Best TWAS P=1.12e-08 · Best GWAS P=8.36e-11 conditioned to 0.00166
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | LRIG1 | 0.11 | 0.01 | lasso | 3 | 0.02 | 4.0e-03 | -5.9 | 5.7 | 1.1e-08 | -0.83 | 0.01 | 0.98 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | LRIG1 | 0.06 | 0.05 | lasso | 1 | 0.04 | 4.5e-06 | -5.6 | 5.7 | 1.6e-08 | -0.86 | 0.02 | 0.98 | FALSE |