Best TWAS P=1.6e-13 · Best GWAS P=4.85e-12 conditioned to 0.732
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | MFF | 0.22 | 0.13 | lasso | 10 | 0.17 | 4.4e-20 | -6.9 | -7.0 | 1.8e-12 | 0.94 | 0.00 | 1.00 | FALSE |
2 | GTEx | Brain Cortex | MFF | 0.31 | 0.15 | lasso | 5 | 0.13 | 2.4e-04 | -6.9 | -7.4 | 1.6e-13 | 0.92 | 0.01 | 0.94 | TRUE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | MFF | 0.10 | 0.04 | lasso | 3 | 0.08 | 5.5e-08 | -5.9 | -5.2 | 1.7e-07 | 0.81 | 0.00 | 1.00 | FALSE |