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chr6:33,856,903-35,549,670

Best TWAS P=1.99e-11 · Best GWAS P=2.77e-10 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	C6orf106	0.29	0.21	bslmm	382	0.23	6.9e-28	-6.2	-5.4	5.8e-08	0.84	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SNRPC	0.10	0.16	lasso	4	0.15	3.6e-18	-4.8	5.2	2.2e-07	-0.65	0.92	0.08	FALSE
3	GTEx	Brain Caudate basal ganglia	SNRPC	0.19	0.15	lasso	3	0.06	7.7e-03	-5.0	5.3	9.9e-08	-0.65	0.34	0.26	FALSE
4	GTEx	Cells Transformed fibroblasts	UHRF1BP1	0.34	0.32	enet	44	0.31	2.4e-23	-5.0	-5.2	1.5e-07	0.64	0.90	0.10	FALSE
5	GTEx	Esophagus Mucosa	UHRF1BP1	0.14	0.15	enet	28	0.17	1.3e-11	-4.9	-5.2	2.0e-07	0.65	0.91	0.09	FALSE
6	GTEx	Muscle Skeletal	SNRPC	0.03	0.02	lasso	3	0.02	8.3e-03	-5.0	5.5	4.2e-08	-0.69	0.13	0.66	FALSE
7	GTEx	Muscle Skeletal	C6orf106	0.08	0.06	lasso	4	0.06	7.1e-07	-5.7	5.9	4.0e-09	-0.88	0.02	0.98	FALSE
8	GTEx	Nerve Tibial	C6orf106	0.11	0.07	enet	17	0.07	1.3e-05	-6.1	-5.3	1.1e-07	0.89	0.01	0.99	FALSE
9	GTEx	Pancreas	C6orf106	0.14	0.11	enet	11	0.13	2.8e-06	-5.5	-5.7	1.3e-08	0.89	0.02	0.98	FALSE
10	GTEx	Stomach	UHRF1BP1	0.24	0.22	enet	20	0.23	2.2e-11	-4.4	-5.2	2.2e-07	0.57	0.92	0.08	FALSE
11	GTEx	Uterus	UHRF1BP1	0.20	0.03	lasso	4	0.07	1.8e-02	-5.0	-5.1	2.9e-07	0.72	0.08	0.32	FALSE
12	GTEx	Vagina	UHRF1BP1	0.31	0.05	lasso	8	0.04	5.0e-02	-5.0	-5.2	2.4e-07	0.59	0.09	0.51	FALSE
13	NTR	Blood	C6orf106	0.03	0.02	lasso	6	0.02	7.2e-07	-6.3	-6.7	2.0e-11	0.98	0.01	0.99	TRUE
14	ROSMAP	Brain Pre-frontal Cortex	C6orf106	0.30	0.26	bslmm	372	0.33	9.3e-44	-6.3	-5.4	7.9e-08	0.86	0.01	0.99	FALSE
15	YFS	Blood	UHRF1BP1	0.18	0.34	enet	36	0.34	2.5e-117	-4.8	-5.2	1.7e-07	0.63	0.91	0.09	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	C6orf106	0.04	0.05	lasso	4	0.03	8.1e-05	-6.1	-6.1	9.3e-10	0.99	0.01	0.99	FALSE
17	The Cancer Genome Atlas	Lung Adenocarcinoma	C6orf106	0.03	0.03	lasso	3	0.01	7.6e-03	-4.3	-5.2	2.4e-07	0.79	0.01	0.89	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	SNRPC	0.05	0.05	blup	31	0.05	2.9e-05	-5.0	5.3	8.7e-08	-0.67	0.22	0.75	FALSE