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chr17:14,509,122-16,109,675

Best TWAS P=5.95e-14 · Best GWAS P=4.36e-12 conditioned to 4.37e-09

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	ROSMAP	Brain Pre-frontal Cortex	TEKT3	0.15	0.03	bslmm	496	0.06	2.3e-08	-6.0	7.5	5.9e-14	0.15	0.59	0.40	TRUE
9	YFS	Blood	CDRT4	0.20	0.20	enet	32	0.22	6.3e-71	-5.5	6.5	5.7e-11	0.10	0.94	0.06	FALSE
7	GTEx	Thyroid	AC005517.3	0.32	0.22	lasso	5	0.22	2.1e-16	-6.0	6.0	1.8e-09	0.01	0.44	0.56	FALSE
1	CommonMind	Brain Pre-frontal Cortex	TEKT3	0.18	0.21	lasso	1	0.20	2.1e-24	-6.0	6.0	2.0e-09	0.02	0.43	0.57	FALSE
4	GTEx	Lung	AC005517.3	0.11	0.10	lasso	1	0.10	8.6e-08	-6.0	6.0	2.0e-09	0.02	0.45	0.52	FALSE
3	GTEx	Breast Mammary Tissue	AC005517.3	0.20	0.12	lasso	4	0.06	3.3e-04	-6.0	5.9	3.0e-09	0.04	0.52	0.34	FALSE
2	GTEx	Adipose Subcutaneous	AC005517.3	0.11	0.07	lasso	6	0.06	6.2e-06	-6.0	5.8	5.9e-09	0.05	0.64	0.33	FALSE
6	GTEx	Skin Sun Exposed Lower leg	AC005517.3	0.17	0.19	lasso	7	0.21	6.9e-17	-6.0	5.6	2.3e-08	0.04	0.50	0.50	FALSE
5	GTEx	Skin Not Sun Exposed Suprapubic	AC005517.3	0.16	0.12	lasso	5	0.13	9.4e-08	-4.7	5.5	4.1e-08	0.04	0.78	0.18	FALSE