[Hub]/) : Traits : Pulse rate, automated reading :

chr2:231,564,626-234,168,951

Best TWAS P=7.45e-22 · Best GWAS P=3.24e-23 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta B3GNT7 0.30 0.20 lasso 6 0.16 3.2e-09 -9.9 9.6 9.3e-22 -0.99 0.00 1.00 FALSE
2 GTEx Cells Transformed fibroblasts EIF4E2 0.16 0.06 lasso 3 0.05 2.2e-04 -5.6 -5.7 1.5e-08 0.04 0.01 0.98 FALSE
3 GTEx Colon Transverse EIF4E2 0.27 0.17 enet 19 0.18 7.7e-09 -5.5 5.4 6.4e-08 -0.06 0.01 0.99 FALSE
4 GTEx Colon Transverse AC073254.1 0.22 0.13 lasso 4 0.15 9.3e-08 -5.4 5.6 2.5e-08 -0.04 0.01 0.99 FALSE
5 GTEx Heart Left Ventricle EIF4E2 0.41 0.23 lasso 3 0.27 1.6e-14 -5.6 5.4 5.3e-08 -0.05 0.01 0.99 FALSE
6 GTEx Prostate B3GNT7 0.34 0.15 lasso 3 0.08 4.4e-03 -9.6 9.6 7.5e-22 -0.99 0.01 0.98 TRUE
7 GTEx Testis B3GNT7 0.31 0.06 lasso 7 0.09 5.8e-05 -9.6 8.2 2.5e-16 -0.81 0.01 0.98 FALSE
8 ROSMAP Brain Pre-frontal Cortex EIF4E2 0.12 0.07 lasso 6 0.06 9.4e-08 -5.4 -5.4 6.7e-08 0.04 0.01 0.98 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma EIF4E2 0.03 0.03 enet 8 0.04 4.4e-08 4.1 -5.9 3.6e-09 0.07 0.22 0.77 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma B3GNT7 0.03 0.01 blup 36 0.02 4.0e-03 -8.8 8.5 1.8e-17 -0.91 0.01 0.95 FALSE
11 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma EFHD1 0.11 0.01 blup 70 0.03 1.0e-02 3.3 5.5 5.0e-08 0.00 0.05 0.04 TRUE
12 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma EIF4E2 0.12 0.12 lasso 10 0.11 4.8e-07 -5.6 5.3 1.2e-07 -0.04 0.01 0.99 FALSE
13 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma TIGD1 0.09 0.07 blup 57 0.07 5.6e-05 -5.5 5.4 5.4e-08 -0.07 0.01 0.98 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma B3GNT7 0.03 0.03 blup 33 0.02 8.8e-04 4.9 -5.7 1.5e-08 0.57 0.17 0.32 FALSE
15 The Cancer Genome Atlas Brain Lower Grade Glioma EFHD1 0.05 0.01 blup 70 0.01 1.7e-02 -3.1 -5.9 3.3e-09 -0.03 0.04 0.34 TRUE
16 The Cancer Genome Atlas Brain Lower Grade Glioma EIF4E2 0.03 0.01 blup 60 0.02 2.7e-03 3.1 -5.6 1.7e-08 0.05 0.09 0.14 FALSE
17 The Cancer Genome Atlas Prostate Adenocarcinoma B3GNT7 0.05 0.06 blup 36 0.05 2.6e-06 -9.6 9.0 1.9e-19 -0.95 0.01 0.99 FALSE
18 The Cancer Genome Atlas Thyroid Carcinoma EIF4E2 0.03 0.01 blup 63 0.02 4.7e-03 4.1 -5.2 2.0e-07 0.06 0.08 0.11 FALSE