 3.6e-02
8 TCGA Lung Adenocarcinoma 0.0365 0.0211 1.8e-03 0.033 0.021 0.012 NA 0.030 9.2e-05 1.4e-03 1.2e-02 NA 1.7e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.6 0.9 2.0 -1.1 -1.0 -0.6 0.6 -0.7 -1.4 1.0 1.1
Bipolar Disorder or Schizophrenia 0.1 0.3 2.2 -0.1 0.0 0.1 -0.1 -0.1 -0.4 1.5 0.4
Depressed Affect (Nagel 2018) 1.4 3.0 5.7 -1.9 -1.8 -1.9 -2.4 -1.9 -1.5 1.1 1.0
Depression (Nagel 2018) 5.4 8.1 11.1 -3.0 -3.2 -3.3 -3.3 -3.1 -3.0 -1.6 1.7
Intelligence (Savage-Jansen 2018) 0.6 1.8 2.7 1.6 1.4 0.7 1.1 1.2 1.5 1.6 -1.5
Neuroticism (Nagel 2018) 1.0 2.3 5.2 -1.5 -1.5 -1.7 -2.3 -1.7 -1.4 -0.1 1.0
Schizophrenia (2018) 0.2 0.5 1.1 0.7 0.8 0.6 -0.7 0.4 0.6 1.1 -0.3
Schizophrenia vs Biploar Disorder 2.9 3.8 5.3 -2.2 -1.7 -1.6 -2.3 -2.0 -2.2 -1.3 2.1
Worry (Nagel 2018) 2.3 4.9 6.2 -2.5 -2.4 -2.2 -2.0 -2.3 -2.3 -1.9 2.1
Alzheimer’s Disease (in mother) 1.8 2.0 4.8 1.4 1.7 1.8 0.4 1.5 1.1 2.2 -0.1
Alzheimer’s Disease (in father) 0.5 0.5 1.7 -0.3 -0.1 0.1 -0.5 -0.0 -0.7 1.2 1.3
Alzheimer’s Disease (including proxy) 3.3 4.7 12.5 1.8 2.4 2.8 0.7 2.5 1.2 3.5 0.6
Crohns Disease (2017) 0.2 0.5 1.5 0.8 0.7 1.2 0.4 0.9 0.5 -0.1 -0.4
Irritable Bowel Disease (IBD) 0.3 0.8 1.4 -1.0 -1.0 -0.4 -1.2 -0.8 -1.1 0.6 0.9
Ulcerative Colitis (UC) 2.6 4.9 7.7 -2.8 -2.4 -2.0 -1.9 -2.3 -2.8 0.2 2.3
Major Depression (MDD) 0.1 0.1 0.4 -0.2 -0.2 0.0 0.6 -0.5 0.3 0.2 0.3
Reaction Time 1.3 2.5 5.4 -1.9 -1.9 -1.1 -0.6 -1.4 -2.3 0.3 2.0
Verbal and Numeric Reasoning (VNR) 2.8 6.7 10.6 3.2 2.8 2.1 3.3 2.8 2.9 -0.0 -2.1
Breast Cancer 0.2 0.4 0.6 0.6 0.5 0.5 0.7 0.3 0.7 -0.8 -0.7
Ovarian Cancer 0.7 0.9 3.4 0.1 0.7 1.4 1.9 0.6 0.5 -0.1 1.0
Prostate Cancer 0.2 0.3 0.7 0.6 0.7 0.6 -0.7 0.5 0.8 -0.0 -0.3
Age at First Birth 0.3 0.4 1.1 -0.7 -0.2 0.3 -0.4 -0.2 -0.8 0.9 1.1
Bipolar Disorder (2011) 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 -0.6
Body Mass Index (BMI) (2010) 2.8 3.8 6.7 1.9 1.9 2.3 2.6 2.2 1.5 1.8 -1.0
Coronary Artery Disease (CAD) 0.3 0.3 1.5 -0.7 -0.3 -0.1 -1.2 -0.4 -0.6 0.0 0.3
Crohns Disease (2012) 0.5 0.8 2.0 1.1 0.9 1.4 0.6 1.0 0.1 -1.1 -0.3
Mean Putamen Volume 0.2 0.2 0.6 0.3 0.3 0.1 0.7 0.5 -0.0 -0.8 -0.6
Fasting Glucose 0.4 0.5 1.3 0.8 0.9 0.6 0.6 0.9 0.3 1.2 -0.0
HbA1C 3.5 3.8 11.1 2.6 2.0 0.7 0.3 1.9 1.9 0.5 -3.3
HDL Cholesterol 0.1 0.1 0.4 -0.2 -0.1 0.3 0.3 0.2 -0.4 0.2 0.7
LDL Cholesterol 0.4 0.6 2.4 -0.8 -0.4 -0.5 -1.5 -0.6 -0.4 0.9 0.2
Lupus 2.2 3.4 8.7 2.1 1.7 0.9 0.5 1.7 2.6 -0.1 -3.0
Neuroticism (2016) 2.8 4.1 6.9 -2.6 -2.5 -1.8 -1.3 -2.2 -1.7 -1.0 2.4
Primary Biliary Cirrhosis 0.9 1.3 2.2 -1.2 -1.2 -1.4 -1.3 -1.5 -1.2 0.0 0.2
Rheumatoid Arthritis 2.4 3.3 6.5 2.2 1.9 1.2 0.6 1.8 2.3 1.0 -2.6
Schizophrenia (2014) 0.6 1.3 3.7 -1.1 -0.9 -0.9 -1.9 -1.1 -1.0 1.2 0.8
Triglycerides 0.3 0.5 2.5 0.3 0.4 0.2 -0.2 0.0 0.6 1.6 -0.7
Type 2 Diabetes (T2D) (2012) 0.3 0.3 0.5 0.6 0.6 0.7 0.4 0.5 0.7 -0.6 -0.2
Ulcerative Colitis 3.8 5.6 8.5 -2.9 -2.6 -2.1 -2.6 -2.5 -2.8 0.3 2.1
Blood Eosinophil Count 0.9 6.6 11.8 3.4 3.1 2.6 1.4 2.8 3.0 -0.7 -2.3
Blood Platelet Count 3.6 41.3 65.8 -6.5 -7.5 -5.9 0.7 -6.6 -8.1 -5.7 7.3
Blood Red Count 0.6 5.9 14.7 1.1 2.4 3.8 2.3 2.3 0.4 3.0 2.4
Blood White Count 2.8 20.8 40.1 5.0 5.1 5.6 6.3 5.3 3.6 -1.0 -1.6
Heel T-Score 0.3 2.4 5.2 1.4 2.0 2.3 -0.3 1.6 1.4 1.8 -0.4
BMI 1.7 9.7 17.2 3.3 4.0 4.2 2.1 3.3 2.2 3.5 -1.0
Height 0.4 7.2 17.2 -3.6 -3.0 -1.5 -1.2 -2.3 -3.1 -0.4 4.2
Waist Hip Ratio (WHR) 0.1 0.6 1.4 -0.2 0.6 1.2 -1.1 0.8 -0.3 1.2 0.3
Systolic Blood Pressure 0.4 1.8 4.2 1.4 1.6 2.1 0.8 1.7 0.6 1.0 -0.7
Smoking Status 2.9 7.0 14.6 3.2 3.1 1.7 0.2 3.2 2.8 0.9 -3.8
Allergy or Eczema 0.0 0.1 0.4 0.1 0.3 0.4 -0.1 0.1 0.2 0.6 0.3
Cardiovascular Disease 1.6 5.2 8.9 2.8 3.0 2.8 1.7 2.5 2.2 0.9 -1.7
Hypothyroidism (self reported) 1.7 3.8 10.2 2.0 1.8 1.7 3.2 1.7 1.1 -1.8 -1.7
Respiratory disease 0.3 0.7 4.2 0.4 -0.3 -0.5 0.6 -0.1 -0.3 -2.0 -0.7
Type 2 Diabetes (T2D) (2018) 4.0 7.4 12.0 3.2 3.5 3.1 2.0 2.9 2.7 1.2 -2.5
Lung FEV1/FVC ratio 0.2 0.8 1.7 0.4 1.2 1.3 -0.8 1.1 0.3 1.1 0.3
Lung FVC 0.7 3.3 5.0 2.2 1.9 1.6 1.7 2.0 2.0 -1.6 -1.5
Neuroticism 0.4 1.0 2.3 -0.9 -1.0 -1.2 -1.5 -1.0 -1.1 0.1 0.3
Chronotype (morning person) 2.0 4.5 8.5 -1.7 -2.2 -2.9 -1.9 -2.5 -2.5 -1.8 0.6
Hair Pigment 0.0 1.4 4.2 1.2 1.1 1.1 0.5 0.7 0.7 -2.0 -1.4
Tanning 0.1 0.6 1.3 0.8 0.8 1.0 0.4 1.2 0.9 0.2 -0.5
Hand grip strength (left) 0.4 1.1 2.4 0.9 1.0 1.5 1.3 1.4 0.7 -0.8 -0.4
Number of treatments/medications taken 0.9 1.6 2.8 1.4 1.1 0.7 1.7 0.9 1.3 -1.4 -1.4
Average weekly spirits intake 0.1 0.1 0.9 0.3 0.1 0.1 -0.1 -0.0 -0.9 0.0 -0.2
Sensitivity / hurt feelings 0.2 0.4 1.2 -0.1 -0.5 -0.8 -0.4 -0.4 -1.1 -0.5 -0.4
Frequency of depressed mood in last 2 weeks 0.9 1.2 2.6 -1.0 -1.2 -1.6 -1.2 -1.0 -1.4 -0.3 0.5
Hearing difficulty/problems: Yes 2.0 3.0 6.1 -1.5 -1.6 -1.9 -1.8 -1.7 -2.5 -1.7 0.5
Relative age of first facial hair 0.2 0.4 1.9 0.2 0.5 0.6 -0.4 0.2 0.6 -1.4 -0.2
Other serious medical condition/disability diagnosed by doctor 1.3 1.6 3.0 1.7 1.4 1.0 0.5 1.0 1.3 1.5 -1.4
Ever used hormone-replacement therapy (HRT) 0.4 0.6 2.1 0.2 -0.1 -1.1 -1.5 -0.4 -0.4 0.6 -0.8
Ever had hysterectomy (womb removed) 1.2 1.3 2.1 -1.2 -1.2 -1.1 -0.7 -1.4 -1.2 -0.9 1.2
Systolic blood pressure, automated reading 0.7 1.9 3.4 1.9 1.8 1.5 -0.1 1.4 0.9 0.9 -1.8
Eye problems/disorders: Diabetes related eye disease 3.3 3.7 7.6 1.6 2.2 2.7 2.8 2.1 1.6 -0.4 0.0
Angina 0.1 0.2 1.1 -0.0 -0.2 -0.2 1.1 -0.2 0.1 -0.4 0.3
Medication for hormone replacement therapy 2.3 2.5 6.0 1.7 1.6 1.3 2.4 1.8 1.3 -0.7 -1.4
Vitamin and mineral supplements 2.6 3.5 6.6 2.2 2.6 2.4 1.0 2.2 1.4 1.5 -0.6
Supplements: Zinc 0.8 0.9 2.5 -1.0 -1.3 -1.6 -0.3 -1.0 -0.9 0.0 0.3
Medication: Co-codamol 2.7 3.2 4.9 -1.6 -1.8 -2.2 -2.1 -1.7 -1.9 1.9 0.4
Medication: Metformin 1.9 2.7 4.0 1.9 2.0 1.8 2.0 1.7 1.6 0.7 -1.3
Diabetes (father) 0.6 0.7 2.1 0.5 0.7 0.8 1.5 0.7 0.2 -1.1 0.5
Diabetes (mother) 0.4 0.5 1.6 -0.5 -0.6 -1.0 -0.4 -0.7 -0.1 1.3 -0.2
Severe depression (siblings) 0.3 0.3 1.2 0.1 0.5 0.5 0.2 0.4 -0.4 1.1 0.8
Pack years adult smoking proportion 0.3 0.4 0.6 0.7 0.6 0.7 0.7 0.8 -0.1 0.8 -0.3
Impedance of leg (right) 0.8 4.0 5.8 -2.1 -2.4 -2.1 -1.3 -1.8 -2.3 -2.3 1.2
Leg fat-free mass (left) 1.1 5.6 10.2 2.2 2.6 3.2 1.8 2.5 2.3 2.8 -0.3
Trunk fat percentage 1.1 4.6 7.1 2.2 2.5 2.7 2.4 2.0 1.8 2.4 -0.7
Hand grip strength (right) 0.2 0.6 1.8 0.1 0.5 1.4 0.7 0.8 -0.2 -0.4 1.1
Townsend deprivation index at recruitment 0.5 0.7 3.2 0.7 0.8 0.6 0.4 0.6 0.3 1.8 -0.3
Current tobacco smoking 1.8 3.0 6.4 2.3 1.9 1.1 0.5 1.9 1.4 -1.3 -2.5
Average weekly fortified wine intake 2.5 2.9 4.7 -2.0 -1.8 -1.1 0.6 -2.0 -1.6 -1.9 2.2
Maternal smoking around birth 1.1 1.6 3.5 1.5 1.6 1.5 0.5 0.8 1.9 0.4 -1.2
Fed-up feelings 0.7 1.3 7.4 -0.6 -0.3 -0.1 -1.3 -0.3 -0.6 2.7 0.8
Frequency of unenthusiasm / disinterest in last 2 weeks 2.6 3.4 8.0 -1.7 -2.0 -2.2 -2.8 -2.0 -1.7 0.0 0.5
Relative age voice broke 0.1 0.1 0.9 -0.0 0.1 -0.1 -1.0 -0.3 -0.4 0.0 0.0
Taking other prescription medications 1.3 2.1 6.0 1.8 1.0 0.0 1.4 0.7 1.4 -1.4 -2.4
Age when periods started (menarche) 0.4 1.0 3.0 -0.4 -0.7 -1.1 -1.7 -0.9 0.1 -0.7 -1.3
Bilateral oophorectomy (both ovaries removed) 0.3 0.4 1.4 -0.7 -0.1 0.1 -0.4 -0.2 -0.7 0.8 1.2
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.0 2.0 0.9 1.3 0.8 -0.9 1.1 0.9 1.4 -0.7
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 0.9 0.1 0.0 0.7 0.9 -0.2 0.9 -0.5 0.5
Qualifications: CSEs or equivalent 2.2 2.9 4.6 2.1 1.8 1.7 1.8 1.8 1.2 0.6 -2.0
Serious illness, injury or assault to yourself 1.2 1.4 2.2 1.3 1.5 1.3 0.9 1.3 1.2 1.0 -0.7
High blood pressure 0.1 0.3 0.9 0.5 0.7 0.3 0.4 -0.0 0.4 -0.9 -0.5
Hayfever, allergic rhinitis or eczema 0.1 0.3 0.8 -0.5 -0.3 -0.3 -0.3 -0.6 -0.6 0.4 0.9
Multivitamins +/- minerals 5.1 6.5 10.4 -3.2 -3.2 -2.7 -1.1 -2.9 -2.2 -2.1 2.1
Stomach or abdominal pain in last month 0.2 0.3 0.5 0.7 0.6 0.5 0.7 0.5 0.2 0.2 -0.4
Supplements: Glucosamine 0.4 0.5 0.8 -0.9 -0.9 -0.8 0.0 -0.8 -0.7 0.4 0.7
Diverticular disease/diverticulitis (self-reported) 0.7 0.8 2.7 1.0 0.9 0.9 1.6 0.9 0.0 -0.6 -0.1
Medication: Atenolol 4.5 5.6 8.3 -2.9 -2.5 -2.1 -1.3 -2.6 -2.4 -2.3 2.6
Medication: Levothyroxine sodium 2.9 4.9 13.4 2.4 2.0 1.6 3.7 2.0 1.5 -1.6 -2.2
Sitting height 0.1 0.7 2.5 -0.9 -0.4 0.3 -1.1 -0.4 -0.6 0.9 1.6
Chronic bronchitis/emphysema (father) 0.7 0.9 1.6 -0.9 -1.2 -1.3 -0.9 -1.1 -0.7 -0.6 0.4
High blood pressure (mother) 0.4 0.6 1.8 -0.0 -0.4 -1.1 -1.0 -0.8 0.2 1.4 -0.2
Body mass index (BMI) 2.0 8.4 12.5 3.2 3.5 3.4 2.1 2.9 2.4 3.4 -1.5
Impedance of leg (left) 0.9 4.2 6.0 -2.3 -2.5 -2.1 -1.4 -2.0 -2.3 -2.1 1.4
Leg predicted mass (left) 1.1 6.0 10.9 2.3 2.8 3.3 1.9 2.6 2.4 2.8 -0.4
Trunk fat mass 1.3 5.5 9.2 2.3 2.7 3.0 2.4 2.3 2.0 2.8 -0.6
Waist circumference 1.8 6.4 11.5 2.6 3.1 3.4 1.7 2.7 2.1 2.9 -0.9
Number of incorrect matches in round 1.8 3.0 7.3 -1.6 -1.8 -1.8 -1.4 -1.8 -1.3 -2.7 1.2
Past tobacco smoking 2.8 5.2 13.1 -2.6 -2.3 -1.1 0.1 -2.3 -2.5 -1.9 3.6
Alcohol usually taken with meals 1.7 2.8 5.7 -2.0 -2.1 -1.5 -0.5 -1.5 -2.4 -0.4 1.7
Nervous feelings 1.1 2.0 3.0 -1.4 -1.7 -1.7 -0.7 -1.4 -1.5 -1.5 1.1
Frequency of tenseness / restlessness in last 2 weeks 3.4 5.2 8.0 -2.8 -2.5 -2.1 -2.0 -2.7 -2.5 0.3 2.5
Hearing difficulty/problems with background noise 1.4 2.2 4.7 -1.3 -1.3 -1.5 -1.7 -1.5 -2.2 -1.1 1.1
Hair/balding pattern: Pattern 2 0.8 1.0 3.3 1.2 1.1 0.9 -0.4 0.7 0.3 1.8 -0.7
Had menopause 1.2 1.5 4.0 -0.8 -1.0 -1.4 -1.1 -1.6 -0.6 -2.0 0.3
Had other major operations 0.8 1.0 2.9 -0.5 -0.7 -1.2 -1.1 -0.8 -1.7 -1.0 -0.3
Forced vital capacity (FVC) 0.6 2.2 4.3 1.1 1.5 2.1 0.4 2.0 1.2 2.0 0.4
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.7 2.3 0.3 0.7 0.3 -1.5 0.5 0.3 1.5 -0.1
Ever unenthusiastic/disinterested for a whole week 0.2 0.2 0.6 -0.5 -0.3 -0.1 -0.0 -0.2 -0.4 0.7 0.8
Qualifications: None of the above 0.3 0.6 1.4 -0.1 -0.6 -1.0 -0.0 -0.8 0.5 -1.2 -0.9
Financial difficulties in last 2 years 0.2 0.3 0.9 -0.4 0.0 0.5 -0.6 -0.3 -0.0 0.9 0.8
Mouth/teeth dental problems 0.9 1.4 2.6 1.2 1.3 1.6 0.6 1.5 1.1 1.1 -0.8
Heart attack 0.3 0.3 1.6 -0.2 -0.2 -0.2 0.9 -0.3 -0.0 -1.3 0.2
Allergy 0.3 0.6 1.0 0.5 0.9 0.9 -0.2 1.0 1.0 1.0 -0.1
Pain all over the body in last month 0.5 0.5 2.3 -0.6 -0.6 -0.1 0.7 -0.4 -0.7 -0.4 1.5
Diabetes (self-reported) 3.6 5.6 8.8 2.6 3.0 2.9 2.7 2.5 2.0 1.2 -1.4
Hayfever/allergic rhinitis (self-reported) 0.0 0.1 0.3 0.1 0.0 0.2 0.6 -0.1 0.1 -0.4 -0.1
Medication: Ramipril 0.4 0.5 1.7 0.4 0.0 0.0 1.3 -0.2 0.1 -1.3 -0.6
Medication: Simvastatin 0.1 0.1 0.8 -0.1 0.1 -0.1 -0.6 -0.2 -0.2 0.9 -0.0
Fluid intelligence score 0.8 1.7 2.8 1.4 1.7 1.5 1.7 1.6 1.0 0.7 -0.0
Illnesses of siblings 0.4 0.5 1.4 0.3 0.7 1.2 -0.6 0.9 0.2 0.8 0.6
Neuroticism score 0.1 0.1 0.7 0.0 0.1 0.0 -0.8 0.2 -0.4 0.5 0.0
Weight 1.1 5.4 10.2 2.1 2.6 3.2 1.8 2.3 1.9 3.1 -0.2
Impedance of arm (right) 1.0 4.4 7.2 -2.4 -2.7 -2.3 -0.4 -2.2 -1.8 -2.5 1.7
Arm fat percentage (right) 2.0 7.8 11.3 3.0 3.3 3.4 3.0 2.8 2.5 2.7 -1.4
Trunk fat-free mass 0.5 2.8 7.0 1.3 1.9 2.6 1.0 1.9 1.2 2.0 0.5
Hip circumference 1.4 5.9 10.2 2.4 2.8 3.2 2.1 2.4 2.1 2.9 -0.4
Time employed in main current job 0.7 0.8 3.1 0.4 0.6 0.8 -1.0 0.6 0.9 1.8 -0.4
Alcohol intake versus 10 years previously 0.7 1.0 5.9 -0.6 0.1 0.2 -0.1 -0.1 -0.5 2.4 1.1
Father’s age at death 1.9 2.5 5.1 -2.1 -1.5 -0.9 -1.4 -1.3 -1.9 0.5 2.2
Worrier / anxious feelings 0.7 1.3 2.3 -1.2 -0.9 -0.6 -1.5 -0.8 -1.3 -1.0 1.5
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.4 0.9 -0.5 -0.7 -0.9 -0.3 -0.6 -1.0 0.4 0.3
Falls in the last year 0.5 0.7 2.6 0.3 -0.2 -0.7 -0.1 -0.6 0.7 1.6 -1.2
Hair/balding pattern: Pattern 3 0.2 0.3 0.7 0.0 0.4 0.8 0.8 0.8 0.3 0.4 0.3
Number of live births 1.9 2.7 3.9 2.0 1.9 1.8 1.4 1.6 1.9 0.6 -1.6
Forced expiratory volume in 1-second (FEV1) 1.0 3.3 7.3 1.6 2.1 2.7 0.6 2.5 1.2 2.0 0.5
Pulse rate 2.3 3.8 5.5 -2.1 -2.2 -2.0 -2.3 -2.3 -2.0 -0.8 1.4
Happiness 0.6 0.7 2.0 -0.4 -0.7 -1.2 -1.0 -0.6 -0.4 1.4 0.1
Noisy workplace 0.6 0.7 1.5 -1.2 -1.0 -0.6 -0.5 -0.9 -0.6 0.2 1.2
Qualifications: A levels/AS levels or equivalent 0.5 1.2 8.1 0.0 0.2 0.5 -1.1 0.1 0.2 2.8 0.2
Serious illness, injury or assault of a close relative in last 2 years 2.2 2.5 3.8 1.8 1.9 1.5 0.2 1.7 1.4 1.9 -1.6
Mouth/teeth dental problems: Dentures 2.3 3.8 6.5 -1.7 -2.1 -2.6 -1.2 -2.5 -1.9 -2.0 0.8
Asthma 0.7 1.5 4.1 1.5 0.7 0.3 1.3 0.9 0.7 -1.5 -2.0
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.8 3.4 0.4 0.3 0.2 -0.5 0.3 1.3 1.9 -0.7
Medication: Cholesterol lowering 0.3 0.4 1.1 0.5 0.5 0.2 0.9 0.2 0.6 -1.1 -0.6
Depression (self-reported) 0.5 0.6 1.0 -0.9 -1.0 -0.8 -0.7 -0.9 -0.5 0.2 0.9
Medication: Lansoprazole 0.1 0.1 0.4 0.2 0.0 -0.0 0.4 0.2 -0.1 0.7 -0.3
Prospective memory result 2.0 2.5 7.1 -1.2 -1.5 -2.0 -2.7 -1.8 -0.5 -1.0 -0.7
Lung cancer (father) 1.6 1.9 9.2 -0.6 -0.7 -1.6 -3.0 -1.0 -0.1 -0.2 -1.1
Illnesses of mother 1.1 1.4 4.7 -1.6 -0.9 0.1 -0.6 -0.7 -1.4 -0.3 2.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.7 2.1 5.1 1.1 1.5 2.3 0.6 1.9 1.1 1.7 0.6
Pulse wave Arterial Stiffness index 0.1 0.2 0.5 -0.0 0.0 0.2 0.7 0.2 0.6 -0.7 -0.0
Impedance of arm (left) 1.0 4.5 7.4 -2.4 -2.7 -2.5 -0.6 -2.4 -2.0 -2.0 1.5
Arm fat mass (right) 1.8 7.5 11.6 2.8 3.2 3.4 2.5 2.7 2.4 3.2 -1.0
Trunk predicted mass 0.5 2.7 6.5 1.3 1.8 2.5 0.9 1.9 1.2 2.0 0.5
Standing height 0.2 2.0 7.7 -1.9 -1.5 -0.0 -0.5 -0.8 -1.1 -0.1 2.8
Length of working week for main job 0.9 1.0 2.7 1.4 0.8 0.5 0.0 1.0 1.0 -0.5 -1.7
Exposure to tobacco smoke at home 0.9 1.0 2.5 -1.0 -1.1 -1.0 -0.5 -1.0 -1.6 0.3 1.1
Breastfed as a baby 1.2 1.5 2.6 -1.4 -1.5 -1.1 -1.0 -1.6 -1.6 0.0 0.8
Tense / ‘highly strung’ 1.8 3.0 6.0 -1.7 -1.8 -1.8 -2.4 -1.7 -2.1 -0.0 1.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.5 1.3 -0.9 -0.9 -0.5 0.3 -0.7 -0.4 -0.5 1.1
Hair/balding pattern: Pattern 4 0.3 0.6 2.6 0.7 0.4 -0.1 0.2 0.2 0.6 -1.1 -1.6
Birth weight of first child 0.8 1.4 2.4 -1.4 -1.4 -0.9 -1.1 -1.5 -0.8 -0.2 1.6
Peak expiratory flow (PEF) 0.2 0.5 1.1 0.7 0.9 0.9 -0.0 1.0 0.2 0.9 0.1
Pulse wave reflection index 2.3 2.8 4.9 2.1 1.9 1.0 1.5 2.1 1.4 -0.5 -2.2
Ever highly irritable/argumentative for 2 days 1.4 1.6 3.9 1.0 1.1 1.7 1.3 1.5 0.4 2.0 0.2
Loud music exposure frequency 1.1 1.2 2.3 1.2 1.1 1.1 1.0 1.1 1.1 1.5 -0.2
Qualifications: O levels/GCSEs or equivalent 1.5 2.3 5.1 1.3 1.6 2.3 1.1 1.8 1.2 1.8 -0.2
Mouth/teeth dental problems: Bleeding gums 0.1 0.1 0.4 0.3 0.2 -0.0 0.5 0.2 0.6 0.5 0.0
Blood clot in the leg (DVT) 0.2 0.3 0.6 0.8 0.7 0.3 0.4 0.6 0.5 -0.3 -0.3
Medication: Paracetamol 2.2 3.7 6.0 1.7 2.3 2.5 1.5 2.2 1.8 2.1 -0.5
Headache pain in last month 0.9 1.6 5.3 1.1 0.6 -0.0 -0.5 0.7 1.2 2.3 -1.8
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 2.3 -0.2 -0.1 0.6 -0.2 0.2 -0.8 1.5 0.9
Glaucoma (self-reported) 1.5 1.7 3.6 1.6 1.5 1.0 0.6 1.5 1.9 0.4 -1.4
Gout (self-reported) 1.0 1.4 3.1 1.2 1.0 0.7 1.8 1.3 0.9 -0.9 -1.3
Hypothyroidism/myxoedema (self-reported) 1.8 3.5 11.8 1.7 1.6 1.6 3.4 1.6 1.0 -2.0 -0.9
Medication: Amlodipine 1.2 1.7 4.7 -0.7 -0.8 -1.3 -2.2 -1.4 -0.1 2.1 0.2
Medication: Ventolin 100micrograms inhaler 0.2 0.3 0.7 -0.5 -0.6 -0.3 -0.3 -0.8 -0.4 -0.8 0.4
Birth weight 1.3 2.7 5.0 -2.2 -1.8 -0.9 -1.6 -1.2 -2.0 0.4 2.2
Chronic bronchitis/emphysema (mother) 1.2 1.3 4.0 1.1 0.7 0.7 2.0 0.8 0.7 -1.4 -1.2
High blood pressure (siblings) 0.5 0.8 3.6 0.2 -0.2 -0.4 1.3 -0.3 0.2 -1.9 -0.8
Forced vital capacity (FVC), Best measure 0.2 0.8 2.5 0.4 0.7 1.2 -0.3 1.1 0.6 1.6 0.6
Body fat percentage 1.4 5.6 8.8 2.5 2.8 3.0 2.4 2.3 2.0 2.4 -1.1
Leg fat percentage (right) 1.5 5.4 8.8 2.8 3.0 2.9 1.8 2.4 1.9 1.8 -1.6
Arm fat-free mass (right) 0.9 4.5 8.8 1.9 2.4 3.0 0.9 2.3 1.7 2.9 0.0
Exposure to tobacco smoke outside home 0.3 0.4 0.9 0.7 0.7 0.3 -0.6 0.3 -0.3 1.0 -0.8
Comparative body size at age 10 0.3 0.7 1.8 -0.8 -1.1 -1.3 -0.3 -1.1 -0.4 -0.8 -0.1
Number of full brothers 0.1 0.2 1.0 0.0 -0.3 0.0 0.1 -0.5 -0.2 1.0 0.1
Worry too long after embarrassment 0.1 0.2 0.8 -0.2 -0.2 0.0 0.0 0.1 -0.4 -0.9 0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 1.0 -0.8 -0.8 -0.4 -0.1 -0.6 -0.5 0.5 1.0
Wheeze or whistling in the chest in last year 0.7 1.3 3.0 -0.9 -1.3 -1.7 -1.4 -1.4 -1.0 -0.3 -0.2
Number of children fathered 4.4 4.9 7.2 2.6 2.7 2.5 1.3 2.6 2.3 1.5 -1.8
Reason for reducing amount of alcohol drunk: Health precaution 0.6 0.7 1.8 -0.9 -0.8 -0.0 0.6 -0.5 -1.3 -0.6 1.0
Age at first live birth 0.4 0.7 2.8 0.3 0.5 0.8 -0.9 0.8 0.0 1.7 -0.2
Pulse wave peak to peak time 0.2 0.2 0.4 -0.1 -0.2 -0.2 -0.7 -0.3 -0.6 0.7 0.2
Health satisfaction 4.9 6.4 10.5 -2.7 -3.0 -3.2 -2.6 -3.2 -2.0 -0.3 1.7
Shortness of breath walking on level ground 0.5 0.5 1.5 -0.8 -0.5 -0.3 -1.2 -1.0 0.4 0.7 0.5
Qualifications: College or University degree 0.1 0.2 0.6 -0.3 -0.2 -0.1 -0.7 0.0 -0.7 0.3 0.5
Eye problems/disorders: None of the above 2.1 2.4 3.8 -1.9 -1.7 -1.1 -0.9 -1.7 -1.8 -1.2 1.6
Mouth/teeth dental problems: Loose teeth 1.3 1.6 2.6 -1.6 -1.4 -1.1 -0.8 -1.6 -0.7 -0.8 1.6
Emphysema/chronic bronchitis 0.3 0.3 1.6 -0.2 -0.4 -0.2 -0.0 -0.4 -0.6 -1.3 -0.2
Medication for pain relief, constipation, heartburn 0.8 1.4 2.5 -1.3 -1.1 -0.9 -0.6 -1.0 -1.6 -1.4 1.1
Neck or shoulder pain in last month 0.6 0.8 3.3 0.5 0.2 -0.0 0.5 0.2 1.4 0.8 -1.8
Medication: Blood pressure 0.3 0.5 2.7 -0.0 0.0 -0.6 -0.4 -0.4 0.6 -1.6 -0.7
Angina (self-reported) 0.2 0.3 1.8 0.0 -0.0 -0.1 1.3 -0.0 0.2 -0.6 0.3
Migraine (self-reported) 0.2 0.3 1.4 0.1 -0.4 -0.7 0.1 0.2 -0.0 0.2 -1.2
Medication: Ibuprofen 0.6 0.7 1.8 0.6 0.7 0.9 -0.1 0.8 1.3 1.1 -0.6
Medication: Allopurinol 1.8 2.5 4.2 1.9 1.4 1.1 1.8 1.7 1.4 0.1 -2.1
Medication: Omeprazole 0.2 0.3 1.3 0.0 -0.1 -0.4 -0.5 0.1 -0.6 -1.1 -0.1
Medication: Seretide 50 evohaler 0.6 0.7 2.2 0.8 0.3 0.2 1.4 0.4 0.1 -1.5 -0.9
Mean time to correctly identify matches 2.3 4.5 7.2 -2.5 -2.6 -2.1 -1.1 -2.3 -2.7 -0.9 1.9
Heart disease (mother) 1.3 1.6 4.0 1.3 1.0 0.2 0.2 0.5 1.8 2.0 -1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.3 0.3 0.9 0.6 0.5 0.2 0.9 0.4 0.7 0.6 -0.6
Whole body fat mass 1.4 5.8 9.1 2.5 2.8 3.0 2.3 2.4 2.1 2.8 -0.9
Leg fat mass (right) 2.2 8.4 13.2 3.2 3.5 3.6 2.2 3.0 2.6 3.0 -1.5
Arm predicted mass (right) 0.7 3.7 7.5 1.8 2.2 2.7 1.0 2.1 1.6 2.4 -0.0
Pulse rate, automated reading 5.5 17.7 26.4 -5.1 -4.9 -4.0 -3.1 -5.0 -4.5 -2.0 4.1
Alcohol intake frequency. 0.5 1.2 2.3 0.5 1.1 1.5 1.5 1.1 0.5 1.4 0.6
Comparative height size at age 10 0.5 2.6 6.1 -2.0 -1.8 -1.4 -1.0 -1.4 -1.6 -0.5 2.5
Number of full sisters 0.2 0.2 0.8 -0.4 -0.4 -0.1 0.4 -0.3 -0.9 -0.6 0.2
Suffer from ‘nerves’ 0.9 1.5 2.6 -1.4 -1.1 -0.8 -1.5 -0.9 -1.6 0.1 1.6
Overall health rating 0.5 1.0 2.8 -0.8 -1.1 -1.7 -0.9 -1.5 -0.1 0.5 -0.2
Chest pain or discomfort 0.1 0.1 0.3 -0.4 -0.3 -0.3 0.2 -0.5 -0.3 0.2 0.6
Had major operations 0.2 0.2 0.6 0.2 -0.0 -0.6 -0.8 -0.2 -0.2 0.1 -0.7
Age at last live birth 1.2 1.7 3.5 0.9 1.4 1.4 -1.5 1.5 0.9 1.9 -0.8
Family relationship satisfaction 0.8 1.0 1.7 -1.0 -1.1 -1.3 -0.4 -1.1 -0.9 0.9 1.2
Leg pain on walking 0.3 0.4 0.9 -0.9 -0.6 -0.5 -0.7 -0.9 0.3 -0.4 0.3
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 4.4 -0.1 0.1 0.5 -0.4 -0.0 -0.2 2.1 0.2
Commuting to job workplace: Car/motor vehicle 3.5 4.0 7.0 2.4 2.4 2.2 1.1 2.0 2.6 0.9 -1.7
Illness, injury, bereavement, stress in last 2 years 1.8 2.2 6.3 -1.2 -1.6 -1.9 -0.6 -1.2 -1.3 -2.5 0.6
Medication: Aspirin 0.6 0.8 1.9 -0.5 -0.9 -1.4 -1.3 -1.1 -0.6 -0.7 -0.2
Supplements: Vitamin C 0.4 0.5 2.9 -0.0 -0.4 -0.4 0.2 -0.1 -0.5 -1.7 -0.3
Knee pain experienced in last month 0.2 0.4 0.9 0.9 0.6 -0.1 -0.4 0.4 0.5 0.8 -0.8
Hypertension (Self-reported) 0.3 1.0 1.9 1.2 1.4 1.1 0.7 0.7 0.9 -0.6 -0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.3 0.8 -0.2 -0.3 -0.3 -0.6 -0.3 -0.9 0.8 -0.0
Illnesses of father: Heart disease 0.3 0.5 1.9 -0.3 -0.3 -1.0 -0.5 -0.4 -1.4 0.1 0.4
Illnesses of siblings: Diabetes 1.1 1.3 4.2 1.3 0.4 0.0 1.7 0.5 1.0 -0.2 -2.1
Smoking status: Previous 2.3 3.5 7.1 1.8 1.6 0.9 0.0 1.7 2.1 2.5 -2.7
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 2.2 -1.0 -1.0 -0.0 -0.1 -0.5 -0.7 0.0 1.5
Whole body fat-free mass 0.8 4.5 9.4 1.8 2.4 3.1 1.4 2.3 1.8 2.5 0.1
Leg fat-free mass (right) 1.0 5.5 10.2 2.1 2.6 3.2 1.8 2.4 2.3 2.8 -0.2
Arm fat percentage (left) 1.7 6.8 9.5 2.7 3.0 3.1 2.7 2.5 2.2 2.9 -1.1
Average weekly red wine intake 3.4 5.0 9.7 -2.6 -2.5 -1.8 -0.9 -2.4 -3.1 -1.2 2.4
Handedness (chirality/laterality): Left-handed 0.4 0.5 1.3 0.3 -0.3 -0.5 0.7 -0.2 0.8 -1.1 -1.0
Mood swings 0.8 1.5 6.1 -0.6 -0.4 -0.7 -2.0 -0.5 -0.9 2.5 0.1
Loneliness, isolation 0.5 0.6 1.4 -1.1 -0.6 -0.3 -0.6 -0.4 -1.1 0.7 1.2
Long-standing illness, disability or infirmity 0.3 0.5 1.2 -0.2 -0.4 -1.1 -1.0 -0.6 -0.3 0.8 -0.6
Ever had bowel cancer screening 0.8 0.9 2.5 -0.2 -0.8 -1.6 -0.5 -1.1 0.0 -1.2 -1.0
Diabetes diagnosed by doctor 3.8 6.2 9.9 2.7 3.1 3.0 2.6 2.7 2.1 1.5 -1.6
Ever had stillbirth, spontaneous miscarriage or termination 2.3 2.5 4.7 -1.4 -1.9 -2.2 -1.2 -2.0 -1.9 -0.6 -0.0
Friendships satisfaction 0.5 0.7 1.7 -0.7 -1.0 -1.3 -0.6 -0.9 -0.8 0.4 0.2
Qualifications: nursing, teaching 1.1 1.6 3.2 -1.1 -1.2 -1.5 -1.4 -1.3 -1.8 -0.6 1.0
Commuting to job workplace: Walk 0.9 0.9 1.9 -1.4 -1.3 -1.1 0.3 -1.2 -0.4 0.0 1.0
Eye problems/disorders: Cataract 0.1 0.1 0.6 -0.3 -0.2 -0.8 0.1 -0.2 -0.6 -0.0 0.2
Mouth/teeth dental problems: Mouth ulcers 0.3 0.4 1.7 -0.1 0.2 -0.2 -1.3 -0.1 -0.5 1.2 0.0
Medication for cholesterol 1.2 1.8 3.2 -1.8 -1.6 -1.6 -1.5 -1.5 -0.5 -0.7 0.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 1.9 -0.5 -0.8 -1.0 -1.1 -0.8 -0.3 1.4 0.1
Back pain experienced in last month 1.0 1.4 2.9 1.2 0.9 0.4 1.7 0.7 1.4 1.7 -1.0
Mineral and other dietary supplements 4.3 5.8 9.1 3.0 2.8 2.4 1.0 2.6 2.7 1.4 -2.6
Breast cancer (self-reported) 0.1 0.2 0.5 0.2 0.4 0.0 -0.4 0.7 -0.4 0.2 -0.6
Asthma (self-reported) 0.6 1.2 3.3 1.3 0.5 0.2 1.1 0.7 0.5 -1.5 -1.8
Osteoporosis (self-reported) 0.4 0.5 1.0 -0.5 -0.8 -0.9 0.2 -1.0 -0.7 -0.8 -0.2
Osteoarthritis (self-reported) 0.5 0.6 1.1 0.9 0.8 0.9 1.1 0.7 0.7 -0.5 -0.5
Medication: Aspirin 0.6 0.8 2.1 -0.5 -0.8 -1.3 -1.5 -1.1 -0.6 -0.0 0.1
Medication: Gliclazide 0.6 0.7 2.4 1.0 0.7 0.7 0.5 0.4 0.7 0.2 -1.6
Illnesses of father: None of the above (group 1) 0.7 0.8 2.2 -1.1 -1.1 -0.1 0.4 -0.8 -0.3 -1.5 0.9
Smoking status: Current 1.7 2.7 5.5 2.1 1.8 1.0 0.5 1.9 1.0 -1.7 -2.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 1.6 0.2 0.6 0.7 -1.3 0.5 -0.1 0.8 0.5
Whole body water mass 0.8 4.4 9.2 1.8 2.4 3.0 1.4 2.3 1.8 2.7 0.2
Leg predicted mass (right) 1.0 5.6 10.6 2.1 2.7 3.2 1.8 2.5 2.3 2.7 -0.1
Arm fat mass (left) 1.8 7.2 11.4 2.7 3.1 3.4 2.5 2.6 2.3 3.2 -0.9
Number of self-reported non-cancer illnesses 0.4 0.7 2.0 1.1 0.7 0.0 1.2 0.3 0.3 -0.5 -1.4
Average weekly champagne plus white wine intake 0.3 0.4 1.3 0.2 -0.3 -0.7 -0.9 -0.3 0.2 0.3 -1.1
Miserableness 0.3 0.5 0.8 -0.6 -0.7 -0.7 -0.7 -0.6 -0.9 0.7 0.5
Guilty feelings 0.6 0.9 1.7 0.9 0.8 1.0 1.1 0.9 1.3 -0.6 -0.9
Wears glasses or contact lenses 1.4 1.6 3.3 -1.2 -1.8 -1.8 -0.2 -1.7 -1.2 0.1 0.8
Ever taken oral contraceptive pill 0.8 0.9 2.9 0.9 1.0 1.2 0.2 0.8 0.0 1.7 -0.2
Hearing aid user 1.3 1.4 2.9 -1.7 -1.6 -1.3 0.0 -1.7 -0.7 0.2 0.8
Mother’s age at death 0.2 0.2 0.8 -0.7 -0.4 -0.0 -0.3 -0.4 -0.0 -0.1 0.9
Financial situation satisfaction 4.6 5.6 7.8 -2.8 -2.6 -2.3 -2.2 -2.5 -2.4 1.1 2.7
Tinnitus: Yes, now most or all of the time 1.3 1.5 3.3 -1.6 -1.2 -0.7 -0.4 -1.2 -1.8 0.2 1.8
Commuting to job workplace: Public transport 0.4 0.5 1.4 -0.6 -0.8 -1.2 0.1 -0.7 -0.8 -0.3 0.3
Eye problems/disorders: Glaucoma 2.3 2.7 5.1 1.9 1.8 1.2 0.4 2.0 2.3 1.2 -1.7
Medication: Blood pressure 0.0 0.1 0.3 0.3 0.1 0.1 -0.1 -0.3 -0.5 0.0 0.1
Pain type(s) experienced in last month: Hip pain 0.1 0.2 0.9 -0.1 0.4 0.4 -0.0 0.2 0.2 1.0 0.3
Supplements: Fish oil (including cod liver oil) 3.9 5.0 8.1 -2.9 -2.6 -2.4 -1.4 -2.5 -2.4 -1.4 1.9
High cholesterol (Self-reported) 1.0 1.9 3.1 1.7 1.8 1.6 0.9 1.4 1.4 -0.4 -1.1
Medication: Bendroflumethiazide 0.2 0.3 0.9 0.4 0.2 -0.2 -0.2 0.2 -0.5 -1.0 -0.9
Medication: Paracetamol 0.8 1.3 2.8 0.7 1.4 1.7 0.8 1.3 1.0 1.2 0.1
Medication: Lisinopril 0.2 0.2 0.4 0.2 0.6 0.3 -0.6 0.4 -0.0 -0.6 0.5
Medication: Atorvastatin 1.0 1.3 2.2 1.4 1.2 0.7 1.4 1.0 1.5 -0.6 -1.1
Illnesses of father: High blood pressure 0.7 0.8 1.7 -0.8 -0.9 -1.3 -0.2 -1.3 -0.9 -0.2 1.1
Alcohol drinker status: Never 0.8 0.9 2.2 -0.9 -0.7 -0.6 0.7 -0.8 -1.5 -1.0 1.1
Ever smoked 3.3 5.8 14.0 2.9 2.6 1.2 0.1 2.6 2.6 1.5 -3.7
Basal metabolic rate 1.0 5.6 11.4 2.1 2.7 3.4 1.7 2.6 2.1 2.8 -0.1
Leg fat percentage (left) 1.5 5.3 8.7 2.7 2.9 2.8 1.7 2.3 1.9 2.0 -1.6
Arm fat-free mass (left) 0.9 4.7 9.7 2.0 2.6 3.1 1.2 2.4 1.9 2.6 -0.1
Number of operations (self-reported) 0.2 0.3 1.5 0.3 0.2 -0.4 -0.7 0.0 -0.2 1.2 -0.4
Average weekly beer plus cider intake 0.7 1.1 2.0 0.7 1.4 1.3 0.4 1.2 0.8 1.4 0.1
Irritability 1.5 2.6 11.3 1.3 1.6 1.4 -0.9 1.4 0.6 3.4 -0.5
Risk taking 1.7 2.5 4.5 2.1 1.9 1.2 -0.1 2.0 1.4 0.7 -2.1
Ever had prostate specific antigen (PSA) test 0.3 0.4 0.8 -0.9 -0.7 -0.4 -0.6 -0.8 -0.4 0.3 0.7
Fractured/broken bones in last 5 years 1.3 1.7 3.0 1.4 1.3 1.2 1.3 1.4 1.7 0.8 -1.1
Age started oral contraceptive pill 2.5 3.2 8.8 -1.7 -1.5 -1.7 -3.0 -2.0 -1.7 0.8 1.1
Diastolic blood pressure, automated reading 0.3 1.0 2.1 1.3 1.4 1.4 0.4 0.9 0.4 -0.8 -0.7
Ever depressed for a whole week 0.6 0.8 1.2 1.1 0.9 0.7 1.1 1.0 0.7 0.6 -0.9
Unable to work because of sickness or disability 0.5 0.7 2.0 -0.2 0.2 0.9 0.8 0.3 0.2 1.4 1.3
Commuting to job workplace: Cycle 0.1 0.1 0.3 0.3 0.1 0.2 -0.1 0.3 0.5 -0.0 -0.5
Myopia 1.7 2.5 5.4 -1.2 -1.5 -1.9 -2.3 -1.8 -1.2 1.4 -0.5
Vascular/heart problems diagnosed by doctor 0.3 0.7 1.3 -1.0 -1.1 -0.7 -0.8 -0.5 -0.9 0.7 0.8
Cholesterol lowering medication 0.6 0.9 2.3 1.2 1.2 0.9 -0.3 0.9 0.3 1.5 -0.7
Medication: Omeprazole (e.g. Zanprol) 0.1 0.1 0.7 0.1 0.0 -0.3 -0.9 0.1 -0.4 -0.2 -0.2
Pain experienced in last month 0.8 1.3 3.5 -1.2 -1.0 0.1 0.2 -0.9 -1.2 -1.5 1.9
Supplements: Calcium 2.7 3.0 4.8 -2.2 -1.9 -1.3 -0.5 -1.9 -2.0 -1.1 2.2
Basal cell carcinoma (self-reported) 1.7 2.0 3.3 1.6 1.6 1.6 1.1 1.8 1.2 0.2 -1.5
Heart attack/myocardial infarction (self-reported) 0.3 0.3 1.4 -0.3 -0.4 -0.5 0.7 -0.5 -0.1 -1.2 0.2
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 0.9 0.9 0.9 0.5 0.4 0.7 0.6 -0.1 -0.5
Heart disease (siblings) 0.6 0.7 3.1 1.1 0.5 -0.1 0.5 0.3 0.9 0.4 -1.8
Alcohol drinker status: Previous 0.9 1.0 2.8 0.6 1.1 1.7 1.0 1.2 0.9 0.9 -0.0
Pack years of smoking 0.2 0.3 0.4 0.4 0.4 0.6 0.6 0.6 -0.2 0.7 -0.0
Impedance of whole body 1.1 5.8 9.2 -2.7 -3.0 -2.8 -1.4 -2.6 -2.6 -2.1 1.7
Leg fat mass (left) 2.0 7.6 11.7 3.0 3.3 3.4 2.1 2.8 2.5 3.0 -1.4
Arm predicted mass (left) 1.1 5.4 10.8 2.1 2.7 3.3 1.1 2.6 1.9 2.9 -0.1